• 대한통합의학회지
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• 제11권1호
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• pp.63-70
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• 2023

Purpose : Excessive alcohol causes damage to skeletal muscles, leading to the development of a specific disease entity called alcoholic myopathy. Chronic inflammation is related as an underlying mechanism for the loss of muscle mass induced by alcohol. Pro-inflammatory cytokines such as TNF-α (tumor necrosis factor-α) and IL-6 (interleukin-6) play a role in this process. The acupuncture point Feng Shi (GB 31) is located on the midline of the lateral aspect of the thigh, above the transverse popliteal crease. This acupoint is used for the treatment of weakness, atrophy, numbness, and post-stroke symptoms of lower limbs. The purpose of this study was to investigate the effect of Feng Shi stimulation on muscle atrophy caused by chronic alcohol administration. Method : Young male Sprague-Dawley rats were randomly divided into three groups of eight each: Normal, Control, and GB31. The rats in the Control and GB31 groups were orally given 25 % ethanol (5 ㎖/kg, body weight) daily for 4 weeks. The Normal group was similarly administered saline. The acupressure at Feng Shi was treated to rats in the GB31 group. After 4 weeks, the body weight, muscle weight and cross-sectional area of gastrocnemius were assessed and the histological changes in gastrocnemius muscle fiber were observed by hematoxylin and eosin staining. Moreover, TNF-α and IL-6 expressions were immunohistochemistrically evaluated. Results : Acupressure stimulation at Feng Shi had a protective effect on the weight reduction of the gastrocnemius muscle caused by alcohol intake, and had an effect of suppressing anatomical change in muscle fiber and decreasing the average cross-sectional area. Also, the immunoreactivities of TNF-α and IL-6 in the GB31 group were decreased. Conclusion : These results suggest that acupressure at Feng Shi has protective effects on chronic alcohol-induced muscle atrophy by inhibiting pre-inflammatory proteins such as TNF-α and IL-6.

• 산업융합연구
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• 제20권12호
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• pp.235-244
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• 2022

연구목적: 본 연구는 플립러닝과 디자인씽킹 교수법을 적용한 간호과정 교육 프로그램을 개발하고, 프로그램이 간호학생의 학습자기효능감, 문제해결능력, 공감, 학습만족도에 미치는 효과를 확인하고자 한다. 연구방법: 기본간호학을 수강하는 학생을 대상으로 하는 단일군 사전사후 원시 실험설계에 의한 실험연구이다. 플립러닝과 디자인씽킹 교수학습법을 적용하여 교육 프로그램을 개발하였고, 최종 41명의 간호학생을 대상으로 하여 학습자기효능감, 문제해결능력, 공감, 학습만족도를 분석하였다. 분석결과: 교육 프로그램의 효과로 학습자기효능감(t=-2.11, p=.041), 문제해결능력(t=-2.11, p=.042), 학습만족도(t=-6.40, p<.001)에서 통계적으로 유의한 차이가 있었다. 공감은 교육 전‧후에 통계적으로 유의한 차이가 없었으나 하부요인 중 관점취하기가 교육 전 24.56점에서 25.41점으로 유의하게 증가하였다(t=-2.11, p=.041). 결론: 본 연구결과를 바탕으로 간호학생에 대한 다양한 교수학습법 적용 교육 프로그램 개발을 제언한다.

• 한국체육학회지인문사회과학편
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• 제54권4호
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• pp.347-361
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• 2015

본 연구는 프로구단을 활용한 기업의 스포츠마케팅 전략이 기업이미지의 변화 및 설득을 이끌어낼 수 있는지 알아보는데 연구의 목적이 있다. 특히, 기업이미지의 설득과정에서 원산지와 기업평판이 기업이미지변화에 어떠한 조절효과가 있는지 분석하고자 하였다. 이에 사전·사후의 실험을 통해 최종적으로 211명의 유효자료를 확보하였고, 기업 이미지 변화와 원산지 인식 및 기업평판의 조절효과를 분석하여 다음과 같은 결론을 얻었다. 첫째, 실험 후 기업의 신뢰이미지와 사회공헌이미지는 통계적으로 유의한 증가를 보였다. 둘째, 원산지 인식에 따라 기업이미지는 실험 전·후 차이를 보였으며, 실험 후 기업의 신뢰이미지와 사회공헌이미지는 증가하였다. 셋째, 기업평판에 따라 기업이미지는 실험 전·후 차이를 보였으며, 실험 후 기업의 신뢰이미지와 사회공헌이미지는 증가하였고, 신뢰이미지에서는 기업평판에 따른 조절효과가 확인되었다. 종합해보면 본 연구는 프로구단을 활용한 기업의 스포츠마케팅 전략이 기업이미지의 설득에 영향을 미친다는 연구결과를 보여주고 있으며, 동시에 소비자로부터 기업이미지를 변화시키는 중요한 마케팅도구임을 증명해주고 있다.

• 한국환경농학회지
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• 제42권2호
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• pp.131-138
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• 2023

The biological half-life and dissipation rate of azoxystrobin in crown daisy were calculated to establish the pre-harvest residue limits (PHRLs). The pesticide residues were calculated after washing with five different processes to propose an effective process in the household and conducted a risk assessment to confirm dietary safety. Azoxystrobin was sprayed according to the critical good agricultural practices (cGAP) in two different field trials, and the samples were harvested 7 times. The limit of quantitation was 0.02 mg/kg, and the mean recoveries of azoxystrobin were within the range of 70~120% with below 20% coefficient variation at the concentration of 0.02 and 0.2 mg/kg . The biological half-lives were 7.4 and 4.7 days, and the dissipation rate constants were 0.0872 and 0.1217 in fields 1 and 2, respectively. The average removal rates were 58.13~78.13% by the different washing processes, and there were significant differences between the washing processes (one-way ANOVA analysis and post-hoc Duncan test, p-value<0.05). The residues of azoxystrobin in crown daisy were safe levels from farm to fork after application with the critical good agricultural practice (cGAP) registered in Korea.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.923-928
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• 2022

Wildfire disasters in the United States impact lives and livelihoods by destroying private homes, businesses, community facilities, and infrastructure. Disaster victims suffer from damaged houses, inadequate shelters, inoperable civil infrastructure, and homelessness coupled with long-term recovery and reconstruction processes. Cities and their neighboring communities require an enormous commitment for a full recovery for as long as disaster recovery processes last. State, county, and municipal governments inherently have the responsibility to establish and provide governance and public services for the benefit and well being of community members. Municipal governments' comprehensive and emergency response plans are the artifacts of planning efforts that guide accomplishing those duties. Typically these plans include preparation and response to natural disasters, including wildfires. The standard wildfire planning includes and outlines (1) a wildfire hazard assessment, (2) response approaches to prevent human injury and minimize damage to physical property, and (3) near- and long-term recovery and reconstruction efforts. There is often a high level of detail in the assessment section, but the level of detail and specificity significantly lessons to general approaches in the long-term recovery subsection. This paper aims to document the extent of wildfire preparedness at the county level in general, focusing on the long-term recovery subsections of municipal plans. Based on the identified challenges, the researchers provide recommendations for better longer-term recovery and reconstruction opportunities: 1) building permit requirements, 2) exploration of the use of modular construction, 3) address through relief from legislative requirements, and 4) early, simple, funding, and the aid application process.

• 인터넷정보학회논문지
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• 제24권6호
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• pp.99-105
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• 2023

4차 산업혁명 시대의 흐름에 발맞춰 형사사법 분야에서는 효율적인 법률서비스 제공을 위해 인공지능을 활용한 리걸테크(Legaltech)에 주목하고 있다. 본 논문은 국내 형사사법 분야의 리걸테크 활용 가능성을 증대시키기 위해 순환신경망(RNN)을 적용할 수 있는 범죄 예측 모델을 제시한다. 이를 위하여 판결문상 기술된 범죄사실에 기반하여 스크립트 분석기법 활용을 통해 범행 과정을 전·중·후 단계로 구분하였다. 또한, 각 시점에 따라 범죄의 수법과 증거 등을 수사 8하원칙이 가지는 문장 구성 요소와 한국어 품사 구성에 기반하여 객체·행위·환경으로 분류하였다. 이 연구에서 도출된 사건 요약 분석 틀은 특정 범죄 수법의 전형적인 패턴을 파악하기에 용이하며 상황적 범죄예방 전략을 수립하는데 기여할 수 있다. 나아가 이 연구의 결과는 향후 후속연구에서의 RNN모델 기반 범죄 상황 예측 데이터 생성 연구에 유용한 참고자료로 활용될 수 있을 것이다.

• 동의신경정신과학회지
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• 제35권2호
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• pp.177-189
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• 2024

Objectives: This study aimed to evaluate the impact of Resource Mindfulness on participants' emotional state, focusing on anxiety and stress reduction and to explore the importance of psychological resources in this process. The effectiveness of Resource Mindfulness was investigated through both quantitative and qualitative analyses, examining its influence on subjective distress, mindfulness, core emotions, and identification of personal resources. Methods: This study involved 27 participants, including Korean medicine students, psychological counselors, clinical psychologists, and Korean medicine specialists, who attended a 2-night, 3-day M&L psychological support education program from July 2 to July 4, 2022. Participants were informed of the study's purpose and procedures. They provided written consent. Quantitative measures included Subjective Units of Disturbance Scale (SUDS), Five Facet Mindfulness Questionnaire (FFMQ), and Core Seven-Emotions Inventory Short Form (CSEI-s). Qualitative analysis was conducted using the "Drawing the Rooms of the Mind" technique. Pre- and post-program assessments were conducted to compare changes in subjective distress, mindfulness, and core emotions. Data were analyzed using paired t-tests and qualitative content analysis methods. Results: Significant reductions in subjective distress and improvements in mindfulness components were observed. Core emotions showed significant decreases in negative emotions. Qualitative analysis revealed increased tranquility, relief, and confidence, with resourceful places often being nature-related. Conclusions: Resource Mindfulness effectively reduced anxiety and stress and enhanced self-awareness and self-efficacy. It is useful for managing various mental health issues. Further research is needed to generalize these findings.

• 한국산업보건학회지
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• 제34권2호
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• pp.125-133
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• 2024

Objectives: The aim of this study is to develop a comprehensive Occupational Safety and Health (OSH) guide for maintenance tasks in semiconductor processing, specifically focusing on etching, deposition, and ion implantation processes. Methods: The development of the OSH guide involved a literature review, consultations with industry experts, and field investigations. It concentrates on Maintenance Work (MW) operations in these specialized areas. Results: The result is a detailed OSH guide tailored to MW in etching, deposition, and ion implantation facilities within semiconductor processing. This guide is structured to assist maintenance workers through pre-, during and post-MW phases, ensuring easy comprehension and adherence to safety protocols. It highlights the necessity of safety and health measures throughout the MW process to protect personnel. The guide is enriched with real-life scenarios and visual aids, including cartoons and photographs, to aid in the understanding and implementation of safety and health principles. Conclusions: This OSH guide is designed to enhance the protection of workers engaged in maintenance activities in the electronics sector, particularly in semiconductor manufacturing. It aims to improve compliance with safety and health standards in these high-risk environments.

• Journal of Microbiology and Biotechnology
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• 제34권4호
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• pp.846-853
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• 2024

Adzuki bean (Vigna angularis), which provides plant-based proteins and functional substances, requires a long soaking time during processing, which limits its usefulness to industries and consumers. To improve this, ultrasonic treatment using high pressure and shear force was judged to be an appropriate pretreatment method. This study aimed to determine the optimal conditions of ultrasound treatment for the improved hydration of adzuki beans using the response surface methodology (RSM). Independent variables chosen to regulate the hydration process of the adzuki beans were the soaking time (2-14 h, X₁), treatment intensity (150-750 W, X₂), and treatment time (1-10 min, X₃). Dependent variables chosen to assess the differences in the beans post-immersion were moisture content, water activity, and hardness. The optimal conditions for treatment deduced through RSM were a soaking time of 12.9 h, treatment intensity of 600 W, and treatment time of 8.65 min. In this optimal condition, the values predicted for the dependent variables were a moisture content of 58.32%, water activity of 0.9979 a_w, and hardness of 14.63 N. Upon experimentation, the results obtained were a moisture content of 58.28 ± 0.56%, water activity of 0.9885 ± 0.0040 a_w, and hardness of 13.01 ± 2.82 g, confirming results similar to the predicted values. Proper ultrasound treatment caused cracks in the hilum, which greatly affects the water absorption of adzuki beans, accelerating the rate of hydration. These results are expected to help determine economically efficient processing conditions for specific purposes, in addition to solving industrial problems associated with the low hydration rate of adzuki beans.

• 한국발생생물학회지:발생과생식
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• 제28권2호
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• pp.47-54
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• 2024

In eukaryotes, RNA splicing, an essential biological process, is crucial for precise gene expression. Inaccurate RNA splicing can cause aberrant mRNA production, disrupting protein synthesis. To regulate splicing efficiency, some splicing factors are reported to undergo Ubiquitin-like Modifier (SUMO)ylation. Our data indicate that in Saccharomyces cerevisiae, the SUMO protease, Ulp2, is involved in splicing. In the ulp2Δ mutant, some ribosomal protein (RP) transcripts exhibited a significant increase in the levels of intron-containing pre-mRNA because of improper splicing. Moreover, we confirmed Ulp2 protein binding to the intronic regions of RP genes. These findings highlight a critical Ulp2 role in RP transcript splicing.