Quantitative Analysis of PET Measurements in Tumors
종양학 분야에서 양전자방출촬영을 이용한 정량분석
- Choi, Chang-Woon (Department of Nuclear Medicine, Korea Cancer Center Hospital)
- 최창운 (원자력병원 핵의학과)
- Published : 2001.05.18
Abstract
The positron emission tomography (PET) has been used for the evaluation of the characteristics of various tumors. The role of PET in oncology has been evolved from a pure research tool to a methodology of enormous clinical potential. The unique characteristics of PET imaging make sophisticated quantitation possible. Several quantitative methods, such as standardized uptake values (SUV), simplified quantitative method, Patlak graphical analysis, and Sokoloff's glucose metabolism measurement, have been used in the field of oncology. However, each quantitative method has limitations of its own. For example, the SUV has been used as a quantitative index of glucose metabolism for tumor classification and monitoring response to treatment, even though it depends on blood glucose level, body configuration of patient, and scanning time. The quantitative methods of PET are reviewed and strategy for implementing these methods are presented.