• Proceedings of the KSME Conference
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• 2008.11a
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• pp.1367-1372
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• 2008

A plate type supporting structure of a tube bundle in axial flow generates a certain band of a high frequency periodic excitation of a vortex shedding and/or a flow separation due to sharp edge of the plate thickness and a severe pressure drop due to a cross-sectional area of the supports. With a design consideration of the low vibration and a small flow resistance, the analysis method is uniquely confined to an experimental approach because a complex geometry of a cylindrical tube bundle and/or physical phenomena related to the fluid-structure interaction of tube bundle in a flow impede a theoretical or a numerical approach. A 5x5 cylindrical tube bundle with 5 supports which were discretely located along the bundle's axis was tested in the FIVPET hydraulic test loop for a design evaluation and an analysis perspectives. A high frequency flow-induced vibration of the supporting structures of the cylindrical tube bundle was measured at a outer surface of a supporting structure through a transparent flow housing by the laser dopper vibrometer. Pressure drop in-between three measurement distances was measured by the differential pressure transmitter. High frequency vibration and pressure drop fairly depends on the geometric design of supporting structure. So, these two parameters would be used as a qualitative design variables for design evaluation and analysis.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5759-5765
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• 2014

Electrical impedance tomography (EIT) is a potential supplement for mammogram screening. This study aimed to evaluate and feasibility of EIT as opposed to mammography and to determine pain perception with both imaging methods. Women undergoing screening mammography at the Radiology Department of National University of Malaysia Medical Centre were randomly selected for EIT imaging. All women were requested to give a pain score after each imaging session. Two independent raters were chosen to define the image findings of EIT. A total of 164 women in the age range from 40 to 65-year-old participated and were divided into two groups; normal and abnormal. EIT sensitivity and specificity for rater 1 were 69.4% and 63.3, whereas for rater 2 they were 55.3% and 57.0% respectively. The reliability for each rater ranged between good to very good (p<0.05). Quantitative values of EIT showed there were significant differences in all values between groups (ANCOVA, p<0.05). Interestingly, EIT scored a median pain score of $1.51{\pm}0.75$ whereas mammography scored $4.15{\pm}0.87$ (Mann Whitney U test, p<0.05). From these quantitative values, EIT has the potential as a health discriminating index. Its ability to replace image findings from mammography needs further investigation.

• Journal of Korean Medical classics
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• v.31 no.4
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• pp.27-46
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• 2018

Objectives : In this paper, we investigated the applicability of text mining to Korean Medical Classics and suggest that researchers of Medical Classics utilize this methodology. Methods : We applied text mining to the Huangdi's internal classic, a seminal text of Korean Medicine, and visualized networks which represent connectivity of terms and documents based on vector similarity. Then we compared this outcome to the prior knowledge generated through conventional qualitative analysis and examined whether our methodology could accurately reflect the keyword of documents, clusters of terms, and relationships between documents. Results : In the term network, we confirmed that Qi played a key role in the term network and that the theory development based on relativity between Yin and Yang was reflected. In the document network, Suwen and Lingshu are quite distinct from each other due to their differences in description form and topic. Also, Suwen showed high similarity between adjacent chapters. Conclusions : This study revealed that text mining method could yield a significant discovery which corresponds to prior knowledge about Huangdi's internal classic. Text mining can be used in a variety of research fields covering medical classics, literatures, and medical records. In addition, visualization tools can also be utilized for educational purposes.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.41 no.10
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• pp.779-787
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• 2013

The effects of various nozzle configurations on infrared signature are investigated for the purpose of analysing the infrared signature level of aircraft propulsion system. A virtual subsonic aircraft is selected and then a circular convergent nozzle, which meets the mission requirements, is designed. Convergent nozzles of different configurations are designed with different geometric profiles. Using a compressible Navier-Stokes-Fourier CFD code, an analysis of thermal flow field and nozzle surface temperature distribution is conducted. From the information of plume flow field and nozzle surface temperature distribution, IR signature of plume and nozzle surface is calculated through the narrow-band model and the RadThermIR code. Finally, qualitative information for IR signature reduction is obtained through the analysis of the effects of various nozzle configurations on IR signature.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.7 no.3
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• pp.248-256
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• 1995

The numerical study on the surface buoyant jets has remained of requiring more intensive investigation for problems due to the treatments of free surface, Reynolds stress/flux terms in turbulent flow and especially buoyancy effects on the turbulent fluctuation. etc. The verification of predicted results from the numerical study continues in the qualitative study. because of the lack of experimental data, which seems to be due to the difficulties in measuring the turbulent fluctuations in concentration or temperature fields. In this study, the computer program of Algebraic Stress Model has been developed to investigate the behaviours of two-dimensional surface buoyant jets with free surface boundary condition. The computational results are compared with published experimental data. By comparing these results with experimental data. it is found that this model can predict fairly well the flow characteristics of two-dimensional surface buoyant jets in the momentum-dominant region and buovancy-dominant region. Especially, it is proved that this model can predict the flow characteristics reasonably in buoyancy-dominant region stably stratified due to buoyancy effect.

• Journal of the Korean Society for Nondestructive Testing
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• v.26 no.2
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• pp.122-129
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• 2006

Shearography is one of optical methods that has been applied to nondestructive testing (NDT) and strain/stress analysis. The technique has the merit of the directly measuring relative displacement, which is insensitive to environmental vibration disturbance. Previous studies about the method have emphasized on extending its application to new fields and lack insufficient research on effective parameters for qualitative and quantitative evaluation of defects. In this paper, the influence of shearing amount on the detection of an internal defect is investigated. In experiment, slender defects along longitudinal direction of pipeline are artificially designed and detection results according to the change of shearing amount are analyzed. Based on the investigation, we propose the technique for the determination of defect size and accurate source location.

• Korean Journal of Pharmacognosy
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• v.40 no.2
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• pp.109-117
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• 2009

We examined the purity of six heparin samples by using heparinase, chondroitinase, $^{1}H-NMR$, and polyacrylamide gel electrophoresis. To obtain high molecular weight contaminants from heparin samples, heparinase I - digested samples were subjected to the exhaustive microcon filtration. The filtration process removed heparin-derived di- and oligosaccharides effectively. By combining chondroitinase ABC treatment and strong anion exchange - high performance liquid chromatography, the result showed all six samples contained chondroitin sulfate as a contaminant ranging from 1.3 to 14.9%. Among them, sample S3 showed the highest content of 14.9%, which was further analyzed by chondroitinase AC treatment to confirm chondroitin sulfate B (dermatan sulfate). $^{1}H-NMR$ chemical shifts of N-acetyl groups clearly suggested the existence of chondroitin sulfate B (sample S3) and oversulfated chondroitin sulfate (samples S2 and S4) as contaminants. In addition, polyacrylamide gel electrophoresis was useful for qualitative detection on the sample's purity. These results suggest that the tools of heparinase I and chondroitinase ABC in combination with NMR spectroscopy would give very useful information for investigation of heparin contaminants such as oversulfated chondroitin sulfate and dermatan sulfate in heparin samples.

• Wind and Structures
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• v.31 no.3
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• pp.229-240
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• 2020

In the present work, the main features of primary vortices and the vorticity concentrations downstream of vortex bursting in crossflow plane of a delta wing with a sweep angle of Λ=70° were investigated under the variation of the sideslip angles, β. For the pre-review of flow structures, dye visualization was conducted. In connection with a qualitative observation, a quantitative flow analysis was performed by employing Particle Image Velocimetry (PIV). The sideslip angles, β were varied with four different angles, such as 0°, 4°, 12°, and 20° while angles of attack, α were altered between 25° and 35°. This study mainly focused on the instantaneous flow features sequentially located at different crossflow planes such as x/C=0.6, 0.8 and 1.0. As a summary, time-averaged and instantaneous non-uniformity of turbulent flow structures are altered considerably resulting in non-homogeneous delta wing surface loading as a function of the sideslip angle. The vortex bursting location on the windward side of the delta wing advances towards the leading-edge point of the delta wing. The trajectory of the primary vortex on the leeward side slides towards sideways along the span of the delta wing. Besides, the uniformity of the lift coefficient, C_L over the delta wing plane was severely affected due to unbalanced distribution of buffet loading over the same plane caused by the variation of the sideslip angle, β. Consequently, dissimilarities of the leading-edge vortices result in deterioration of the mean value of the lift coefficient, C_L.

• Journal of Pharmaceutical Investigation
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• v.24 no.3
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• pp.115-129
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• 1994

In the present study, quantitative and qualitative histology was used to assess the effects of ibuprofen suppositories with various treatments on the rectal mucosa of rats. Two suppositories were prepared with Witepsol W35 and compared with two commercial ibuprofen suppositories Reference I (Showa Pharm.ind., Tokyo, Japan), Reference II (P.Pharm., Seoul, Korea). Single and multiple dose(dosing interval 4 hr, n=4) studies were conducted. All suppositories significantly increased epithelial cell loss, but the extent of rectal irritation was variable. These studies showed that the incorporation of ibuprofen into the suppository bases increases the morphological change in rectal tissue both for the single and multiple administrations of suppositories, but which was significantly recovered within 24 hr although the interanimal variability in scores was very substantial. Multiple administration of ibuprofen suppositories caused significant damage to rectal mucosa, but it must be considered that these were under the severe condition, that is, interval of administration (4 hr) was three times shorter than normal interval of administration and dose was fifteen times larger than usual human dose. Aluminum oxide $(Al_2O_3)$, a dispersing agent, slightly increased the irritation of rectal mucosa in rats at 5 hr and 24 hr after multiple administration, but it was possible to ignore the difference of irritation in the data at 5hr and 24hr after single administration. Finally, it was concluded that Witepsol W35 and ibuprofen had a slight rectal mucosa-irritating effect on the usual human dose, and ibuprofen suppositories prepared with Witepsol W35 or Witepsol W35, $Al_2O_3$ showed almost similar extent of rectal irritation with commercial ibuprofen products.

• Journal of Conservation Science
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• v.10 no.1 s.13
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• pp.31-37
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• 2001

The metallurgical investigation of four lumps of bronze from the third building site of the northern workshop site at the Neungsan-ri temple site in Buyeo was performed. The microstructures of a section of sample was observed by SEM and qualitative and quantitative analysis of the sample was performed by EDS. The results are as follows: Sample 1 of the lump of bronze from northern workshop site in the third building site at Neungsan-ri temple site and sample 2 are speculated to be low-quality bronze resulting from refinery of matte which formed on the process of bronze refinery. Sample 3 is speculated as a lump of bronze which is one of Cu-Sn system and the one made by alloy only with pure bronze and tin on the process of bronze refinery. Sample 4 is confirmed as a lump of bronze which is one of Cu-Sn-Pb system from alloy of tin and lead into pure bronze. It is believed that the third building site at Neungsan-ri temple site in Buyeo produced bronze matte by refinery of copper ore or produced low-quality bronze by melting matte imported from outside.