• 제목/요약/키워드: Purpose Binding

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공급사슬 내의 파워유형이 정보역량에 미치는 영향: CSV 가치창출 관점 (The Effect of Power Type within Supply Chain on the Information Capability: Perspective of CSV Value Creation)

  • 박광오;장활식;정대현
    • 한국정보시스템학회지:정보시스템연구
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    • 제27권3호
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    • pp.1-24
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    • 2018
  • Purpose The purpose of this study is to attempt to incorporate power theory to evaluate information capability of SCM adopters. Therefore, this study focuses on the relationship of information sharing, partnership quality, and information capacity according to the power intensity of the variables of SCM. and CSV value creation. Design/methodology/approach The questionnaire of SCM builder was conducted and 302 samples were analyzed. Based on the theoretical background of power and information capacity, we set up a structural equation model. Hypothesis testing and statistical analysis were done through AMOS and SPSS. Findings First, it shows that the compensation power among the constrained power has a positive effect on the partnership quality, and the legitimacy power has the positive influence only on the information sharing. Compulsive power, compensation, and legitimacy, which are generally restrictive powers, may reduce the quality of information sharing and partnership, but the results of this study are rather higher. Second, both non-binding power expertise and criterion have a positive effect on information sharing and partnership quality. Third, information sharing has a positive effect on partnership quality. Supporting a number of research results, it is well reflected in SCM attributes where interdependence is important. Fourth, information sharing and partnership quality have a positive effect on information capacity. Information literacy has become an essential element in modern management. Fifth, the enhancement of CSV value creation plays a role of a controlling variable to further strengthen information sharing through non - binding power attribute, expertise and conformity. In addition, the strengthening of CSV value creation has been shown to play a role as a controlling variable to further strengthen the quality of partnership through the non-binding power attribution, but expertise has been rejected.

Prealbumin and Retinol Binding Proteins Are Not Usable for Nutrition Follow-Up in Pediatric Intensive Care Units

  • Tekguc, Hakan;ozel, Deniz;Sanaldi, Huriye;Akbas, Halide;Dursun, Oguz
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제21권4호
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    • pp.321-328
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    • 2018
  • Purpose: Feeding children is a problem in pediatric intensive care units (PICU) and it is difficult to know the correct amount. The purpose of this study is to evaluate if prealbumin or retinol binding proteins (RBP) are effective relative to daily enteral nutrition, without being affected by severity of diseases or infections and can be used to follow up nutritional amount. Methods: This is a prospective observational study that includes 81 patients admitted to PICU in Akdeniz University with estimated duration >72 hours, age between 1 month and 8 years. Daily calorie and protein intake were calculated and prealbumin, RBP and C-reactive protein (CRP) levels were measured on the first, third, fifth and seventh mornings. Results: We find moderate correlation between daily calorie intake and prealbumin levels (r=0.432, p<0.001), RBP levels and daily protein intake (r=0.330, p<0.001). When we investigated the relationship between changes of prealbumin, RBP, CRP, calorie and protein intake during intensive care stay, we found that increase of Prealbumin and RBP levels are explained by decrease of CRP levels (r=-0.546 and -0.645, p<0.001) and not with increase of nourishment. Conclusion: Even adjusted for PRISM3, age and CRP, prealbumin and RBP are correlated with last 24 hours' diet. However, it is not convenient to use as a follow up biomarker because increase of their levels is related with decrease of CRP levels.

확장된 역할기반 접근제어 모델에서 GRBAC을 이용한 프라이버시 제어 (Privacy Control Using GRBAC In An Extended Role-Based Access Control Model)

  • 박종화;김지홍;김동규
    • 한국통신학회논문지
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    • 제30권3C호
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    • pp.167-175
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    • 2005
  • 최근 프라이버시 적용이 IT분야의 가장 중요한 문제의 하나로 대두되고 있다. 프라이버시 보호는 조직의 데이터 처리 시스템에 프라이버시 정책을 적용함으로써 달성될 수 있다. 전통적인 보안 모델은 목적 결합(purpose binding)과 같은 프라이버시의 기본적인 요구사항을 적용하기에 부적절하다. 본 논문은 기존의 보안모델에 통합하여 쉽게 적용할 수 있는 프라이버시 제어 모델을 제안한다. 이를 위하여 기존의 보안모델로 RBAC과 도메인-타입을 적용하여 문맥기반 접근제어를 제공하는 하나의 확장된 역할기반 접근제어 모델이 사용되었고, 프라이버시 제어 모델에서는 프라이버시 선호로 표현되는 목적 결합을 적용하기위해 GRBAC이 사용되었다. 또 이 모델의 응용을 위하여 작은 병원 모델이 고려되었다.

Anti-cardiolipin 항체와 Cardiolipin의 결합에 미치는 $\beta_2$-GP1의 영향 (Effect of $\beta_2$-GP1 on the Binding of Anti-cardiolipin Antibodies to Cardiolipin)

  • 강은영;장영주
    • IMMUNE NETWORK
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    • 제4권3호
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    • pp.161-165
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    • 2004
  • Background: Anti-cardiolipin antibody (Anti-CL Ab) is one of the various antiphospholipid antibodies (Anti-PL Abs) and found in the plasma of patients with systemic lupus erythematosus (SLE), atherosclerosis, and other infectious diseases. While anti-PL Abs found in the sera of patients with infectious diseases bind directly to CL, binding of anti-PL Abs to CL circulating in the sera of patients with autoimmune diseases is mediated by $\beta_2-$glycoprotein 1 ($\beta_2-GP1$). The purpose of this study is to investigate the effect of <$\beta_2-GP1$ on the antigen binding assay of anti-CL Abs present in the sera of patients with atherosclerosis, which has been known as one of autoimmune diseases. Methods: ELISA was performed with sera containing anti-CL Abs from three patients with atherosclerosis in the presence or absence of $\beta_2-GP1$ or FBS. Results: Reactivity of anti-CL Abs to CL was increased in the presence of $\beta_2-GP1$ or FBS in a dose dependent manner. Conclusion: <$\beta_2-GP1$ or FBS could be used as co-factor in CL ELISA with anti-CL Abs present in the sera of patients with atherosclerosis. It is suggested that anti-CL Abs found in atherosclerosis patients are similar in terms of antigen binding property to those circulating in the patients with autoimmune diseases, not to infectious diseases.

Improvement of osteogenic potential of biphasic calcium phosphate bone substitute coated with synthetic cell binding peptide sequences

  • Choi, Hyunmin;Park, Nho-Jae;Jamiyandorj, Otgonbold;Hong, Min-Ho;Oh, Seunghan;Park, Young-Bum;Kim, Sungtae
    • Journal of Periodontal and Implant Science
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    • 제42권5호
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    • pp.166-172
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    • 2012
  • Purpose: The aim of this study was to evaluate the improvement of osteogenic potential of biphasic calcium phosphate (BCP) bone substitute coated with synthetic cell-binding peptide sequences in a standardized rabbit sinus model. Methods: Standardized 6-mm diameter defects were created bilaterally on the maxillary sinus of ten male New Zealand white rabbits, receiving BCP bone substitute coated with synthetic cell binding peptide sequences on one side (experimental group) and BCP bone substitute without coating (control group) on the other side. Histologic and histomorphometric analysis of bone formation was carried out after a healing period of 4 or 8 weeks. Results: Histological analysis revealed signs of new bone formation in both experimental groups (4- and 8-week healing groups) with a statistically significant increase in bone formation in the 4-week healing group compared to the control group. However, no statistically significant difference in bone formation was found between the 8-week healing group and the control group. Conclusions: This study found that BCP bone substitute coated with synthetic cell-binding peptide sequences enhanced osteoinductive potential in a standardized rabbit sinus model and its effectiveness was greater in the 4-week healing group than in the 8-week healing group.

흰쥐 자궁에서의 Cytosolic Progesterone 수용체 측정에 관한 연구 (Determination of Potimal Conditions for Cytosolic Progesterone Receptor Assay in Rat Uterus)

  • 박찬규;박기현;서경;이건수;윤미정;유경자
    • Clinical and Experimental Reproductive Medicine
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    • 제13권2호
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    • pp.187-193
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    • 1986
  • The purpose of this study was to establish optimal conditions for progesterone receptor assay using rat uterus, therby applying this system to understand action mechanism of progesterone in female reproductive organ and to evaluate physiological and pathological conditions in female reproduction. The results obtained were as follows 1. $^3H-R5020$ seemed to be more stable than 3H-progesterone as a ligand. 2. Optimal incubation time for ligand and receptor binding was 4-5 hrs at $4^{\circ}C$. 3. For the separation of bond and free ligand, optimal charcoal incubation time was 20 mins. 4. 2-3 mg cytosolic protein/ml was optimal for the binding of ligand. 5. Endogenous progesterone did not influence binding of ligand and receptor unless endogenous progesterone levels were extremely high as in case of pregnancy. 6. Dissociation rate for progesterone receptor was 1.22 nM. 7. $^3H-R5020$ did not bind to corticoid binding globulin (CBG), suggesting that addition of cortisol is saturate CBG was, not necessary as far as $^3H-R5020$ was used as a radioligand. It is, therefore, considered that this assay system established with these conditions might be used for the research as well as clinical routine purposes.

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Sulpyrin과 Ampicillin의 상호작용(相互作用)에 관(關)한 연구(硏究) (The Studies on the Interaction of Sulpyrin and Ampicillin)

  • 최준식
    • Journal of Pharmaceutical Investigation
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    • 제10권3호
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    • pp.20-26
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    • 1980
  • The purpose of this paper was to study the effect of sulpyrin on the absorption, excretion, metabolism, and protein binding of ampicillin in the small intestine of the rats and rabbits. The results are as follows; The absorption of ampicillin in small intestine of rats was increased by the combination of sulpyrin and ampicillin. The blood level of ampicillin in rabbits was elevated by oral administration of sulpyrin. The bioavailability of ampicillin was increased by simultaneous administration of sulpyrin and ampicillin. The urinary excretion of ampicillin was slightly decreased by combined administration of sulpyrin. The blood level of ampicillin was decreased and the urinary excretion was increased by long term administration of sulpyrin. On the other hand, metabolising enzyme of ampicillin was influenced by long term administration of sulpyrin. Protein binding rate of ampicillin was decreased by combination of sulpyrin as compared with control.

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논의 중인 우주활동 국제규범의 최근 현황과 역할 (Recent Status of International Norms Under Discussion for Outer Space Activities and Its Roles)

  • 정영진
    • 항공우주시스템공학회지
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    • 제8권2호
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    • pp.1-6
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    • 2014
  • Currently outer space become more and more congested and contested, according to the increase of satellites, nations and government consortia that operate satellites, and commercial and academic satellite operators. Therefore, international community, including the United Nations has been making a greater effort to adopt non-legally binding international documents capable of regulating space activities for the purpose of the security, safety and long-term sustainability of space activities. These are a draft International Code of Conduct for Outer Space Activities(ICoC) and UN Group of Governmental Experts on Transparency and Confidence-Building Measures in Outer Space Activities(UNGGE).

양육행동 개념 분석 (A Concept Analysis of the Caretaking Behavior for Children)

  • 김순구
    • Child Health Nursing Research
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    • 제8권4호
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    • pp.414-421
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    • 2002
  • The purpose of this study is to analyze the concept of caretaking behavior for children. This study adopts the methode of Walker and Avant in analysis. Based on the results of the study, the attributes, precedents, and consequences of caretaking behavior for children are follows ; 1. The affirmative attributes of caretaking behavior are affection binding, nutritional guidance, education, caring, protection moral training and acquisition of parents' role. The negative attributes of caretaking behavior are inconsistent moral training, incapability of affection binding and overprotection. 2. The precedent of caretaking behavior are postpartum contact with their babies, cognizance capacity of child-caretaking, economic support, level of preparation for child-caretaking and self-consciousness as parents. 3. The affirmative consequences of caretaking behavior are promotion of child growth and development, formation of maternal-infantile attachment, development of children sociality, satisfaction of parental role and reinforcement of relationship between the members of family. The negative consequences of caretaking behavior are burden and conflict to parental role, children's illness, role conflict and role stress among the members of the family and family breaking up.

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Effect of denture cleansers on Candida albicans biofilm formation over resilient liners

  • Huh, Jung-Bo;Lim, Younghun;Youn, Hye-In;Chang, Brian Myung;Lee, Jeong-Yol;Shin, Sang-Wan
    • The Journal of Advanced Prosthodontics
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    • 제6권2호
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    • pp.109-114
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    • 2014
  • PURPOSE. The purpose of this study was to analyze the effect of denture cleansers on Candida albicans biofilm formation over resilient liners and to evaluate compatibility between resilient liners and denture cleansers. MATERIALS AND METHODS. Acrylic resin (Lucitone 199$^{(R)}$) and 3 resilient liners (COE-SOFT$^{TM}$, GC RELINE$^{TM}$ and SOFRELINER TOUGH TOUGH$^{(R)}$) were incubated in denture cleansers (Polident$^{(R)}$ and Cleadent$^{(R)}$) for 8 hours a day and in unstimulated saliva for 16 hours a day (n=25/gp) for 60 days. Two-way and three-way repeated measures ANOVA were performed to compare the surface roughness (Ra), pH and C. albicans binding level by radioisotope (${\alpha}$=0.05). The statistical significance of the relation between Ra and adhesion was evaluated by correlation analysis. RESULTS. The degree of Ra was significantly decreased in the following order: COE-SOFT$^{TM}$, acrylic resin, GC RELINE$^{TM}$ and SOFRELINER TOUGH$^{(R)}$. The immersion in denture cleansers significantly increased Ra of resilient liners, except for SOFRELINER TOUGH$^{(R)}$ in Cleadent$^{(R)}$. No significant differences in pH curves were observed among groups immersed in distilled water and denture cleansers. The binding levels of C. albicans were significantly decreased in the following order: COE-SOFT$^{TM}$, GC RELINE$^{TM}$, SOFRELINER TOUGH$^{(R)}$, and acrylic resin. The immersion in Cleadent$^{(R)}$ seemed to decrease C. albicans binding level on GC RELINE$^{TM}$ and SOFRELINER TOUGH$^{(R)}$. CONCLUSION. Based on the C. albicans binding levels results, it is not recommended to immerse COE-SOFT$^{TM}$ in denture cleansers, and GC RELINE$^{TM}$ and SOFRELINER TOUGH$^{(R)}$ should be immersed in Cleadent$^{(R)}$.