• Journal of Technology Innovation
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• v.28 no.4
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• pp.165-175
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• 2020

In this viewpoint paper, we overlook the potential of the data industry and the strategies needed in order to survive in this new socio-economic order brought by COVID-19. The social distancing culture is leading to the expansion and centralization of data. The government established the development plan of the data industry ecosystem and the capital flow is following this stream, so this is an opportunity for those in the data business. To survive and grow in the data industry ecosystem, we need to identify quality characteristics that have a comparative advantage over competitors based on high data quality and need to determine the target business segmentation to avoid wasting resources and make efficient investments.

• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.757-767
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• 1999

Background: Diagnosis by smear and/or cultures of the Mycobacterium tuberculosis from body fluid or biopsy specimen is "Gold standard". However the sensitivity of the direct microscopy is relatively low and culture of mycobacteria is time consuming. Despite an explosion in the techniques of rapid identification of mycobacteria by molecular genetic means, it is laborious and expensive and then rapid, inexpensive serodiagnosis is interested in diagnosis of tuberculosis. But sensitivity and specificity of known serologic antigen is not full sufficient level and then new antigen develop and combination cocktails of new developed antigens by ELISA are needed. Method: To compare the efficacy of different mycobacterial specific antigen and to assess the applicability of the combination of several different antigens in the diagnosis of tuberculosis, five ELISA tests derived 14KDa, 16KDa, 19KDa, 23KDa, 38KDa were evaluated in 57 active pulmonary patient and 24 inactive post-therapy follow up patient and 48 normal control. Results: The optical densities of ELISA test with 14KDa, 16KDa, 19KDa, 23KDa, 38KDa were significantly higher in active tuberculosis cases than in normal control(P<0.001, P<0.001, P<0.027, P<0.001, P<0.001) and those with 16KDa, 38KDa were significant higher in active tuberculosis cases than in inactive post-therapy follow up cases(P<0.01. P<0.001) and those of 14KDa, 16KDa, 23KDa, 38KDa were significant higher in inactive post-therapy follow up cases than in normal control(P<0.008. P<0.01. P<0.006. P<0.001). The sensitivity of 14KDa, 16KDa, 19KDa, 23KDa, 38KDa in active pulmonary patient cases was 42.1%, 43.9%, 15.8%, 28.0%, 70.2%, respectively and the specificity of 14KDa, 16KDa, 19KDa, 23KDa, 38KDa in active pulmonary patient cases was 95.8%, 95.8%, 91.7%, 89.6%, 93.8%, respectively. The sensitivity and specificity of combination 38KDa with 16KDa was 87% and 93.7%. Conclusion: The sensitivity and specificity of new antigens for serodiagnosis of the tuberculosis still remains limited at around 70%, which makes its a poor diagnostic tool for disease confirmation. A combination of cocktail antigens provided by cut-off value adjustment for serodiagnosis of tuberculosis some improved diagnostic yield than single antigen serologic test.

• YAKHAK HOEJI
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• v.40 no.3
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• pp.347-350
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• 1996

The post-antibiotic effect (PAE), which is defined as the period of time lag that the target organisms resume normal growth rate after complete removal of the antibiotics, of LB 20304 and ciprofloxacin was evaluated against Staphylococcus aureus 6538p and Escherichia coli 3190Y, respectively. The PAE was estimated by adding each antibiotic to a log phase of growth and incubating at $37^{\circ}$C for 1 h.Antibiotic was removed by centrifugation, and total viable cell counts were determined hourly for a further 10 h. The PAEs of LB20304 against S. aureus at concentrations of $1{\times}MIC\;and\;2{\mu}g/ml$ were 10 min and 93min, respectively. LB20304 showed a comparable PAE to ciprofloxacin. Against E. coli, the PAE of LB20304 was also similar to that of ciprofloxacin at concentration of $4{\times}MIC$ but it was much longer than that of ciprofloxacin at concentration of 2${\mu}g/ml$. LB20304 showed higher lethality than ciprofloxacin against both S. aureus and E. coli strains.

• Transactions of the Korean Society of Mechanical Engineers
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• v.19 no.9
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• pp.2283-2296
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• 1995

Experiments of normal shock wave/turbulent boundary layer interaction were conducted in a supersonic diffuser. The flow Mach number just upstream of the normal shock wave was in the range of 1.10 to 1.70 and Reynolds number based upon the turbulent boundary layer thickness was varied in the range of 2.2*10$^{[-994]}$ -4.4*10$^{[-994]}$ . The wall pressures in streamwise and spanwise directions were measured for two test cases, in which the turbulent boundary layer thickness incoming into the supersonic diffuser was changed. The results show that the interactions of normal shock wave with turbulent boundary layer in the supersonic diffuser can be divided into three patterns, i.e., transonic interaction, weak interaction and strong interaction, depending on Mach number. The weak interactions generate the post-shock expansion which its strength is strong as the Mach number increases and the strong interactions form the pseudo-shock waves. From the spanwise measurements of wall pressure, it is known that if the flow Mach number is low, the interacting flow fields essentially appear two-dimensional, but they have an apparent 3-dimensionality for the higher Mach numbers.

• Korean Journal of Bronchoesophagology
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• v.16 no.1
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• pp.16-19
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• 2010

NOTES (Natural orifice transluminal endoscopic surgery) is a new technique in minimally invasive procedure, surgeon use normal orifice and hollow viscus for procedurs as approaching route, Currently the NOTES are performed for diagnostic and therapeutic purpose by some investigators in research setting. NOTES has potential benefit in terms of sear, pain, post op recovery. Rut Bacterial contamination, deal with major complication are needed more stud) and development.

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.10b
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• pp.31-31
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• 2003

Magic technologies and smart biomarkers at the Omics Age！ This slogan is not only for the pharmaceutical companies as the speedy and cost-reduced development of global drug, but for all of the toxicologists and biologist. Biomarker refers to a variety of physiologic, pathologic, or anatomic measurements that are thought to relate to some aspect of normal or pathological processes (Temple 1995; Lesko and Atkinson 2001).(omitted)

• Child Health Nursing Research
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• v.22 no.4
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• pp.326-335
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• 2016

Purpose: It is crucial to provide adequate enteral nutrition for postoperative recovery, wound healing and normal growth in infants in pediatric cardiac ICUs. This study was done to develop a feeding protocol using the vaso-active inotropic (VAI) score and to evaluate the impact of nutritional outcomes following the new feeding protocol for infants who underwent cardiac surgery. Methods: This study consisted of three phases. First, a feeding protocol was developed based on a literature review. Second, ten experts rated the content validity. Third, a comparison study was conducted to evaluate the impact of the new feeding protocol. Data were analyzed using SPSS Version 20. Results: Twenty-nine infants were enrolled in the pre-protocol group, and 22 infants in the post-protocol group. Patients in the 2 groups were similar. Time to reach feeding goal was significantly decreased from 56.0 (27-210) hours to 28.5 (10-496) hours in the post-protocol group (Z=-4.22, p<.001). Level of enteral feeding knowledge among nurses increased significantly after implementation of the protocol. Conclusion: The feeding protocol using VAI score facilitates the achievement feeding goal to decrease feeding interruptions and help nurses in their practice. Larger studies are necessary to examine clinical outcomes following the implementation of this feeding protocol.

• Steel and Composite Structures
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• v.44 no.3
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• pp.407-421
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• 2022

Prefabricated hybrid wind turbine towers (WTTs) are promising due to height increase. This study proposes the use of ultra-high performance concrete (UHPC) to develop a new type of WTT without the need to use reinforcement. It is demonstrated that the UHPC WTT structure without reinforcing bars could achieve performance similar to that of reinforced concrete WTTs. To simplify the design of WTT, a design approach for the calculation of stresses at the horizontal joints of a WTT is proposed. The stress distribution near the region of the horizontal joint of the WTT structure under normal operating conditions and different load actions is studied using the proposed approach, which is validated by the finite element method. A further parametric study shows that the degree of prestressing and the bending moment both significantly affect the principal stress. The shear-to-torsion ratio also shows a significant influence on the principal tensile stress.

• Journal of Distribution Science
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• v.19 no.11
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• pp.5-15
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• 2021

Purpose: The current study aims at knowing and testing factors supporting business and how to distribute it for resilience business in new normal era. Factors Supporting business resilience will be seen in terms of entrepreneurial competence, technology utilization and government support for business resilience through entrepreneurial spirit as an intervening variable. Research design, data, and methodology: A constructed questionnaire in direct survey and interview was conducted with 97 respondents in South Sulawesi. Partial Least Square (PLS) analysis, was utilized to analyze and verify all the data. Results: This study indicated entrepreneurial competence and utilization of technology have a positive and significant effect on entrepreneurial spirit, while government support has no significant effect on entrepreneurial spirit. This study also indicated that entrepreneurial spirit has a significant effect on business resilience. Conclusion: To increase business resilience, it is very important to have entrepreneurial skills and mastery on utilization of technology. To anticipate future crises, entrepreneurial competencies must be evenly distributed both for business owners and for all members of the organization. To institutionalize crisis management in business, it is important for SMEs in Indonesia to develop an institutionalized Business Crisis Management.

• Journal of the Korean Society of Physical Medicine
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• v.1 no.1
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• pp.59-66
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• 2006

Purpose : The purpose of this study was to investigate the effects of diaphragmatic breathing on activation of lumbar paraspinal muscles of normal healthy people. Diaphragmatic breathing may affect activation of trunk muscles. The assumptions are as follows: the crural diaphragm attatches to the lumbar vertebrae from L1 to L3, the voluntary downward pressurization of the diaphragm increases intra-abdominal pressure, and this increases the stiffness of the spine. Methods : Sixty male college students ranging 19 to 34 years were screened and % maximal voluntary contraction(% MVC) of trunk muscles on the four positions of back extension exercise was compared during the pre and post of inspiration of diaphragmatic breathing. Results : 1. % MVC of right and left erector spinae had the statistically significant difference between pre and post inspiration of diaphragmatic breathing in the dynamic right arm and left leg extension position(p<0.05). 2. % MVC of right and left erector spinae had the statistically significant difference between pre and post inspiration of diaphragmatic breathing in the dynamic left arm and right leg extension position(p<0.05). 3. % MVC of right and left erector spinae had the statistically significant difference between pre and post inspiration of diaphragmatic breathing in the static lying prone extension position(p<0.05). 4. % MVC of right and left erector spinae had the statistically significant difference between pre and post inspiration of diaphragmatic breathing in the static lying on prone position(p<0.05). Conclusion : This study will be used as the purpose of data collection of lumbar paraspinal muscles on diaphragmatic breathing and be introduced as the new therapeutic intervention for management of patients with back pain.