• 한국실내디자인학회논문집
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• 제13권3호
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• pp.43-51
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• 2004

1"his Study is to make research a Image and Symbol in the Gothic Architecture. Firstly, the concept of the symbol and the image effect are essentially based on the meaning that the activity of consciousness take on the constitution of the symbol. Therefore the image represent the deepest content of human nature has been imagination and reality. Secondly, the symbol concept showed in Gothic Architecture was associated with the passion of the order of middle ages. The world, the cosmos and the history had been revealed in Gothic architecture. In Gothic Image, Emile Male maintained the symbol of the Catholic Church as above mentioned. The Catholic Church was mirror of the natural, the institution, the moral and history, then this passion of the order was a christian order. Especially, E. Panofsky said that the scholastic method was shown in Gothic architecture. He assert that it was especially dialectic method used in theology. That is, he explained the transfiguration of Gothic Architecture with the process of thesis, anti-thesis, synthesis. These symbolize light, magnitude, clearness. Finally, symbolic image is important in Post-Modem architecture at present. Post-Modern architecture is associated with the public and the Pluralism. Post-Modern architecture attempt to communicate as symbolic language among the assumption for diverse aspect of culture.

• Genomics & Informatics
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• 제9권3호
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• pp.136-137
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• 2011

Methylation of cytosine is a post-synthesis modification that does not affect the primary DNA sequence but greatly influences gene expression level and phenotypes of an organism. As high-throughput sequencing of bisulfite-treated DNA is the most efficient method to identify methylated sites, several tools to map sequencing reads on a reference are available. But tools to visualize and to interpret the methylation level of methylation sites are currently insufficient. Herein, we present a novel tool to visualize the methylation level of CpG sites.

• Fibers and Polymers
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• 제3권4호
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• pp.147-152
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• 2002

Copper (II) salts are used as metallizing agents in the synthesis of new non-genotoxic direct dyes for cotton. Specifically, cotton fabric is dyed with non-genotoxic disazo direct dyes and then treated with copper salts. The complexes are characterized by neutron activation analysis, absorption spectrometry and standard Salmonella mammalian mutagenicity assay, and the after-treated fabrics are evaluated for lightfastness and washfastness. Direct dyes possessing ortho-propoxy and ortho'-hydroxy substituted systems formed the corresponding nonmutagenic 1:2 dye:metal complex and undergo significant improvement in lightfastness following metallization.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.178.2-178.2
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• 2003

Naturally occurring sugar mimics with a nitrogen in the ring are classified into five structural classes: polyhydroxylated pyrrolidines, piperidines, indolizidines. pyrrolizidine, and nortropanes. Glycosidase are involved in a wide range of important biological processes, such as intestinal digestion, post-translational processing of glycoproteins and the lysosomal catabolism of glycoconjugate. The realization that alkaloidal sugar mimics might have enormous therapeutic potential in many diseases such as viral infection, cancer and diabetes has led to increasing interest and demand for these compounds. (omitted)

• 대한치과교정학회지
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• 제50권5호
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• pp.314-323
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• 2020

Objective: To identify the available evidence on the effects of rapid maxillary expansion (RME) with three-dimensional imaging and provide meta-analytic data from studies assessing the outcomes using computed tomography. Methods: Eleven electronic databases were searched, and prospective case series were selected. Two authors screened all titles and abstracts and assessed full texts of the remaining articles. Seventeen case series were included in the quantitative synthesis. Seven outcomes were investigated: nasal cavity width, maxillary basal bone width, alveolar buccal crest width, alveolar palatal crest width, inter-molar crown width, inter-molar root apex width, and buccopalatal molar inclination. The outcomes were investigated at two-time points: post-expansion (2-6 weeks) and post-retention (4-8 months). Mean differences and 95% confidence intervals were used to summarize and combine the data. Results: All the investigated outcomes showed significant differences post-expansion (maxillary basal bone width, +2.46 mm; nasal cavity width, +1.95 mm; alveolar buccal crest width, +3.90 mm; alveolar palatal crest width, +3.09 mm; intermolar crown width, +5.69 mm; inter-molar root apex width, +2.85 mm; and dental tipping, +3.75°) and post-retention (maxillary basal bone width, +2.21 mm; nasal cavity width, +1.55 mm; alveolar buccal crest width, +3.57 mm; alveolar palatal crest width, +3.32 mm; inter-molar crown width, +5.43 mm; inter-molar root apex width, +4.75 mm; and dental tipping, 2.22°) compared to pre-expansion. Conclusions: After RME, skeletal expansion of the nasomaxillary complex was greater in most caudal structures. Maxillary basal bone showed 10% post-retention relapse. During retention period, uprighting of maxillary molars occurred.

• Restorative Dentistry and Endodontics
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• 제47권3호
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• pp.27.1-27.14
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• 2022

Objectives: This systematic review and meta-analysis aimed to assess the association of cigarette smoking with the prevalence of post-endodontic apical periodontitis in humans. Materials and Methods: We searched through PubMed/Medline, Web of Science, and Scopus from inception to December 2020. Risk of bias was performed by using the Newcastle-Ottawa Scale for cross-sectional, cohort, and case-control studies. We performed the statistical analysis in Review Manager 5.3 (RevMan 5.3). Results: 6 studies met the inclusion criteria for qualitative and quantitative synthesis. Statistical analysis of these studies suggests that there were no differences in the prevalence of post endodontic apical periodontitis (AP) when comparing non-smokers vs smoker subjects regarding patients (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.31-1.49; I2 = 58%) and teeth (OR, 1.71; 95% CI, 0.99-2.93; I2 = 72%). Conclusions: Our findings suggest that there was no association between cigarette smoking and post-endodontic apical periodontitis, as we did not find statistical differences in the prevalence of post-endodontic AP when comparing non-smokers vs smoker subjects. Therefore, smoking should not be considered a risk factor associated with endodontic failure.

• 한국동물학회지
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• 제32권4호
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• pp.404-411
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• 1989

In this study, we attempted to determine the precise patterns of protein synthesis during the second cleavage in mouse. F1 hybrid 2-cell embryos showing a highly synchronized cell cycle and outbreed ICR strain 2-cell embryos were used. The patterns of protein synthesis during the second cleavage showed the sequential changes in the F1 hybrid and ICR strain 2-cell embryos. Moreover, we examined the effects of mitotic and transcriptional inhibitors such as colcemid and a-amanitin on the protein synthesis in the late 2-cell embryos of ICR strain. Treatment of colcemid (0.1mg/ml) blocked the second cleavage, but did not affect on the change of protein synthesis. However, treatment of a-amanitin induced the synthesis of two set of polypeptides without affecting on synthesis of other proteins and cleavage. It thus seems that the appearance of a-amanitin-sensitive proteins may be not involved in the second cleavage. Therefore, these results indicate that the second cell cycle in mouse embryos appears to be regulated at post transcriptional level, presumably independent on the expression of embryonic genome. 본 연구는 생쥐 배아의 2세포기 분열과정중 단백질 합성양상과 단백질합성에 미치는 colcemid와 $\alpha$-amanitin의 영향을 조사하였다 이를 위하여 체내 수정된 ICR strain의 2세포기 배아와 매우 일치된 초기배아 분열양상을 보여주는 체외 수정된 F1 (C57BL x CBA) hybrid 2세포기 배아를 사용하였다. 두 종류의 2세포기 배아에서 단백질 합성은 분열단계에 따라서 매우 일치된 변화를 보여 주었다. 또한 유사분열 억제제인 colcemid (0.1mg/ml)의 처리는 2세포기 배아분열을 억제하였으나, 단백질 합성에는 아무런 변화를 주지 못하였다. 그리고 후기 2세포기 배아에 전사 억제제인 a-amanitin (100mg/ml)을 처리하였을 때 세포분열이나 다른 단백질의 합성에는 아무런 영향이 없이 단지 두개의 단백질의 합성만을 유도하였다. 이는 아마도 a-amanitin의 stress효과에 기인하는 것으로 추측된다. 따라서 생쥐 2세포기 배아의 분열과정은 배아게놈의 유전자 발현과는 무관하게 이미 합성되어 존재하는 mRNA에 의하여 조절되는 것으로 사료된다.

• 한국결정성장학회지
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• 제31권2호
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• pp.78-83
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• 2021

본 연구에서는 수열반응법을 이용하여 3차원 구조를 갖는 NiCo2O4 입자를 합성했다. 수열합성에서 반응조건 [Ni]/[Co] 비율, 반응시간과 열처리온도를 달리하여 입자의 조성과 형상을 조절했다. 최적의 조건을 결정하고자 XRD, SEM을 통해 입자를 분석하였으며, [Ni]/[Co] 1:2 비율, 반응시간 12시간, 열처리 400℃ 4시간 조건에서 3차원 구조를 갖는 단일상의 NiCo2O4가 합성하였다. 합성된 NiCo2O4 나노구조체의 글루코스 센서 특성평가 결과, 글루코스에 대해 높은 민감도와 탁월한 선택성을 나타냈다. 본 연구를 통해 합성한 NiCo2O4 나노구조체는 향후 비효소 기반 전기화학적 글루코스 센서로 널리 응용될 수 있을 것으로 기대된다.

• 생명과학회지
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• 제33권9호
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• pp.724-729
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• 2023

본의 연구 결과는 무기질 구리가 전사, 번역 및 번역 후의 여러 단계에서 아펠린 생합성에 억제 효과를 발휘한다는 것을 명확하게 보여준다. 그러나 바토쿠프로인디설폰산의 구리 킬레이터로 처리하면 구리의 억제 영향이 효과적으로 역전되어 포유류 골격근 세포에서 아펠린 생합성의 구리 의존적 특성이 확인되었다. 이러한 결과는 구리가 마이오카인 아펠린의 생합성 조절에 중요한 역할을 한다는 최초의 보고이며, 구리 관련한 근육감소증의 예방 및 치료의 전략 개발에 유용한 실마리를 제공할 수 있다.

• Journal of Ceramic Processing Research
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• 제21권
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• pp.47-52
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• 2020

Graphene was synthesized using rapid thermal chemical vapor deposition (RT-CVD) equipment designed to produce largearea graphene at high speed. The effects of methane (CH₄), argon (Ar), and hydrogen (H₂) gases were investigated between 800 ℃ and 1,000 ℃ during heating and cooling in the graphene synthesis process. The findings reveal that multilayer domains increased due to hydrogen pretreatment with increase in temperature. Furthermore, when pretreated with the same gas, it was confirmed that the post-argon-treated sample cooled from 1,000 ℃ to 800 ℃ had a higher I_D/I_G value than that of the other samples. This result was consistent with the sheet resistance properties of graphene. The sample prepared in methane atmosphere maintained during both the pre-treatment and post-treatment demonstrated the lowest sheet resistance of 787.49 Ω/sq. Maintaining the methane gas atmosphere in the high-temperature region during graphene synthesis by RT-CVD reduced the defects and improved the electrical property.