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Hepatic Pseudolymphoma Mimicking a Hypervascular Tumor: A Case Report

과혈관성 종양으로 오인된 간의 가성림프종: 증례보고

  • Im, Bora (Department of Radiology, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Jang, Suk Ki (Department of Radiology, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Yeon, Jae Woo (Department of Radiology, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Paik, So Ya (Department of Pathology, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Park, Sang Jong (Department of Internal Medicine, Daejin Medical Center Bundang Jesaeng General Hospital) ;
  • Kim, Hyuk Jung (Department of Radiology, Daejin Medical Center Bundang Jesaeng General Hospital)
  • 임보라 (분당제생병원 영상의학과) ;
  • 장석기 (분당제생병원 영상의학과) ;
  • 연재우 (분당제생병원 영상의학과) ;
  • 백소야 (분당제생병원 병리과) ;
  • 박상종 (분당제생병원 내과) ;
  • 김혁중 (분당제생병원 영상의학과)
  • Received : 2018.04.02
  • Accepted : 2018.06.06
  • Published : 2018.12.01

Abstract

Hepatic pseudolymphoma is a rare benign liver mass that is characterized by proliferation of non-neoplastic lymphocytes extranodally. To the best of our knowledge, only 46 cases have been reported in the English literature. We described the case of a 75-year-old woman with hepatic pseudolymphoma mimicking a hypervascular tumor. After the histological confirmation of the rectal neuroendocrine tumor, CT scan revealed a 1.0 cm-sized, poorly-defined and low-density nodule in the liver. On MRI, the hepatic nodule showed an arterial enhancement and a low-signal intensity on the hepatobiliary phase. On diffusion-weighted imaging, the hepatic nodule showed a high signal intensity on a high b-value. On fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT, it revealed a high standardized uptake value nodule. The US showed the hypoechoic nodule and the US-guided biopsy confirmed the hepatic pseudolymphoma.

간의 가성 림프종은 비종양성 림프구의 절 외 과다증식에 의해 형성되는 드문 양성 종양이다. 검색한 바에 따르면 현재까지 영문으로 46예가 보고되었다. 우리는 75세 여자환자에서 과혈관성 종양으로 오인된 간의 가성 림프종 증례를 보고하고자 한다. 조직검사상 직장의 신경내분비 암종이 진단된 후 시행한 조영증강 전산화단층촬영에서 1.0 cm 크기의 경계가 불분명하고 낮은 감쇄를 보이는 결절이 간에 관찰되었다. 자기공명영상에서는 동맥 조영기에 조영 증강을 보이고, 20분 지연기 조영 영상에서 저신호 강도를 보이며, 확산강조영상에서 고신호 강도를 보였다. Fluorodeoxyglucose (이하 FDG) positron emission tomography (PET)/CT에서는 FDG의 섭취 증가를 보였다. 초음파에서는 저에코성 병변으로 관찰되었고, 초음파 유도 하 조직검사를 통하여 간의 가성 림프종으로 확진 되었다.

Keywords

References

  1. Yoshida K, Kobayashi S, Matsui O, Gabata T, Sanada J, Koda W, et al. Hepatic pseudolymphoma: imaging-pathologic correlation with special reference to hemodynamic analysis. Abdom Imaging 2013;38:1277-1285 https://doi.org/10.1007/s00261-013-0016-6
  2. Yang CT, Liu KL, Lin MC, Yuan RH. Pseudolymphoma of the liver: report of a case and review of the literature. Asian J Surg 2017;40:74-80 https://doi.org/10.1016/j.asjsur.2013.07.013
  3. Machida T, Takahashi T, Itoh T, Hirayama M, Morita T, Horita S. Reactive lymphoid hyperplasia of the liver: a case report and review of literature. World J Gastroenterol 2007;13:5403-5407 https://doi.org/10.3748/wjg.v13.i40.5403
  4. Matsumoto N, Ogawa M, Kawabata M, Tohne R, Hiroi Y, Furuta T, et al. Pseudolymphoma of the liver: sonographic findings and review of the literature. J Clin Ultrasound 2007;35:284-288 https://doi.org/10.1002/jcu.20244
  5. Snover DC, Filipovich AH, Dehner LP, Krivit W. 'Pseudolymphoma'. A case associated with primary immunodeficiency disease and polyglandular failure syndrome. Arch Pathol Lab Med 1981;105:46-49
  6. Okada T, Mibayashi H, Hasatani K, Hayashi Y, Tsuji S, Kaneko Y, et al. Pseudolymphoma of the liver associated with primary biliary cirrhosis: a case report and review of literature. World J Gastroenterol 2009;15:4587-4592 https://doi.org/10.3748/wjg.15.4587
  7. Taguchi K, Kuroda S, Kobayashi T, Tashiro H, Ishiyama K, Ide K, et al. Pseudolymphoma of the liver: a case report and literature review. Surg Case Rep 2015;1:107 https://doi.org/10.1186/s40792-015-0110-9
  8. Moon WS, Choi KH. Reactive lymphoid hyperplasia of the liver. Clin Mol Hepatol 2013;19:87-91 https://doi.org/10.3350/cmh.2013.19.1.87
  9. D'Onofrio M, Rozzanigo U, Masinielli BM, Caffarri S, Zogno A, Malago R, et al. Hypoechoic focal liver lesions: characterization with contrast-enhanced ultrasonography. J Clin Ultrasound 2005;33:164-172 https://doi.org/10.1002/jcu.20111
  10. Dorffel Y, Wermke W. Neuroendocrine tumors: characterization with contrast-enhanced ultrasonography. Ultraschall Med 2008;29:506-514 https://doi.org/10.1055/s-2008-1027555