• Title/Summary/Keyword: Present Condition and Cause

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Multi-Parameter Approach for Evaluation of Genomic Instability in the Polycystic Ovary Syndrome

  • Sekar, Nishu;Nair, Manju;Francis, Glory;Kongath, Parvathy Raj;Babu, Sandhya;Raja, Sudhakaran;Gopalakrishnan, Abilash Valsala
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.7129-7138
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    • 2015
  • Background: The polycystic ovary syndrome (PCOS), characterized by hyperandrogenism and chronic anovulation, is a common endocrine disorder in women. PCOS, which is associated with polycystic ovaries, hirsutism, obesity and insulin resistance, is a leading cause of female infertility. In this condition there is an imbalance in female sex hormones. All the sequelae symptoms of PCOS gradually lead to cancer in the course of time. It is heterogeneous disorder of unknown etiology so it is essential to find the exact cause. Materials and Methods: In this study both invasive and non-invasive techniques were employed to establish the etiology. Diagnosis was based on Rotterdam criteria (hyperandrogenism, ovulatory dysfunction, PCOM) and multiparameters using buccal samples and dermatoglypic analysis and cytogenetic study for 10 cases and four age and sex matched controls. Results: In clinical analysis we have observed the mean value of total testosterone level was 23.6nmol/L, total hirsutism score was from 12-24, facial acne was found in in 70% patients with 7-12 subcapsular follicular cysts, each measuring 2-8 mm in diameter. In dermatoglypic analysis we observed increases in mean value ($45.9^{\circ}$) of ATD angle when compared with control group and also found increased frequency (38%) of Ulnar loops on both fingers (UU), (18%) whorls on the right finger and Ulnar loop on left finger (WU) and (16%) arches on right and left fingers (AA) were observed in PCOS patients when compared with control subjects. Features which could be applied as markers for PCOS patients are the presence of Ulnar loops in middle and little fingers of right and left hand. The buccal micronucleus cytome assay in exfoliated buccal cells, we found decrease in frequency of micronuclei and significant increases in frequency of karyolysed nuclei in polycystic ovarian syndrome patients. Chromosome aberration analysis revealed a significant increase in frequency of chromosome aberrations (CAs) in PCOS patients when compared with controls. Conclusions: From this present work it can be concluded that non-invasive technique like dermatoglypics analysis and buccal micronucleus cytome assays with exfoliated buccal cell can also be effective biomarkers for PCOS, along with increased CAs in lymphocytes as a sign of genetic instability. There is a hypothesis that micronuclei and chromosomal aberrations could have a predictive value for cancer. From this present work it can be concluded to some extent that non-invasive technique like dermatoglypics and buccal cell analysis can also be effective for diagnosis.

Study on the Damage Pattern Analysis of a 3 Phase 22.9/3.3kV Oil Immersed Transformer and Judgment of the Cause of Its Ignition (3상 22.9/3.3kV 유입변압기의 소손패턴 해석 및 발화원인 판정에 관한 연구)

  • Choi, Chung-Seog
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.6
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    • pp.1274-1279
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    • 2011
  • The purpose of this paper is to present the manufacturing defect and damage pattern of a 3 phase 22.9/3.3kV oil immersed transformer, as well as to present an objective basis for the prevention of a similar accident and to secure data for the settlement of PL related disputes. It was found that in order to prevent the occurrence of accidents to transformers, insulating oil analysis, thermal image measurement, and corona discharge diagnosis, etc., were performed by establishing relevant regulation. The result of analysis performed on the external appearance of a transformer to which an accident occurred, the internal insulation resistance and protection system, etc., showed that most of the analysis items were judged to be acceptable. However, it was found that the insulation characteristics between the primary winding and the enclosure, those between the ground and the secondary winding, and those between the primary and secondary windings were inappropriate due to an insulating oil leak caused by damage to the pressure relief valve. From the analysis of the acidity values measured over the past 5 years, it is thought that an increase in carbon dioxide (CO2) caused an increase in the temperature inside the transformer and the increase in the ethylene gas increased the possibility of ignition. Even though 17 years have passed since the transformer was installed, it was found that the system's design, manufacture, maintenance and management have been performed well and the insulating paper was in good condition, and that there was no trace of public access or vandalism. However, in the case of transformers to which accidents have occurred, a melted area between the upper and the intermediate bobbins of the W-phase secondary winding as well as between its intermediate and lower bobbins. It can be seen that a V-pattern was formed at the carbonized area of the transformer and that the depth of the carbonization is deeper at the upper side than the lower side. In addition, it was found that physical bending and deformation occurred inside the secondary winding due to non-uniform pressure while performing transformer winding work. Therefore, since it is obvious that the accident occurred due to a manufacturing defect (winding work defect), it is thought that the manufacturer of the transformer is responsible for the accident and that it is lawful for the manufacture to investigate and prove the concrete cause of the accident according to the Product Liability Law (PLL).

An Ethnographic Study on Middle aged Women's Hwa-Byung with Upper Limb Arthropathy (중년여성의 화병과 상지관절동통에 관한 문화기술지)

  • Kim, Mee-Young
    • Journal of East-West Nursing Research
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    • v.13 no.2
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    • pp.160-169
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    • 2007
  • Background: Hwa-Byung is known as a specific Korean cultural syndrome which corresponds to DSM-IV(MMPI). Some Korean women who have experienced heart aching anger(Hwa-Byung) complain physical pains as well as psychological problems. As for these physical pains, upper limb arthropathy(e.g. golf elbow pains, tennis elbow pains, or shoulder-joint pains) have not been paid attentions. In spite of not having done her excessive physical endeavor or exercise, some Korean middle aged women complain those arthropathy pains. And they go round orthopedics, pain clinics, and oriental medicine clinics. Purpose: This study was practiced in Severance Oriental Medicine Clinic. The oriental medicine doctor had a question about the major origin of upper limb pains which were not caused by excessive physical endeavor. To answer the question, this study has been practiced. In the process of interview with some those women, the major cause of those syndromes has been revealed as Hwa-Byung. The purpose of this study is to discover the meanings of the women's life who have been experienced Hwa-Byung with upper limb arthropathy. Results: These upper limb arthropathy can be explained by meridian theory. Shoulder-joint pain and golf elbow with Hwabyung can be explained by Heart meridian of hand-shoyin and the points of these pains are in the flow of this meridian. Tennis elbow with Hwabyung can be explained by Small intestine meridian of hand-taiyang and this point is in the flow of this meridian. The results of interview with 9 middle aged women was analyzed and interpreted according to Spradley's method of ethnography. The analysis revealed three core cultural themes : 1) There are certainly external cause to provoke Hwa-Byung. A patricentric family system, husband's playing around with another woman, cruel treatment by husband's family, or financial failure may be present anteriorly. 2) The chief existing condition is the discord between husband and wife. The stoppage of mutual communication, lacking in understanding, unfeeling, heartless, or unsympathetic is an major phenomenon of married life. So the important factor is not the sexual relations or problems but the discords of communication. 3) The feeling of anger, the sense of nihility, the desire to escape, and the effort to forgiveness coexist together. At a glance, they seemed to be a process. For example, anger seemed to present at first, then nihility seemed at second, then escape seemed at third, and then forgiveness seemed at last. But at point of visiting clinic to be treated, they are mixed up together as if in a jumble.

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Improvement Plan for Planting Large Trees in Artificial Ground of the Apartment Complex (공동주택 인공지반 대형교목 식재 개선방안)

  • Kang, Myung-Soo;Kim, Nam-Jung
    • Land and Housing Review
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    • v.6 no.4
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    • pp.221-229
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    • 2015
  • Large trees in the apartment complex are playing an important role to decide the quality of external environment. They are planted with the object of utilizing themselves as a landmark of the complex and enhancing space symbolism. Since planting large trees would require high maintenance costs and generate defect, it would cause decline in quality of external environment. This study researches on large trees in artificial ground of the apartment complex. This study analyzes actual condition of planting and tries to provide improvement direction of planting. In order to conduct this research, three target areas (over R30) and 265 trees are selected. Based on the drawings and specifications this study researches on the plan of landscape design, changes of field design, actual condition of completion, present condition of planting, minimum soil depth of growth and development and types of extra action for soil depth. The result shows that 85% of drawings and specifications for large trees in the apartment complex are deep-rooted tree species. On average large trees with R 35 are planted in artificial ground and there is lack of on average 65cm minimum soil depth of growth and development. Reviewing changes of field design is conducted in such limited size as mainly R30 and R40 and there is no extra plan for lack of soil depth. The plan for securing additional soil depth is done by 85% of mounding. However, since there is only 10% of satisfaction, the inappropriateness in securing additional soil is pointed out. This research also points out that the size of large trees, root characteristics and location-allocation for planting are pivotal factors for securing minimum soil depth of growth and development. This research also provides improvement direction in case of planning planting.

A Study on the Management and Living Environment of the Group-homes for the Elderly -Focusing on Jeonju and Kwangju- (노인그룹홈의 운영과 생활환경에 관한 연구 -전주시와 광주시를 중심으로-)

  • Ahn, Kyung-Ohn
    • Korean Journal of Human Ecology
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    • v.18 no.4
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    • pp.841-855
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    • 2009
  • The main objective of this study is to examine the situations of group-homes for the elderly and clarify the problems of them. This study investigates the present conditions of welfare facilities and supply conditions. 4 group-homes were surveyed in Jeonju and Kwangju cities. Data was collected through various ways including the survey conducted by facility operators, the measurement of living space, and photo-takings. The major results of this study are as follows: 1) With the introduction of nursing care insurance in 2008, the increase of the demand and supply to group-home will be expected, due to less cost for recuperation. The care of elderly in homelike atmosphere is effective to the elderly suffering from dementia. Therefore, it is proper that the supply of group-homes for dementia will be needed. 2) Group-homes for the elderly are being supplied under the standards of welfare facilities in the present. Separate supply standards, however, are needed because they are not suitable for small scale group-homes. 3) To supply Group-homes for the elderly on a one-unit basis would cause various problems such as economical unreality, personnel distribution and so on. It is necessary to supply more than two units for more efficient management. 4) The management of group-homes for the elderly is financially unstable because the operating funds heavily depend on the users or people who are connected with the facilities through private networks. Therefore, additional support is needed to settle the financial problem. It would be helpful to build the public networking that provides information about the group-home for the elderly for the public. 5) In case of the increase in the supply of the group-home in a residential area, it could be helpful to promote the group-home to the public. 6) The operators state that the main problems of group homes for the elderly lie in financial difficulties and the shortage of professionals and volunteers. The financial, personnel, and material support for personnel and the supervision of management are required for the transparency and effectiveness of the facility management. In addition, the closer network and cooperation system with the community is required. 7) The present living environments for group-homes for the elderly leave much room for improvement, considering the physical condition of the elderly. The more careful selections in the color, shape, material, and equipment of the facilities should be made for the convenience of the elderly users.

The Present Status Analysis of Interior Planning in a Fitness Center Inside an Apartment Complex (공동주택단지 내 휘트니스 센터 시설현황 분석에 관한 연구)

  • Cho Young-Youn
    • Korean Institute of Interior Design Journal
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    • v.14 no.4 s.51
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    • pp.87-94
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    • 2005
  • Lately due to the sudden growth of the construction of an apartment complex in domestic market, many construction companies are eager to provide various public facilities to increase the apartment distribution rate. An introduction of a fitness center is popularized as a part of such development. There has been a continuing development in a private fitness based on analyzing the user's data. However a public fitness is quite different from the private in terms of a user's classification, preference rate, the pattern of use, and location which requires a different facility plan. Nevertheless, all these days a public fitness in an apartment house has been developed without a specific facility plan based on relevant materials. It is worried that such development would cause the facilities not to function as appropriate resident facilities and sink to idle ones. Therefore the purpose of this paper is to make the standard considered in facility planning in future and the base to guide an applying method. In the paper the present condition of fitness centers inside apartment houses has been compared to analyze the progress of the existing facilities and the appropriateness of the organization and the structure division. The result of the research shows that public resident facilities is not the place to perform passive role for fixed activities but one to form a community through the human relationship based on the facility. Therefore a fitness center inside the apartment complex have to be designed to provide service and leisure space as one of main community facilities for residents. To obtain this purpose, when choosing facilities of an apartment complex, first of all the residents' standard of living, apartment size, residents' distinction rate of age and sex, the needs of the times should be fully considered Secondly, the size of each facility space have to be decided based on the practical data analysis in facility use such as space preference, average staying time. Also, future living culture requires the change of the function and space according to the change of social values, so continuing research and data analysis are required to related to fitness center inside an apartment complex in order to present systematic approaching method and the paper will be expected to be a little step toward it.

Classifying and Implementing Different Types of Contradiction Resolution Strategies in TRIZ (TRIZ에서 모순해결전략의 유형 및 적용)

  • Choi, Sungwoon
    • Journal of the Korea Safety Management & Science
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    • v.17 no.4
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    • pp.381-396
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    • 2015
  • The study proposes multiple TRIZ contradiction solution strategies for addressing PC (Physical Contradiction) and TC (Technical Contradiction) by implementing TRIZ cause-and-effect tree. The problem associated with TC of the ends is solved by PC of means which employs a causal relationship between causes and effects. The TRIZ contradiction solution strategies demonstrated in this research are classified into 3 types of combined strategy as follows: 1. To-Be PC and AS-Is PC, 2.To-Be PC and As-Is TC, 3.As-Is PC and To-Be TC. The combined strategy of To-Be PC and As-Is PC is similar to a divide-and-conquer technique. This strategy adopts parallel strategies using 4 separation principles in time, in space, between parts and the whole, and upon condition of two reversed-PCs. Moreover, its application elucidates the conflict relationship of two TCs from the study. The integrated 4 separation principles and 40 inventive principles present an effective synergy effect from the combination, and further addresses the problems in the TRIZ contradiction resolution strategies. Combined strategy of To-Be PC and As-Is TC implements the 40 inventive principles that To-Be PC of the means resolves the As-Is TC of the ends. Combined strategy of As-Is PC and To-Be TC also uses inventive principles to the As-Is PC of the means to solve the To-Be TC of the ends. In addition, propositional and logical relationship of necessary and sufficient conditions between TC and PC is used to support the validity of 3 TRIZ contradiction solution strategies. In addition, 3 other strategies of necessary and sufficient conditions validate the contraposition relationship of the truth table. This study discusses TRIZ case studies from National Quality Circle Contest from the years between 2011 and 2014 to provide the usage guidelines of TRIZ contradiction solutions for quality purposes. Examining analysis from the case studies and investigating combined strategies allows the users to obtain comprehensive understanding.

Perceptions and Attitudes of Housewives on Scalp and Hair Management (전업주부들의 두피모발 관리에 대한 인식 및 태도)

  • Kim, Myung-Woo;Kim, Sung-Nam
    • Fashion & Textile Research Journal
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    • v.9 no.3
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    • pp.336-340
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    • 2007
  • In this study, "housewives" are defined as married women who take care of housework mostly and do not work outside of home. Changing family types and higher education level of housewives enable them to be more interested in heath, beauty, and appearance. Increased interest and more frequent visits to hair salons cause scalp damage as well as hair damage, which results in hair loss. Moreover, some women suffers from scalp and hair damage due to childbirth, but many of them are not aware of it. Therefore, this study tries to find out the following; housewives' perceptions on hair and scalp management, and how such perceptions are formed. In addition, this study will present the direction for beauty marketing taking into account the characteristics of housewives and provide data necessary for them to keep their hair and scalp healthy. For these purposes, a survey was carried out after modifying the questionnaire through a presurvey. The survey tried to find 1) perceptions on hair and scalp management according to demographic characteristics, and attitude toward hair and scalp management according to demographic characteristics. Data were analyzed using frequency analysis, cross tabulation, t-test, factor analysis, and Analysis of Variance. The results were as follows, most recognize the importance of hair and scalp management but do not receive management because of the high cost, most of them receive information about hair and scalp management from people around them, and the higher the education level and health status, the more active the attitude toward hair and scalp management. These differences were all statistically significant.

Comparison of the Impact of an Optimized Ice Cooling Vest and a Paraffin Cooling Vest on Physiological and Perceptual Strain

  • zare, Mansoor;dehghan, Habibollah;yazdanirad, Saeid;khoshakhlagh, Amir hossein
    • Safety and Health at Work
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    • v.10 no.2
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    • pp.219-223
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    • 2019
  • Background: Ice cooling vests can cause tissue damage and have no flexibility. Therefore, these two undesirable properties of ice cooling vest were optimized, and the present study was aimed to compare the impact of the optimized ice cooling vest and a commercial paraffin cooling vest on physiological and perceptual strain under controlled conditions. Methods: For optimizing, hydrogel was used to increase the flexibility and a layer of the ethylene vinyl acetate foam was placed into the inside layer of packs to prevent tissue damage. Then, 15 men with an optimized ice cooling vest, with a commercial paraffin cooling vest, and without a cooling vest performed tests including exercise on a treadmill (speed of 2.8 km/hr and slope of %0) under hot ($40^{\circ}C$) and dry (40 %) condition for 60 min. The physiological strain index and skin temperature were measured every 5 and 15 minutes, respectively. The heat strain score index and perceptual strain index were also assessed every 15 minutes. Results: The mean values of the physiological and perceptual indices differed significantly between exercise with and without cooling vests (P < 0.05). However, the difference of the mean values of the indices except the value of the skin temperature during the exercises with the commercial paraffin cooling vest and the optimized ice cooling vest was not significant (P > 0.05). Conclusions: The optimized ice cooling vest was as effective as the commercial paraffin cooling vest to control the thermal strain. However, ice has a greater latent heat and less production cost.

Efficacy of Newer Molecules, Bioagents and Botanicals against Maydis Leaf Blight and Banded Leaf and Sheath Blight of Maize

  • Malik, Vinod Kumar;Singh, Manjeet;Hooda, Karambir Singh;Yadav, Naresh Kumar;Chauhan, Prashant Kumar
    • The Plant Pathology Journal
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    • v.34 no.2
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    • pp.121-125
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    • 2018
  • Maize (Zea mays L.; 2N=20) is major staple food crop grown worldwide adapted to several biotic and abiotic stresses. Maydis leaf blight (MLB) and banded leaf and sheath blight (BLSB) are serious foliar fungal diseases may cause up to 40% and 100% grain yield loss, respectively. The present studies were undertaken to work out the efficacy of chemicals, botanicals and bioagents for the management of MLB and BLSB under field condition for two seasons Kharif 2014 and 2015. Five molecules (propiconazole 25 EC, hexaconazole 25 EC, carbendazim 50 WP, mancozeb 75 WP and carbedazim 12 WP + mancozeb 63 WP), two bioagents i.e. Trichoderma harzianum and T. viridae and three botanicals namely azadirachtin, sarpagandha and bel pathar were tested for their efficacy against MLB. Eight newer fungicides viz., difenconazole 250 SC, hexaconazole 5 EC, carbendazim 50WP, validamycin 3 L, tebuconazole 250 EC, trifloxystrobin 50 WG + tebuconazole 50 WG, azoxystrobin 250 EC and pencycuron 250 SC were evaluated against BLSB. Analysis revealed significant effects of propiconazole at 0.1%, carbendazim 12 WP + mancozeb 63 WP at 0.125% and sarpagandha leaves at 10% against MLB pathogen, whereas validamycin at 0.1% and trifloxystrobin 25 WG + tebuconazole 50 WG at 0.05% were found effective against BLSB. The slow rate of disease control virtually by the bioagents might have not shown instant effect on plant response to the yield enhancing components. The identified sources of management can be used further in strengthening the plant protection in maize against MLB and BLSB.