• Title/Summary/Keyword: Positioning Block

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Phylogenetic Positioning of a Strongyloides stercoralis Isolate Recovered from a Korean Patient and Comparison with Other Asian Isolates

  • Bae, Jaeho;Jeong, Mi Jin;Shin, Dong hoon;Kim, Hyun Woo;Ahn, Sung Ho;Choi, Jun Ho;Yu, Hak Sun
    • Parasites, Hosts and Diseases
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    • v.58 no.6
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    • pp.689-694
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    • 2020
  • Strongyloidiasis is caused by Strongyloides stercoralis and is one of the most neglected tropical diseases in tropical and subtropical regions. Although several strongyloidiasis cases have been reported in Korea, genetic analysis of Korean isolates is still incomplete. In this study, a parasite was isolated from a 61-year-old man diagnosed with strongyloidiasis during the treatment of lymphoma on his retroperitoneal lymph node. Diffuse symmetric wall thickening from the ascending to descending colon and a nematode-infected intestine was observed following microscopic examination. Genomic DNA was isolated from a patient tissue block, and S. stercoralis was identified by PCR and sequencing (18S rDNA). In order to determine phylogenetic location of a Korean isolate (named KS1), we analyzed cox1 gene (500-bp) and compared it with that from 47 previous S. stercoralis isolates (28 human isolates and 19 canid isolates) from Asian countries. Our results showed that phylogenetic tree could clearly be divided into 5 different groups according to hosts and regions. KS1 was most closely related with the Chinese isolates in terms of genetic distance.

A Factor Analysis on Resident's Satisfaction of the Efficient Rural Development Projects: Focusing on the Rural Development Projects under the Block Grants System in Buyeo (효율적인 농산어촌지역개발사업을 위한 주민만족요인분석 -부여군 포괄보조금제도하에 지역개발사업을 중심으로-)

  • Yoon, Jun Sang;Park, Eun Byong
    • Journal of Agricultural Extension & Community Development
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    • v.19 no.4
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    • pp.773-798
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    • 2012
  • The study present the findings divide into brand naming, image, positioning. The farms built trust by consumer relationship with the farm brand. The results of the study provide insights for agricultural marketers who intend to design brand stories that align with their produce. This study is a regional case study of the factor analysis which explain residents' satisfaction of the efficient rural development projects under the Block Grants System in Buyeo. This study attempted to proceed the empirical survey of 353 residents who live in one 'town(eup)' and 13 'village(meon)' in Buyeo-gun and analyzed through SPSSWIN. The results of the satisfaction analysis in the local development projects satisfied with the overall average 3.16 and then empirically verified the important factors of the 'cultural and leisure activities', 'learning environment', 'jobs and working conditions', 'transportation'. The factor analysis of 12 variables united into three factors, the first Factors are 'transportation', 'learning environment', 'social welfare', 'cultural and leisure activities', 'Information and Communication', 'Health and Medical Services'. The second factors are 'crimes and accidents', 'environmental management', 'neighbor relations and social participation', and the third factors united into 'income and consumption activities', 'job creation' which imply the economic variables, and 'residential environment' as the common category.

A Study on the Accuracy Improvement of Control Point Surveying of Photograph Using Digital Camera (디지털 카메라를 이용한 사진기준점측량의 정확도 향상에 관한 연구)

  • Kim, Kye-Dong;Park, Joung-Hyun;Lee, Young-Wook
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.27 no.2
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    • pp.203-211
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    • 2009
  • With supply of the domestic digital camera, the relative importance of the digital camera is coming to be high gradually on aerial photogrammetry, the image of digital camera is more applied in image map or digital topographic map production. But, there are cases that do not have position information or attitude information of each photograph in digital camera results. Therefore, we wish to present additional method to get more accurate photograph control point result. In this study, One is called A method, which is the case of entering positioning information of principal point from topographic map as default values that are need to extract tie point automatically using by 56 pieces of photography that are photographed by DMC to the extent to 5 courses and 35 GCP points. The other is called B-method, which is the case of entering exterior orientation parameters that are processed by block adjustment for A-method using by 4 control points in method-1 as default values. We have analyzed about results per control points arrangement for two cases using MATCH-AT that is photograph control point measurement S/W of Germany INPHO company. As a result of analysis, accuracy of B-method was better than that of A-method, and we could get more accurate results if block adjustments are executed including self calibration. Also, it is more effective in expense side that using self calibration for photograph survey in B-method because can reduce GCP numbers.

Evaluation on the Radiation Exposure of Radiation Workers in Proton Therapy (양성자 치료 시 방사선 작업 종사자에게 미치는 방사선 피폭에 대한 평가)

  • Lee, Seung-Hyun;Jang, Yo-Jong;Kim, Tae-Yoon;Jeong, Do-Hyung;Choi, Gye-Suk
    • The Journal of Korean Society for Radiation Therapy
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    • v.24 no.2
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    • pp.107-114
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    • 2012
  • Purpose: Unlike the existing linear accelerator with photon, proton therapy produces a number of second radiation due to the kinds of nuclide including neutron that is produced from the interaction with matter, and more attention must be paid on the exposure level of radiation workers for this reason. Therefore, thermoluminescence dosimeter (TLD) that is being widely used to measure radiation was utilized to analyze the exposure level of the radiation workers and propose a basic data about the radiation exposure level during the proton therapy. Materials and Methods: The subjects were radiation workers who worked at the proton therapy center of National Cancer Center and TLD Badge was used to compare the measured data of exposure level. In order to check the dispersion of exposure dose on body parts from the second radiation coming out surrounding the beam line of proton, TLD (width and length: 3 mm each) was attached to on the body spots (lateral canthi, neck, nipples, umbilicus, back, wrists) and retained them for 8 working hours, and the average data was obtained after measuring them for 80 hours. Moreover, in order to look into the dispersion of spatial exposure in the treatment room, TLD was attached on the snout, PPS (Patient Positioning System), Pendant, block closet, DIPS (Digital Image Positioning System), Console, doors and measured its exposure dose level during the working hours per day. Results: As a result of measuring exposure level of TLD Badge of radiation workers, quarterly average was 0.174 mSv, yearly average was 0.543 mSv, and after measuring the exposure level of body spots, it showed that the highest exposed body spot was neck and the lowest exposed body spot was back (the middle point of a line connecting both scapula superior angles). Investigation into the spatial exposure according to the workers' movement revealed that the exposure level was highest near the snout and as the distance becomes distant, it went lower. Conclusion: Even a small amount of exposure will eventually increase cumulative dose and exposure dose on a specific body part can bring health risks if one works in a same location for a long period. Therefore, radiation workers must thoroughly manage exposure dose and try their best to minimize it according to ALARA (As Low As Reasonably Achievable) as the International Commission on Radiological Protection (ICRP) recommends.

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A study of Establishment on Radiomap that Utilizes the Mobile device Indoor Positioning DB based on Wi-Fi (Wi-Fi 기반 모바일 디바이스 실내측위 DB를 활용한 라디오맵 구축에 관한 연구)

  • Jeong, In Hun;Kim, Chong Mun;Choi, Yun Soo;Kim, Sang Bong;Lee, Yun
    • Journal of Korean Society for Geospatial Information Science
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    • v.22 no.3
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    • pp.57-69
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    • 2014
  • As of 2013, Korean population density is 505 persons per $1km^2$ and is ranked 3rd place in the most densely populated countries exception of city-states. It shows clearly the population is concentrated in the city area. To fulfil this urban concentration population demand, the enlargement and complexation of buildings, subway and other underground spaces connection tendency has been intensified, and it is need to construct the indoor spatial information DB as well as the accurate indoor surveying DB to promote people's safety and social welfare. In this study, Sadang station and Incheon National Airport were aimed for the construction of Wi-Fi AP location DB and RadioMap DB by collecting the indoor AP raw datas by using mobile device and those collected results were ran through the process of verification, supplementation, and analyzation. To evaluate the performance of constructed DB, 10 points in Incheon Airport- 3rd flr in block A, and 9 points in Sadang station-B1 were selected and calculated the estimated points and ran evaluation experiment using survey positioning error, which is distance between real position and the estimated position. The result shows that Incheon international airport's average and standard deviation was separately 17.81m, 17.79m and Sadang station's average and standard deviation was separately 22.64m, 23.74m. In Sadang station's case, the areas near the exit has low performance of surveying position due to fewer visible AP points than other areas. As total datas were examined except those position, it was verified that the user's location was mapping close position in surveying positioning by using constructed DB. It means that constructed DB contains correct Wi-Fi AP locations and radio wave patterns in object region, so it is considered that the indoor spatial information service based on constructed DB would be available.

Analysis of Anti-Jamming Techniques for Satellite Navigation Systems (위성항법시스템을 위한 항재밍 기술 분석)

  • Kim, Ki-Yun
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.38C no.12
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    • pp.1216-1227
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    • 2013
  • GNSS(Global Navigation Satellite System) is now being widely used in both civilian and military applications where accurate positioning and timing information are required and it is considered as a representative convergence technique in IT-Military application techniques. However, GNSS has low sensitivity level of GNSS receivers and is vulnerable to jamming signal, since the signals come from the satellite located at approximately 20,000 Km above the earth. The studies for the anti-jamming techniques in military applications have been passively performed in the domestic, because the information related GNSS are dependent on the countries that have GNSS. In this paper, we show the effect of jammer ERP by analyzing the link budget of GPS J/S power as a function of distance between jammer and receiver. Also, we categorize the anti-jamming techniques based on the functional block diagram of GNSS receiver structure and analyze the recent anti-jamming GNSS products and their technologies developed in domestic and foreign countries.

Parametric Analysis of the Solar Radiation Pressure Model for Precision GPS Orbit Determination

  • Bae, Tae-Suk
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.35 no.1
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    • pp.55-62
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    • 2017
  • The SRP (Solar Radiation Pressure) model has always been an issue in the dynamic GPS (Global Positioning System) orbit determination. The widely used CODE (Center for Orbit Determination in Europe) model and its variants have nine parameters to estimate the solar radiation pressure from the Sun and to absorb the remaining forces. However, these parameters show a very high correlation with each other and, therefore, only several of them are estimated at most of the IGS (International GNSS Service) analysis centers. In this study, we attempted to numerically verify the correlation between the parameters. For this purpose, a bi-directional, multi-step numerical integrator was developed. The correlation between the SRP parameters was analyzed in terms of post-fit residuals of the orbit. The integrated orbit was fitted to the IGS final orbit as external observations. On top of the parametric analysis of the SRP parameters, we also verified the capabilities of orbit prediction at later time epochs. As a secondary criterion for orbit quality, the positional discontinuity of the daily arcs was also analyzed. The resulting post-fit RMSE (Root-Mean-Squared Error) shows a level of 4.8 mm on average and there is no significant difference between block types. Since the once-per-revolution parameters in the Y-axis are highly correlated with those in the B-axis, the periodic terms in the D- and Y-axis are constrained to zero in order to resolve the correlations. The 6-hr predicted orbit based on the previous day yields about 3 cm or less compared to the IGS final orbit for a week, and reaches up to 6 cm for 24 hours (except for one day). The mean positional discontinuity at the boundary of two 1-day arcs is on the level of 1.4 cm for all non-eclipsing satellites. The developed orbit integrator shows a high performance in statistics of RMSE and positional discontinuity, as well as the separations of the dynamic parameters. In further research, additional verification of the reference frame for the estimated orbit using SLR is necessary to confirm the consistency of the orbit frames.

Analysis of 3D GIS- Based GNSS Visibility at Urban Area (도심에서의 3차원 GIS 기반 위성항법시스템 가시성 분석)

  • Yoo, Kyung-Ho;Kang, Tae-Sam;Sung, Sang-Kyung;Lee, Eun-Sung;Jeong, Seong-Kyun;Sin, Cheon-Sig;Lee, Sang-Uk;Lee, Young-Jae
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.35 no.12
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    • pp.1095-1100
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    • 2007
  • Visibility of the satellite navigation is related to a environmental condition of a receiver. Obstacles like buildings and trees in urban areas can block signals and have effects on accuracy and reliability of positioning. This paper presents a method of creating 3D analysis model of urban canyon of Seoul using three-Dimensional digital map. Analysis techniques of visible satellites with Ray-Polygon Collision Detection and validation of algorithm through field tests are discussed. We have compared and analyzed the visibility of GPS and Galileo with respect to separate and simultaneous tracking in view of DOP (Dilution of Precision) using the 3D GIS digital map.

Structural Basis for the Antibiotic Resistance of Eukaryotic Isoleucyl-tRNA Synthetase

  • Chung, Scisung;Kim, Sulhee;Ryu, Sung Ho;Hwang, Kwang Yeon;Cho, Yunje
    • Molecules and Cells
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    • v.43 no.4
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    • pp.350-359
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    • 2020
  • Pathogenic aminoacyl-tRNA synthetases (ARSs) are attractive targets for anti-infective agents because their catalytic active sites are different from those of human ARSs. Mupirocin is a topical antibiotic that specifically inhibits bacterial isoleucyl-tRNA synthetase (IleRS), resulting in a block to protein synthesis. Previous studies on Thermus thermophilus IleRS indicated that mupirocin-resistance of eukaryotic IleRS is primarily due to differences in two amino acids, His581 and Leu583, in the active site. However, without a eukaryotic IleRS structure, the structural basis for mupirocin-resistance of eukaryotic IleRS remains elusive. Herein, we determined the crystal structure of Candida albicans IleRS complexed with Ile-AMP at 2.9 A resolution. The largest difference between eukaryotic and prokaryotic IleRS enzymes is closure of the active site pocket by Phe55 in the HIGH loop; Arg410 in the CP core loop; and the second Lys in the KMSKR loop. The Ile-AMP product is lodged in a closed active site, which may restrict its release and thereby enhance catalytic efficiency. The compact active site also prevents the optimal positioning of the 9-hydroxynonanoic acid of mupirocin and plays a critical role in resistance of eukaryotic IleRS to anti-infective agents.

Semi-automatic Camera Calibration Using Quaternions (쿼터니언을 이용한 반자동 카메라 캘리브레이션)

  • Kim, Eui Myoung
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.36 no.2
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    • pp.43-50
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    • 2018
  • The camera is a key element in image-based three-dimensional positioning, and camera calibration, which properly determines the internal characteristics of such a camera, is a necessary process that must be preceded in order to determine the three-dimensional coordinates of the object. In this study, a new methodology was proposed to determine interior orientation parameters of a camera semi-automatically without being influenced by size and shape of checkerboard for camera calibration. The proposed method consists of exterior orientation parameters estimation using quaternion, recognition of calibration target, and interior orientation parameter determination through bundle block adjustment. After determining the interior orientation parameters using the chessboard calibration target, the three-dimensional position of the small 3D model was determined. In addition, the horizontal and vertical position errors were about ${\pm}0.006m$ and ${\pm}0.007m$, respectively, through the accuracy evaluation using the checkpoints.