• 농약과학회지
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• 제7권1호
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• pp.1-11
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• 2003

새로운 농약을 탐색하고 개발하는데 있어서 고효율 유기함성 (HTOS) 기술과 고효율 검색 (HTS) 기술 등의 발전과 더불어 컴퓨터 화학을 이용한 분자설계 (CAMD) 방법으로 보편화되고 있는 비교 분자장 분석(CoMFA)과 비교 분자 유사성 지수분석(CoMSIA) 등, 3D QSAR 기법들을 위시하여 분자 홀로그램 구조 - 활성관계 (HQSAR) 분석방법 등, QSAR 기법들을 요약하고 그 활용 사례들을 간략하게 소개하였다.

• 대한가정학회지
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• 제44권9호
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• pp.1-8
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• 2006

The purposes of the present article are to suggest pragmatism as offering a philosophical paradigm for mixed methods research, to explain the fundamental principles of mixed methodology, and to present examples of research for understanding how to apply it to family studies. Mixed methods research is the class of research where the researcher mixes or combines quantitative and qualitative techniques, methods, approaches, concepts or language into a single study. Mixed methodology has its roots in pragmatism, which is a new philosophical paradigm to criticize the traditional dualism and to endorse eclecticism and pluralism. The present article argues that mixed methods research has the potential to answer a broader and more complete range of research questions, and to provide strong evidence for a conclusion through convergence and corroboration of the qualitative and the quantitative methods.

• 품질경영학회지
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• 제40권3호
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• pp.406-414
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• 2012

Purpose: In this study, we developed a service quality audit system through analyzing service processes of airlines' cabin service. Methods: Applying the qualitative approach to service processes analysis; 'service blueprint' methodology was developed, providing airlines a blueprint for cabin service and applying the quantitative service quality audit approach called 'walk-through audit', an audit methodology tailored to airline cabin service called PCPA (Passenger Cabin Patrol Audit) was developed. Results: This study tried to apply both the qualitative and the quantitative methodologies to develop service quality audit checklist and tried to develop details to systemize them into a new methodology. Conclusion: This study will be helpful for Airline services improvement by providing 'service quality audit model', so as to find out the problems and share those with the stakeholders.

• 산경연구논집
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• 제7권1호
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• pp.11-14
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• 2016

Purpose - The study aims to show the successful application of Six Sigma in software companies for process improvement. Research design, data and methodology - A mixed methodology has been used which include both qualitative and quantitative research. In the qualitative research methodology part, a detailed and comprehensive literature study have been carried out. The literature study consists of articles, books, web materials, discussion forms and others. In the quantitative research methodology part, interviews have been conducted. Results - Six sigma is the practical application of a theoretical statistical measurement that equates to 3.4 defects per million opportunities -a position of practically zero defects for any process or service. Initially originating in Motorola Inc. in 1985 as a response to drastic quality improvement pressures from the threat of Japanese competition, it quickly gained many followers particularly G.E., Allied Signal, Ford Motor Company etc. and more recently attentions have shifted to service environments. There are still some problems and misconceptions existed about the applicability of Six Sigma in software companies. Conclusions - The paper concludes that Six Sigma can bring large benefits for software companies too. Furthermore, software companies have already started to implement Six Sigma approach, like Ericsson, Tata Consultancy Service, etc.

• 한국가스학회지
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• 제18권6호
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• pp.32-39
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• 2014

화학공장은 위험물질을 다량으로 취급하고 있어 안전시스템의 신뢰성을 확보할 수 있도록 시스템을 구축하는 것은 화학공정 설계 시 고려할 기본적 사항이다. 그러나 화학공정의 안전성을 확보하기 위해 안전시스템의 신뢰성을 지나치게 강조할 경우 상대적으로 생산시스템의 신뢰성은 떨어질 수 있다. 화학공정은 일정한 수준 이상의 안전성을 확보한 상태에서 안전시스템의 신뢰성과 생산시스템의 신뢰성을 균형 있게 유지하는 필요하다. 따라서 본 연구에서는 정량적 데이터를 근거로 화학공정의 안전성과 생산성을 동시에 확보할 수 있는 방안을 제시하고자 화학공장에 널리 사용되고 있는 가열로공정을 선정하여 정량적 위험성평가를 실시하였다. 정량적 위험성평가기법으로는 안전시스템과 생산시스템을 구분하여 각각의 시스템에 대해 신뢰도평가가 가능한 유향그래프 분석기법을 사용하였다. 정량적 위험성평가 결과 가열로공정은 온도감지기(TT)와 압력감지기(PT)를 각각 3개 설치하여 2개가 일정한 값 이상을 나타낼 때 안전시스템이 작동하도록 가열로공정을 구축하는 것이 안전성과 생산성을 동시에 확보할 수 있는 최적의 화학공정 시스템 설계 조건임을 확인하였다.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 2001년도 제40차 춘계학술대회 및 연수교육
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• pp.60-65
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• 2001

The positron emission tomography (PET) has been used for the evaluation of the characteristics of various tumors. The role of PET in oncology has been evolved from a pure research tool to a methodology of enormous clinical potential. The unique characteristics of PET imaging make sophisticated quantitation possible. Several quantitative methods, such as standardized uptake values (SUV), simplified quantitative method, Patlak graphical analysis, and Sokoloff's glucose metabolism measurement, have been used in the field of oncology. However, each quantitative method has limitations of its own. For example, the SUV has been used as a quantitative index of glucose metabolism for tumor classification and monitoring response to treatment, even though it depends on blood glucose level, body configuration of patient, and scanning time. The quantitative methods of PET are reviewed and strategy for implementing these methods are presented.

• 시스템엔지니어링학술지
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• 제17권1호
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• pp.43-52
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• 2021

The aim of this study is to propose the design suitable for sustainability evaluation model of the mobile industry considering system process (SEP). Although a quantitative evaluation was conducted on the link between the national sustainability report and the mobile industry, it was confirmed that it was difficult to identify stakeholders. So it is necessary to develop the design process suitable for the more operator-specific interfaces. The Human System Integration (HSI) methodology was proposed through linkage with work domain analysis. Agile methodology and Resilience engineering methodology were added for sustainable model design. The proposed sustainability system evaluation model is applied so that it can be easily used in all industries.

• 대한간호학회지
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• 제23권3호
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• pp.453-466
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• 1993

Quantitative methodology has been the predominent methodology utilized in research in nursing. However since the 1970s qualitative methodology has also emerged as a useful methodology and has been utilized by many researchers. But in the use of this methodology, the philosophical, epistemelogical, and theoretical backgrounds have been neglected by many researchers. This paper reports a review of the literature on methodologies, quanitative and qualitative, used in nursing, and makes suggestions for future research directions. It explains why qualitative methodology has emerged as as effective methodology in nursing and discusses how the qualitative methodology differs from the quanitative one. A comparison of the two is made based on perspectives of humane being and human behavior as well as the development of nursing science. This paper also presents several views on change in nursing science, since viewpoint not only influences the determination of the current stage of nursing science but also the shaping of the future directions of nursing science and research. Scientific revolution by Kuhn, the evolutionary perspective by Toulmin, the transition of research tradition by Laudan. and convolutionary processes are presented. However, this paper indicates that it is too early to adopt these points of view, because the history of nursing science is too short. It suggests that nursing needs pluralism in philosophy, paradigms and theory, as well as in methodology. Although we experience paradoxes in adopting different perspectives in nursing, it is wise for us to continue to include a variety of viewpoints including those to which we are not accustomed, such as qualitative methodology, since we are not yet able to decide what is best for the development of nursing science.

• Journal of Electrical Engineering and Technology
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• 제2권3호
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• pp.386-390
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• 2007

At recent times, an essential issue in the replacement of the old analogue I&C to computer-based digital systems in nuclear power plants becomes the quantitative software reliability assessment. Software reliability models have been successfully applied to many industrial applications, but have the unfortunate drawback of requiring data from which one can formulate a model. Software that is developed for safety critical applications is frequently unable to produce such data for at least two reasons. First, the software is frequently one-of-a-kind, and second, it rarely fails. Safety critical software is normally expected to pass every unit test producing precious little failure data. The basic premise of the rare events approach is that well-tested software does not fail under normal routine and input signals, which means that failures must be triggered by unusual input data and computer states. The failure data found under the reasonable testing cases and testing time for these conditions should be considered for the quantitative reliability assessment. We presented the quantitative reliability assessment methodology of safety critical software for rare failure cases in this paper.

• Asian-Australasian Journal of Animal Sciences
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• 제18권12호
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• pp.1669-1674
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• 2005

Maximum likelihood methodology was applied to analyze the efficiency and statistical power of interval mapping by using a threshold model. The factors that affect QTL detection efficiency (e.g. QTL effect, heritability and incidence of categories) were simulated in our study. Daughter design with multiple families was applied, and the size of segregating population is 500. The results showed that the threshold model has a great advantage in parameters estimation and power of QTL mapping, and has nice efficiency and accuracy for discrete traits. In addition, the accuracy and power of QTL mapping depended on the effect of putative quantitative trait loci, the value of heritability and incidence directly. With the increase of QTL effect, heritability and incidence of categories, the accuracy and power of QTL mapping improved correspondingly.