• 제목/요약/키워드: Product architecture

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Differential Expression of Kidney Proteins in Streptozotocin-induced Diabetic Rats in Response to Hypoglycemic Fungal Polysaccharides

  • Hwang, Hye-Jin;Baek, Yu-Mi;Kim, Sang-Woo;Kumar, G. Suresh;Cho, Eun-Jae;Oh, Jung-Young;Yun, Jong-Won
    • Journal of Microbiology and Biotechnology
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    • v.17 no.12
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    • pp.2005-2017
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    • 2007
  • Diabetic nephropathy remains a major cause of morbidity and mortality in the diabetic population and is the leading cause of end-stage renal failure. Despite current therapeutics including intensified glycemic control and blood pressure lowering agents, renal disease continues to progress relentlessly in diabetic patients, albeit at a lower rate. Since synthetic drugs for diabetes are known to have side effects, fungal mushrooms as a natural product come into preventing the development of diabetes. Our previous report showed the hypoglycemic effect of extracellular fungal polysaccharides (EPS) in streptozotocin (STZ)-induced diabetic rats. In this study, we analyzed the differential expression patterns of rat kidney proteins from normal, STZ-induced diabetic, and EPS-treated diabetic rats, to discover diabetes-associated proteins in rat kidney. The results of proteomic analysis revealed that up to 500 protein spots were visualized, of which 291 spots were differentially expressed in the three experimental groups. Eventually, 51 spots were statistically significant and were identified by peptide mass fingerprinting. Among the differentially expressed renal proteins, 10 were increased and 16 were decreased significantly in diabetic rat kidney. The levels of different proteins, altered after diabetes induction, were returned to approximately those of the healthy rats by EPS treatment. A histopathological examination showed that EPS administration restored the impaired kidney to almost normal architecture. The study of protein expression in the normal and diabetic kidney tissues enabled us to find several diabetic nephropathy-specific proteins, such as phospholipids scramblase 3 and tropomyosin 3, which have not been mentioned yet in connection with diabetes.

Design and Development of a u-Market System for Traditional Market Revitalization (재래시장 활성화를 위한 u-Market 시스템 아키텍처 설계 및 시스템 개발)

  • Kim, Jae-Kyeong;Choi, Il-Young;Chae, Kyung-Hee;Kim, Hyea-Kyeong;Ji, Yong-Gu;Jung, Hye-Jung
    • Journal of Intelligence and Information Systems
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    • v.14 no.2
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    • pp.103-119
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    • 2008
  • Traditional market which is characterized by the folksy retailing market has lost its competitiveness rapidly due to the emergence of the Internet and the change of customer's purchasing behavior. The recession of the traditional market contracts the regional economy. We suggest a u-Market, a traditional market with ubiquitous computing capability, to revitalize traditional market. The suggested u-Market system applies ubiquitous computing technologies characterized by communications between customers and objects without limitations of time and location. The proposed u-Market system offers location information and specific contents of traditional market to customers. Furthermore, u-Market system recommends the store and product list that customers are likely to visit and purchase based on their contexts, so they can save their time and effort to search the products or contents.

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An Analysis on the Re-visitation Choice of Rural Leisure - Focused on Buraemi, Daraengi, Byucgari region - (농촌여가 시장의 재방문 선택요인 분석 -부래미, 다랭이, 볏가리지역을 대상으로-)

  • Yun, Hee-Jeong;Im, Seung-Bin
    • Journal of Korean Society of Rural Planning
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    • v.14 no.2
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    • pp.33-42
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    • 2008
  • Recently, rural leisure by urban dwellers has been recognized as a catalyst for regional development or restoration. The federal government implemented several regional planning policies attempting to address this phenomenon in the late nineties. However, most of these policies focused on supply-centered planning, which caused a diverse set of problems relating to the sustainability and economic validity of the planning. Instead, this study focuses on the re-visitation one of the demand variables, with the intention of analyzing the character of rural leisure demand and its re-visitation choice attributes. For these reasons, this study investigates the character of current rural leisure demand, and develops functional equations about urban people who visit rural areas, using logit model. The results of this study can be summarized as follow: Urban people are visiting rural areas from nearby cities or metropolitan areas that are within 3 hours driving distance, and over 80% of rural visitors are one-day visitors. Therefore, most of their visitation activities should be understood as rural leisure, including rural tourism. In addition, the likelihood of the rural tourist to make a return visit is influenced by their transportation means, product purchasing, staying period and travel time. The results of such rural leisure demand can provide information for regional planning strategies, such as selection of target market, type of market segments, improvement of recognition level, activity program price, facility and space planning, produce sale and connection with tour site.

The Recovery Techniques on the Web Services-based e-Engineering Framework for Reliability Improvement (웹 서비스 기반 e-엔지니어링 프레임워크의 신뢰성 향상을 위한 회복 기법)

  • Kim, Dong-Uk;Kuk, Seung-Hak;Kim, Hyeon-Soo;Lee, Jai-Kyung
    • Journal of KIISE:Computing Practices and Letters
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    • v.14 no.1
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    • pp.76-80
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    • 2008
  • In order to reduce a product life cycle and to improve productivity, it is required to automate the design/analysis processes. In general, since the design/analysis processes need a lot of time and resources, the various engineering resources should be integrated and utilized effectively in the distributed environments. KIMM (Korea Institute of Machinery and Materials) constructed the SOA-based e-Engineering framework to automate the execution of the design/analysis processes and to integrate the engineering resources in the distributed environments. This paper presents the concepts and the structures of the e-Engineering framework. Also it classifies the exceptional cases that will be able to occur in the e-Engineering framework and suggests the recovery techniques from the exceptional cases with viewpoints of the engineering process and the task, respectively.

New Perspective of Forest Recreation Program in Gangwon-do (강원도(江原道) 자연휴양림(自然休養林) 프로그램의 방향(方向) 모색(摸索))

  • Lee, Yong-Gyu;Choi, Jung-Kee
    • Journal of Forest and Environmental Science
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    • v.20 no.1
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    • pp.28-39
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    • 2004
  • This study was carried out to find new perspective of forest recreation program in Gangwon-do. Gangwon-do has now 19 forest recreation sites (national forest 11, public forest 4, private forest 4) where forest interpretation, mountain bike, mountain marathon, mountain ski, forest music concert, various forest class are held. In order to develop the new programs for forest recreation program in Gangwon-do, this study considered culture program, welfare program and education program. For culture program, the experience program in traditional house, the experience in the back region and the experience in special product of mountain village were suggested. For welfare programs, the welfare programs for the old and the handicapped were shown. For education program, forest global village program and personality program were devised. According to introduction of 5 day-work per week, the population for recreation are expected to strongly increase, so Gangwon-do representing the image of tour province should improve continuous concern and various developing programs for forest recreation.

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A Study on the Enterprise Application Framework for Developing Efficient RFID Applications (효율적인 RFID 애플리케이션 개발을 위한 엔터프라이즈 애플리케이션 프레임워크에 관한 연구)

  • An, Kyu-Hee;Yang, Seok-Hwan;Chung, Mok-Dong
    • Journal of Korea Multimedia Society
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    • v.11 no.2
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    • pp.269-280
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    • 2008
  • The information flow through RFID techniques such as, standardized EPC and EPCglobal network suggests new change in the method of cooperating and sharing information in the supply chain. Common function should be prepared for communication, security techniques, and business processes based on the EPCglobal standard to introduce efficient RFID techniques. And the standard architecture which can deal with the RFID environment flexibly is quite necessary. Therefore, this paper suggests Enterprise Application Framework (EAF) for developing efficient and secure RFID applications. EAF offers essential services to develop RFID enterprise systems : a communication environment which uses various standard communication protocols, a security function based on PKI, and abstract business services for flexible introduction of RFID businesses. It simplifies the RFID business integration, minimizes the development complexity, and thus EAF is expected to reduce the cost of RFID application development. EAF guarantees constructing secure RFID applications due to PKI-based security mechanism.

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H-refined Shape Design Sensitivity Analysis of Elastic Structures using Multi-Resolution Approach (다중 조밀도를 이용한 탄성 구조의 h-세분화 아이소-지오메트릭 설계민감도 해석)

  • Lee, Taeho;Yoon, Minho;Cho, Seonho;Koo, Bonyong
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.31 no.3
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    • pp.155-163
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    • 2018
  • One of the major disadvantages of isogeometric analysis(IGA) is that local refinement is nearly impossible in a conventional manner because of the tensor product nature in NURBS. In this research, we investigate a local refinement scheme for isogeometric analysis, named multi-resolution approach where different resolutions are employed at each subdomain, using h-refinement relation to endow displacement compatibility on an interface of subdomains. Then, we develop shape sensitivity analysis possessing same compatibility condition as in the analysis. Numerical examples are shown to demonstrate the computational efficiency of the method in analysis especially stress concentration problem and accurate sensitivity results which is also compatible on the interface.

A study on the havesting process and operating behaviour of working ships for farming laver (김 양식장 채취선의 운항거동과 수확조업에 관한 연구)

  • KIM, Ok-sam;MIN, Eun-bi;HWANG, Doo-jin
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.56 no.3
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    • pp.223-229
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    • 2020
  • We analyzed the cutting mechanism of laver harvesting machine in the sea area near Gooam Port in Goheung, Jeollanam-do, and investigated the change and efficiency of laver collecting operation in the working ship. The laver working ship slides uniformly from the bow to the upper part of the laver collecting machine on the deck and cuts the wet laver attached to the bottom of the net at the blade of the havesting machine. The laver farming net, which was loaded with laver turrets on the deck by gravity and collected primitives, consisted of a ship structure that led to the stern side and into the sea. The working ship operation is in harvesting process while driving in a S-shape that is separated by one space to efficiently collect the laver net. During laver working ship operation, the speed was 0.51 m/s in the access stage, 0.56 m/s in the havesting stage, and 0.52 m/s in the exit stage. Considering the cutting edge life and production efficiency of the laver harvesting machine, it is appropriate to harvest 1.15 to 1.26 kg/rpm by operating at a rotational speed of about 700 to 800 rpm rather than forcibly harvesting the product at high speed. On the deck of the working ship, 959.7 kg of starboard and 1048.7 kg of center were 964.7 kg of port side. Based on the starboard, 9.3% of the central part and 0.5% of the port side appeared. The reason for this was due to the difference in harvest time according to the turning direction of the working ship.

Evaluation of Dispersion Characteristics for Liquefied Red Mud by Viscosity and Sediment Index (점도 및 침전지수에 의한 액상화 레드머드의 분산 특성평가)

  • Kang, Suk-Pyo;Kang, Hye-Ju
    • Journal of the Korea Institute of Building Construction
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    • v.17 no.6
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    • pp.517-525
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    • 2017
  • Red mud is an industrial by-product produced during the manufacturing aluminum hydroxide ($Al(OH)_3$) and aluminum oxide($Al_2O_3$) from Bauxite ores. In Korea, approximately 2 tons of red mud in a sludge form with 50% moisture content is produced when 1ton of $Al_2O_3$ is produced through the Bayer process. In the paper, dispersion characteristics of liquefied red mud that does not require heating and grinding process for recycling were investigated through viscosity and sediment index. The results showed that the sediment index of liquefied red mud increased but viscosity of that decreased with a higher W/R ratio. Also we proposed the range of initial viscosity from 2000cP to 8000cP and target sedimentation index below 20% at elapsed time 180days for stable dispersion of liquefied red mud.

Consumer Awareness Survey for Environmentally Friendly Children's Furniture Development (친환경 아동용 가구 개발을 위한 소비자 인식 조사)

  • Kim, Ja Kyung
    • Journal of the Korea Furniture Society
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    • v.28 no.4
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    • pp.340-354
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    • 2017
  • Currently, the global furniture market can not overlook environmental problems due to changes in environmental regulations. In order to grow into a global corporation, environmentally friendly design became essential. In addition, domestic and foreign consumers are increasingly interested in and spending on children's furniture, and demand for environment - friendly furniture for children's health and emotional development is increasing. In the era of universal consumer tastes due to massive mass production, it has been changed into a multi-product small-volume production period that reflects the preferences of various consumers, so that various types of furniture that meet individual preferences are required. Therefore, in this study, we investigated various personal opinions, perception, preference, propensity to use furniture, purchasing points, etc. for environmentally friendly children's furniture, and provided basic data for environmentally friendly children's furniture development that reflects consumer preference and requirements. Accordingly, 243 parents who have more than one child living in Seoul, Gyeonggi, and Incheon were surveyed about the use of children's furniture and the perception and preference of environmentally friendly children's furniture. According to the survey results, 64.57% of the respondents knew about eco - friendly children's furniture and the most popular way to get to know eco-friendly furniture was Internet advertising (49.48%). The rate of recognizing eco-friendly furniture as healthy furniture with no emission of hazardous substances was high as 56.16%. The purchase intention of eco-friendly children's furniture was very high at 86.01% and the most important factor in purchasing was the harmlessness to the human body (56.88%). 59.50% said that it is not possible to distinguish environmentally friendly furniture, which means that there is not much information to consumers yet. In addition, the preferred price range is 500~1000 thousand won, and the preference for the rest furniture is high. In the preferred form type, unit type modular furniture is 36.13%, in the material, wood is 72.35%, in the color, the color of wood with wood grain is high as 45.56%.