• Asian-Australasian Journal of Animal Sciences
• /
• v.22 no.8
• /
• pp.1160-1166
• /
• 2009

This study was conducted according to the single-factor design principle to investigate in vitro the effects of different glucagon-like peptide-2 (GLP-2) concentrations (0, $1{\times}10^{-11}$, $1{\times}10^{-10}$, $1{\times}10^{-9}$, $1{\times}10^{-8}$ and $1{\times}10^{-7}$ mol/L) on the morphology, proliferation and enzyme activity of intestinal enterocyte cells of 28-d-old weaned piglets. These cells were primary cultured in 4 pieces of 24-well cell culture plate. After having been grown for 48 h in culture media with hGLP-2, the ileal enterocyte cells of 28-d-old weaned piglets exhibited the typical characteristics of simple columnar epithelium. Compared with the control groups, the quantities of treated cells significantly increased (p<0.05) and their corresponding absorption values in 540 nm (MTT OD) also significantly increased (p<0.01). Likewise, lactic acid concentration, total protein content and protein retention significantly increased (p<0.05). $Na^{+}$, $K^{+}$-ATP enzyme activity was more active (p<0.05), although the activity of alkaline phosphatase, lactic acid dehydrogenase and creatine phosphokinase in culture media significantly decreased (p<0.01). To summarize, the results indicated that GLP-2 in vitro is capable of promoting the proliferation of intestinal enterocyte cells of 28-d weaned piglets, restraining their apoptosis and maintaining the integrity of their morphology.

• Applied Biological Chemistry
• /
• v.48 no.1
• /
• pp.16-22
• /
• 2005

Many chitosanases, glycosyl hydrolases that catalyze the degradation of chitosan, have been found in microorganism. In this paper, classification of the enzyme has been described, which is based on the amino acid sequence (families) and splitting patterns (subclasses). Glycohydrolytic mechanisms such as inversion and retention of the substrate anomer are also discussed in context of the families. Interrelationship among the primary structure, clan, anomeric conversion and the splitting patterns has been suggested. In addition, advanced definition of chitosanase was introduced through the investigation of enzymatic products from partially N-acetylated chitosan as a substrate.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.28 no.1
• /
• pp.80-86
• /
• 2006

Cleidocranial dysplasia is rare inherited skeletal dysplasia. It was first reported by Martin in 1765. Subsequently, Marie and Sainton independently documented the criteria of the disease. Cleidocranial dysplasia is a bone disorder caused by a defect in the CBFA1 gene of chromosome 6p21. This gene guides osteoblastic differentiation and appropriate bone formation. Patient with cleidocranial dysplasia has maxillary deficiency, high and narrow palate, prolonged retention of primary teeth, unerupted permanent teeth and supernumerary teeth. Therapeutic options in these patients include of autotransplantation of selected impacted teeth, forced eruption of permanent teeth, full denture, overdenture and implant-supported prosthesis. We report a patient with cleidocranial dysplasia. This patient was treated with implant supported bar overdenture. Despite of gene defect that affects osteoblastic activity, bone remodeling and osseointegration occurred in our patient. So, we report this case with review of literature.

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.8 no.1
• /
• pp.66-79
• /
• 2008

Several oxides have recently been reported to have resistance-switching characteristics for nonvolatile memory (NVM) applications. Both binary and ternary oxides demonstrated great potential as resistive-switching memory elements. However, the switching mechanisms have not yet been clearly understood, and the uniformity and reproducibility of devices have not been sufficient for gigabit-NVM applications. The primary requirements for oxides in memory applications are scalability, fast switching speed, good memory retention, a reasonable resistive window, and constant working voltage. In this paper, we discuss several materials that are resistive-switching elements and also focus on their switching mechanisms. We evaluated non-stoichiometric polycrystalline oxides ($Nb_2O_5$, and $ZrO_x$) and subsequently the resistive switching of $Cu_xO$ and heavily Cu-doped $MoO_x$ film for their compatibility with modem transistor-process cycles. Single-crystalline Nb-doped $SrTiO_3$ (NbSTO) was also investigated, and we found a Pt/single-crystal NbSTO Schottky junction had excellent memory characteristics. Epitaxial NbSTO film was grown on an Si substrate using conducting TiN as a buffer layer to introduce single-crystal NbSTO into the CMOS process and preserve its excellent electrical characteristics.

• Journal of the Korean Chemical Society
• /
• v.32 no.5
• /
• pp.483-494
• /
• 1988

The adsorption behavior of aromatic acids on Amberlite XAD-4 resin was investigated by measuring the distribution coefficient by batch method. The adsorption of solutes on XAD-4 was affected by the several factors such as, analyte concentration, the pH of solution and concentration of pairing ion. The enhanced adsorption of solutes on XAD-4 in the presence of tetraalkylammonium salt as an ion pairing reagent, referred to as ion interaction, was suggested to follow a double layer model where the pairing ion occupies a primary layer at the adsorbent while the solute anion and other anions in the system comlpete for the secondary layer. Therefore, the ability of an ion pairing reagent to enhance solute adsorption depended significantly on the type and concentration of counter-ion and co-anion accompanying the ion pairing reagent or salt used for ionic strength control. In addition, a good linear relationship between the logarithm of capacity factors measured by batch and elution method as a function of the concentration of ion pairing reagent and methanol can be used to predict the retention in elution method on the basis of capacity factors measured by batch method.

• The Journal of the Korean dental association
• /
• v.47 no.9
• /
• pp.585-595
• /
• 2009

Purpose : The aim of this study was to compare surgical complications between simple implant placement and implant placement combined with complicated surgical procedures. We also evaluated prosthetic complications according to the specific types of prosthesis. Material and Method : A retrospective analysis of dental chart of patients who was performed implant therapy during the period from June 2003 to December 2005 was carried out. This study was performed on 408 patients (208 male, 200 female). In addition, 1671 implants were performed. Based on their medical record and radiographs, the authors evaluated surgical and prosthetic complications, surgical procedures accompanied at the time of implant, risk factors of implant failure etc. Result : Surgical complications were developed on 358 implants(21.4% on total placed implants) and wound dehiscence was most prevalent complication. On maxillary posterior area, surgical complications developed more frequently on implants with major surgery and showed a significant difference. And complication rate of implants accompanied with GBR was higher than that of simple implants placement and also showed significant difference. The implant supported prosthesis showed no statistical difference in the occurrence of complications according to the types of prosthesis, and food retention was the most common post-prosthetic complication. Also we speculated that length and width of implant showed significant correlation to the failure of implant primary osseointegration. Conclusion : Based on the result, clinician should provide more careful maintenance for patients with implant placement accompanied by complicated surgical procedure. And periodic maintenance for the patient is requested for long-term survival of implant therapy.

• Preventive Nutrition and Food Science
• /
• v.20 no.2
• /
• pp.126-132
• /
• 2015

This study investigated the anti-amnesic effect of fermented Ganoderma lucidum water extracts (GW) on scopolamine- induced memory impairment in rats. GW were fermented by the lactic acid bacterium Bifidobacterium bifidum (FGWB), followed by Lactobacillus sakei LI033 (FGWBL). To induce amnesia, scopolamine (1 mg/kg) was intraperitoneally injected into rats 30 min before the behavioral tests. Step-through latencies of rats treated with primary fermented extracts (300 mg/kg, FGWB) and secondary fermented extracts (300 mg/kg, FGWBL) were significantly longer than those of rats treated with GW (300 mg/kg) in the retention trial of the multiple trial passive avoidance test. In the Morris water maze task, FGWBL significantly shortened escape latencies in training trials. Furthermore, swimming times within the target zone during the probe trial with FGWBL were significantly higher than the GW and FGWB treatments. In addition, acetylcholinesterase activities were lower in the brains of scopolamine-treated rats treated with FGWBL. These results suggest that FGWBL could be useful to enhance learning memory and cognitive function via cholinergic dysfunction.

• Education of Primary School Mathematics
• /
• v.20 no.4
• /
• pp.305-319
• /
• 2017

In the process of finding the triangle height, 26 students in the 6th grade were surveyed to understand the students' triangle height through the eye movement data and to investigate the cognitive load of the students. As a result, the correctness rate of the pre-test was significantly increased in the post-test, and the frequency and retention of gaze data were smaller in the post-test than in the AOI of each question. The Participants's subjective cognitive load indicated that it was more difficult to understand the concept of rotated triangles compared with upright triangles that were parallel to the ground. More frequent and more retentions in the eye-tracking data were detected in the right triangles and acute triangles by rotating configuration. Eye movement data show that eye tracking technology can provide an objective measure of students' cognitive load for feedback on instructional design.

• Korean Journal of Environmental Agriculture
• /
• v.31 no.2
• /
• pp.113-121
• /
• 2012

BACKGROUND: The Doam watershed in Korea has been managed for the reduction and the prevention of non-point source pollution since 2007. Especially, the water quality of the Doam reservoir is a primary issue related to the Doam dam reoperation. We have carried out the modeling to evaluate the water quality based on suspended solids (SS) of the Doam watershed and the Doam reservoir. Two powerful hydrological and water quality models (HSPF and CE-QUAL-W2) were employed to simulate the combined processes of water quantity and quality both in the upland watershed of the Doam reservoir and the downstream waterbody. METHODS AND RESULTS: The HSPF model was calibrated and validated for streamflow and SS. The CE-QUAL-W2 was calibrated for water level, water temperature, and SS and was validated for the only water level owing to data lack. With the parameters obtained through the appropriate calibration, SS concentrations of inflow into and in the Doam reservoir were simulated for three years (2008, 2004 and 1998) of the minimum, the average, and the maximum of total annual precipitation during recent 30 years. The annual average SS concentrations of the inflow for 2008, 2004, and 1998 were 8.6, 10.9, and 18.4 mg/L, respectively and those in the Doam reservoir were 9.2, 13.8, and 21.5 mg/L. CONCLOUSION(s): The results showed that more intense and frequent precipitation would cause higher SS concentration and longer SS's retention in the reservoir. The HSPF and the CE-QUAL-W2 models could represent reasonably the SS from the Doam watershed and in the Doam reservoir.

• Journal of the Korean Society of Environmental Restoration Technology
• /
• v.8 no.1
• /
• pp.37-44
• /
• 2005

Nitrate($NO_3-N$) and total nitrogen(TN) removal by a reed wetland with open water(Wetland 1) was compared with that of a reed wetland without open water(Wetland 2) from March to October 2002. The two wetlands were 25mL by 6mW. An open water area, 3mL by 6mW was designed at the middle of Wetland 1. Reeds(Phragmites australis) were transplanted into the wetlands in June 2000. Water of Sinyang Stream flowing into the Kohung Estuarine Lake located in the southern part of Korea was pumped into a primary treatment pond, whose effluent was discharged into the secondary pond. Effluent from the secondary pond was funneled into the wetlands. Inflow into the wetlands averaged about 20.0$m^3$/day and their hydraulic retention time was approximately 1.5 days. Average $NO_3-N$ removal by Wetland 1 was 117.61mg/$m^2{\cdot}day$ and that by Wetland 2 was 106.39mg/$m^2{\cdot}day$. $NO_3-N$ removal efficiency of Wetland 1 and 2 was 37% and 34%, respectively. TN removal by Wetlands 1 and 2 averaged 226.80 and 214.54mg/$m^2{\cdot}day$, respectively. TN abatement efficiency of Wetland 1 was 43% and that of Wetland 2 was 40%. $NO_3-N$ removal efficiency of Wetland 1 was significantly higher(p=0.038) than Wetland 2. TN removal efficiency of Wetland 1 was also significantly higher(p=0.044) than Wetland 2. The wetland with open water was more efficient for removal of $NO_3-N$ and TN than one without.