• Biomedical Science Letters
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• v.10 no.1
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• pp.23-29
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• 2004

Nebulin is a (Mr 600∼900 kDa) large actin-binding protein specific to skeletal muscle and thought to act as a molecular template that regulates the length of thin filaments. Cardiac muscles of higher vertebrates have been shown earlier to lack nebulin. Recently, full-length nebulin mRNA transcripts have been detected in heart muscle, but at lower levels than in skeletal muscle. Nebulin expression also was detected in the kidney, eye, and otic canal, suggesting that nebulin isoforms may also be expressed in these organs. We have searched for nebulin isoforms in brain of human using PCR and Northern blot. Here, we provide evidence that nebulin mRNA transcripts are expressed in brain. Seven nebulin isoforms (B, C, D, E, F, G and H form) are obtained in human skeletal muscle and four isoforms (B, C, G and H form) in human brain cDNA library. We cloned the 1.3 kb of nebulin fragment from human adult brain library by PCR. The identity of the PCR product was confirmed by sequence analysis. The partial brain nebulin sequence was 99% identical to the skeletal muscle cDNA as determined by Blast alignment. It contains two simple-repeats HR1, HR2 and linker-repeats exon l35∼143 except exon 140. It was different from skeletal muscle B form, which contain HR1 and HR8. These data suggest that nebulin isoform diversity occurs even more extensively than previously known, likely contributing to the distinct thin filament architecture of different striated muscles.

• The Journal of the Korea institute of electronic communication sciences
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• v.9 no.4
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• pp.447-454
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• 2014

Recently most of functional synthesis methods for quantum circuit realization have a tendency to adopt the declarative functional expression more suitable for computer algorithms, so it's difficult to analysis synthesized quantum functions. This paper presents a new functional representation of quantum circuits compatible with simple architecture and intuitive thinking. The proposal of this paper is a new functional synthesis development by using the control functions as the power of corresponding to affine-controlled quantum gates based on the mathematical substitution of serial-product matrix operation over the target line for the arithmetic and modulo-2 ones between power functions of unitary operators. The functional synthesis algorithm proposed in this paper is useful for the functional expressions and synthesis using both of reversible and irreversible affine-controlled NCV-quantum gates.

• Korean Institute of Interior Design Journal
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• v.24 no.3
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• pp.68-78
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• 2015

Nendo, which was established in Tokyo in 2002, is a design company established by Oki Sato, which is gaining reputation as a new design group representing Japan through numerous design tasks encompassing diverse design sectors, such as architecture, interior, furniture, graphic, and products. This study was conducted to investigate the formative features of Nendo furniture by reviewing 133 pieces of Nendo furniture designed for the last ten years and identify the general characteristics of Nendo furniture by reviewing the time of launch, product launch type, and furniture type. As a result, the design features of Nendo furniture are as follows: First, the shapes of basic materials including boards, lumber, and bars are maintained intact and Nendo furniture has simple and moderate design without complicated or decorative elements. Second, Nendo furniture has simply embodied a design characterized by simple transformation, minimization of furniture elements, and rearrangement. Third, Nendo presents new and simple furniture differentiated from other pieces of furniture using optical illusions. Such expressions of optical illusions which are hardly found in preexisting furniture are a major feature of Nendo furniture. Fourth, a majority of chairs of Nendo cause optical illusions with the minimized size. In addition, their top boards made of transparent glass and mirror cause optical illusions with the properties of materials. In short, design of Nendo furniture is characterized by formative expressions, expressions of optical illusions, and differentiated use of materials. Fifth, Nendo keeps launching new furniture items in various exhibitions. As a result, Nendo makes furniture with its own unique characteristics based on its diverse studies and experiments which are applied to furniture design in a realistic way. In summary, design of Nendo furniture is characterized by simply embodied design based on small differences in daily life, minimalism with simple and moderate shapes, and its own witty uniqueness based on formative expressions, expressions of optical illusions, and use of materials differentiated from other furniture brands.

• Journal of KIISE:Software and Applications
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• v.35 no.8
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• pp.479-492
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• 2008

Nowadays, lots of requirements are changed quickly and variously. So, we need the ability to support the change of business process which is the asset of a company. To support this ability, the core asset that supports analyzing and describing about changes of business process should be exist from generating phase of a business process model. And a business process model that is satisfied the changed requirements should be automatically generated using core assets. In this paper, we present a business process family model (BPFM) which represents the commonalities and the variabilities of a set of business processes, we propose the automated tool using variabilities of BPFM and decision-making information for generation of business process model that is satisfied the changed requirements.

• Journal of Internet Computing and Services
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• v.5 no.4
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• pp.95-113
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• 2004

RUP(Rational Unified Process) is a development process which is based on object-oriented, use case centric, architecture centric, and iterative approach. Public projects performed previously adopt waterfall lifecycle model for development of large scale software. However, recently various projects adopt an iterative approach to minimize risks of a project and to enhance quality of software. But few research result on practices of RUP as the subprocess of system development process is available. This paper presents a system development process which uses RUP as the subprocess for a subset of the system. Thus we introduce a tailored RUP for K-CIS(Korean Core Instrumentation System). Moreover, we assess the application result of K-CIS with typical waterfall lifecycle model and RUP. We believe that the results of our work are useful for tailoring a system development process with RUP, reducing risks of development, and enhancing the quality of a final product.

• KIISE Transactions on Computing Practices
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• v.20 no.12
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• pp.664-669
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• 2014

As the prevalence of cloud computing increases, various cloud service types have emerged, such as IaaS, PaaS, and SaaS. The growth and diversification of these cloud services has also resulted in the development of technology for cloud service brokers (CSBs), which serve as intermediate cloud services that can assist cloud tenants (users) in deploying services that fit their requirements. In order to broker cloud services, CSBs require the specification of structural models in order to facilitate the analysis and search for cloud services. In this study, we propose a variability-based service analysis model (SAM) that can be used to describe various cloud services. This model is based on the concept of variability in the software product line and represents the commonality and variability of cloud services by binding variants to each variation point that exists in the specification, quality, and pricing of the services. We also propose a virtual cloud bank architecture as a CSB that serves as an intermediate to provides tenants with appropriate cloud services based on the SAM.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.373-380
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• 2020

A valve product can be over-designed or too heavy. Finite element analysis was performed using ANSYS for two and three-dimensional ball valve models, and the ball weight was reduced by optimization within the allowable design criteria. The ball is structurally safe according to the computed stress values, which are within the material's admissible stress. The weight was reduced by about 22%, and the structural safety factor was 1.25. The structural safety of the seat insert and ring, which are used to prevent leakage, was confirmed through finite element analysis. It is shown that the two-dimensional analysis can result in similar values to the three-dimensional analysis for the axisymmetric structure. The redesign of the valve is not included in the results since such changes require a whole new design process, including all valve components.

• Journal of the Korean Society for Marine Environment & Energy
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• v.11 no.1
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• pp.46-49
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• 2008

Recycling glass fiber, 'F-fiber,' was obtained by the separation of the roving layer from waste FRP and the concrete products or structures were considered for its application. Experiment was carried out for the bending strength of aggregate (2.45 of cement) by weight and F-fiber (density of 1.45, volume ratio to all of the aggregate and the cement). Whereas the specimen containing 1% F-fiber showed the bending strength 23% higher than that without F-fiber after curing far 28 days, the one with 0.5% F-fiber did not give any change. It could be found, therefore, that the minimum mixing amount should be larger than 0.5% fur the strength reinforcement. One of the reinforcing concrete product, bench flume, containing 1% F-fiber showed 21% increment of bending strength In contrast to that without F-fiber.

• Journal of Intelligence and Information Systems
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• v.9 no.2
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• pp.121-133
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• 2003

Due to the rapid growth of Internet, means of communication with customers in a traditional customer support environment such as telephone calls are being replaced by mainly e-mail in a Web-based customer support system. Although such a Web-based support is efficient and promises potential benefits for firms, including reduced transaction costs, reduced time, and high quality of support, there are some difficulties associated with responding to many types of customer's inbound e-mails appropriately. As many types of e-mail are received, considerable attention is being paid to methods for increasing the efficiency of managing and responding e-mails. This research proposes an intelligent system for managing customer's inbound e-mails in organizations by applying case based reasoning technique for responding to various customers' inbound e-mails more effectively. In this approach, a case is represented as a frame-typed data structure corresponding to an inbound e-mail, keywords, and its reply e-mail. In the retrieval procedure, keywords and affinity set is developed to index a case, and then the case is represented as a vector, a case vector. Also, cosines value is calculated to measure the similarity between a new inbound e-mail and the cases in the case base. In the adaptation procedure, we provide several adaptation strategies to adapt and modify the retrieved case. The strategies guide to make an outbound e-mail using product databases, databases for customer support, etc. Additionally, the Web-based system architecture is proposed to implement our methodology. The proposed methodology and system will be helpful for developing more efficient Web-based customer support.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.2B
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• pp.296-301
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• 2010

Radio frequency identification(RFID) system can identify an object using wireless transmission. RFID applications are numerous and far reaching. The most interesting and widely used applications are supply chain management for companies. Currently, RFID tags must be detached or killed for security and privacy reasons when tagged objects are purchased. In this paper, we present a new architecture that transfers information about products from the electronic product code information services (EPCIS) server of a company to an individual's personal purchases management (PPM) server when products with RFID codes are sold. It solves the security and privacy issues without detaching the tag. Moreover, the PPM server described in this paper allows customers to handle the expiration dates, updates, location management, and group management of products.