• 한국안전학회지
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• 제33권4호
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• pp.111-118
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• 2018

Korea is facing a surge in the aging population, showing that population aged 65 and above will be accounted for 42.5% of the total population in 2065 with the emphasis on the over-80 population consisting of 19.2%. In response to this abrupt change in population structure, the number of traffic fatality accident referring to older driver as aged 65+ years had been increasing from 605 fatalities in 2011 to 815 fatalities in 2015 resulting in increases in 34.7% in oppose to happening to decreases in 17.2% about non-older driver. With Logit analysis based on Newton-Raphson algorithm utilizing older driver's traffic fatality data for the 2011-2015 years, it was found that the likelihood of an accident resulting in a fatality for super older driver aged 80 years and above considerably increased compared to other older driver with aging classification: 2.24 times for violation of traffic lane, 2.04 times for violation of U-turn, 1.48 times for violation of safety distance, 1.35 times for violation of obstacle of passing; also average annual increase of traffic accident cost related to super older driver was fairly increased rather than other older driver groups. Hence, this study proposes that improving and amending transport safety system and Road Traffic Act for super older driver needs to be urgently in action about license management, safe driving education, etc. when considering the increase of over-80 population in the near future. Also, implementing a social agreement with all ages and social groups to apply with advanced driver assistance system for older driver groups will be able to become a critical factor to enhance safe driving over the face of the country.

• Biomolecules & Therapeutics
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• 제16권1호
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• pp.1-8
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• 2008

Mitochondria are important sensor of apoptosis. $H_2O_2-induced$ cell death rate was enhanced by serum deprivation. In this study, we investigated whether serum deprivation using 0.5 or 3 % FBS induces apoptotic cell death through mitochondrial enzyme activation as compared to 10 % FBS. Apoptotic cell death was observed by chromosome condensation and the increase of sub-G0/G1 population. Serum deprivation reduced cell growth rate, which was confirmed by the decrease of S-phase population in cell cycle. Serum deprivation significantly increased caspase-9 activity and cytochrome c release from mitochondria into cytosol. Serum deprivation-induced mitochondrial changes were also indicated by the increase of ROS production and the activation of mitochondrial enzyme, succinate dehydrogenase. Mitochondrial enzyme activity increased by serum deprivation was reduced by the treatment with rotenone, mitochondrial electron transport inhibitor. In conclusion, serum deprivation induced mitochondrial apoptotic cell death through the elevation of mitochondrial changes such as ROS production, cytochrome c release and caspase-9 activation. It suggests that drug sensitivity could be enhanced by the increase of mitochondrial enzyme activity in serum-deprived condition.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제15권1호
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• pp.5-12
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• 2009

According to the rapid increase of the elderly population, especially frail older population, many kinds of elderly care facilities have been supplied within a relatively short period. Among them, elderly hospitals and elderly welfare facilities have occupied a major portion. The elderly hospital, which had emerged from 1994, has recorded sharp increase in facility numbers and bed numbers by the support of Korean government together with the increase of care demand. However, the concept and fundamental planning criteria of elderly hospitals have not yet been set up. This paper has derived the concept of the elderly hospital from the Medical Law and Elderly Welfare Law, and prospected the supply of it from domestic and international statistics. Also this paper has explored the fundamental design issues of elderly hospitals by analysing precedent studies and designs, and by surveying some facilities.

• 한국인구학
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• 제30권3호
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• pp.137-156
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• 2007

합계출산율이 2005년 1.08이라는 최저치에서 2006년 1.13으로 증가하면서, 이 증가가 각종 정책의 결과이기 때문에 출산력 증가가 지속될 것이라는 주장과 일시적일 것이라는 주장 간 논란이 있다. 이 연구는 인구동태신고 자료를 활용하여 최근의 출산력 변화를 집중적으로 살펴봄으로써 정책 시사점을 찾고자 하였다. 이를 위하여 출산순위별 템포조정합계출산율, 모의 연령 및 출산순위별 출산율, 연령별 유배우 출산율, 연령별 유배우 이혼율 등을 분석하였다. 전년대비 2006년 합계출산율과 출생아수가 증가한 것은 여성의 초혼과 첫째아 출산의 연기가 주춤해지면서 주로 30대 초반의 첫째아 출산 증가에 기인한다. 2006년과 2007년에는 20대 후반 여성인구의 증가(제3차 베이비붐 효과) 및 초혼의 급증으로 2007년과 2008년에는 출생아수가 증가할 것이다. 다만, 20대의 미혼율은 증가하구 유배우 출산율은 감소 추세이어서 장기적 관점의 출생아수 및 출산율 증가는 미지수이다. 또한, 첫째아와 둘째아의 출산율은 급속도로 저하되는데 반해, 셋째아 이상은 변화가 없으며, 둘째아 출산이 출산연령조정의 영향을 많이 받는 것으로 나타났다. 이는 셋째아 이상을 출산하도록 장려하는 것보다는 첫째아, 둘째아를 낳을 수 있는 사회적 환경 조성이 더 필요하고 현실적임을 시사한다. 아울러, 사회적 양육대책 마련, 고령출산에 따른 모자보건문제, 다문화가정지원책 필요성 등을 언급하고 있다.

• 한국인구학
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• 제17권1호
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• pp.1-16
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• 1994

Since 1962, the population growth control has been one of the most important aims in the 5-Year So-cioeconomic Development Plans of Korea. The annual population growth rate has dropped to tess than 1 percent in 1990 from about 3 percents in 1960s, and projected to reach to $\ulcorner$0$\urcorner$ percent in 2021. From 2021, Korean population will decrease and the age structure will be distorted because birth rate will drop suddenly and continuously. Thus, we can consider $\ulcorner$0$\urcorner$ growth population for minimizing the prob- lems on the decreasing population. To discuss the problems caused from the changes of population size and age- sex composition, we projected three kinds of population including two kinds of $\ulcorner$0$\urcorner$ growth population under different as- sumptions. The first is the population which extended the projection of National Statistical Office up to 2090. Because the TFR is assumed and fixed as low as 1.63 after 1990, the population growth rate will be under $\ulcorner$0$\urcorner$ in 2021 and drop by about 1 percent every year from around 2050. This population trend results to old age population : 38.1 of old- age dependency ratio and 46.5 years of median age. The second is the population which the size in 2021 projected by the NOS continues after 2021. To change over from the decreasing population after 2021 to the $\ulcorner$0$\urcorner$ growth one, the TFR should be in-creased up to over 3.0 in 2040-2050, which fertility level would be too high to be accepted. The third is the population which approaches to the $\ulcorner$0$\urcorner$ growth population under the assumptions that the TFR increases from 1.63 to 2.1 in the period of 2010-2030 and then the same level continues. Although the maximum population size reaches 51, 503 thousand persons, the population will approach to the stationary population with about 42.4 million persons around 2090. In this projected population there is no more serious problems on population composition, on the rapid decrease of population, and on the increase TFR level. When the $\ulcorner$0$\urcorner$ growth population continues the problems of over population caused by the populationincrease wou]d be minimized, and the problems of unusual age composition resulted from the popula-tion decrease would not be found any more. Furthermore, when the changes of population size and composition is continuing slowly, the factors of population would effect moderately to socioeconomic development and help social changes. Therefore, with the attention of the present population changes, we should adapt new and detailde population policy which is able to get the $\ulcorner$0$\urcorner$ growth population.

• Journal of Preventive Medicine and Public Health
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• 제27권1호
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• pp.135-144
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• 1994

The purpose of this study compares determinants of eldery medical cost inflation with those of other age groups by analysing aggregated data with a deterministic model. The deterministic model of per capita medical cost inflation consists of increases in price, intensity of services, and medical utilization. We used a time series data($1985{\sim}1991$) from National Medical Insurance and analyzed by age groups. In total population, the average increase rates of inpatient and outpatient medical costs were respectively 9.5% and 8.8% during 6 years and the major cause of inflation was the increase in service intensity in both of inpatient and outpatient cases. But in the population of 65 years old and over, the average increase rates of inpatient and outpatient medical costs were respectively 13.8% and 14.8% and the major cause of inflation was the increase in per-capita medical utilization in both of inpatient and outpatient cases. Also, the increase in service intensity of 65 years old and over was the highest of other age groups. This pattern was similar during study periods. We concluded that the level of medical cost-inflation and the determinants in eldery was the highest-especially in per capita medical utilization, therfore, the inflation of medical costs in eldery will be higher than other age groups for the furture in Korea.

• 대한안전경영과학회지
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• 제26권2호
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• pp.55-64
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• 2024

As the distribution of vehicles and logistics increases due to the development of human civilization and the increase in population, various roads play an important role in domestic traffic and transportation. However, the recent emergence of large cities and new cities is causing traffic problems, and the increase in roads is inevitable for the smooth distribution of vehicles and logistics. In Korea, mountainous regions occupy 70% of the country, so tunnels are used to open roads. Without this, it is difficult to open the road. Currently, there are 3,720tunnels (as of December 31, 2023) installed on high-speed national highways, general national highways, and local roads nationwide, with a length of 2.499 and increasing every year. Accordingly, fire accidents in tunnels will also increase, and due to the nature of tunnel fire accidents, there is a high probability that they will escalate into large-scale disasters, resulting in casualties and property damage, as well as significant social losses due to the disruption of logistics transportation, etc. As the possibility of potential hazards is increasing, the purpose of this study is to build a safe and efficient tunnel system by optimizing maintenance and management for fire and disaster accidents in tunnels.

• Asian-Australasian Journal of Animal Sciences
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• 제21권3호
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• pp.320-324
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• 2008

We investigated the effect of ESR gene-based selection on an improvement of litter size in the herds in real (non-experimental) conditions. The pigs were selected for three years. In the tested population the pigs were mated according to a breeding scheme where the individuals with at least one ESR-B allele were preferred in the selection. In the control group (CP; n = 140) the pigs were mated just according to a breeding scheme without knowledge of the ESR genotype. We observed a significant increase in litter size (total number of born, number of born alive and number of weaned piglets per litter) in the final tested ESR-selected population (LP; n = 184) and an insignificant increase in CP as compared with the original population (OP; n = 155). After the selection we could observe a significant increase in the frequency of allele B in LP. Frequency of the genotypes AB and BB increased in both LP and CP; the distribution of the genotypes changed significantly only in LP. An association analysis of the ESR gene effects on reproductive traits in LP showed no significant differences between the genotypes. The results of our study suggest that ESR gene-based selection can be successful also in small herds, under real (non-experimental) conditions with a respect for general breeding principles and limitations and during a short period. An examination of a larger sample population as well as an analysis of selection consequences on other traits (meat and carcass quality) could bring a more conclusive evaluation of ESR-based selection. Nevertheless, the results are encouraging especially for small breeding farms taking a perspective of better litter size improvement.

• 한국토양비료학회지
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• 제47권4호
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• pp.254-261
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• 2014

The scientific information between microbial activities and chemical properties of reclaimed tidal soil is not enough to apply for reclamation projects. This study was conducted to investigate the relation between chemical properties and microbial activities of reclaimed tidal lands located at western coastal area (25 samples from Nampo, Ewon, Sukmoon and Shihwa sites). Most of the reclaimed soils showed chemical characteristics as salinity soil except Nampo site. The major component influenced the salinity of reclaimed soil was identified as a sodium from the relationship between EC and exchangeable cation. With an increase in EC of soil, the population of mesophilic bacteria decreases whereas halotolerant and halophilic bacteria increases. The population of mesophilic bacteria increased with an increase in both organic matter and dehydrogenase activity. However, the population of halotolerant and halophilic bacteria decreased with an increase in organic matter. Based on the relation between chemical property and microbial activity of reclaimed tidal soil, electrical conductivity and organic matter as chemical properties of soil, population of mesophilic bacteria, halotolerant and halophilic bacteria and dehydrogenase activity as microbial activities could be the major parameters for reclamation process.

• 보건행정학회지
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• 제28권4호
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• pp.378-391
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• 2018

Background: People who were born in different years, that is, different birth cohorts, grow in varying socio-historical and dynamic contexts, which result in differences in social dispositions and physical abilities. Methods: This study used age-period-cohort analysis method to establish explanatory models on healthcare expenditure in Korea reflecting birth cohort factor using intrinsic estimator. Based on these models, we tried to investigate the effects of ageing population on future healthcare expenditure through simulation by scenarios. Results: Coefficient of cohort effect was not as high as that of age effect, but greater than that of period effect. The cohort effect can be interpreted to show 'healthy ageing' phenomenon. Healthy ageing effect shows annual average decrease of -1.74% to 1.57% in healthcare expenditure. Controlling age, period, and birth cohort effects, pure demographic effect of population ageing due to increase in life expectancy shows annual average increase of 1.61%-1.80% in healthcare expenditure. Conclusion: First, since the influence of population factor itself on healthcare expenditure increase is not as big as expected. Second, 'healthy ageing effect' suggests that there is a need of paradigm shift to prevention centered-healthcare services. Third, forecasting of health expenditure needs to reflect social change factors by considering birth cohort effect.