• Title/Summary/Keyword: Prospective Studies

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Evolving Direction of BPM for SOA-based e-Business Enhancement (SOA 기반의 e-비즈니스 고도화를 위한 BPM의 발전과제)

  • Lee, Yong-Han;Kim, Hoon-Tae
    • The Journal of Society for e-Business Studies
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    • v.12 no.2
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    • pp.233-247
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    • 2007
  • In order for companies to survive rapidly changing business environment, it is expected that the activities in an enterprise must be reorganized around business processes; the information infrastructures are based on Web Services; and information systems are re-built around the BPMS (Business Process Management System). In this research we suggest major directions of e-business enhancement especially based on SOA(Service Oriented Architecture). Then we investigate the correlation between BPM functionalities and e-business technologies, and suggest priorities among the evolving directions of BPM functionalities via an intensive expert survey. The results of this study can be used by BPM solution vendors, prospective buyers and IT policy makers.

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Consideration in treatment decisions for refractory Mycoplasma pneumoniae pneumonia

  • Cho, Hye-Kyung
    • Clinical and Experimental Pediatrics
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    • v.64 no.9
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    • pp.459-467
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    • 2021
  • Mycoplasma pneumoniae (MP) is the most common cause of childhood bacterial pneumonia. Although macrolide is known to be effective as a first-line therapy, the proportion of macrolide resistance in MP pneumonia has strikingly increased during recent 2 decades in East Asia. This is challenging to physicians since they have to decide more often whether to use secondary treatment. Diagnostic methods to detect macrolide-resistance of MP are currently not available in Korean hospitals. Even in the diagnosis of MP infection, both serologic and molecular test have limitation: inability to differentiate current illness from carriage or asymptomatic infection. Combining these 2 diagnostic methods and excluding infection caused by other respiratory pathogens allow a more reliable diagnosis. This effort is even more demanding in recent years to keep children from unnecessary exposure to secondary antibiotics. Although several observational studies have reported that tetracycline and fluoroquinolone, which are considered in the treatment of refractory MP pneumonia, have efficacy of shortening the duration of fever and respiratory symptoms, those findings need to be proven by well-designed prospective studies. The use of tetracycline and fluoroquinolone in children is generally tolerable, as supported by many observational data. However, since concerns about side effects still remain, careful consideration about benefits and risks is needed to decide their use.

Anesthetic efficacy of Gow-Gates versus inferior alveolar nerve block for irreversible pulpitis: a systematic quantitative review

  • Sarfaraz, Ifrah;Pascoal, Selma;Macedo, Jose Paulo;Salgado, Abel;Rasheed, Dil;Pereira, Jorge
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.21 no.4
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    • pp.269-282
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    • 2021
  • This review aimed to assess and compare the outcomes of the anesthetic efficacy of inferior alveolar nerve block (IANB) and Gow-Gates mandibular nerve block (GGMNB) in patients with symptomatic irreversible pulpitis. A descriptive systematic review of quantitative research was conducted wherein the "Preferred Reporting Items for Systematic Reviews (PRISMA)" was adopted, and the Problem/Patient/Population, Intervention/Indicator, Comparison, Outcome (PICO) criteria were used to structure the research question. A literature search was performed using PubMed/Medline, Cochrane Library, Google Scholar, and Ovid. Selection criteria were applied for populations over nine years of age, of either sex, with irreversible pulpitis, and articles published in English regarding conventional IANB or IANB and Gow-Gates techniques between 2009 and 2019. Prospective randomized clinical trials or randomized controlled trials were included in the review, in which anesthetic efficacy or success was measured. After screening, four articles were included. Three studies were randomized clinical trials, and two were randomized controlled trials. The validity and reliability of the individual studies were examined. There was evidence of the higher efficacy of the GGMNB technique than that of the IANB technique. However, both techniques can be mastered through training.

A Critical Look at the Prague Rules: Rules on the Efficient Conduct of Proceedings in International Arbitration

  • Jun, Jung Won
    • Journal of Arbitration Studies
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    • v.29 no.3
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    • pp.53-74
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    • 2019
  • Due to the increasingly popular dissatisfaction regarding the inefficiency of arbitral proceedings, the Rules on the Efficient Conduct of Proceedings in International Arbitration, also known as the Prague Rules, was launched in December 2018, with the purpose of increasing the efficiency of arbitral proceedings by encouraging arbitral tribunals to take a more proactive role in conducting their procedures. In this article, the provisions of the Prague Rules are examined, in light of those of the IBA Rules on the Taking of Evidence in International Arbitration, in order to determine the efficacy of the Prague Rules on enhancing the efficiency in arbitral proceedings. The author concludes that more specific and detailed provisions, with respect to what the Rules means by such a "proactive arbitral tribunal," should have been explicitly included in light of the Rules' repeated emphasis on such. Also, the prospective outlook on the Prague Rules is not entirely clear as the text does not appear to fill in the gaps in other widely utilized arbitration rules or to supplement them in a satisfying way. However, given that only a short amount of time has passed since the launch late last year, only time will reveal how effective the Prague Rules will be in increasing the efficiency of arbitral proceedings, in accordance with its intended effect.

Implications of 3-Dimensional Printed Spinal Implants on the Outcomes in Spine Surgery

  • Fiani, Brian;Newhouse, Alexander;Cathel, Alessandra;Sarhadi, Kasra;Soula, Marisol
    • Journal of Korean Neurosurgical Society
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    • v.64 no.4
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    • pp.495-504
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    • 2021
  • Three-dimensional printing (3DP) applications possess substantial versatility within surgical applications, such as complex reconstructive surgeries and for the use of surgical resection guides. The capability of constructing an implant from a series of radiographic images to provide personalized anatomical fit is what makes 3D printed implants most appealing to surgeons. Our objective is to describe the process of integration of 3DP implants into the operating room for spinal surgery, summarize the outcomes of using 3DP implants in spinal surgery, and discuss the limitations and safety concerns during pre-operative consideration. 3DP allows for customized, light weight, and geometrically complex functional implants in spinal surgery in cases of decompression, tumor, and fusion. However, there are limitations such as the cost of the technology which is prohibitive to many hospitals. The novelty of this approach implies that the quantity of longitudinal studies is limited and our understanding of how the human body responds long term to these implants is still unclear. Although it has given surgeons the ability to improve outcomes, surgical strategies, and patient recovery, there is a need for prospective studies to follow the safety and efficacy of the usage of 3D printed implants in spine surgery.

Associations between obstructive sleep apnea and painful temporomandibular disorder: a systematic review

  • Kang, Jeong-Hyun;Lee, Jeong Keun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.48 no.5
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    • pp.259-266
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    • 2022
  • The relationship between obstructive sleep apnea (OSA) and diverse types of pain conditions have been proposed. However, no consensus on the relationship between OSA and painful temporomandibular disorders (TMDs) has been established. Therefore, this systematic review has been conducted to review the existing literatures and provide comprehensive synthesis of such literatures about OSA and painful TMDs using the evidence-based methodology. A literature search was conducted using two electronic databases, Scopus, and PubMed. Risk of bias was assessed using the risk-of-bias assessment tool for non-randomized study version 2.0. A total of 158 articles were screened from the initial search and eventually, 5 articles were included in this systematic review. One study adopted both the longitudinal prospective cohort and case-control designs and other 4 articles adopted the cross-sectional design. Two studies employed polysomnography (PSG) for the diagnosis of OSA and mentioned the results from the PSG. All cross-sectional studies demonstrated higher OSA prevalence among patients with TMD, and one cohort study suggested OSA as a risk factor for TMD. OSA appears to have potential influences on the development of TMD; however, the role of TMD in the development of OSA remains to be unknown owing to the lack of high-quality evidences.

A Prediction Model for studying the Impact of Separated Families on Students using Decision Tree

  • Ourida Ben boubaker;Ines Hosni;Hala Elhadidy
    • International Journal of Computer Science & Network Security
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    • v.23 no.4
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    • pp.79-84
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    • 2023
  • Social studies show that the number of separated families have lately increased due to different reasons. Despite the causes for family rift, many problems are resulted which affected the children physically and psychologically. This effect may cause them fail in their life especially at school. This paper focuses on the negative reaction of the parents' separation with other factors from the computer science prospective. Since the artificial intelligent field is the most common widespread in computer science, a predictive model is built to predict if a specific child whose parents separated, may complete the school successfully or fail to continue his education. This will be done using Decision Tree that have proved their effectiveness on the predication applications. As an experiment, a sample of individuals is randomly chosen and applied on our prediction model. As a result, this model shows that the separation may cause the child success at school if other factors are satisfied; the intelligent of the guardian, the relation between the parents after the separation, his age at the separation time, etc.

Clinical Utility of Portal Venous Circulating Tumor Cells in Pancreatic Cancer (췌장암에서 간 문맥 순환 종양 세포의 임상적인 유용성)

  • Seung Bae Yoon;Sung Woo Ko
    • Journal of Digestive Cancer Research
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    • v.11 no.1
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    • pp.21-29
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    • 2023
  • Despite recent advancements in the diagnosis and treatment of pancreatic cancer, clinical results remain dismal. Furthermore, there are no reliable biomarkers or alternatives beyond carbohydrate antigen 19-9. Circulating tumor cells (CTCs) may be a potential biomarker, but their therapeutic application is constrained by their rarity in peripheral venous blood. Theoretically, the portal vein can be a more appropriate location for the detection of CTCs, because the first venous drainage of pancreatic cancer is portal circulation. According to several studies, the number and detection rate of CTCs may be higher in the portal blood than in the peripheral blood. CTC counts in the portal blood are strongly correlated with several prognostic parameters such as hepatic metastasis, recurrence after surgery, and survival. The phenotypic and genotypic properties analyzed in the captured portal CTCs can assist us to comprehend tumor heterogeneity and predicting the prognosis of pancreatic cancer. The investigations to date are limited by small sample sizes and varied CTC detection techniques. Therefore, a large number of prospective studies are required to confirm portal CTCs as a valid biomarker in pancreatic cancer.

The link between Helicobacter pylori infection and gallbladder and biliary tract diseases: A review

  • Klay Puay Khim Lim;Aaron Jia Loong Lee;Xiuting Jiang;Thomas Zheng Jie Teng;Vishal G. Shelat
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.3
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    • pp.241-250
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    • 2023
  • Helicobacter pylori is a gram-negative pathogen commonly associated with peptic ulcer disease and gastric cancer. H. pylori infection has also been reported in cholelithiasis, cholecystitis, gallbladder polyps, and biliary tract cancers. However, the association between H. pylori and gallbladder and biliary tract pathologies remains unclear due to the paucity of literature. In response to the current literature gap, we aim to review and provide an updated summary of the association between H. pylori with gallbladder and biliary tract diseases and its impact on their clinical management. Relevant peer-reviewed studies were retrieved from Medline, PubMed, Embase, and Cochrane databases. We found that H. pylori infection was associated with cholelithiasis, chronic cholecystitis, biliary tract cancer, primary sclerosing cholangitis, and primary biliary cholangitis but not with gallbladder polyps. While causal links have been reported, prospective longitudinal studies are required to conclude the association between H. pylori and gallbladder pathologies. Clinicians should be aware of the implications that H. pylori infection has on the management of these diseases.

Cubes with lattics-point vertices (수격자점을 꼭지점으로 갖는 정육면체의 개수 -지오보드의 활용-)

  • 이만근
    • Journal of Educational Research in Mathematics
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    • v.8 no.1
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    • pp.137-144
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    • 1998
  • A common geoboard puzzel serves as the point of departure for an investigation that lends itself to whole-group discussion with a class of prospective secondary school teachers. Students are provided with opportunities to devise and carry out problem-solving strategies (called 'heuristics' by Polya); exploit inerrelationships among geometry, arithmetic and algebra; formulate generalizations and conjectures; plan and execute an computational project; construct mathematical arguments to establish theorems; and find counter-examples to dispose of a false conjecture. In recent tears, Eugene F. Krause wrote two papers having the same title except for the numeral In that papers he arrives at an theorem about the sizes of squares with lattice point vertices in the coordinate plane, In this paper we follow a different path genearlization to coordinate 3-space

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