• Title/Summary/Keyword: Preferential System

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Characterization of Uridine-Diphosphate Dependent Flavonoid Glucosyltransferase from Oryza sativa

  • Hong, Byoung-Seok;Kim, Jeong-Ho;Kim, Na-Yeon;Kim, Bong-Gyu;Chong, You-Hoon;Ahn, Joong-Hoon
    • BMB Reports
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    • v.40 no.6
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    • pp.870-874
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    • 2007
  • We cloned a uridine-diphosphate dependent glycosyl-transferase RUGT-10 from Oryza sativa. The recombinant enzyme was expressed by glutathione-S transferase gene fusion system in Escherichia coli. RUGT10 showed different regioselectivity depending on the structures of substrates (e.g. flavanone, flavonol, and flavone). Apparently, flavanone such as naringenin and eriodictyol gave one 7-O-glucoside while flavone and flavonol gave more than two products with preferential glucosylation position of hydroxyl group at C-3 position.

Self-organized Nanogels of Polysaccharide Derivatives in Anti-Cancer Drug Delivery

  • Park, Sin-Jung;Na, Kun
    • Journal of Pharmaceutical Investigation
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    • v.40 no.4
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    • pp.201-212
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    • 2010
  • Self-organized nanogels from polysaccharide derivatives offer a promising approach in treatment of cancer due to their flexibility in chemistry and their ability to improve the therapeutic index of a drug by modifying biodistribution by their preferential localization at target sites and lower distribution in normal healthy tissues. These properties have promoted studies of active cancer targeting by self-organized nanogels for even better accumulation in solid tumors. However although many researchers have reported their potential by using cell culture systems and small animal tumor models in cancer therapy, these nanogels need more decoration such as conjugation with targeting moiety and endowment of stimuli-sensitivity for precise targeting of the cancer site. In this review, we summarize the recent efforts in developing novel targeting approaches via active endocytosis and stimuli-sensitive systems responding to hyperthermic or acidic tumor pH conditions.

Surface and Interface Analysis with Medium Energy Ion Scattering Spectroscoppy

  • Moon, Dae-Wom
    • Proceedings of the Korean Vacuum Society Conference
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    • 1998.02a
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    • pp.129-129
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    • 1998
  • Most of the surface/interface analysis tools have limited depth profiling c capability in terms of the profiling range and the depth resolution. However, M MEIS can profile the surface and subsurface composition and structure q quantitatively and non-destructively with atomic layer depth resolution. I In this presentation, the MEIS system developed at KRISS will be briefly d described with an introduction on the principle of MEIS. Recent MEIS r results on the surface and interface composition and structural change due to i ion bombardment will be presented for preferential sputtering of T:없Os and d damage depth profiles of SHooD, Pt(l11), and Cu(l1D due to Ar+ ion b bombardment. Direct observation of strained Si lattices and its distribution i in the SHool)-SiCh interface and the initial stage of Co growth on Pt(l11) w will be reported. H surfactant effects on epitaxial growth of Ge on Si(ooD w will be discussed with STM results from SND.

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Enantiospecific Membrane Processes

  • Giorno, Lidietta
    • Korean Membrane Journal
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    • v.1 no.1
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    • pp.38-42
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    • 1999
  • Membrane technology can be applied in two ways to produce pure enantiomers. In one case a membrane separation process can be cmbined with an enantiospecific reaction to obtain so-called 'en-antiospecific membrane reacto' These systems are useful to carry out asymmetric synthesis or kinetic resolution and simulatneously separate the produced enantiomer. As for general membrane reactors the result is a more compact system with a higher conversion: in fact removal of a product drives equilibrium-limited reactions towards completion. The other way to apply membrane technology to chiral production is the use of intrinsically enantioselective membranes that are able to distinguish between two isomers favouring preferential transport of only one isomer in absence of reaction. In this paper the current development of chiral membrane processes will be discussed.

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Properties of ZnO:Ga Thin Films Deposited by RF Magnetron Sputtering with Ar Gas Flows (RF 마그네트론 스퍼터링법으로 제조한 GZO 박막의 Ar 유량에 따른 특성)

  • Kim, Deok Kyu
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.33 no.6
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    • pp.450-453
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    • 2020
  • In this study, ZnO:Ga thin films were fabricated on a glass substrate using various Ar flows by an RF magnetron sputter system at room temperature. The dependencies of Ar flow on different properties were investigated. An appropriate control over the Ar flow led to the formation of a high-quality thin film. The ZnO:Ga films were formed as a hexagonal wurtzite structure with high (002) preferential orientation. The films exhibited a typical columnar microstructure and a smooth top face. The average transmittance was 85~89% within the visible area. By decreasing the Ar flow, the sheet resistance was decreased due to an increase in the grain size and a decrease in the root mean square roughness. The lowest sheet resistance of 86 Ω/□ was obtained at room temperature for the 40 sccm Ar flow.

Design of a MAC protocol for the communication of semiconductor equipments (반도체 장비 간 통신을 위한 센서네트워크 MAC 프로토콜 설계)

  • Lee, Eunyoung;Gao, Xiang;Jeong, Seung-heui;Oh, Chang-heon;Park, Hyung-Kun
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.05a
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    • pp.749-751
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    • 2009
  • In this paper, we designed a sensor network using zigbee for controlling and monitoring semiconductor equipments. Unlike general kinds of sensor networks, it is important to preferential send emergency data to the control server. Therefore, we proposed a MAC protocol which consider the priority for the urgency data handling.

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Substrate specificity of bacterial endoribonuclease toxins

  • Han, Yoontak;Lee, Eun-Jin
    • BMB Reports
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    • v.53 no.12
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    • pp.611-621
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    • 2020
  • Bacterial endoribonuclease toxins belong to a protein family that inhibits bacterial growth by degrading mRNA or rRNA sequences. The toxin genes are organized in pairs with its cognate antitoxins in the chromosome and thus the activities of the toxins are antagonized by antitoxin proteins or RNAs during active translation. In response to a variety of cellular stresses, the endoribonuclease toxins appear to be released from antitoxin molecules via proteolytic cleavage of antitoxin proteins or preferential degradation of antitoxin RNAs and cleave a diverse range of mRNA or rRNA sequences in a sequence-specific or codon-specific manner, resulting in various biological phenomena such as antibiotic tolerance and persister cell formation. Given that substrate specificity of each endoribonuclease toxin is determined by its structure and the composition of active site residues, we summarize the biology, structure, and substrate specificity of the updated bacterial endoribonuclease toxins.

A Study on Methodology of Self-determination of HS Commodity Classification for Utilizing FTA Preferential Tariff of SMEs (중소기업의 FTA 특혜활용을 위한 HS 품목분류 자가결정 방법에 대한 연구)

  • Kim, Young-Chun;Ryu, Geun-Woo;Lee, Ju-Young
    • International Commerce and Information Review
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    • v.16 no.1
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    • pp.91-116
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    • 2014
  • This study reviews the methodology for utilizing information technology by which even non-professionalists in FTAs and commodity classification area can perform the determination of commodity classification, with ease and by themselves, by means of easy utilization of the information on commodity classification and FTAs, of importing and exporting goods. This article examines the technological elements and logics, etc. which simulate the commodity classification for utilizing FTAs. To achieve this, the author has developed the technology to support the determination of commodity classification numbers by accumulating the database of examples for classification after analyzing the classification factors by each commodity item. Utilizing this Commodity Classification Determination Supporting System, users can enjoy effects of education as well as consulting. In this regards, the advantages of this system can be enumerated as followings : Firstly, self-checking on commodity classification can be performed. Secondly, time and cost for classification can be saved. Thirdly, comprehensive competitiveness will be enhanced by allowing traders to achieve the benefit of FTA preferential tariff, for they will be able to issue the Certificate of Origins on a more accurate and precise basis of commodity classification.

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'The Effectiveness Analysis for Bus Management Systems' (버스운행관리시스템 효과분석 (대구시 BMS를 대상으로))

  • Oh, Young-Tae;Lee, Gun-Sang;Ha, Dong-Ik;Kang, Ji-Hoon
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.5 no.2 s.10
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    • pp.44-54
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    • 2006
  • The share rate of bus mode has been decreasing continuously. To solve this problem, the local governments implement Bus Management System(BMS) or Bus Impormation System(BIS). In operating the public transportation preferential policy, it is very important to verify the effectiveness of the projects. This study performed the effectiveness of BMS through before and after study based on the field data. Moreover, this study analyzed the factors affecting to BMS. We anticipate that the results of this study would be useful reference in local government's BMS planning.

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Designing for a system of multi level spatial database abstraction (공간데이터베이스 다중 추상화시스템 구축에 관한 연구)

  • 최병남
    • Spatial Information Research
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    • v.10 no.3
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    • pp.421-438
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    • 2002
  • Abstraction of geographic data within a spatial database context must deal with geometrical simplification, modification or maintenance of the integrity of features, spatial and aspatial data, topology within class, and relationships between classes. This research is to propose a method to abstract a spatial database into a high level database. This study refines operators to carry out the modifications required by the abstraction process in the spatial database. Then, a set of operator sequences (workflows) is suggested to specify operators required to abstract a given feature class and to arrange them in order. Finally, a prototype system is developed, based on rule management with a graphic user interface. When the abstraction process is implemented sequentially we demonstrate that a preferential ordering of operations improves efficiency and reduces loss and distortion in the information.

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