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Effect of Dietary Coenzyme $Q_{10}$ on Lipid Peroxidation in Adriamycin-treated Rats - II. Effect on Mitochondrial Coenzyme $Q_{10}$ Level and Fatty Acid Composition - (식이 중의 Coenzyme $Q_{10}$첨가가 Adriamycin을 투여한 흰쥐의 체내 지질과산화에 미치는 영향 -II. 미토콘드리아내의 Coenzyme $Q_{10}$ 수준과 지방산 조성에 미치는 영향-)

  • Seo, Jung-Sook;Han, In-Kyu
    • Journal of Nutrition and Health
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    • v.24 no.4
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    • pp.299-307
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    • 1991
  • The present study was designed to evaluate the effects of dietary coenzyme $Q_{10}$ on mitochondrial coenzyme $Q_{10}$ and fatty acid composition in adriamycin (ADR)-treated rats. Two experiments were conducted in rats. Experiment 1 was undertaken under the condition of simultaneous administration of ADR and coenzyme $Q_{10}$ for 4 weeks. Experiment 2 was undertaken under the same condition as experiment 1 after feeding the experimental diets alone without administration of ADR for 4 weeks. Heart mitochondrial coenzyme $Q_{10}$ level of rats was greatly decreased by ADR treatment. but higher level of dietary coenzyme $Q_{10}$ elevated this decrease to control ranges. Pretreatment with dietary supplementation of coenzyme $Q_{10}$ showed a significant increase in myocardial coenzyme $Q_{10}$ level. With ADR treatment. polyunsaturated fatty acids such as arachidonic acid (20 : 4) and docosahexaenoic acid (22 : 6) were decreased. However, dietary supplementation of coenzyme $Q_{10}$ modified this decrement to some extent. In both experiment 1 and 2. the polyunsaturated fatty acids/saturated and polyunsaturated fatty acids (P/S+ M) ratio of ADR-treated rats tended to be lower than that of control rats.

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SELF-RECIPROCAL POLYNOMIALS WITH RELATED MAXIMAL ZEROS

  • Bae, Jaegug;Kim, Seon-Hong
    • Bulletin of the Korean Mathematical Society
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    • v.50 no.3
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    • pp.983-991
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    • 2013
  • For each real number $n$ > 6, we prove that there is a sequence $\{pk(n,z)\}^{\infty}_{k=1}$ of fourth degree self-reciprocal polynomials such that the zeros of $p_k(n,z)$ are all simple and real, and every $p_{k+1}(n,z)$ has the largest (in modulus) zero ${\alpha}{\beta}$ where ${\alpha}$ and ${\beta}$ are the first and the second largest (in modulus) zeros of $p_k(n,z)$, respectively. One such sequence is given by $p_k(n,z)$ so that $$p_k(n,z)=z^4-q_{k-1}(n)z^3+(q_k(n)+2)z^2-q_{k-1}(n)z+1$$, where $q_0(n)=1$ and other $q_k(n)^{\prime}s$ are polynomials in n defined by the severely nonlinear recurrence $$4q_{2m-1}(n)=q^2_{2m-2}(n)-(4n+1)\prod_{j=0}^{m-2}\;q^2_{2j}(n),\\4q_{2m}(n)=q^2_{2m-1}(n)-(n-2)(n-6)\prod_{j=0}^{m-2}\;q^2_{2j+1}(n)$$ for $m{\geq}1$, with the usual empty product conventions, i.e., ${\prod}_{j=0}^{-1}\;b_j=1$.

SUBALGEBRAS OF A q-ANALOG FOR THE VIRASORO ALGEBRA

  • Nam, Ki-Bong;Wang, Moon-Ok
    • Bulletin of the Korean Mathematical Society
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    • v.40 no.4
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    • pp.545-551
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    • 2003
  • We define subalgebras ${V_q}^{mZ{\times}nZ}\;of\;V_q\;where\;V_q$ are in the paper [4]. We show that the Lie algebra ${V_q}^{mZ{\times}nZ}$ is simple and maximally abelian decomposing. We may define a Lie algebra is maximally abelian decomposing, if it has a maximally abelian decomposition of it. The F-algebra automorphism group of the Laurent extension of the quantum plane is found in the paper [4], so we find the Lie automorphism group of ${V_q}^{mZ{\times}nZ}$ in this paper.

FORMATION AND EVOLUTION OF SELF-INTERACTING DARK MATTER HALOS

  • AHN KYUNGJIN;SHAPIRO PAUL R.
    • Journal of The Korean Astronomical Society
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    • v.36 no.3
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    • pp.89-95
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    • 2003
  • Observations of dark matter dominated dwarf and low surface brightness disk galaxies favor density profiles with a flat-density core, while cold dark matter (CDM) N-body simulations form halos with central cusps, instead. This apparent discrepancy has motivated a re-examination of the microscopic nature of the dark matter in order to explain the observed halo profiles, including the suggestion that CDM has a non-gravitational self-interaction. We study the formation and evolution of self-interacting dark matter (SIDM) halos. We find analytical, fully cosmological similarity solutions for their dynamics, which take proper account of the collisional interaction of SIDM particles, based on a fluid approximation derived from the Boltzmann equation. The SIDM particles scatter each other elastically, which results in an effective thermal conductivity that heats the halo core and flattens its density profile. These similarity solutions are relevant to galactic and cluster halo formation in the CDM model. We assume that the local density maximum which serves as the progenitor of the halo has an initial mass profile ${\delta}M / M {\propto} M^{-{\epsilon}$, as in the familiar secondary infall model. If $\epsilon$ = 1/6, SIDM halos will evolve self-similarly, with a cold, supersonic infall which is terminated by a strong accretion shock. Different solutions arise for different values of the dimensionless collisionality parameter, $Q {\equiv}{\sigma}p_br_s$, where $\sigma$ is the SIDM particle scattering cross section per unit mass, $p_b$ is the cosmic mean density, and $r_s$ is the shock radius. For all these solutions, a flat-density, isothermal core is present which grows in size as a fixed fraction of $r_s$. We find two different regimes for these solutions: 1) for $Q < Q_{th}({\simeq} 7.35{\times} 10^{-4}$), the core density decreases and core size increases as Q increases; 2) for $Q > Q_{th}$, the core density increases and core size decreases as Q increases. Our similarity solutions are in good agreement with previous results of N-body simulation of SIDM halos, which correspond to the low-Q regime, for which SIDM halo profiles match the observed galactic rotation curves if $Q {\~} [8.4 {\times}10^{-4} - 4.9 {\times} 10^{-2}]Q_{th}$, or ${\sigma}{\~} [0.56 - 5.6] cm^2g{-1}$. These similarity solutions also show that, as $Q {\to}{\infty}$, the central density acquires a singular profile, in agreement with some earlier simulation results which approximated the effects of SIDM collisionality by considering an ordinary fluid without conductivity, i.e. the limit of mean free path ${\lambda}_{mfp}{\to} 0$. The intermediate regime where $Q {\~} [18.6 - 231]Q_{th}$ or ${\sigma}{\~} [1.2{\times}10^4 - 2.7{\times}10^4] cm^2g{-1}$, for which we find flat-density cores comparable to those of the low-Q solutions preferred to make SIDM halos match halo observations, has not previously been identified. Further study of this regime is warranted.

A RESERCH ON NONLINEAR (p, q)-DIFFERENCE EQUATION TRANSFORMABLE TO LINEAR EQUATIONS USING (p, q)-DERIVATIVE

  • ROH, KUM-HWAN;LEE, HUI YOUNG;KIM, YOUNG ROK;KANG, JUNG YOOG
    • Journal of applied mathematics & informatics
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    • v.36 no.3_4
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    • pp.271-283
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    • 2018
  • In this paper, we introduce various first order (p, q)-difference equations. We investigate solutions to equations which are linear (p, q)-difference equations and nonlinear (p, q)-difference equations. We also find some properties of (p, q)-calculus, exponential functions, and inverse function.

Chemical Constituents of Domestic Quercus spp. Barks (국내산 참나무속 수종 수피의 추출성분)

  • Kim, Jin-Kyu;Kwon, Dong-Joo;Lim, Soon-Sung;Bae, Young-Soo
    • Journal of the Korean Wood Science and Technology
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    • v.38 no.4
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    • pp.359-374
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    • 2010
  • This study was carried out to investigate the chemotaxonomical correlation and chemical constituents of domestic Quercus spp. barks. The barks of Q. mongolica, Q. aliena, Q. serrata, Q. acutissima, Q. dentata, and Q. variabilis were collected in the experimental forest of Kangwon National University. The combined extracts were successively fractionated with n-hexane, methylene chloride and ethyl acetate using a separation funnel. A portion of the ethyl acetate and H2O soluble materials of each species were chromatographed on a Sephadex LH-20 column using various aqueous MeOH and EtOH-hexane as washing solvents. Spectrometric analysis such as NMR and MS, including TLC, were performed to characterize the structures of the isolated compounds. Ellagic acid (0.03 g), (+)-catechin (4.59 g), taxifolin (3.35 g), and glucodistylin (20.52 g) were isolated from Q. mongolica bark. Gallic acid (0.18 g), (+)-catechin (8.52 g), (+)-gallocatechin (0.09 g), taxifolin (0.54 g), and glucodistylin (3.28 g) were characterized from Q. acutissima bark. Gallic acid (0.38 g), ellagic acid (0.11 g), (+)-catechin (2.01 g), (+)-gallocatechin (0.12 g), and glucodistylin (0.39 g) were identified from Q. dentata bark. Ellagic acid (1.51 g), (+)-catechin (21.91 g), and glucodistylin (3.91 g) were purified from Q. aliena bark. Ellagic acid (0.84 g), (+)-catechin (0.82 g), taxifolin (4.02 g), and glucodistylin (21.50) were isolated from Q. serrata bark. Gallic acid (0.24 g), caffeic acid (0.05 g), (+)-catechin (0.32 g), and glucodistylin (0.65 g) were purified from Q. variabilis bark. (+)-Catechin and glucodistylin were isolated from all the barks. Glucodistylin can be a taxonomic index on Quercus spp.

Effects of pH and Light Irradiation on Coenzyme Q10 Production Using Rhodobacter sphaeroides

  • Jeong, Soo-Kyoung;Dao, Van Thingoc;Kien, Ngyuen;Kim, Joong-Kyun
    • Fisheries and Aquatic Sciences
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    • v.11 no.4
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    • pp.219-223
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    • 2008
  • To increase the level of $CoQ_{10}$ production in mass culture, the effects of pH and light irradiation on $CoQ_{10}$ production by Rhodobacter sphaeroides were investigated in a 1-L bioreactor. $CoQ_{10}$ production was growth-associated, and the highest production of $CoQ_{10}$ (1.69 mg/g dry cell) was obtained under uncontrolled pH: this production was 1.7 times higher than that obtained at controlled pH 7. Therefore, pH was a key factor affecting $CoQ_{10}$ production. The effect of light irradiation on $CoQ_{10}$ production was negligible. This result offers an advantage for mass production of $CoQ_{10}$.

The Study of Life Styles, Dietary Habits and Nutrient Intakes of Korean Male College Students Related to the Bone Mineral Density (남자 대학생의 골밀도에 따른 생활습관과 식습관 및 영양소 섭취상태에 관한 연구)

  • Kim Mi-Hyun;Bae Yun-Jung;Youn Jee-Young;Chung Yoon-Sok;Sung Chung-Ja
    • Journal of Nutrition and Health
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    • v.38 no.7
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    • pp.570-577
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    • 2005
  • The purpose of this study was to investigate the effect of bone mineral density on life styles, dietary habits and nutrient intakes among the male college students. The subjects were divided into four groups; $Q_1$ (calcaneus BMD < 25 percentile, n = 117), $Q_2$ (25 percentile $\le$ calcaneus BMD < 50 percentile, n = 118), $Q_3$ (50 percentile $\le$ calcaneus BMD < 75 percentile, n = 118) $Q_4$ (calcaneus BMD $\ge$ 75 percentile, n = 116). And they were asked about general characteristics, life style, dietary habit, and nutrient intake using questionnaire and 24-hr recall method. They were measured the bone mineral density of calcaneus using quantitative ultrasound. The average age of the subjects of the study was 23.0 yews and the average height, weight, and BMI were 174.7 cm, 69.0 kg, $22.5 kg/m^2$. The bone mineral density in calcaneus was $0.43 g/cm^2$ in $Q_1,\;0.50 g/cm^2$ in $Q_2,\;0.56 g/cm^2$ in $Q_3$, and $0.69 g/cm^2$ in $Q_4$ (p < 0.001). The results showed that $Q_1$ tended to have irregular exercise compared to the other three groups. Compared with $Q_1$ and $Q_2$, the frequency of skipping breakfast was lower in $Q_3$ and $Q_4$. Also the results showed that the $Q_4$ was significantly more often to drink coffee compared with the other three groups (p < 0.01). The mean daily energy intake was 2210.6 kcal ($88.4\%$ of RDA). The intake of energy, vitamin $B_2$, calcium, and zinc did not meet the Korean RDA. Also the $Q_2$consumed significantly lower intakes of protein (p < 0.05) and plant protein (p < 0.05) compared to the $Q_3$ and $Q_4$. The $Q_1$ and $Q_2$ consumed significantly lower intakes of vitamin $B_2$ (p < 0.01) compared to the $Q_3$ and $Q_4$. In conclusion, male student in lower bone mineral density appeared to have unhealthy life styles and dietary habits in terms of irregular exercise, high frequency of skipping breakfast and lower intakes of protein, vitamin $B_2$ showing a strong need proper education on meal practices and exercise habits for the bone health.

Genetic Insights into Domestication Loci Associated with Awn Development in Rice

  • Ngoc Ha Luong;Sangshetty G. Balkunde;Kyu-Chan Shim;Cheryl Adeva;Hyun-Sook Lee;Hyun-Jung Kim;Sang-Nag Ahn
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.33-33
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    • 2022
  • Rice (Oryza sativa L.) is a widely studied domesticated model plant. Seed awning is an unfavorable trait during rice harvesting and processing. Hence, awn was one of the target characters selected during domestication. However, the genetic mechanisms underlying awn development in rice are not well understood. In this study, we analyzed the genes for awn development using a mapping population derived from a cross between the Korean indica cultivar 'Milyang23' and NIL4/9 (derived from a cross between 'Hwaseong' and O. minuta). Two quantitative trait loci (QTLs), qAwn4 and qAwn9 were mapped on chromosome 4 and 9, respectively, increased awn length in an additive manner. Through comparative sequencing analyses parental lines, LABA1 was determined as the causal gene underlying qAwn4. qAwn9 was mapped to a 199-kb physical region between markers RM24663 and RM24679. Within this interval, 27 annotated genes were identified, and five genes, including a basic leucine zipper transcription factor 76 (OsbZIP76), were considered candidate genes for qAwn9 based on their functional annotations and sequence variations. Haplotype analysis using the candidate genes revealed tropical japonica specific sequence variants in the qAwn9 region, which partly explains the non-detection of qAwn9 in previous studies that used progenies from interspecific crosses. This provides further evidence that OsbZIP76 is possibly a causal gene for qAwn9. The O. minuta qAwn9 allele was identified as a major QTL associated with awn development in rice, providing an important molecular target for basic genetic research and domestication studies. Our results lay the foundation for further cloning of the awn gene underlying qAwn9.

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