• Title/Summary/Keyword: Pseudolymphoma

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Radiotherapy in aggressive cutaneous pseudolymphoma: a case report and review of literature

  • Joseph, Deepa;Irukulla, Monica Malik;Ahmed, Syed Fayaz;Valiyaveettil, Deepthi;Akram, Syed
    • Radiation Oncology Journal
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    • v.34 no.1
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    • pp.76-80
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    • 2016
  • Pseudolymphoma is a nonspecific disease characterized by lesions with lymphomatous-appearing but benign accumulation of inflammatory cells. They generally present as small ulcero-nodular lesions confined to skin which often respond to local therapies. We describe an unusual presentation of an extensive and locally aggressive cutaneous pseudolymphoma in a 21-year-old male patient who presented with extensive cutaneous eruptions gradually progressing over 6 years to involve the entire circumference of his left arm. Magnetic resonance imaging scans of his left arm showed a lesion deeply infiltrating into the soft tissue reaching up to the humerus with intense periosteal reaction. He was successfully treated with radiotherapy after many failed attempts with surgery and chemotherapy.

Hepatic Pseudolymphoma Mimicking a Hypervascular Tumor: A Case Report (과혈관성 종양으로 오인된 간의 가성림프종: 증례보고)

  • Im, Bora;Jang, Suk Ki;Yeon, Jae Woo;Paik, So Ya;Park, Sang Jong;Kim, Hyuk Jung
    • Journal of the Korean Society of Radiology
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    • v.79 no.6
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    • pp.348-353
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    • 2018
  • Hepatic pseudolymphoma is a rare benign liver mass that is characterized by proliferation of non-neoplastic lymphocytes extranodally. To the best of our knowledge, only 46 cases have been reported in the English literature. We described the case of a 75-year-old woman with hepatic pseudolymphoma mimicking a hypervascular tumor. After the histological confirmation of the rectal neuroendocrine tumor, CT scan revealed a 1.0 cm-sized, poorly-defined and low-density nodule in the liver. On MRI, the hepatic nodule showed an arterial enhancement and a low-signal intensity on the hepatobiliary phase. On diffusion-weighted imaging, the hepatic nodule showed a high signal intensity on a high b-value. On fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT, it revealed a high standardized uptake value nodule. The US showed the hypoechoic nodule and the US-guided biopsy confirmed the hepatic pseudolymphoma.

A Case of Pseudolymphomatous IgG4-Related Disease Involving the Maxilla (상악골 침범으로 나타난 거짓림프종양 IgG4 연관병증 1예)

  • Kim, Min-Jung;Bae, Seung-Il;Kim, Hoon-Tae;Hong, Young-Hoon;Kim, Hyun-Je;Lee, Choong-Ki;Gu, Mi Jin
    • Journal of Yeungnam Medical Science
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    • v.30 no.2
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    • pp.128-131
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    • 2013
  • Immunoglobulin G4 (IgG4)-related disease is an inflammatory condition characterized by IgG4 positive plasma cell infiltration. It can affect any organ in the body and mainly involves the pancreas, liver, biliary tracts, orbits, salivary glands and lymph nodes. It can manifest as an inflammatory pseudotumor. Pseudolymphoma as an inflammatory pseudotumor is a group of benign tumors that exhibit histological and clinical features suggestive of malignant lymphoma. Studies on IgG4-related disease are rarely reported, and no case of the disease that involved the maxillary bone and adjacent soft tissue, except for the skin, has been reported. Therefore, we report herein a case of pseudolymphomatous IgG4-related disease that involved the maxilla, with a literature review.

Lymphocytoma cutis: diagnostic enigma for the maxillofacial surgeon

  • Kale, Tejraj P.;Singh, Arjun Gurmeet;Shah, Pushpak
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.42 no.6
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    • pp.379-382
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    • 2016
  • Cutaneous lymphoid hyperplasia (CLH) is a cutaneous pseudolymphoma with a worldwide distribution, equally affecting all races and ethnic groups. Due to its vast array of characteristics, it is most often missed in the differential diagnosis of firm to soft lumps on the head and neck. A systematic approach to the workup and diagnosis along with treatment of such lesions is discussed in this article. A 20-year-old Asian Indian female presented to our Oral and Maxillofacial unit with a lump on the left side of her forehead for 1 month. Local examination revealed a $2.5{\times}3.0cm^2$, well circumscribed swelling over the left para median region that was firm to doughy and non-tender. There was no other significant finding on general examination. Excisional biopsy of the lesion was performed, followed by histopathologic processing. The general etiology, pathogenesis, clinical presentation, differential diagnosis, clinical course, prognosis, treatment, and prevention have been discussed in line with the recent modalities of diagnosis and treatment of CLH. Due to the overlapping clinical and histological characteristics of CLH with many other lesions, it is important to consider this lesion in the differential diagnosis of cutaneous lesions.

Multifocal nodular lymphoid hyperplasia of the lung

  • Lee, Gil Tae;Kim, Eun Kyoung;Cho, Eirie;Lee, Seung-Sook;Kim, Seo Yun;Kim, Cheol Hyeon;Kim, Hye-Ryoun
    • Journal of Yeungnam Medical Science
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    • v.34 no.1
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    • pp.84-87
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    • 2017
  • Nodular lymphoid hyperplasia (NLH) is a benign lymphoproliferative disease that can affect the lung. Because of its rarity, little is known about the etiology and natural history of NLH. Most cases are usually asymptomatic and found incidentally on imaging studies. Imaging finding of NLH has shown most commonly as a solitary lesion, although multifocal pulmonary nodules may be seen. Surgical resection has proved curative in the cases previously described. We report a rare case of NLH in a 55 year-old man who presented with bilateral multiple pulmonary nodules on chest radiography. Open biopsy was performed from the upper and lower lobe of the left lung. The lesions were pathologically diagnosed as pulmonary NLH. Multifocal residual nodules in both lungs remain stable without spontaneous regression during the 3 years of follow-up.

Pulmonary Nodular Lymphoid Hyperplasia (폐 결절성 림프구양 증식증)

  • Koo, Hyeon-Kyoung;Kim, Seo-Yun;Park, Sung-Soo;Lee, Yeon-Joo;Lee, Ji-Yeon;Chung, Jin-Haeng;Lee, Jae-Ho;Lee, Choon-Taek;Yoon, Ho-Il
    • Tuberculosis and Respiratory Diseases
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    • v.69 no.3
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    • pp.212-216
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    • 2010
  • Nodular lymphoid hyperplasia is a very rare benign disease and usually shows consolidation on chest X-ray with symptoms of pneumonia due to the proliferation of lymphoid cells in the lung parenchyma. It is common for patients to be diagnosed with pneumonia and treated with antibiotics, but patients often enter a cycle of repeated improvement, followed by aggravation of symptoms. At this point, surgical diagnostic tools are considered in order to differentiate between malignant disease and interstitial lung disease. Here, we report 2 cases of patients with nodular lymphoid hyperplasia and review the associated references.

Cases of the Pulmonary Malignant Lymphoma of the Bronchus-Associated Lymphoid Tissue(BALT) (원발성 기관지 연관 림프조직(BALT) 림프종 3예)

  • Lee, Sang-Min;Yoon, Ho-Il;Choi, Seung-Ho;HwengBo, Bin;Yoo, Chul-Gyu;Lee, Choon-Teek;Kim, Young-Whan;Han, Sung-Koo;Shim, Young-Soo
    • Tuberculosis and Respiratory Diseases
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    • v.47 no.5
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    • pp.681-690
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    • 1999
  • The primary mucosa-associated lymphoid tissue(MALT) lymphoma of the lung is a rare low grade B cell-lymphoma arising from bronchus-associated lymphoid tissue(BALT) which had been regarded as pseudolymphoma. It has the characteristic histologic findings with monoclonal B cells of centrocyte-like lymphoid cells and a lymphoepithelial lesion. Clinically it shows an indolent clinical course and much more favorable prognosis than lymphoma of other site. We report 3 cases of the pulmonary malignant lymphoma of BALT, which was confirmed by lung biopsy, immunohistochemistry and PCR assay.

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