• Title/Summary/Keyword: Pre-injection

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Optimization of Multiple Quality Characteristics for Polyether Ether Ketone Injection Molding Process

  • Kuo Chung-Feng Jeffrey;Su Te-Li
    • Fibers and Polymers
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    • v.7 no.4
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    • pp.404-413
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    • 2006
  • This study examines multiple quality optimization of the injection molding for Polyether Ether Ketone (PEEK). It also looks into the dimensional deviation and strength of screws that are reduced and improved for the molding quality, respectively. This study applies the Taguchi method to cut down on the number of experiments and combines grey relational analysis to determine the optimal processing parameters for multiple quality characteristics. The quality characteristics of this experiment are the screws' outer diameter, tensile strength and twisting strength. First, one should determine the processing parameters that may affect the injection molding with the $L_{18}(2^1{\times}3^7)$ orthogonal, including mold temperature, pre-plasticity amount, injection pressure, injection speed, screw speed, packing pressure, packing time and cooling time. Then, the grey relational analysis, whose response table and response graph indicate the optimum processing parameters for multiple quality characteristics, is applied to resolve this drawback. The Taguchi method only takes a single quality characteristic into consideration. Finally, a processing parameter prediction system is established by using the back-propagation neural network. The percentage errors all fall within 2%, between the predicted values and the target values. This reveals that the prediction system established in this study produces excellent results.

The Study of Combined Voice Therapy with Intralaryngeal Injection (성대주입술을 결합한 음성치료의 효과 연구)

  • Ahn, Cheol Min;Jung, Hwa Won;Shin, Jung Eun
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.28 no.1
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    • pp.25-31
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    • 2017
  • Background and Objectives : Though voice therapy is proven to be effective in academia, treatment results and satisfaction level are inconsistent in clinics. The inconsistency may rise from diverse vocal cords misuse patterns in patient population as they suffer from different diseases or have bad phonation habits. In order to overcome the limitation, we uniformized patients' vocal cords with injection laryngoplasty prior to voice therapy. The efficacy of voice therapy and consistency in treatment results after injection laryngoplasty were assessed. Materials and Methods : Patients diagnosed with vocal nodules were either treated with injection laryngoplasty followed by voice therapy (combined treatment group) or voice therapy only (voice therapy group). Each group consisted of 15 patients. Acoustic measures (jitter, shimmer, NHR), aerodynamic measures (MPT, Psub, MAFR), and subjective auditory conscious measures (K-VHI, K-VRQOL) between two groups were analyzed. Results : After treatments, both groups improved in terms of acoustic, aerodynamic, and subjective auditory conscious measures compared to pre-treatment. Combined treatment group had statistically significantly greater improvement in shimmer, P in K-VHI, and PF in K-VRQOL compared to voice therapy group. Conclusion : Injection laryngoplasty treatment prior to voice therapy synergizes in treating patients compared to voice therapy only.

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Effect of the Timing of Oocyte Activation on Development of Rat Somatic Cell Nuclear Transfer Embryos

  • Roh, Sang-Ho
    • Reproductive and Developmental Biology
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    • v.29 no.4
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    • pp.229-234
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    • 2005
  • Methods for activation of reconstructed oocytes were examined for the production of nuclear transfer (NT) rat embryos using fetal neural stem cells as donor. Neural stem cells were isolated from Day 14.5 rat fetuses, and the oocytes for recipient cytoplasm were recovered from 4-week old Sprague Dawley rats. After enucleation and nuclear injection, the reconstructed oocytes were immediately exposed to activation medium consisting of 10 mM $SrCl_2$ for 4 h (immediate activation after injection; IAI), or cultured in vitro for $2\~3$ h before activation treatment (injection before activation; IBA). Pre-activated oocytes were also used for NT to test reprogramming potential of artificially activated oocytes. The oocytes were grouped as IIA (immediate injection after activation) and ABI (activation $2\~3$ h before injection). Following NT, the oocytes were cultured in vitro. Development of the NT embryos was monitored at 44 and 119 h after activation. The embryos in groups IAI, mA, and IIA were cleaved to the 2-cell stage at the rates of $36.6\%\;(15/41),\;39.5\%\;(17/43)\;and\;46.3\%$ (25/54), respectively. However, in the ABI group, only one embryo ($1.8\%$, 1/55) was cleaved after activation. After in vitro culture, two NT embryos from IAI group had developed to the morula stage $(4.9\%\cdot2/41)$. However, no morula or blastocyst was obtained in the other groups. These results suggest that immediate activation after injection (IAI) method may be used for the production of rat somatic cell NT embryos.

Clinical outcome of ultrasound-guided atelocollagen injection for patients with partial rotator cuff tear in an outpatient clinic: a preliminary study

  • Chae, Sang Hoon;Won, Jae Yeon;Yoo, Jae Chul
    • Clinics in Shoulder and Elbow
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    • v.23 no.2
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    • pp.80-85
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    • 2020
  • Background: Atelocollagen has been studied for restoration of rotator cuff tendon. In this study, we attempted to evaluate the clinical outcome of ultrasound-guided atelocollagen injection in an outpatient clinic for patients with partial rotator cuff tear. Methods: We recruited 42 outpatients who visited our hospital from May 2019 to September 2019. Atelocollagen injection was performed in patients with partial rotator cuff tear diagnosed by magnetic resonance imaging and ultrasound. American Shoulder and Elbow Surgeons (ASES), Constant, Korean Shoulder Score (KSS) and Simple Shoulder Test (SST) scores, and range of motion were assessed before injection and after 2 months. Statistically, we analyzed the clinical results using the Wilcoxon signed-rank test. Results: Finally, 15 patients were enrolled for analysis. There was no significant difference between pre- and post-injection in terms of range of motion, ASES (57.0 vs. 60.4), Constant (56.4 vs. 58.9), KSS (64.6 vs. 68.5), and pain-visual analog scale (4.2 vs. 3.7), except function-visual analog scale (F-VAS; 6.3 vs. 7.1) and SST (6.6 vs. 6.9). A significant difference was found in SST (P=0.046) and F-VAS (P=0.009). According to the ultrasound results at 2 months, we found hyperechoic materials in three of seven patients. The most common complication of atelocollagen injection was post-injection pain (53%, 8/15). Conclusions: Ultrasound-guided atelocollagen injection for partial rotator cuff tear showed no significant change in terms of clinical outcomes, except for F-vas and SST score. Tendon regeneration was not clear due to the remnants of atelocollagen present at 2-month follow-up ultrasound. There seems to be alarming post-injection pain for 2 to 3 days in the patients who received atelocollagen injection in an outpatient clinic.

Effects of Remote Ischemic Pre-Conditioning to Prevent Contrast-Induced Nephropathy after Intravenous Contrast Medium Injection: A Randomized Controlled Trial

  • Dihia Belabbas;Caroline Koch;Segolene Chaudru;Mathieu Lederlin;Bruno Laviolle;Estelle Le Pabic;Dominique Boulmier;Jean-Francois Heautot;Guillaume Mahe
    • Korean Journal of Radiology
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    • v.21 no.11
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    • pp.1230-1238
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    • 2020
  • Objective: We aimed to assess the effects of remote ischemic pre-conditioning (RIPC) on the incidence of contrast-induced nephropathy (CIN) after an intravenous (IV) or intra-arterial injection of contrast medium (CM) in patient and control groups. Materials and Methods: This prospective, randomized, single-blinded, controlled trial included 26 patients who were hospitalized for the evaluation of the feasibility of transcatheter aortic valve implantation and underwent investigations including contrast-enhanced computed tomography (CT), with Mehran risk scores greater than or equal to six. All the patients underwent four cycles of five minute-blood pressure cuff inflation followed by five minutes of total deflation. In the RIPC group (n = 13), the cuff was inflated to 50 mm Hg above the patient's systolic blood pressure (SBP); in the control group (n = 13), it was inflated to 10 mm Hg below the patient's SBP. The primary endpoint was the occurrence of CIN. Additionally, variation in the serum levels of cystatin C was assessed. Results: One case of CIN was observed in the control group, whereas no cases were detected in the RIPC group (p = 0.48, analysis of 25 patients). Mean creatinine values at the baseline, 24 hours after injection of CM, and 48 hours after injection of CM were 88 ± 32 μmol/L, 91 ± 28 μmol/L and 82 ± 29 μmol/L, respectively (p = 0.73) in the RIPC group, whereas in the control group, they were 100 ± 36 μmol/L, 110 ± 36 μmol/L, and 105 ± 34 μmol/L, respectively (p = 0.78). Cystatin C values (median [Q1, Q3]) at the baseline, 24 hours after injection of CM, and 48 hours after injection of CM were 1.10 [1.08, 1.18] mg/L, 1.17 [0.97, 1.35] mg/L, and 1.12 [0.99, 1.24] mg/L, respectively (p = 0.88) in the RIPC group, whereas they were 1.11 [0.97, 1.28] mg/L, 1.13 [1.08, 1.25] mg/L, and 1.16 [1.03, 1.31] mg/L, respectively (p = 0.93), in the control group. Conclusion: The risk of CIN after an IV injection of CM is very low in patients with Mehran risk score greater than or equal to six and even in the patients who are unable to receive preventive hyperhydration. Hence, the Mehran risk score may not be an appropriate method for the estimation of the risk of CIN after IV CM injection.

Scenario Analysis of Injection Temperature and Injection Rate for Assessing the Geomechanical Stability of CCS (Carbon Capture and Sequestration) System (이산화탄소 격리저장시스템의 역학적 안정성 평가를 위한 주입온도 및 주입량 시나리오 해석)

  • Kim, A-Ram;Kim, Hyung-Mok
    • Tunnel and Underground Space
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    • v.26 no.1
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    • pp.12-23
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    • 2016
  • For a successful accomplishment of Carbon Capture Sequestration (CCS) projects, appropriate injection conditions should be designed and optimized for site specific geological conditions. In this study, we evaluated the effect of injection conditions such as injection temperature and injection rate on the geomechanical stability of CCS system in terms of TOUGH-FLAC simulator, which is one of the well-known T-H-M coupled analysis methods. The stability of the storage system was assessed by a shear slip potential of the pre-existing fractures both in a reservoir and caprock, expressed by mobilized friction angle and Mohr stress circle. We demonstrated that no tensile fracturing was induced even in the cold CO2 injection, where the injected CO2 temperature is much lower than that of the reservoir and tensile thermal stress is generated, but shear slip of the fractures in the reservoir may occur. We also conducted a scenario analysis by varying injected CO2 volume per unit time, and found out that it was when the injection rate was decreasing in a step-wise that showed the least potential of a shear slip.

Design and Implementation of Advanced Web Log Preprocess Algorithm for Rule based Web IDS (룰 기반 웹 IDS 시스템을 위한 효율적인 웹 로그 전처리 기법 설계 및 구현)

  • Lee, Hyung-Woo
    • Journal of Internet Computing and Services
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    • v.9 no.5
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    • pp.23-34
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    • 2008
  • The number of web service user is increasing steadily as web-based service is offered in various form. But, web service has a vulnerability such as SQL Injection, Parameter Injection and DoS attack. Therefore, it is required for us to develop Web IDS system and additionally to offer Rule-base intrusion detection/response mechanism against those attacks. However, existing Web IDS system didn't correspond properly on recent web attack mechanism because they didn't including suitable pre-processing procedure on huge web log data. Therfore, we propose an efficient web log pre-processing mechanism for enhancing rule based detection and improving the performance of web IDS base attack response system. Proposed algorithm provides both a field unit parsing and a duplicated string elimination procedure on web log data. And it is also possible for us to construct improved web IDS system.

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Systematic Review on the efficiency of prefilled syringe : To administer medication for cardiac arrest patient

  • Yoon, Byoung Gil;Park, Jung Hee;Kim, Young Seo
    • International Journal of Advanced Culture Technology
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    • v.10 no.4
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    • pp.23-244
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    • 2022
  • The Pulpose of this systematic review is aimed to establish the procedure of the injection with saftey and efficiency in the pre-hospital cardiac arrest patient performing the cardiopulmonary resuscitation (CPR), compared with traditional medication administration using Ampoule and medication administration with Prefilled Syringe. Databases were searched for CPR, heart arrest, resuscitation, Pre-filled Syringe, and Ampoule by the electronic data research including Pubmed, EMBASE and Cochran Library of Konyang University Library: 4 articles were selected by three co-authors using EndNote X20 and Covidence (Covidence.org) and were systematically reviewed. The Result of this study, the medication administration using Pre-fillled Syringe improves the safety of patients and Emergency medical workers by reducing the error in administration dose and administering the drug in safe than the medication adminisrtaion using Ampoule, also, contributes to the increment of survival rate of cardiac arrest and severe patients by decreasing the administration time that prevents the delay of medication administration.

Numerical Analysis of Effects of Water Mist Injection Characteristics on Cooling Performance in Heated Chamber (미분무수 분사 특성에 따른 가열 챔버 내 냉각 성능 수치 해석)

  • Sumon, S.M.;Lee, S.W.
    • Journal of ILASS-Korea
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    • v.17 no.2
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    • pp.64-70
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    • 2012
  • Water mist fire suppression systems which use relatively small droplets of water with high injection pressure are increasingly being used in wider applications because of its greater efficiency, low flooding damage and low toxicity. However, the performance of the system significantly relies on the water mist characteristics and it requires better understanding of fire suppression mechanism of water mist. In the present study, computational fluid dynamics simulations were carried out to investigate cooling performance of water mist in heated chamber. The gas phase was prepared with natural convection heat transfer model for incompressible ideal case and then the effects of water mist injection characteristics on cooling capabilities were investigated upon the basis of the pre-determined temperature field. For the simulation of water mist behavior, Lagrangian discrete phase model was employed by using a commercial code, FLUENT. Smaller droplet sizes, greater injection angles and higher flow rates provided relatively higher cooling performance.

A Study on Ignition Probability and Combustion Characteristics of Low Pressure Direct Injection LPG according to a Function of Ambient Condition (분위기 조건 변화에 따른 저압 직접분사식 LPG의 점화성 및 연소특성 연구)

  • Chung, Sung-Sik;Hwang, Seong-Ill;Yeom, Jeong-Kuk;Jeon, Byong-Yeul
    • Journal of Power System Engineering
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    • v.20 no.2
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    • pp.32-42
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    • 2016
  • Under part load condition of spark-ignition engine, pumping loss had great effect on engine efficiency. To reduce pumping loss, the study designed spark-ignited engines to make direct spray of gasoline to combustion chamber. In spark-ignited direct-injection engines, ignition probability is important for successful combustion and flame propagation characteristics are also different from pre-mixed combustion. This study designed a visualization testing device to study ignition probability of spark-ignited direct-injection LPG fuel and combustion flame characteristics. This visualization device consists of combustion chamber, fuel supply system, air supply system, electronic control system and data acquisition system. Ambient pressure, ambient temperature and ambient air flow velocity are important parameters on ignition probability of LPG-air mixture and flame propagation characteristics, and the study also found that sprayed LPG fuel can be directly ignited by spark-plug under proper ambient conditions. To all successful cases of ignition, the study recorded flame propagation image in digital method through ICCD camera and its flame propagation characteristics were analyzed.