• Journal of Pharmacopuncture
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• v.13 no.1
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• pp.63-77
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• 2010

Objectives: The aim of this experiment is to provide an objective differentiation of cultivated ginseng, cultivated wild ginseng, and wild ginseng through component analysis, and to know the change of ginsenoside components in the process for making red ginseng. Methods: Comparative analysis of ginsenoside $Rb_1,\;Rb_2$, Rc, Rd, Re, Rf, $Rg_1,\;Rg_3,\;Rh_1$ and $Rh_2$ from the cultivated ginseng 4 and 6 years, cultivated wild ginseng, and wild ginseng were conducted using High Performance Liquid Chromatography(hereafter HPLC). And the same analyses were conducted in the process of red ginseng. Results: 1. For content comparison of ginsenoside $Rb_1$, Rc, Rd, Rf, $Rg_1$ and $Rh_1$, wild ginseng showed high content, followed cultivated ginseng 4 and 6 years, cultivated wild ginseng showed low content than any other samples. 2. For content comparison of ginsenoside $Rb_2$ and Re, cultivated ginseng 4 years showed high content, followed wild ginseng and cultivated ginseng 6 years, cultivated wild ginseng showed low content than any other samples. 3. For content comparison of ginsenoside $Rg_3$, wild ginseng and cultivated wild ginseng were only showed low content. 4. For content comparison of ginsenoside $Rh_2$, cultivated wild ginseng was only showed low content. 5. In the process of red ginseng, ginsenoside $Rb_1,\;Rb_2$, Rc, Rd, $Rg_3$ and $Rh_1$ were increased, and ginsenoside Re and $Rg_1$ were decreased in cultivated wild ginseng. 6. In the process of red ginseng, ginsenoside $Rg_3$ and $Rh_1$ were increased, and ginsenoside $Rb_2$, Rc, and Re were decreased in cultivated ginseng 4 years. 7. In the process of red ginseng, ginsenoside $Rb_1,\;Rb_2$, Rf and $Rh_1$ were increased, and ginsenoside Rc and Rd were decreased in cultivated ginseng 6 years. Conclusions: Distribution of ginsenoside contents to the cultivated ginseng, cultivated wild ginseng, and wild ginseng was similar and was not showed special characteristics between samples. And the change of ginsenoside to the process of red ginseng, cultivated ginseng and cultivated wild ginseng were showed different aspect.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.19 no.37
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• pp.53-61
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• 1996

Recently the business transformaton of a company is achieved through the business process re-design and total quality management concept. This paper focused on the decision of the critical measurement point(CMP) for maximizing the effectiveness of the business process reengineering. In general, the types of business processes can be classified into two kinds, serial processes with IPO(input/process/output) type and non-serial processes with workflow type. The traditional method of selecting the CMP relies on the experiences and intuitions of the process owners. We suggest a mathematical method for more objective selection of CMP by using Dynamic Programming.

• Journal of the Korean Society for Precision Engineering
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• v.23 no.7 s.184
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• pp.93-100
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• 2006

Post industrial technologies have improved human standard of living, however, a host of negative environmental consequences from the unlimited industrial appetite have posed serious global challenges. Remanufacturing is an industrial manufacturing process that is to restore old products to perform like a new and to save energy, natural resources, landfill space and to reduce air pollution by less re-smelting. By extending product lift cycle, remanufacturing gives us enormous opportunities for sustainable development of our society. This paper introduces needs and current state of the art in the field of remanufacturing, also analyzes old products in terms of product variety and wear conditions with an example of automobile alternators. Then, a general and a product-specified remanufacturing process will be determined with them. Finally, this paper shows systemized guidelines for remanufacturing process of the specified parts. The results could be also used as a basic information for further remanufacturing applications.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1999.10a
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• pp.378-386
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• 1999

The integrated system for the structural analysis of space frame is made up 4 modules ; pre-process module, structural analysis module, optimum member design module and post-process module. Re-process module of these 4 modules involves data input module and structure modeling module. This study is to develope an efficient modeling program as a basic for development of pre-process module. This modeling program generates geometric information of space frame and performs the input fie form for structure analysis only by input general data. User can mode1 space frame efficiently within shut time by using this program.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.23 no.56
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• pp.19-34
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• 2000

Impact of business process re-engineering requires the fundamental rethinking of how information systems are analyzed and designed. It is no longer sufficient to establish a monolithic system for fixed business environments. Information systems must be adaptive in nature. This demand is also applied in production domain. Enabling concept for the adaptive information system is reusability. This paper presents a new object-oriented analysis process for creating such reusable software components in production domain, especially for production planning and scheduling. Our process called MeCOMA is based on three meta-models: physical object meta-model, data object meta-model, and activity object meta-model. After the three meta-models are extended independently for a given production system, they are collaboratively integrated on the basis of integration pattern. The main advantages of MeCOMA are (1) to reduce software development time and (2) to consistently build reusable production software components.

• The Transactions of the Korea Information Processing Society
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• v.3 no.1
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• pp.200-210
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• 1996

Re-engineering has the potential to improve software productivity and quality y across the entire life cycle. It involves improving the software maintenance process and improving existing systems by applying new technologies and tools to software maintenance. Re-engineering can help us understanding existing systems and discover software components(e.g., design structure, data structure that are common across systems. These common components then can be reused in the development (or redevelopment )of systems, thereby significantly shortening the time and lessening the risk of developing systems. The Object-Oriented paradigm has been known to improve software maintainability. There still exist many problems in recognizing object, attributes and operations that are conceptually integrated and constructing of object class. In this paper, we propose a method that defines a fundamental theories of re-engineering and a concept recognition for object- oriented paradigm. We also describe the re-engineering tool that translates the existing procedure-oriented program into object-oriented system. This tool has a strength to solve the conceptual integrity problem in object-oriented recognition.

• The Transactions of the Korea Information Processing Society
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• v.1 no.3
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• pp.299-310
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• 1994

Re-engineering tools can substantially increase software maintenance productivity and the quality of maintenance work. Re-engineering usually involves changing the form(e.g.changining objects names and definitions, restructuring process logic) of a program. In this paper, we describe the design and implementation of InMaC＋＋ that is a software tool oriented towards maintenance of C＋＋ object oriented programs. With InMaC＋＋, programms can be displayed and edited in two forms : as the code and as the diagram InMaC＋＋ also contains transformations in both directions, i,e. from code to diagram and from diagram to skeletons of code. Hence, it is suitable for re-engineering and maintenance of existing code. Specially designed browsers implement the graphical interface. InMaC＋＋ contains a database that is based on a simple but effective data model of InMaC＋＋ programs. The model contains only four object classes and three relations, which makes the tool small, and easy to implement and use. A simple query language allows browsing through the database.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.26 no.2
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• pp.98-103
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• 2013

The alumina substrates that Ni electrode was printed on and the multi-layered PTCR thermistors of which composition is $(Ba_{0.998}Ce_{0.002})TiO_3+0.001MnCO_3+0.05BN$ were fabricated by a thick film process, and the effect of re-oxidation temperature on their resistivities and resistance jumps were investigated, respectively. Ni electroded alumina substrate and the multi-layered PTC thermistor were sintered at $1150^{\circ}C$ for 2 h under $PO_2=10^{-6}$ Pa and then re-oxidized at $600{\sim}850^{\circ}C$ for 20 min. With increasing the re-oxidation temperature, the room temperature resistivity increased and the resistance jump ($LogR_{290}/R_{25}$) decreased, which seems to be related to the oxidation of Ni electrode. The small sized chip PTC thermistor such as 2012 and 3216 exhibits a nonlinear and rectifying behavior in I-V curve but the large sized chip PTC thermistor such as 4532 and 6532 shows a linear and ohmic behavior. Also, the small sized chip PTC thermistor such as 2012 and 3216 is more dependent on the re-oxidation temperature and easy to be oxidized in comparison with the large sized chip PTC thermistor such as 4532 and 6532. So, the re-oxidation conditions of chip PTC thermistor may be determined by considering the chip size.

• Journal of KIISE:Computing Practices and Letters
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• v.16 no.3
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• pp.301-315
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• 2010

Recently, competition between companies has intensified and so has the necessity of creating a new business value inventions has increased. A numbers of Business organizations are beginning to realize the importance of business process management. Processes however can often not go the way they were initially designed or non-efficient performance process model could be designed. This can be due to a lack of cooperation and understanding between business analysts and system developers. To solve this problem, business process mining which can be used as the basis of the business process re-engineering has been recognized to an important concept. Current process mining research has only focused their attention on extracting workflow-based process model from competed process logs. Thus there have a limitations in expressing various forms of business processes. The disadvantage in this method is process discovering time and log scanning time in itself take a considerable amount of time. This is due to the re-scanning of the process logs with each new update. In this paper, we will presents a modified FP-Tree algorithm for FP-Tree based business processes, which are used for association analysis in data mining. Our modified algorithm supports the discovery of the appropriate level of process model according to the user's need without re-scanning the entire process logs during updated.

• Nuclear Engineering and Technology
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• v.55 no.2
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• pp.669-673
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• 2023

Introduction: The crucial step in preclinical process of radiopharmaceutical production is internal dosimetry evaluation by different ways to realize radiobiological dose-response relationships and to extract the results for clinical use. Till now several bone-seeking radiopharmaceuticals have been developed for bone metastasis. Interesting features of bisphosphonates attracted attentions to them in the field of radiopharmaceutical therapy and studies on new generation of them have been doing too. Materials and methods: In this study, we used ZNA as representative of the third generation. The radiopharmaceutical ¹⁸⁸Re-ZNA was produced and its radiochemical purity was investigated. Then, the biological distribution of the produced radiopharmaceutical at 1, 2, 4 and 24 h after injection on different organs of mice were investigated. Finally, the absorbed dose of organs in the human body was assessed using the RADAR method. Results: The results show 96% radiochemical purity of the ¹⁸⁸Re-ZNA radiopharmaceutical. The amount of %ID/g in bone is 1.131% after 1 h and in 24 h it has a significant amount compared to other organs, that is 0.516%. Also dosimetric results show that the highest absorption dose is related to bone and the amount of this dose is 0.050 mGy/MBq. Conclusion: Considering the possibility of producing the ¹⁸⁸Re-ZNA radiopharmaceutical, as well as the proper distribution of this radiopharmaceutical in target and non-target organs and increasing the absorbed dose in bone, it can be concluded that this radiopharmaceutical can be useful in the "radiopharmaceutical therapy" in metastases.