• Child Health Nursing Research
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• 제18권2호
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• pp.68-75
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• 2012

Purpose: The purpose of this study was to measure (the degree of) injury risk perception in preschool children. Methods: The data were collected from child day care centers and kindergartens located in Seoul, and Gyeonggi and Kwangwon Province. A questionnaire consisted of 28 pictures was administered to 186 preschool children. Results: The mean score for the injury risk perception was 21.83 (${\pm}3.89$), and 77.98 converted into a 100-point scale. According to sub-categories, 'burn prevention' ($.96{\pm}.13$) was the highest, 'interpersonal safety' ($.44{\pm}.31$) was the lowest. There were significant differences in injury risk perception according to gender (t=-2.358, $p$=.019), age (t=-2.101, p=.037), experience of safety education (t=-3.719, $p$ <.001), area of residence (t=-3.445, $p$=.001), injury experience (t=3.212, $p$=.002), and mother's occupation (t=-4.858, $p$ <.001). The highest item in the percentage of correct answer item was 'making jump on the desk', the lowest item in the percentage of correct answer item was 'not wearing safety equipment when rollerblading'. Conclusion: Based on this study, studies should be continued to standardize the instrument. In addition, it is recommended that an injury prevention education program should be developed based on the results of this study to stimulate demand and interest.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6441-6446
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• 2012

Background: Radiation therapy plays an important role in lung carcinoma treatment. However, the incidence of symptomatic radiation-induced lung injury is high. This study aimed to evaluate radioprotective effects of flavonoids extracted from Astragalus complanatus and mechanisms of action against radiation damage. Methods: Alteration in antioxidant status and levles of several cytokines were investigated in BABL/C mice treated with 4 mg/kg b.wt. flavonoids after exposure to 10Gy thoracic radiation. Results: Serum levels of SOD in the flavonoids+radiation group were significantly higher compared to the radiation control group, while TGF-${\beta}1$ and IL-6 were lower. Mice in the radiation control group displayed more severe lung damage compared with the flavonoids+radiation group. The expression of TGF-${\beta}1$ and TNF-${\alpha}$ in the radiation control group was markedly increased in alveolar epithelial cells and macrophages of the alveolar septum. Conclusions: From the results of the present study, flavonoids could be excellent candidates as protective agents against radiation-induced lung injury.

• International Journal of Safety
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• 제3권1호
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• pp.47-52
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• 2004

Current OSH system was analyzed in this paper to explain why high fatal incidents and disasters are continuously repeated for recent years in Korea. It was found that we have Dichotomous Perceptional Misconception of prevention before accident and compensation after accident and there is a significant lack of proper feed­back reward system for OSH performance. It was assumed that no reduction of accident rate and fatality rate have not been achieved recently despite of a great effort and increased resource allocations. Some statistics for proving weak punishment were analyzed. In the current system, the will of administrative agency would have been very limited particularly in the legal aspects. The Industrial Safety and Health Act is not suitable to after-injury punishment for employer and/or corporate since it is based on a framework for enforcement of prevention. Based on these analyses, it was concluded that there was a need to consider a special law for Corporate Accountability for Fatal Accidents. Because it is necessary to consider seriously for introduction of a new legal system for after injury punishment to repair the current system where it was found lack of proper feedback system. Also, there was no proper sanction measures for corporate with the current OSH legal system, and the most urgent problem in OSH area is the high fatality rate. it is necessary to consider seriously for introduction of a new legal system for after injury punishment. Also, there is no proper sanction measures for corporate with the current OSH legal system, and the most urgent problem in OSH area is the high fatality rate.

• The Korean Journal of Physiology and Pharmacology
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• 제27권2호
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• pp.143-155
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• 2023

Percutaneous coronary intervention and acute coronary syndrome are both closely tied to the frequently occurring complication of coronary microembolization (CME). Resveratrol (RES) has been shown to have a substantial cardioprotective influence in a variety of cardiac diseases, though its function and potential mechanistic involvement in CME are still unclear. The forty Sprague-Dawley rats were divided into four groups randomly: CME, CME + RES (25 mg/kg), CME + RES (50 mg/kg), and sham (10 rats per group). The CME model was developed. Echocardiography, levels of myocardial injury markers in the serum, and histopathology of the myocardium were used to assess the function of the cardiac muscle. For the detection of the signaling of TLR4/MyD88/NF-κB along with the expression of pyroptosis-related molecules, ELISA, qRT-PCR, immunofluorescence, and Western blotting were used, among other techniques. The findings revealed that myocardial injury and pyroptosis occurred in the myocardium following CME, with a decreased function of cardiac, increased levels of serum myocardial injury markers, increased area of microinfarct, as well as a rise in the expression levels of pyroptosis-related molecules. In addition to this, pretreatment with resveratrol reduced the severity of myocardial injury after CME by improving cardiac dysfunction, decreasing serum myocardial injury markers, decreasing microinfarct area, and decreasing cardiomyocyte pyroptosis, primarily by blocking the signaling of TLR4/MyD88/NF-κB and also reducing the NLRP3 inflammasome activation. Resveratrol may be able to alleviate CME-induced myocardial pyroptosis and cardiac dysfunction by impeding the activation of NLRP3 inflammasome and the signaling pathway of TLR4/MyD88/NF-κB.

• 대한물리의학회지
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• 제15권3호
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• pp.1-9
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• 2020

PURPOSE: This study examined the effects of muscle fatigue on proprioception in the type of taekwondo training, causing injury to taekwondo athletes. METHODS: The subjects were divided into Taekwondo Kyorugi athletes (n = 14) and Taekwondo Poomsae athletes (n = 14). After inducing muscle fatigue to the subjects, the joint position sense (JPS) and the force reproduction sense (FRS) were measured before and immediately after the induction of muscle fatigue. RESULTS: Studies have shown no significant impact on the JPS and FRS caused by muscle fatigue induced by Poomsae and Kyorugi (p > .05). The JPS, however, showed a significant difference before and after Kyorugi (p < .05). The FRS showed significant differences before and after Poomsae (p < .05). Through this study, the injuries to taekwondo athletes appear to be influenced by the joint position and force reproduction. Moreover, the injury appears to affect the joint position sense in Kyorugi athletes and the force reproduction sense in Poomsae athletes. CONCLUSION: The results will contribute to injury prevention and athlete protection. In addition, the information can be used as basic data for the development of sports injuries prevention and rehabilitation programs for Taekwondo athletes. Research is needed on the customized management of sports methods and self-care to prevent sports damage, considering the athletic characteristics of the taekwondo athletes in the future.

• 대한안전경영과학회지
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• 제4권3호
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• pp.1-11
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• 2002

It has been Management for stabilize Enterprise-Management for Economic demand for to Productivity, Automation, customer satisfaction, Especially Semiconductor-Industry has been, potential-risk in working to factory to machine equipment, all kinds of utility, gas, chemical, electronic, Fire. This study of basic-purpose has Research Different From as Follow to analysis and Solution For semiconductor product Factory of a actual point Data and specific-gravity to Relation for company-Injury. 1. It has been try to Injury-Tendency and cause-Analysis for our County-Manufacture-Occupation. 2, Semiconductor Injury of Actual-condition in Enforcement for problem and Analysis that Injury Problem has occupated it Submitted to Solution for ordinary Injury theory View to point Solve at for New Model has applicated to that nilem for processed to Solution.

• 한국컴퓨터정보학회논문지
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• 제25권11호
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• pp.239-244
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• 2020

본 연구는 광주지역 권역응급의료센터에 내원한 환자의 의료정보를 기초로 외상의 중등도별 특성 분석을 통한 손상발생의 위험요소를 파악하여 손상예방대책을 위한 보건예방정책 제언 및 기초 자료를 마련하는데 목적이 있다. 2019년 9월 1일부터12월 31일까지 4개월간 응급의료센터에 내원한 2585명의 환자를 대상으로 손상외인 관련성을 연구의 통계학적 분석을 위하여 SPSS-Window(ver. 20.1)프로그램을 이용하였다. 연구 분석결과는 다음과 같다. 응급의료센터에 내원한 손상 환자 중 전체 2585명 환자에서 성별은 남성(61.3%)이 여성(38.7%)보다 더 많았으며, 20대에서 50대까지의 연령층에서 발생률이 높았으며 중증도를 감안하면 50대(16.8%)의 연령층이 가장 많았다(P<.001). 둘째, 중등도에 따른 손상외인의 발생장소로는 도로 및 교통지역(35.1%)이 가장 높았다(P<.001). 셋째, 중등도에 따른 손상발생의 시간은 12-18시(35.8%)로 높았다(P<.001). 넷째, 중등도에 따른 손상부위는 두부 및 안면부(55.4%)에서 가장 높았다(P<.001). 다섯째, 중등도에 따른 손상 유형은 열린상처(31.2%)에서 높았다(P<.001). 향후 손상에 대한 지속적인 관심과 연구로 외상환자 등 중증도별 특성에 따라 구체적인 보건예방정책 수립이 요구된다.

• 한국보건간호학회지
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• 제21권1호
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• pp.95-101
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• 2007

Purpose: The purpose of this study was to determine the incidence of unintentional-injury and to identify factors related to the high incidence of unintentional-injury in the community in order to provide useful data for the development of prevention and intervention programs aimed at reducing unintentional-injury incidence. Methods: This study utilized data obtained from cross-sectional national surveys conducted for the 2001 National Health and Nutrition Survey targeting 37,769 individuals aged between 0 and 99 years old, which was performed using a face-to-face interview method. Demographic characteristics, unintentional-injury experience, types of injury, and attributes of health behavior were included in the study instruments. Results: About 1.3% of the subjects had experienced unintentional injury that required hospitalization at least once during the past year. Age older than 40 years, male gender, lower education, lower income, and blue collar workers were all significantly and positively associated with increased risk of unintentional-injury. Among the health behavior variables, sleeping less than 6 hours, drunk driving, and binge drinking were significantly associated with unintentional injury, while traffic accidents and falls/slips constituted 80% of all unintentional injuries. Conclusion: Public health efforts to reduce unintentional injuries should target high-risk populations such as males, those with low income and education levels, and binge drinkers.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2405-2425
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• 2014

Radiation exposure leads to several pathophysiological conditions, including oxidative damage, inflammation and fibrosis, thereby affecting the survival of organisms. This review explores the radiation countermeasure properties of fourteen (14) plant extracts or plant-derived compounds against these cellular manifestations. It was aimed at evaluating the possible role of plants or its constituents in radiation countermeasure strategy. All the 14 plant extracts or compounds derived from it and considered in this review have shown some radioprotection in different in vivo, ex-vivo and or in vitro models of radiological injury. However, few have demonstrated advantages over the others. C. majus possessing antioxidant, anti-inflammatory and immunomodulatory effects appears to be promising in radioprotection. Its crude extracts as well as various alkaloids and flavonoids derived from it, have shown to enhance survival rate in irradiated mice. Similarly, curcumin with its antioxidant and the ability to ameliorate late effect of radiation exposure, combined with improvement in survival in experimental animal following irradiation, makes it another probable candidate against radiological injury. Furthermore, the extracts of P. hexandrum and P. kurroa in combine treatment regime, M. piperita, E. officinalis, A. sinensis, nutmeg, genistein and ginsan warrants further studies on their radioprotective potentials. However, one that has received a lot of attention is the dietary flaxseed. The scavenging ability against radiation-induced free radicals, prevention of radiation-induced lipid peroxidation, reduction in radiation cachexia, level of inflammatory cytokines and fibrosis, are some of the remarkable characteristics of flaxseed in animal models of radiation injury. While countering the harmful effects of radiation exposure, it has shown its ability to enhance survival rate in experimental animals. Further, flaxseed has been tested and found to be equally effective when administered before or after irradiation, and against low doses (${\leq}5Gy$) to the whole body or high doses (12-13.5 Gy) to the whole thorax. This is particularly relevant since apart from the possibility of using it in pre-conditioning regime in radiotherapy, it could also be used during nuclear plant leakage/accidents and radiological terrorism, which are not pre-determined scenarios. However, considering the infancy of the field of plant-based radioprotectors, all the above-mentioned plant extracts/plant-derived compounds deserves further stringent study in different models of radiation injury.

• 한국전문물리치료학회지
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• 제28권1호
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• pp.84-91
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• 2021

Background: A hip fracture may occur spontaneously prior to the hip impact, due to the muscle pulling force exceeding the strength of the femur. Objects: We conducted falling experiments with humans to measure the activity of the hip muscles, and to examine how this was affected by the fall type. Methods: Eighteen individuals fell and landed sideways on a mat, by mimicking video-captured real-life older adults' falls. Falling trials were acquired with three fall directions: forward, backward, or sideways, and with three knee positions at the time of hip impact, where the landing side knee was free of constraint, or contacted the mat or the contralateral knee. During falls, the activities of the iliopsoas (Ilio), gluteus medius (Gmed), gluteus maximus (Gmax) and adductor longus (ADDL) muscles were recorded. Outcome variables included the time to onset, activity at the time of hip impact, and timing of the peak activity with respect to the time of hip impact. Results: For Ilio, Gmed, Gmax, and ADDL, respectively, EMG onset averaged 292, 304, 350, and 248 ms after fall initiation. Timing of the peak activity averaged 106, 96, 84, and 180 ms prior to the hip impact, and activity at the time of hip impact averaged 72.3, 45.2, 64.3, and 63.4% of the peak activity. Furthermore, the outcome variables were associated with fall direction and/or knee position in all but the iliopsoas muscle. Conclusion: Our results provide insights on the hip muscle activation during a fall, which may help to understand the potential injury mechanism of the spontaneous hip fracture.