• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 춘계학술대회
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• pp.180-180
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• 2003

Transcript profiling is a particularly valuable tool in the field of steroid receptor biology, as these receptors are ligand-activated transcription factors and therefore exert their initial effects through altering gene expression in responsive cells. Also, an increased awareness of endocrine disrupting chemicals (EBCs) and their potential to affect wildlife and humans has produced a demand for practical screening methods to identify endocrine activity. Here we developed an in-house cDNA microarray, named KISTCHIP-400, with 401 clones, hormone related genes, factors, and ESTs, based on public database and research papers. Theses clones contained estrogen, androgen, thyroid hormone St receptors, sex hormone signal transduction ＆ regulation, c-fos, c-myc, ps2 gene, metabolism related genes etc. And to validate the KISTCHIP-400, we investigated gene expression profiles with reference hormones, 10$\^$-8/ M 17be1a-estradiol, 10$\^$-7/ M testosterone, 10$\^$-7/ M progesterone, and thyroxin in MCF-7 cell line. Although it is in first step of validation, low doses and combinations of EDCs need to be tested. Our preliminary results that indicate the developed microarray may be a useful laboratory tool for screening EDCs and elucidating endocrine disrupting mechanism.

• 수산해양교육연구
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• 제27권1호
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• pp.115-124
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• 2015

The aims of this study were to validate the Occupational Basic Competencies of Fisheries and Maritime High school. Fisheries & Maritime key competencies were defined as the abilities that include the essential knowledge, skills, attitude, and experiences required for the workforce on the fisheries and maritime job condition. This research collected preliminary data from 1,113 fisheries & maritime high school students. Data were analyzed to obtain reliability and validity analysis. The results of the study were as follows; First, fisheries & maritime key competencies were divided into 6 elements. Second, fisheries & maritime key competencies were consisted of marine vocational ethics, marine information capacity, marine elementary knowlegde, marine safety management skill, management & utilization of marine life and marine consciousness. Third, Cronbach-${\alpha}$ proves that the scale developed in the study is reliable. In consequence, the results of this study help to reconceptualize fisheries & maritime and apply the scale to measure students in high school settings.

• 가정과삶의질연구
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• 제28권5호
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• pp.89-100
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• 2010

The purpose of this study was to develop a "Korean Childcare Teacher's Job Satisfaction Scale"(KCTJSS) and to evaluate its reliability and validity. KCTJSS was 72 items and 6 point Likert scale. Participants consisted of 211 childcare teachers by purposive sampling. Results were as follows: First, Exploratory factor analysis resulted in 40 items composed of 6 factors : The principal's childcare center operation system, working environments and welfare, social recognition, amount of work and time management, relationships with co-workers, relationships with parents. Second, the confirmatory factor analysis supported a 6 factor structure. Third, Criterion-related validity was confirmed by significant correlations of the present scale with Early Childhood Job Satisfaction Survey(Jorde-Bloom, 1989). Fourth, the reliability of factors using Cronbach's ${\alpha}$ appeared high, ranging from .83 to .93.

• Human Ecology Research
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• 제58권3호
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• pp.429-445
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• 2020

This study developed and validated a 'Parent-child Lexical Interaction Scale for Preschoolers (PLIS-P)'. First, we developed the preliminary scale with 7 factors after reviewing previous literature related to vocabulary and literacy instruction for young children and reflected on feedback from child studies experts and mothers with young children. Subsequently, to validate the scale, the online survey was conducted on mothers with 5-to 6-year-old children who live in Seoul, Gyeonggi, Incheon, Gyeongsang, Chungcheong, Jeolla, Gangwon, and Jeju. Responses from 309 mothers were used to conduct exploratory and confirmatory factor analysis and correlation analysis. The results were as follows. First, the result of exploratory analysis showed that the model with 7 factors was satisfactory: (1) vocabulary exposure, (2) word elaboration, (3) scaffolding, (4) play activity, (5) conventional instruction, (6) word type awareness instruction, (7) word morphology instruction. Second, confirmatory factor analysis confirmed the good fit of the model. Third, the concurrent validity was confirmed by correlation analysis using EC-HOME. Last, the internal consistency reliability of each factor of PLIS-P was also confirmed. This study developed both a theoretical framework of parent-child lexical interaction and a Parent-child Lexical Interaction Scale for Preschoolers. This scale can be used by parents, practitioners, and researchers to acquire knowledge about interaction related to words between Korean parents and young children.

• 한국보육지원학회지
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• 제12권3호
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• pp.159-176
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• 2016

The purpose of this study was to provide initial information aboutthe reliability and validity of the Korean version of the BBRS-2(Burks Behaviors Rating Scales, Second Edition). Data were collected for 217 children aged 3-5. K-BBRS-2 consists of a total of 93 questions in 7 factors. The results were as follows. First, internal consistency of the7 factors ranged from 0.81 to 0.94.Results of the confirmatory factor analysis confirmed that the 7-factor model presented in the original tool was the most appropriate. Second, children's maladaptive behavior in Korea based on K-BBRS-2 indicated evidence of validity with a meaningful correlation with children's self-esteem and peer relationships. Third Korean children's maladaptive behavior was not to have significant difference by age of children. The conclusion was that it is not necessary to calculate independent norms for age. Also, when considering gender differences, it was shown that maladaptive behavior appears more in boys than girls. K-BBRS-2 is expected to be utilized as a suitable tool for measuring the maladaptive behavior of Korean children. A nationwide standardized study for Korean children and further research with clinical groups is needed.

• 아동학회지
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• 제15권1호
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• pp.5-21
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• 1994

The purpose of this study was to develop a scale for evaluation of early childhood programs in Korea. The procedures included content validation and a pilot test. A total of 192 items in 10 major areas was developed based on the review of literature and discussions with professionals in early childhood education. The 10 areas include: scheduling, curriculum, interation, physical environment, materials, nutrition, health and safety, administration, staff qualifications, relationships with parents, and evaluation. The pilot scale was administered to 428 classroom teachers and directors, and 47 college professors in early childhood education. The items were rated on a 3-point scale in terms of importance as evaluation criteria. The methods for data analysis included item means and standard deviations for content validation, Cronbach ${\alpha}$ for reliability, and factor analysis for construct validity. Most items in 10 areas were rated as moderate to highly important (average 2.3), especially items in curriculum and staff qualifications. Two factors emerged from the data: institutional management, and curricular planning and implementation. The Cronbach ${\alpha}$ levels were .70 or higher in most areas, but the range covers from .48 to .91. Based on the pilot data, 143 items were selected for the second year study.

• 대한간호학회지
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• 제50권1호
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• pp.132-146
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• 2020

Purpose: The purpose of this study was to develop a new version of Spirituality Assessment Scale (N-SAS) and verify its reliability and validity. Methods: The total of 59 preliminary items for the N-SAS were selected through a literature review, two rounds of experts' content validation, cognitive interviews, and pre-tests. Verification of its reliability and validity was divided into two phases. In Phase I, questionnaires were collected from 219 adults. Reliability was tested using Cronbach's alpha, validity with item analysis, and exploratory factor analysis. In Phase II, questionnaires developed based on the results of Phase I were collected from 225 adults. Reliability was tested using Cronbach's alpha, validity with confirmatory factor analysis, and criterion validity. Results: The final version of the N-SAS comprised two dimensions (vertical and horizontal), four domains (relationship with God; meaning of life and self-integration; self-transcendence; and relationship with others, neighborhoods, and nature), and 44 items were identified. Total Cronbach's α was .97; those of each subscale ranged from .79 to .98. N-SAS scores were positively correlated with the scores of Howden's Spiritual Assessment Scale (r=.81, p<.001). Conclusion: Findings suggest that the N-SAS can be used to measure spirituality in adults. The use of N-SAS is expected to facilitate perceiving patient's spiritual needs and providing spiritual care.

• 말소리와 음성과학
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• 제6권2호
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• pp.133-138
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• 2014

This study attempted to investigate the validation of Phonation Threshold Power of Patients who have Functional voice disorder. 50 subjects participated in the study (32 subjects were patients who had functional voice disorders and 20 subjects were normal adults). The PAS (Phonatory aerodynamic system, model 6600, KAY electronics, Inc.) was used to measure the data and to do the analysis. Data from the Phonation Threshold Power was measured multiplying Phonation Threshold Pressure and Phonation Threshold Airflow. Phonation Threshold Pressure and Phonation Threshold Airflow were measured by the PAS protocol. Those were used because of the ease of phonation. The results of this study showed that the differences in Phonation Threshold Power between patients who had functional voice disorder and normal adults could become a significant index. Patients who had functional voice disorder showed more higher figures than normal adults. The results of study showed that Phonation threshold Power is more sensitive than Phonation Threshold Pressure and Phonation Threshold Airflow. The measured data also provided useful information for diagnosing patients with vocal fold.

• 한국보육지원학회지
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• 제18권1호
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• pp.23-50
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• 2022

Objective: The purpose of this study was to develop an early childhood teacher's autonomy scale in the implementation of the Early Childhood Curriculum and to verify its validity and reliability. Methods: A literature review and a delphi survey were conducted in order to explore conceptual characteristics and develop a preliminary questionnaire. A main survey was conducted on 375 early childhood teacher to test their item quality, validity and reliability. Results: The final scale was composed of 24 items with four factors: 'support for child-centered play environment and interaction' (7 items), 'use of learning community' (4 items), 'cooperation and participation with family and local community' (6 items), and 'flexible daily management' (7 items). And the scale was verified as a stable and reliable tool. Conclusion/Implications: This is expected to contribute to the correct understanding of children's education and to actively realize the autonomy of early childhood teachers in the implementation of the Early Childhood Curriculum.

• Nuclear Engineering and Technology
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• 제53권1호
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• pp.1-18
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• 2021

The criticality analysis of VVER-1000 mock-up benchmark experiments from the LR-0 research reactor operated by the Research Center Rez in the Czech Republic has been conducted with the MCS Monte Carlo code developed at the Computational Reactor Physics and Experiment laboratory of the Ulsan National Institute of Science and Technology. The main purpose of this work is to evaluate the newest ENDF/B-VIII.0 nuclear data library against the VVER-1000 mock-up integral experiments and to validate the criticality analysis capability of MCS for light water reactors with hexagonal fuel lattices. A preliminary code/code comparison between MCS and MCNP6 is first conducted to verify the suitability of MCS for the benchmark interpretation, then the validation against experimental data is performed with both ENDF/B-VII.1 and ENDF/B-VIII.0 libraries. The investigated experimental data comprises six experimental critical configurations and four experimental pin-by-pin power maps. The MCS and MCNP6 inputs used for the criticality analysis of the VVER-1000 mock-up are available as supplementary material of this article.