• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.243-248
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• 2013

Background: Associations between elevated C-reactive protein (CRP) and cancer risk have been reported for many years, but the results from prospective cohort studies remains controversial. A meta-analysis of prospective cohort studies was therefore conducted to address this issue. Methods: Eligible studies were identified by searching the PubMed and EMBASE up to October 2012. Pooled hazard ratios (HR) was calculated by using random effects model. Results: Eleven prospective cohort studies involving a total of 194,796 participants and 11,459 cancer cases were included in this meta-analysis. The pooled HR per natural log unit change in CRP was 1.105 (95% confidence interval (CI): 1.033-1.178) for all-cancer, 1.308 (95% CI: 1.097-1.519) for lung cancer, 1.040 (95% CI: 0.910-1.170) for breast cancer, 1.063 (95% CI: 0.965-1.161) for prostate cancer, and 1.055 (95% CI: 0.925-1.184) for colorectal cancer. Dose-response analysis showed that the exponentiated linear trend for a change of one natural log unit in CRP was 1.012 (95% CI: 1.006-1.018) for all-cancer. No evidence of publication bias was observed. Conclusions: The results of this meta-analysis showed that the elevated levels of CRP are associated with an increased risk of all-cancer, lung cancer, and possibly breast, prostate and colorectal cancer. The result supports a role of chronic inflammation in carcinogenesis. Further research effort should be performed to identify whether CRP, as a marker of inflammation, has a direct role in carcinogenesis.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.2323-2328
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• 2014

Background: Epidemiological findings are controversial relating to the relationship between dietary folate intake and the risk of breast cancer. We therefore conducted a meta-analysis of prospective cohort studies to clarify this association. Materials and Methods: PUBMED, EMBASE, and MEDLINE databases were searched for all relevant literature published in English from January 1, 1966 to August 2013. Summary relative risk (RR) and 95% confidence intervals (CIs) were calculated using a fixed or random effects model. Results: Dietary folate intake was not significantly associated with the risk of breast cancer. The combined RR with 95%CI for the highest vs. lowest category dietary intake of folate [fifteen studies; 1,836,566 participants and 24,083 patients with breast cancer] was 0.98 (0.90-1.05). Among subgroup analysis by menstrual status, hormonal status and the consumption of alcohol, methionine and vitamin B12, no significant association was observed for the dietary intake of folate and the risk of breast cancer. Dose-response analysis showed that a 220 ${\mu}g/day$ increment in dietary folate intake was not associated with the risk of breast cancer. Conclusions: Our findings indicate that dietary folate intake has no significant effect on the risk of breast cancer.

• 디지털산업정보학회논문지
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• 제20권2호
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• pp.91-108
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• 2024

The purpose of this study is to investigate factors influencing the prospects of living labs among Millennials and Generation Z and to provide policy suggestions. This study proposed a comprehensive framework to investigate the influence of citizen awareness, perceived definition, willingness to participate, the role of local government. and expected satisfaction. This study employed an online survey conducted by a well-known research organization. Factor and regression analysis were utilized for data analysus. The results of this study indicate that the effects of citizen awareness, willingness to participate, the role of local government, and expected satisfaction on the prospects for living labs were significant for Millennials, whereas the effects of perceived definition and expected satisfaction on the prospects for living labs were significant for Generation Z. This study suggests the importance of developing better policies to create prospective living labs for real-world environments. This includes preparing policies for the development of future-oriented living labs, establising innovative living labs for practical applications, and designining future-realy living labs to address real-world challenges.

• 아동학회지
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• 제23권3호
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• pp.1-15
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• 2002

The subjects of this study were 4th to 6th grade children and instruments were the Teenage Inventory of Social Skills, the Internal-External Control Scale, the Self-Esteem Scale, and the Peer Relations Questionnaire. In the concurrent study, children lower in social skills and in self-esteem and external in locus of control reported more bullying and victimization. Children higher in social skills and in self-esteem and internal in locus of control reported more prosocial behavior. In the prospective study, children lower in social skills were more involved in bullying and victimization. Children higher in social skills reported more prosocial behavior. The effects of locus of control and self-esteem on peer relations diminished over time. However, social skills had a significant influence on bullying, victimization and prosocial behavior up to two years later. Children lower in psychosocial development were more vulnerable to peer victimization.

• 한국전자통신학회논문지
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• 제18권4호
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• pp.649-660
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• 2023

본 연구의 목적은 조직원의 정보보안 준수 활동에 부정적 영향을 주는 조직 환경 조건과 이에 따른 개인의 인식 및 가치 차이의 복합적 영향을 확인하는 것이다. 세부적으로, 연구는 조직 내 성과를 강조하는 경쟁적 심리 분위기가 보안 준수 의도에 부정적 영향을 미치는 과정 중, 정보보안 관련 예측 및 억제 걱정, 그리고 가치차이가 역할을 할 것으로 판단하였으며, 관련 매커니즘을 확인하고자 하였다. 본 연구는 387건의 정보보안 규정을 보유한 조직의 근로자로부터 설문을 확보하였으며, AMOS 22.0과 Process 3.1 패키지를 통해 제기한 연구가설을 검증하였다. 분석 결과, 경쟁적 심리 분위기가 개인의 정보보안에 대한 예측 걱정과 억제 걱정을 높여 보안 준수 의도에 부정적 영향을 주는 것을 확인하였다. 또한, 정보보안 관련 가치 차이가 예측 및 억제 걱정과 상호작용 효과를 가져 준수 의도에 부정적 영향을 주는 것을 확인하였다. 본 연구는 조직 내부의 정보보안 목표 달성을 위해 조직원에게 제공해야 할 정보 및 가치 유형을 제시한 측면에서 실무적 시사점을 가지며, 걱정과 가치 차이의 복합적 영향을 정보보안에 적용한 측면에서 학술적 시사점을 가진다.

• 한국가정과교육학회지
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• 제29권1호
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• pp.57-70
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• 2017

본 연구는 예비 가정과 교사의 교수내용지식(PCK)과 교수 효능감 수준을 알아보고 이들 간의 관계를 확인하고, 예비 가정과 교사의 일반적인 특성에 따른 PCK와 교수 효능감 수준을 알아보는 것을 목적으로 하였다. 이를 위하여 전국의 대학교 사범대학의 가정교육과 학생 또는 교육대학원의 가정교육전공 학생 202명을 대상으로 설문조사를 실시하였다. 그 결과 대체로 예비 가정과 교사들의 PCK에 대한 자기지각과 교수 효능감은 높지 않은 편으로 나타났다. PCK 하위범주 중에서는 내용지식의 평균값이 가장 높았고, 표현지식과 환경상황지식이 가장 낮은 값을 보였다. 또한 표현 지식과 내용 지식이 많을수록 가정교과의 교수 자기 효능감이 높은 것으로 나타났으며, 표현지식과 환경상황지식이 높을수록 교수 결과에 대한 기대감이 높은 것으로 나타났다. 학생 지식도 자기 효능감의 두 변수들과 높은 상관을 보였다. 또한 예비교사들의 학년, 교직진로선택 여부, 수강한 기본이수과목수에 따라 PCK와 교수 효능감에서 유의한 차이를 보였다. 2학년의 PCK와 교수 효능감이 가장 높았고, 3, 4학년으로 갈수록 오히려 PCK와 교수 효능감이 떨어지는 것으로 나타났다. 또한 교직을 고려하지 않을수록 PCK와 교수 효능감이 높았으며, 수강한 기본이수과목수는 PCK와 교수 효능감에 부적 영향을 보였다. 예비 가정과 교사들의 PCK에 대한 자기지각과 교수 효능감은 높지 않은 편으로 나타났다. 본 연구는 교사양성기관에서의 학생들의 교수 효능감을 증진할 수 있는 교육과정과 교사로서의 진로를 선택할 경우 진로를 위하여 준비할 수 있는 지원 등이 마련되어야 하며, 교원양성 교육과정 중 예비교사들에게 수업실연과 교육 실습의 기회가 충분히 주어지도록 하는 것이 중요함을 제언하고 있다.

• 대한한의학회지
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• 제31권2호
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• pp.78-90
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• 2010

Objective: The aim of this study was to review case reports about adverse events of acupuncture or moxibustion treatments in Korea. Methods: Electronic literature searches were performed for adverse events of acupuncture or moxibustion treatments in Korea up to October 2009. Results: Sixteen case reports or case series were retrieved in total. Among them, 10 were reporting about acupuncture, 5 about pharmaco-acupuncture (3 bee venom acupuncture and 2 others), and 1 was reporting about moxibustion treatment. The incidence of adverse effects couldn't be proven due to the lack of prospective studies. Conclusion: Acupuncture treatment seems to be one of the safer forms of medical interventions, when performed by skilled Korean medical doctors. However, prospective studies are necessary to reach conclusions about safety. In addition, a system for collecting and managing adverse effects of Korean medical interventions as well as a reeducation system for clinicians is needed.

• 간호행정학회지
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• 제22권5호
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• pp.415-423
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• 2016

Purpose: The purpose of this research was to provide patients with safe preoperative preparatory procedures by removing any risk factors from the preparatory procedures by using failure mode and effects analysis, which is a prospective risk-managing tool. Methods: This was a research design in which before and after conditions of a single group were studied, Failure mode and effects analysis were applied for the preparatory procedures done before operations. Results: The preparation omission rate before the operation decreased from 2.70% to 0.04%, and operation cancellation rate decreased from 0.48% to 0.08%. Conclusion: Failure mode and effects analysis which remove any risk factors for patients in advance of the operation is effective in preventing any negligent accidents.

• Journal of Korean Neurosurgical Society
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• 제30권2호
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• pp.173-179
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• 2001

Purpose : To assess therapeutic effects of percutaneous polymethylmethacrylate(PMMA) vertebroplasty on the pain caused by osteoporotic thoracic and lumbar vertebral body compression fractures in a large scale of a prospective clinical design, and to determine clinical factors influencing its therapeutic effects. Methods : A prospective clinical study was carried out in 349 vertebral levels of 159 patients between April 1998 and July 1999. The compression fractures were confirmed with bone scan and spine CT, and bone marrow density was measured. Visual analogue scale(VAS) score was used for pre- and post-operative assessments of the pain. All 159 patients were assessed immediately after surgery, and 140 patients of them were followed-up for about 6 months in average. Results : Partial and complete pain relief was sustained immediately after operation in 73%, through follow-up period in 88% of the patients. Pain relief was not proportional to the amount of PMMA or the rate of increase in the height of the compressed vertebral body. It appears that 3 to 6cc of PMMA was proper enough to sustain pain relief. Better clinical improvement was achieved in the patients treated within 6 months after occurrence of vertebral body fracture. The most frequent surgical complication was epidural leakage of PMMA, and the most serious complication was extravertebral leakage into the paravertebral muscles, which appeared to exert the worst influence on the outcome. However, surgery was not required in these patients. Conclusion : Therapeutic effects of PMMA percutaneous vertebroplasty on osteoporotic vertebral body compression fractures were confirmed in a relatively large scale of prospective clinical study. It appears that good outcome can be achieved in patients treated within 6 months after fracture, treated each level with 3 to 6cc of PMMA in amount. without serious complications.

• 한국도서관정보학회지
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• 제39권3호
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• pp.53-71
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• 2008

본 연구는 예비사서들의 경력결정수준에 미치는 영향력을 분석하기 위해서 수도권 및 충청권 소재 문헌정보학과 재학생을 대상으로 실증연구를 하였다. 외생변수로는 교과과정, 경력관련 학과 활동, 그리고 사서 제도적 요소로 설정하여 조사하였다. 구조방정식모형을 이용하여 분석한 결과, 경력관련 학과활동이 경력결정수준에 영향을 미치는 선행요인으로 분석되었으며, 이 과정에서 성격의 유형이 조절적 역할을 하였다. 이는 예비사서로서의 경력 결정수준을 높이기 위해서는 경력관련 학과 활동 등 예를 들어, 취업동아리, 경력상담 프로그램, 선배와의 교류, 경력프로그램의 실시와 참여 등이 경력관련 정보의 공유를 쉽게하여 경력결정수준을 높인다고 할 수 있다. 이와 아울러 교과과정, 현장 사서가 갖추어야 할 실무능력, 사서자격제도 개선 등의 학교 조직적 사서 제도적 차원의 개선도 이루어져야 할 것이다. 끝으로, 이와 같은 결과를 토대로 연구 한계점 및 추후 연구방향에 대하여 논의하였다.