• 대한한방내과학회지
• /
• 제45권2호
• /
• pp.131-139
• /
• 2024

In this case report, we describe the effects of Korean Medicine therapies, including Bunshimgi-eum, on a patient hospitalized with insomnia due to fibromyalgia in a Korean Medicine Hospital. We treated the patient with Bunshimgi-eum for 21 of 27 hospital days. Post-treatment, we used the Insomnia Severity Index (ISI) to measure the severity of insomnia. To determine the severity of multiple pain, including neck, low back, Lt. shoulder, Lt. elbow, Rt. knee, and hand, we used the Numerical Rating Scale (NRS). For evaluation of generic health status, we used the European Quality of Life-5 Dimensions (EQ-5D) scale. After the treatment, the patient's clinical symptoms improved, according to the ISI, NRS, and EQ-5D. The results of this case study suggest that Korean Medicine therapies, including Bunshimgi-eum, may have positive effects as a treatment for insomnia related to fibromyalgia.

• Smart Structures and Systems
• /
• 제33권2호
• /
• pp.119-131
• /
• 2024

Drift angle is a significant index for diagnosing post-event structures. A common way to estimate this drift response is by using modal parameters identified under natural excitations. Although the modal parameters of shear structures cannot be identified accurately in the real environment, the identification error has little impact on the estimation when measurements from several floors are used. However, the estimation accuracy falls dramatically when there is only one accelerometer. This paper describes the susceptibility of single sensor identification to modelling error and simulations that preliminarily verified this characteristic. To make a robust evaluation from measurements of one floor of shear structures based on imprecisely identified parameters, a novel scheme is devised to approximately correct the mode shapes with respect to fictitious frequencies generated with a genetic algorithm; in particular, the scheme uses constrained minimization to take both the mathematical aspect and the realistic aspect of the mode shapes into account. The algorithm was validated by using a full-scale shear building. The differences between single-sensor and multiple-sensor estimations were analyzed. It was found that, as the number of accelerometers decreases, the error rises due to insufficient data and becomes very high when there is only one sensor. Moreover, when measurements for only one floor are available, the proposed method yields more precise and appropriate mode shapes, leading to a better estimation on the drift angle of the lower floors compared with a method designed for multiple sensors. As well, it is shown that the reduction in space complexity is offset by increasing the computation complexity.

• Pediatric Infection and Vaccine
• /
• 제23권3호
• /
• pp.180-187
• /
• 2016

목적: 본 연구는 병원 내에서 의도치 않게 수두-대상포진 바이러스(varicella zoster virus [VZV]) 감염 환자에 노출된 의료진과 소아 입원 환자의 사례를 대상으로 노출 후 예방 조치와 그에 따른 2차 수두 감염 발생 여부를 분석하고자 하였다. 방법: 2010년 1월부터 2015년 12월까지 서울대학교 어린이병원에 입원한 수두 혹은 대상포진 환자중 초기에 적절한 격리 조치가 이루어지지 않았던 사례와 노출자를 대상으로 하였다. 노출자의 VZV에 대한 면역력과 면역 저하 상태의 유무에 따라 노출 후 예방 조치를 시행하였다. 의무기록을 통하여 사례 환자와 노출자들의 임상 정보 및 2차 감염 발생 여부를 조사하였다. 결과: 2010년부터 2015년까지 147명의 VZV 감염 환자가 입원하였고 이 중 의도치 않게 노출되었던 환자는 13명이었다. 이 중 5명(38.5%)의 사례 환자는 수두 백신 접종력이 확인되었다. 총 86명의 환자가 다인용 병실에서 사례 환자에 노출되었고, 62.8% (54/86)에서 VZV에 대한 면역력이 있었다. 27명의 노출 환자에게 노출 후 예방 조치를 시행하였으며, VZIG를 투약받은 환자는 23명이었고 수두 백신을 접종받은 환자는 4명이었다. 2차 수두가 발병한 환자는 4명으로, 예방 조치를 받지 않은 소아 1명과 예방 조치를 받은 27명 중 3명에서 감염이 확인되었다. 이들은 모두 한 명의 사례 환자에게 노출되었다. 2차 수두 감염률은 4.7% (4/85)이었고, 노출 후 예방 조치를 받은 환자 중 2차 감염률은 11.1% (3/27)이었다. 면역 기능이 정상인 환자에서 2차 수두 감염률은 1.9%, 면역 저하 환자에서는 9.7%이었다. 결론: 수두의 진단이 지연되면 병원에서 VZV에 노출되는 사례가 발생할 수 있으며 이로 인하여 감수성이 있는 소아나 면역 저하자에게 수두가 2차적으로 발생할 수 있다. VZV에 대한 면역력 여부를 기반으로 노출 후 예방 조치 여부를 결정하는 국내 기준의 적정성을 재고할 필요가 있다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권6호
• /
• pp.2531-2535
• /
• 2015

Background: Breast cancer diagnosed in young women may be more aggressive, with higher rates of local and distant recurrence compared to the disease in older women. Epidemiologic evidence suggests that Korean women have a lower incidence of breast cancer than women in the United States, but that they present at a younger age than their American counterparts. We sought to compare risk factors and management of young women with breast cancer in Boston, Massachusetts (US) with those in Seoul, South Korea (KR). Materials and Methods: A retrospective review was performed of consecutive patients less than 35 years old with a diagnosis of breast cancer at academic cancer centers in the US and KR from 2000-2005. Patient data were obtained by chart review. Demographic, tumor and treatment characteristics were compared utilizing Pearson's chisquare or Wilcoxon rank-sum tests where appropriate. All differences were assessed as significant at the 0.05 level. Results: 205 patients from the US and 309 from KR were analyzed. Patients in US were more likely to have hormone receptor positive breast cancer, while patients in KR had a higher rate of triple negative lesions. Patients in US had a higher mean body mass index and more often reported use of birth control pills, while those in the KR were less likely to have a sentinel node procedure performed or to receive post mastectomy radiation. Conclusions: Patients under 35 diagnosed with breast cancer in the US and KR differ with respect to demographics, tumor characteristics and management. Although rates of breast conservation and mastectomy were similar, US patients were more likely to receive post mastectomy radiation. The lower use of sentinel node biopsy is explained by the later adoption of the technique in KR. Further evaluation is necessary to evaluate recurrence rates and survival in the setting of differing disease subtypes in these patients.

• Korean Journal of Radiology
• /
• 제24권4호
• /
• pp.349-361
• /
• 2023

Objective: To quantitatively assess the pulmonary vasculature using non-contrast computed tomography (CT) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) pre- and post-treatment and correlate CT-based parameters with right heart catheterization (RHC) hemodynamic and clinical parameters. Materials and Methods: A total of 30 patients with CTEPH (mean age, 57.9 years; 53% female) who received multimodal treatment, including riociguat for ≥ 16 weeks with or without balloon pulmonary angioplasty and underwent both non-contrast CT for pulmonary vasculature analysis and RHC pre- and post-treatment were included. The radiographic analysis included subpleural perfusion parameters, including blood volume in small vessels with a cross-sectional area ≤ 5 mm² (BV5) and total blood vessel volume (TBV) in the lungs. The RHC parameters included mean pulmonary artery pressure (mPAP), pulmonary vascular resistance (PVR), and cardiac index (CI). Clinical parameters included the World Health Organization (WHO) functional class and 6-minute walking distance (6MWD). Results: The number, area, and density of the subpleural small vessels increased after treatment by 35.7% (P < 0.001), 13.3% (P = 0.028), and 39.3% (P < 0.001), respectively. The blood volume shifted from larger to smaller vessels, as indicated by an 11.3% increase in the BV5/TBV ratio (P = 0.042). The BV5/TBV ratio was negatively correlated with PVR (r = -0.26; P = 0.035) and positively correlated with CI (r = 0.33; P = 0.009). The percent change across treatment in the BV5/TBV ratio correlated with the percent change in mPAP (r = -0.56; P = 0.001), PVR (r = -0.64; P < 0.001), and CI (r = 0.28; P = 0.049). Furthermore, the BV5/TBV ratio was inversely associated with the WHO functional classes I-IV (P = 0.004) and positively associated with 6MWD (P = 0.013). Conclusion: Non-contrast CT measures could quantitatively assess changes in the pulmonary vasculature in response to treatment and were correlated with hemodynamic and clinical parameters.

• 한방재활의학과학회지
• /
• 제23권4호
• /
• pp.185-194
• /
• 2013

Objectives The aim of this study was to evaluate the efficacy and safety of micro current taping therapy (MTT) on patients with chronic low back pain (CLBP). Methods We included 50 participants who met the inclusion criteria and 5 participants dropped out during the sessions due to the following reasons: 3 participants were personal reasons, 1 participant was taking medication, 1 participant was fore arm fracture. We attached "I" shaped 40 cm, 2 tapes along the erector muscles of the spine starting from both iliac crest and another "I" shaped 30 cm, 1 tape on the painful site horizontally. This procedure was done 8 times and participants visited a total of 9 times including a final visit for evaluation. We measured visual analog scale (VAS), range of motion (ROM) and schober's test on every visit. Participants completed a questionnaire of oswestry disability index (ODI) and Beck's depression inventory (BDI) on the first and last visits. Results In VAS for pain intensity and bothersomeness, there were significant decreases after 1st, 6th treatments. In range of extension, there was significant increase after 3rd treatment at first. In range of flexion, there was significant increase after 2nd treatment at first. In range of left flexion, there was significant increase after 4th treatment at first. In range of right flexion, there was significant increase after 3rd treatment at first. in schober's test, there was significant increase after 2nd treatment at first. In VAS, ROM, schober's test, BDI, ODI, there were significant improvement after all treatments had done. Conclusions There was a significant effect of MTT on CLBP. And there was no adverse effect.

• 대한물리치료과학회지
• /
• 제10권1호
• /
• pp.47-57
• /
• 2003

The purpose of this study was to evaluate the problem on activities of daily living ; the problem which spinal cord injured patients have when they adapt in daily living ; Subjects were 113 members who used the hospital which is located in Kwangju-city from November 20, 2001 to May 20, 2002. The evaluation of the ADL was performed according to MBI and collected data were statistically analysed by SPSS PC for paired Chi-square test T-test, One way ANOVA and Duncan's post-hoc test. The result's were as follows; 1. Modified Barthel Index average mark was $63.77{\pm}33.60$ points and MBI score distribution according to characteristics of injury is as following. 1) A patient who had long duration of injury, small injury region, incomplete paralysis in paralysis degree, paraplegia in paralysis type got high MBI score as statistical and significantly(p<0.05). 2. Society adaptation state by characteristics of spinal cord injured is an following. 1) After lapse of time of disease, a patient who is injured for a long term present surrounding environmental problem, a patient who is injured for a short term shows psychological problem. In society activity, as lapse of time of disease is long, patient did many hobby activity and same private club, on the other hand as lapse of time of diseases is short, the others appeared high and significantly as statistical(p<0.01). 2) In society activity by injury region, cervical injury and thoracic injury did more hobby activity than lumbar injury and in lumbar injury same private club or religion life appeared higher than thoracic injury of cervical injury significantly as statistical(p<0.01). 3) In walk method by paralysis degree Complete paralysis had more wheelchair life than incomplete paralysis(p<0.01). 4) In serious problem by paralysis type psychological problem in quadriplegia and surrounding environmental problem in paraplegia appeared high and significantly as statistical(p<0.01). 3. In society adaptation state by MBI score difference between variables appeared but it wasn't significantly.

• 한국지반환경공학회 논문집
• /
• 제15권7호
• /
• pp.39-50
• /
• 2014

본 연구에서는 도시개발 시 저영향개발(Low Impact Development, LID) 기법을 적용하였을 때, 토양 지하수 환경과 생태경관에 미치는 영향을 총체적으로 평가하는 방법의 framework 구축을 목적으로 문헌조사 연구를 수행하였다. 그 결과 토양 지하수 환경생태 건강성은 (i) 수리지질학적 지하수 오염 취약성, (ii) 생화학적 오염도와 (iii) 토양의 오염 정화능력의 여러 요소들에 의해서 측정되어 종합 및 평가되는 것이라는 개념을 설정하였고, 이들 각각의 요소에 미치는 영향 평가를 위한 측정 항목 선정과 각 요소의 측정치를 종합화해서 등급화 및 지표화하는 방법을 제시하였다. 또한 토양 지하수 환경 건강성과 기존의 환경 영향 평가에서 고려하는 생태 및 경관 요소를 GIS(Geographic Information System)와 AHP(Analytic Hierachy Process) 기반을 활용 및 접목하여 토양 지하수뿐만 아니라 생태 경관 등 LID의 자연환경에 미치는 영향을 총체적으로 평가하는 측정 항목 및 지표 산정과 그에 따른 활용 방법을 제시하였다. LID 기술의 계획 및 설계 단계에서 활용할 수 있는 최적화를 위해서 LCIA(Life Cycle Impact Assessment) 방법상의 framework로 활용하는 것을 본 연구에서는 제안하였다.

• 대한한방내과학회지
• /
• 제45권3호
• /
• pp.519-531
• /
• 2024

Objectives: This case study reports the effectiveness of Korean medical treatment in a patient with cyclic vomiting syndrome. Methods: A 29-year-old female Korean patient with cyclic vomiting syndrome received acupuncture, electroacupuncture, herbal medicine, and moxibustion for 2 weeks in hospital. Changes in symptoms were evaluated using the Gastrointestinal Symptom Rating Scale (GSRS), Visual Analog Scale (VAS), Index for Nausea, Vomiting, and Retching (INVR), Nausea Severity Scale (NSS), Nepean Dyspepsia Index-Korean version (NDI-K), quality of life using the Functional Dyspepsia Related Quality of Life questionnaire (FD-QoL), and gastric motility using electrogastrography (EGG). Results: Post-treatment, the patient showed high satisfaction and improvement in symptoms of nausea and vomiting. The following changes were observed in scores: GSRS: 23 to 19; VAS of nausea: 88 to 95; VAS of dyspepsia: 95 to 12; INVR: 13 to 1; NSS: 17 to 5; NDI-K: 107 to 78; and FD-QoL 84 to 27. We also found positive results in Channel 3 of EGG parameters, implying the improvement of gastric motility disorder. Conclusion: Korean medical treatment can be a therapeutic option for cyclic vomiting syndrome.

• 한국안광학회지
• /
• 제18권3호
• /
• pp.347-356
• /
• 2013

목적: 비구면 다초점 인공수정체인 ReSTOR$^{(R)}$ SN6AD3 삽입안의 시력과 시기능 변화를 분석하였다. 방법: 양안 또는 단안에 비구면 다초점 인공수정체(ReSTOR$^{(R)}$ SN6AD3)를 삽입한 백내장 환자 19명의 30안을 대상으로 하였다. 수술 전, 수술 후 1주일, 1개월 및 3개월 후에 시력과 객관적인 시기능을 측정하였고 수술 3개월 후 인공수정체 삽입안의 시기능 측정값을 동일 연령대의 정상안 20명(38안)과 비교하였다. 원거리 시력은 2 m 거리에서 LCD chart ETDRS 시력표를 이용하여 측정하였고, 중간거리(50 cm)과 근거리(30 cm) 시력은 Jaeger chart를 이용하였다. 객관적인 시기능은 OQAS 장비를 이용하여 OSI (objective scatter index, 객관적 산란지수), MTF (modulation transfer function, 변조전달함수) cut off, Strehl ratio를 4 mm 동공크기에서 측정하여 수술 후 경과기간에 따른 측정값을 비교 평가하였다. 수술 3개월 째 시력 및 시기능은 객관적 평가와 주관적인 평가를 통해 동일 연령대의 정상안과 비교하였다. 결과: 나안 원거리 시력과 OSI, MTF와 Strehl ratio는 다초점 인공수정체 삽입 1개월까지 유의하게 향상되었다(p<0.05). 수술 3개월 후 다초점 인공수정체 삽입안의 MTF와 Strehl ratio는 정상 대조군의 수준으로 회복되었지만, OSI는 대조군보다 높은 값으로 측정되었다(p<0.001). 자각적인 원거리 및 근거리 시력에 대한 만족도는 높았지만, 중간거리 시력에 대한 만족도가 낮으며 눈부심과 빛 번짐 증상이 나타났다. 결론: 비구면 다초점 인공수정체 삽입안의 시기능은 수술 1개월 후부터 안정화되며 동일 연령대의 정상안의 수준으로 개선되지만 만족스러운 중간거리 시력을 제공하지 못하며 눈부심과 빛 번짐의 시각적 불편감이 나타나는 것으로 사료된다.