• Biomolecules & Therapeutics
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• v.11 no.2
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• pp.109-111
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• 2003

The single oral toxicity of Jeju citrus rind pectin (Jeju pectin) was studied in Spraque-Dawley rats of both sexes. In this study, rats were administrated orally with dosages of 100, 250 and 500 mg/kg of Jeju pectin. We daily examined number of deaths, clinical signs, body weights and gross findings for 14 days after Jeju pectin administration. When we administered different doses of 100, 250 and 500 mg/kg. We found no rats died in both sex after administration. Some clinical signs (decrease locomotor activity, salivation, soft stool, prone position, lacrimation, crouching position, convulsion, ataxic gait, incontinence of mine) were also observed during the experimental period.

• Biomolecules & Therapeutics
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• v.9 no.3
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• pp.231-235
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• 2001

The single oral toxicity of JG-381 was studied in Sprague-Dawley rats of both sexes. In this study, rats were administrated orally with dosages of 267, 400, 600, 900 and 1350 mg/kg of JG-381. We daily examined number of deaths, clinical signs, body weights and gross findings for 14 days after JG-381 administration. When we administered different doses of 267, 400, 600, 900 and 1350 mg/kg, we found 1, 4, 4, 5 and 5 male rats died and 3, 5, 4, 5 and 5 female rats died within 1 day after administration, respectively. Some clinical signs (decrease locomotor activity, salivation, soft stool, prone position, lacrimation, crouching position, convulsion, ataxic gait, incontinence of urine) were also observed during the experimental period. Our findings suggest that oral L $D_{50s}$ (95% confidence limit) for male and female rats are 327 mg/kg (270~396 mg/kg) and 250 mg/kg (256~264 mg/kg), respectively.y.

• Journal of Information Processing Systems
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• v.18 no.3
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• pp.332-343
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• 2022

To address the problems of the gravitational search algorithm (GSA) in which the population is prone to converge prematurely and fall into the local solution when solving the single-objective optimization problem, a sine map jumping gravity search algorithm based on asynchronous learning is proposed. First, a learning mechanism is introduced into the GSA. The agents keep learning from the excellent agents of the population while they are evolving, thus maintaining the memory and sharing of evolution information, addressing the algorithm's shortcoming in evolution that particle information depends on the current position information only, improving the diversity of the population, and avoiding premature convergence. Second, the sine function is used to map the change of the particle velocity into the position probability to improve the convergence accuracy. Third, the Levy flight strategy is introduced to prevent particles from falling into the local optimization. Finally, the proposed algorithm and other intelligent algorithms are simulated on 18 benchmark functions. The simulation results show that the proposed algorithm achieved improved the better performance.

• Journal of Biomedical Engineering Research
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• v.36 no.2
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• pp.48-53
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• 2015

Sudden infant death syndrome(SIDS) continues to be general cause of infant death. Also, apnea is supposed to be one of the main risk factor of SIDS. Therefore, Infant's respiratory monitoring and real-time apnea detection is very important to prevent SIDS. In this study, we proposed a non-contact home monitoring system for infant's respiration using Doppler radar in order to prevent SIDS. The respiration data were acquired from a commercialized baby simulator(Simbaby$^{TM}$) using a Doppler radar. To evaluate a performance of the proposed system, the simulator was placed in a supine and prone position and the chest belt was used simultaneously as a reference signal. As a result, correlation coefficients between respiration rates of Doppler radar and the chest belt in each position were 0.95(p < 0.001) and 0.98(p < 0.001), respectively. The averages of difference were $-0.29{\pm}5.21(mean{\pm}1.96{\cdot}$ standard deviation) in supine and $-0.12{\pm}3.05$ in prone from Bland-Altman analysis. The results indicated an excellent performance in detecting apnea with a sensitivity of 100% and a positive predictive value of 100% in each posture respectively. These results demonstrated that a proposed Doppler radar system is suitable for non-contact respiratory monitoring in order to prevent SIDS of infant.

• The Journal of Korean Physical Therapy
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• v.32 no.2
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• pp.101-106
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• 2020

Purpose: This study examined the effects of the directions of neck rotation on the muscle activity of the upper trapezius and lower trapezius while rotating a shoulder externally. Methods: Twenty-five healthy males participated in this study. The subjects were asked to rotate their shoulder externally with 90° shoulder abduction and 90° elbow flexion in three different neck rotations (neutral, ipsilateral, and contralateral) in the prone position. The muscle activities of the upper and lower trapezius were measured using surface electromyography. One way repeated measures ANOVA was used to compare the muscle activity of the upper and lower trapezius depending on the different neck turning directions. Results: In the upper trapezius, turning the neck in the ipsilateral direction while turning a shoulder externally decreased the muscle activity significantly, but the muscle activity was increased significantly by turning the neck in the contralateral direction. On the other hand, in the lower trapezius, turning the neck in the ipsilateral direction increased the muscle activity significantly, but the muscle activity was decreased significantly by turning the neck in the contralateral direction decreased it significantly. Conclusion: When someone has an imbalance of shoulder function, turning the neck in the ipsilateral direction while turning the shoulder externally in the prone position is effective in decreasing the activity of the upper trapezius and increasing the activity of the lower trapezius. Therefore, these results could be used as basic evidence for researching patients with shoulder problems.

• Physical Therapy Korea
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• v.19 no.2
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• pp.12-19
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• 2012

The purpose of this study was to assess the influence of scapular alignment on the electromyographic (EMG) activity of the trapezius in people with a short pectoralis minor muscle. For the study, we recruited 15 volunteers who had positive results for short on a pectoralis minor muscle length test. We measured the EMG activity of the upper, middle and lower trapezius muscles. The participants lifted their dominant arm to ear level with the thumb up toward the ceiling in the prone position on a table with the shoulder at a flexion angle of 180 degrees and a horizontal abduction angle of 120 degrees. Scapula was manually aligned by an experienced physical therapist prior to arm lift for the scapular alignment condition. A paired t-test was used to compare the effects of scapular alignment on the EMG activity of the trapezius muscles. The EMG activity of the lower trapezius muscle was significantly increased during the test with the scapular alignment compared to that without scapular alignment (p<.05), while the upper trapezius and middle trapezius exhibited no significant difference between the two conditions (p>.05). The findings of this study suggest that a scapular alignment may alter the recruitment of the lower trapezius muscle during arm lifting in the prone position in people with a short pectoralis minor muscle.

• Journal of the Korea Convergence Society
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• v.8 no.9
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• pp.175-181
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• 2017

The purpose of this study is to evaluate the breast tool to improve the diagnostic value of the image in the breast examination. Breast tool was made of using FRP. And then it was compared by radioactivity counting rate and image. In the evaluation of the Breast tool, the left and right counts per $1{\mu}Ci$ are 185 counts and 189 counts, respectively. The image obtained in the prone position was close to the circle. To increase diagnostic value of image, it is considered to use Breast-tool in the breast examination.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.3
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• pp.109-115
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• 2019

Purpose : The purpose of this study was to investigate the activity of muscles around the scapulothoracic muscles according to the angle of shoulder joint abduction in the prone position. Methods : The participants included 15 adult males who had not undergone orthopedic surgery and did not have shoulder joint impairments. We measured the muscle activity of the upper trapezius, middle trapezius, lower trapezius, and serratus anterior at $120^{\circ}$, $90^{\circ}$, and $60^{\circ}$ shoulder joint abduction angles. Results : There was a significant difference in the comparison of muscle activity in the upper trapezius, middle trapezius, and serratus anterior muscles according to the shoulder joint abduction angle (p<.05). The results of the post test showed that the upper trapezius was significantly different between $120^{\circ}$ and $60^{\circ}$ (p<.01), and the middle trapezius was significantly different between $90^{\circ}$ and $120^{\circ}$, and between $90^{\circ}$ and $60^{\circ}$ (p<.05). There was a significant difference in the serratus anterior between $120^{\circ}$ and $90^{\circ}$ (p<.01), and $120^{\circ}$ and $60^{\circ}$ (p<.01). Conclusion : The results of this study could be used to determine an effective shoulder joint abduction angle to reduce muscle activity of the upper trapezius and increase muscle activity of the middle trapezius, lower trapezius, and serratus anterior.

• Physical Therapy Korea
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• v.26 no.3
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• pp.23-31
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• 2019

Background: Measurement of passive ankle dorsiflexion range of motion (ADROM) is often part of a physical therapy assessment. Objects: The objective of this study was to identify the effects of subtalar joint neutral position (SJNP) on passive ADROM according to knee position in young adults. Methods: We recruited 14 young adult participants for this study. Two examiners used a universal goniometer to measure passive ADROM with and without SJNP. Dorsiflexion force was applied to the forefoot until maximum resistance was reached in two knee positions (extension and $90^{\circ}$ flexion) in the prone position. Subtalar joint position was also recorded at maximum ADROM. Passive ADROM was measured three times at different knee and subtalar joint positions, in random order. Two-way repeated-measures analysis of variance was used to compare the effects of subtalar joint and knee position on passive ADROM. Results: Passive ADROM was significantly lower with than without SJNP during both knee extension (mean difference: $7.4^{\circ}$) and $90^{\circ}$ flexion (mean difference: $16.9^{\circ}$) (p<.01). Passive ADROM was significantly higher during $90^{\circ}$ knee flexion than during knee extension both with (mean difference: $5.8^{\circ}$) and without SJNP (mean difference: $15.2^{\circ}$) (p<.01). The valgus position of the subtalar joint was significantly lower with than without SJNP during both knee extension (mean difference: $3.3^{\circ}$) and $90^{\circ}$ flexion (mean difference: $4.3^{\circ}$) (p<.01). Conclusion: Our results indicate that the gastrocnemius may limit ankle dorsiflexion more than the soleus does. Greater dorsiflexion at the subtalar and midtarsal joints was observed during passive ADROM measurement without than that with SJNP; therefore, SJNP should be maintained for accurate measurement of ADROM.

• Physical Therapy Korea
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• v.9 no.2
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• pp.33-42
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• 2002

The purpose of this study was to compare the onset times of muscle activities and the order of muscle firing in hamstring gluteus maximus, and lumbar erector spinae muscle during active hip extension between subjects with low back pain (LBP) and healthy subjects. Thirty subjects, 15 with LBP and 15 healthy subjects, participated in this study. Electromyographic activity was recorded during active hip extension in prone and standing position. Relative onset times of these muscle activities were determined. Similar muscle firing order in hamstring, gluteus maximus, and lumbar erector spinae muscle showed in both groups and positions. However, the onset time of gluteus maximus was significantly later in prone and standing active hip extension in subjects with LBP than in healthy subjects. The onset time of lumber erector spinae muscle activity was significantly delayed in subjects with LBP in standing active hip extension, The delayed onset times of gluteus maximus and lumbar erector spinae muscles' activities were probably related to LBP. Further studies are needed to identify whether the delayed onset times of gluteus maximus and lumbar erector spinae muscle activities are the contributing factors to LBP.