• Journal of Genetic Medicine
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• v.7 no.1
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• pp.78-81
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• 2010

Pericentric inversion is not rare in humans and is usually benign. However, pericentric inversion can lead to production of an unbalanced recombinant and might be a cause of repetitive pregnancy loss. Pericentric inversion of chromosome 22 is rare and only a few cases have been reported. We report a case of inv(22)(p13q12) carrier who had history of repetitive pregnancy loss including three spontaneous abortions and one fetal hydrops in which the chromosomal complement was rec(22)dup(22q) inv(22)(p13q12)mat. The maternal inv(22) and fetal rec(22) were confirmed by fluorescence in situ hybridization using region-specific probes (TUPLE1 on 22q11.2 and ARSA on 22q13). Because the identification of inv(22) or rec(22) in conventional karyotyping might be easily overlooked, great attention and additional molecular tests are required for accurate diagnosis of inv(22) and rec(22).

• Korean Journal of Food Science and Technology
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• v.37 no.4
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• pp.597-602
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• 2005

Quality factors of emulsified ginseng drink were determined during storage at various temperatures, and its shelf-life was predicted based on changes in emulsion stability, acidify, viscosity, and yellowness. Viscosity was highly dependent on storage temperature. Emulsion stability changed rapidly during early storage period (1st step), then slowly thereafter (2nd step). $Q_{10}$ values of emulsion stability were 2.50 and 1.38 for 1st and 2nd steps, respectively. Viscosity, acidity, and yellowness showed $Q_{10}$ values of 3.45, 1.77, and 1.99, respectively. Although $Q_{10}$ value of 2 has been generally used to predict shelf stability of food materials, our results suggest adopting same $Q_{10}$ value to predict shelf stability of emulsified ginseng drink is not appropriate.

• Journal of Radiation Protection and Research
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• v.37 no.3
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• pp.116-122
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• 2012

A short-term atmospheric dispersion factor (${\chi}/Q$) is an essential element for radiological dose assessment following a hypothetical accidental releases of light-water nuclear power plants. The U. S. NRC developed PAVAN program to comply with the U. S. NRC's Regulatory Guide 1.145. Meteorological data is an essential element for atmospheric dispersion, and PAVAN uses a joint frequency distribution data, which represents the occurrence probability of wind speed and wind direction for atmospheric stability. Using the meteorological data measured at Kori and Wolsung sites for the last 5 years (from 2006 to 2010), a variety of joint frequency distribution data were prepared to evaluate ${\chi}/Q$ values with different wind speed classifications (U. S. NRC's recommendation and even distribution of occurrence probability) and periods of meteorological data to be analyzed (1 year, 2 year, 3 year, 4 year, 5 year). As a result, it was found that the influence of the wind speed classification on ${\chi}/Q$ values is little, while the influence of the periods of meteorological data to be analyzed is relatively significant, representing more than 1.5 times in the ratio of maximum to minimum values.

• Journal of Auto-vehicle Safety Association
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• v.7 no.4
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• pp.9-15
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• 2015

The relationship between BAC(Blood Alcohol Concentrations) and BrACs(Breath Alcohol Concentrations) and also partition ratio of healthy Korean adult males (96 males) are researched in this paper and its dependency is described according to TBW (total body water), BMI (body mass index), BFM (body fat mass), and PBF (percentage of body fat). Among the above four variables, TBW affects significantly to the partition ratio compared to the other variables. The partition ratio of Korean healthy males showed 1,913 (95 % Confidence Interval (C.I.) from 1,889 to 1,937) for the whole time intervals. However, when Q was averaged after 60 minutes later, its values was 2,011 (95 % C.I. from 1,982 to 2,040). Bland-Altman plots showed the compatibility of measurement methods of multi-gas analyzer, and the biases according to the partition ratios (Q=2,100 and Q=1,913) gave -0.0052 % (95 % CI from -0.0059 to -0.0045%) and -0.0004 % (95 % CI from -0.0011 to +0.0003%), respectively.

• Journal of Auto-vehicle Safety Association
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• v.7 no.3
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• pp.7-13
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• 2015

Occupant protection performance in frontal crashes has been developed and assessed for mainly front seat occupants over many years, and in recent years protection of rear seat occupants has also been extensively discussed. Unlike the front seats, the rear seats are often occupied by children seated in rear-facing or forward - facing child restraint systems, or booster seats. In the ENCAP, child occupant protection assessments using 18-month-old(P1.5) and 3-year-old(P3) test dummies in the rear seat have already been changed to new type of 18-month-old (Q1.5)and 3-year-old(Q3) test dummies. In addition, ENCAP are scheduled with the development and introduction of test dummies of 6-year-old (Q6) and 10.5-year-old children(Q10) starting 2016. In KNCAP, Q6 and Q10 child dummies will be introduced in 2017 as well. Automobile manufacturers need to develop safety performance for new child dummies closely. In this paper, we focused on Q6 and Q10 child dummies sitting in child restraint system. Offset frontal crash tests were conducted using two types of test dummies, Q6 and Q10 child dummies, positioned in the rear seat. Q6 and Q10 were used to compare dummy kinematics in rear seating positions between Q6 behind the driver's seat and Q10 behind the front passenger's seat. The full vehicle sled test results of both dummies were conducted with different restraint systems. It showed that several injury and image data was collected as the result of the full vehicle sled test. Based on the results of these investigations, this paper describes which factor is most important and combination is the best performance when evaluating rear seat occupant protection for Q6 and Q10 child dummies.

• Progress in Medical Physics
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• v.20 no.4
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• pp.317-323
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• 2009

The standard dosimetry systems based on an absorbed dose to water recommend to use a planeparallel chamber for the calibration of such a low-megavoltage electron beam as a nominal energy of 6 MeV. For this energy ranges of an electron beam a cylindrical chamber should not be used for the routinely regular beam calibration, but the feasibility of the temporary use of a cylindrical chamber was studied to give temporary solutions for special situations users meet. The PTW30013 chambers and the electron beam quality of $R_{50}=2.25\;g/cm^2$ were selected for this study. 10 PTW30013 chambers, a cylindrical type of chamber, were calibrated in KFDA, the secondary standards dosimetry laboratories, and given the absorbed dose-to-water calibration factors, respectively. A "temporary" $k_{Q,Q_0}$ for each chamber were calculated using the absorbed dose determined by a cross-calibrated planeparallel chamber, with the result of an average 0.9352 for 10 chambers. This value for PTW30013 chamber was used to determine an absorbed dose to water at the reference depth. The absorbed doses determined by PTW30013 chambers were in an agreement within 2% with that by ROOS chamber. In a certain situation where a cylindrical chamber be used instead of a planeparellel chamber, the value of 0.9352 might be useful to determine an absorbed dose to water in the same beam quality of electron beam as this study.

• Journal of Auto-vehicle Safety Association
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• v.8 no.1
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• pp.31-37
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• 2016

The Child Occupant Safety Assessment was first introduced and carried out by Euro NCAP in 2003, with the goal of ensuring manufacturers to develop safe vehicles for passengers of all ages; the objective was to evaluate the safety and protection offered by different Child Restraint Systems (CRS) in the event of a crash. In 2013, the formerly used P child dummy series was replaced by newer and more biofidelic Q1.5 and Q3 child dummies, representing 1.5 and 3 year old children respectively. The frontal and side impact dynamic performances of the Q1.5 and Q3 were tested within all classes of vehicles assessed by Euro NCAP at the time. As an extension to that initiative, Q6 and Q10 child dummies were later developed representing children of 6 and 10 years old. Since the protection of larger children during vehicle crashes relies greatly on the interaction of vehicle restraint systems such as seat belt and the CRS, instrumented Q6 and Q10 dummies will be used to assess the protection offered in the event of front and side impact crashes. In this paper, we focused on injury criteria of Q6 and Q10 child dummies at 64 kph 40% offset frontal crash test. The whole procedure was designed with DFSS analysis. The full vehicle sled test results of both dummies were conducted with different restraint systems settled through previous sled test. It showed that several injury criteria and image data were collected as the result of the full vehicle sled test. Based on the results of these investigations, this paper describes which factor is most important and combination shows the best performance when evaluating rear seat occupant protection for Q6 and Q10 child dummies.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.1
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• pp.22-29
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• 2016

Serum gamma-glutamyltransferase (GGT) has been widely used as a marker of alcohol intake and liver failure. Recently, the relativity between GGT and various diseases has been identified with growing interest. In this study, we examined relativity between GGT value and risk factors of coronary heart diseases among those with normal GGT value, excluding heavy drinkers. Specifically, we compared the differences based on age and gender. Data from the 2011 KNHNES were used (N=3,619). When the subjects were categorized according to quartile based on the serum GGT levels, there was 10~20, 21~27, 28~38, 39~71 IU/L in men, and 6~12, 13~16, 17~22, 23~42 IU/L in women. The mean of most variables was the highest in the $4^{th}$ quartile (Q4), however age and LDL Cholesterol were the highest in the $2^{nd}$ quartile (Q2) in men. The FRS and 10-year CHD risk was the highest in the $2^{nd}$ quartile in men, and the highest in the $4^{th}$ quartile in women. Increased GGT was correspondingly linked with age in women but age was the highest in GGT in the $2^{nd}$ quartile in men. In the 70's, the highest Q1 and Q2 was in men and the highest Q3 and Q4 in women. Although GGT value was within the normal range, increased GGT showed correlation with various risk factors. The FRS and 10-year CHD risk showed different patterns according to age and gender along with increased GGT value.

• Journal of the Korean Geotechnical Society
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• v.28 no.1
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• pp.29-39
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• 2012

The maximum unit point resistance ($q_{max}$) of rock socketed drilled shafts subjected to axial loads was investigated by a numerical analysis. A 3D Finite Difference Method (FDM) analysis and a Distinct Element Method (DEM) analysis were performed with varying rock elastic modulus (E), discontinuity spacing ($S_j$), discontinuity dip angle ($i_j$), and pile diameter (D). Based on the results of obtained, it was found that the ultimate point resistance ($q_{max}$) increased as rock elastic modulus (E) and rock discontinuity spacing ($S_j$) increased. But, it was found that $q_{max}$ decreased as pile diameter (D) increased. As for the influence of the dip angle of rock discontinuity ($i_j$), it was shown that $q_{max}$ decreased up to 50% of maximum value within the range of $0^{\circ}$ < $i_j$ < $60^{\circ}$ due to the shear failure at rock discontinuities. Furthermore, it was found that if $20^{\circ}{\leq}i_j{\leq}40^{\circ}$, influence of $i_j$ should be taken into account because $q_{max}$ tended to approach a minimum value as $i_j$ approached a value near the friction angle of the discontinuity (${\phi}_j$).

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.13 no.5
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• pp.356-367
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• 2001

A numerical analysis on branch type sparger in drain tank for depressurization is performed to investigate the flow characteristics due to the change of design factor. As the result of this study, sparger\\`s flow resistance coefficient(K) is 3.53 at the present design condition when engineering margin for surface roughness is considered as 20%, and flow ratio into branch pipe ($Q_s/Q_i$) is 0.41. The correlation for calculating flow resistance coefficients as design factor is presented. Flow resistance coefficient is increased as section area ratio of branch pipe for main pipe and outlet nozzle diameter of main pipe decreasing, but the effects of branch angle and inlet flow rate of main pipe are small. As the change rate of ($Q_s/Q_i$)becomes larger, the change rate of flow resistance coefficient increases. The rate of pressure loss has the largest change as section area ratio changing. The condition of maximum flow resistance in sparger is when the outlet nozzle diameter ratio of main pipe ($D_e/D_i$) is 0.167, the section area ratio ($A_s/A_i$) is 0.1 and the branch angle ($\alpha$) is 55^{\circ}$.