• Title/Summary/Keyword: Population increase

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Self-Consistent Calculation of Electronic Subband Structure at GaInAs/InP Heterojunction (Self-Consistent 방법에 의한 GaInAs/InP 이종접합에서의 전자 부밴드 구조계산)

  • Kong, Joon-Jin;Park, Seong-Ho;Kim, Choon-Won;Han, Baik-Hyung;,
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.26 no.1
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    • pp.38-47
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    • 1989
  • Calculated results for subband structures of electrons in GaInAs/InP hegerojunctions are presented, and their sensitivity to two parameters background impurity concentrations in the GaInAs, heterojunction barrier height-is examined. Energy levels, Fermi level and population of the ground energy level are increased with background impurity concentrations. The difference of the ground and first-excited energy levels is also increased with the increase of barrier height. However, the difference of the energy levels is almost invariable with barier height. But, population of the ground energy level decreases, but that of the first-excited energy level shows a slight increase.

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Trends in the Incidence of 15 Common Cancers in Hong Kong, 1983-2008

  • Xie, Wen-Chuan;Chan, Man-Him;Mak, Kei-Choi;Chan, Wai-Tin;He, Miao
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3911-3916
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    • 2012
  • Background: The objective of this study WAS to describe cancer incidence rates and trends among THE Hong Kong population for the period 1983-2008. Methods: Incident cases and population data from 1983 to 2008 were obtained from the Hong Kong Cancer Registry and the Census and Statistics Department, respectively. Agestandardized incidence rates (ASIR) were estimated and joinpoint regression was applied to detect significant changes in cancer morbidity. Results: For all cancers combined, the ASIR showed declining trends (1.37% in men, 0.94% in women), this also being the case for cancers of lung, liver, nasopharynx, stomach, bladder, oesophagus for both genders and cervix cancer for women. With cancer of thyroid, prostate, male colorectal, corpus uteri, ovary and female breast cancer an increase was evident throughout the period. The incidence for leukemia showed a stable trend since early 1990s, following an earlier decrease. Conclusion: Although overall cancer incidence rates and certain cancers showed declining trends, incidence trends for colorectal, thyroid and sex-related cancers continue to rise. These trends in cancer morbidity can be used as an important resource to plan and develop effective programs aimed at the control and prevention of the spread of cancer amongst the Hong Kong population. It is particularly useful in allowing projection of future burdens on the society with the increase in certain cancer incidences.

MDM2 and TP53 Polymorphisms as Predictive Markers for Head and Neck Cancer in Northeast Indian Population: Effect of Gene-Gene and Gene-Environment Interactions

  • Bhowmik, Aditi;Das, Sambuddha;Bhattacharjee, Abhinandan;Choudhury, Biswadeep;Naiding, Momota;Deka, Sujata;Ghosh, Sankar Kumar;Choudhury, Yashmin
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5767-5772
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    • 2015
  • Background: Polymorphisms in the MDM2 309 (T>G) and TP53 72 (G>C) genes are reported to increase the susceptibility to head and neck cancer (HNC) in various populations. The risk for HNC is also strongly associated with etiologic habits such as smoking, alcohol consumption and/or chewing of betel quid (BQ). In a case-control study, we investigated the significance of the above polymorphisms alone, and upon interaction with one another as well as with various etiologic habits in determining HNC risk in a Northeast Indian population. Materials and Methods: Genotyping at 309 MDM2 and 72 TP53 in 122 HNC patients and 86 cancer free healthy controls was performed by PCR using allele specific primers, and the results were confirmed by DNA sequencing. Results: Individuals with the GG mutant allele of MDM2 showed a higher risk for HNC in comparison to those with the TT wild type allele (OR=1.9, 95%CI: 1.1-3.3) (p=0.022). The risk was further increased in females by ~4-fold (OR=4.6, 95% CI: 1.1-19.4) (P=0.04). TP53 polymorphism did not contribute to HNC risk alone; however, interaction between the TP53 GC and MDM2 GG genotypes resulted in significant risk (OR=4.9, 95% CI: 0.2-105.1) (p=0.04). Smokers, BQ- chewers and alcohol consumers showed statistically significant and dose-dependent increase in HNC risk, irrespective of the MDM2 genotype. Conclusions: MDM2 genotype could serve as an important predictive biomarker for HNC risk in the population of Northeast India.

Maximizing the Selection Response by Optimal Quantitative Trait Loci Selection and Control of Inbreeding in a Population with Different Lifetimes between Sires and Dams

  • Tang, G.Q.;Li, X.W.;Zhu, L.;Shuai, S.R.;Bai, L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.21 no.11
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    • pp.1559-1571
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    • 2008
  • A rule was developed to constrain the annual rate of inbreeding to a predefined value in a population with different lifetimes between sires and dams, and to maximize the selection response over generations. This rule considers that the animals in a population should be divided into sex-age classes based on the theory of gene flow, and restricts the increase of average inbreeding coefficient for new offspring by limiting the increase of the mean additive genetic relationship for parents selected. The optimization problem of this rule was formulated as a quadratic programming problem. Inputs for the rule were the BLUP estimated breeding values, the additive genetic relationship matrix of all animals, and the long-term contributions of sex-age classes. Outputs were optimal number and contributions of selected animals. In addition, this rule was combined with the optimization of emphasis given to QTL, and further increased the genetic gain over the planning horizon. Stochastic simulations of closed nucleus schemes for pigs were used to investigate the potential advantages obtained from this rule by combining the standard QTL selection, optimal QTL selection and conventional BLUP selection. Results showed that the predefined rates of inbreeding were actually achieved by this rule in three selection strategies. The rule obtained up to 9.23% extra genetic gain over truncation selection at the same rates of inbreeding. The combination of the extended rule and the optimization of emphasis given to QTL allowed substantial increases in selection response at a fixed annual rate of inbreeding, and solved substantially the conflict between short-term and long-term selection response in QTL-assisted selection schemes.

Increased Lymphocyte Infiltration in Rheumatoid Arthritis Is Correlated with an Increase in LTi-like Cells in Synovial Fluid

  • Koo, Jihye;Kim, Soochan;Jung, Woong Jae;Lee, Ye Eun;Song, Gwan Gyu;Kim, Kyung-Su;Kim, Mi-Yeon
    • IMMUNE NETWORK
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    • v.13 no.6
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    • pp.240-248
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    • 2013
  • In this study, we compared the immune cell populations in rheumatoid arthritis (RA) synovial fluid, which shows lymphoid tissue-like structure, with those in tonsils, which are normal secondary lymphoid tissues. Firstly, we found that $CD4^-CD11b^+$ macrophages were the major population in RA synovial fluid and that B cells were the major population in tonsils. In addition, synovial fluid from patients with osteoarthritis, which is a degenerative joint disease, contained $CD4^+CD11b^+$monocytes as the major immune cell population. Secondly, we categorized three groups based on the proportion of macrophages found in RA synovial fluid: (1) the macrophage-high group, which contained more than 80% macrophages; (2) the macrophage-intermediate group, which contained between 40% and 80% macrophages; and (3) the macrophage-low group, which contained less than 40% macrophages. In the macrophage-low group, more lymphoid tissue inducer (LTi)-like cells were detected, and the expression of OX40L and TRANCE in these cells was higher than that in the other groups. In addition, in this group, the suppressive function of regulatory T cells was downregulated. Finally, CXCL13 expression was higher in RA synovial fluid than in tonsils, but CCL21 expression was comparable in synovial fluid from all groups and in tonsils. These data demonstrate that increased lymphocyte infiltration in RA synovial fluid is correlated with an increase in LTi-like cells and the elevation of the chemokine expression.

Market Evaluation of Seawater Desalination Plant considering International Water Scarcity and Expense Outlook by Use and Nation (해외 물 기근 현황과 용도별.국가별 자본지출 전망을 고려한 해수담수화 플랜트 시장성 평가)

  • Yang, Jeong-Seok;Sohn, Jinsik;Kang, Dae-Su
    • Journal of Korean Society on Water Environment
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    • v.27 no.2
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    • pp.178-187
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    • 2011
  • National water supply, water resources available, the ratio of water supply to total water resources, and the ratio of water supply to available water resources were investigated to find global seawater desalination plant market for 163 nations. Water resources available per capita from 2007 to 2016, population in water scarcity region from 2011 to 2016, and the ratio of water scarcity population to total population were also analyzed for the countries. Annual percentage increase in total municipal drinking water capital expenditure and Annual percentage increase in total industrial water market were analyzed to predict the amount of water supply by use. 76 countries are suffering from water scarcity and 60 countries among the countries have coastal regions. Forty countries were selected by considering the considerable amount and highly increasing trend of water demand by use. Most countries show increasing trend of industrial water and 82 countries have more than 4% annual increasing rate for domestic water expense from 2008 to 2016 among 163 countries. Among the 76 water scarcity countries 16 countries were finally selected by considering expense prediction by use. Middle-east, east asia, pacific ocean, and west europe regions include most selected countries.

Interactions between Entodinium caudatum and an amino acid-fermenting bacterial consortium: fermentation characteristics and protozoal population in vitro

  • Tansol Park;Zhongtang Yu
    • Journal of Animal Science and Technology
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    • v.65 no.2
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    • pp.387-400
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    • 2023
  • Ruminal protozoa, especially entodiniomorphs, engulf other members of the rumen microbiome in large numbers; and they release oligopeptides and amino acids, which can be fermented to ammonia and volatile fatty acids (VFAs) by amino acid-fermenting bacteria (AAFB). Studies using defaunated (protozoa-free) sheep have demonstrated that ruminal protozoa considerably increase intraruminal nitrogen recycling but decrease nitrogen utilization efficiency in ruminants. However, direct interactions between ruminal protozoa and AAFB have not been demonstrated because of their inability to establish axenic cultures of any ruminal protozoan. Thus, this study was performed to evaluate the interaction between Entodinium caudatum, which is the most predominant rumen ciliate species, and an AAFB consortium in terms of feed degradation and ammonia production along with the microbial population shift of select bacterial species (Prevotella ruminicola, Clostridium aminophilum, and Peptostreptococcus anaerobius). From an Ent. caudatum culture that had been maintained by daily feeding and transfers every 3 or 4 days, the bacteria and methanogens loosely associated with Ent. caudatum cells were removed by filtration and washing. An AAFB consortium was established by repeated transfers and enrichment with casamino acids as the sole substrate. The cultures of Ent. caudatum alone (Ec) and AAFB alone (AAFB) and the co-culture of Ent. caudatum and AAFB (Ec + AAFB) were set up in three replicates and incubated at 39℃ for 72 h. The digestibility of dry matter (DM) and fiber (NDF), VFA profiles, ammonia concentrations, pH, and microscopic counts of Ent. caudatum were compared among the three cultures. The co-culture of AAFB and Ent. caudatum enhanced DM degradation, VFA production, and Ent. caudatum cell counts; conversely, it decreased acetate: propionate ratio although the total bacterial abundance was similar between Ec and the Ec + AAFB co-culture after 24 h incubation. The ammonia production and relative abundance of C. aminophilum and P. anaerobius did not differ between AAFB alone and the Ec + AAFB co-culture. Our results indicate that Ent. caudatum and AAFB could have a mutualistic interaction that benefited each other, but their interactions were complex and might not increase ammoniagenesis. Further research should examine how such interactions affect the population dynamics of AAFB.

A Study on Sustainable Greenspace based on Urban Remodeling Design of an Old Apartment Building

  • Myung Sik Lee;Seung Ryeol Min
    • International Journal of High-Rise Buildings
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    • v.12 no.2
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    • pp.179-193
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    • 2023
  • It is undeniable that urban greenspace is the soul of a city. Conventional urban greenspace such as parks, community gardens, playgrounds etc. located within a city reduce the negative effects of pollution, play a major role in the survival of the urban ecosystem, and promote healthy lifestyles. Today, 55% of the world's population lives in urban areas, which is expected to increase to 68% by 2050. Projections show that urbanization and the gradual migration to urban areas combined with the fast growth of the world's population, could add another 2.5 billion people to urban areas by 2050 and almost 90% of this increase will take place in Asia(UN, 2018). As a result, many plots in the cities are and will continue to be occupied with buildings to provide residential support to the increased population. This will dangerously decrease urban greenspaces. Moreover, worldwide, food crisis, energy crisis, and social crisis is posing a great threat to the existence of mankind. Additionally, the COVID - 19 has introduced a new lifestyle where from work culture to community configuration has drastically transformed. In this scenario, residential buildings will have to serve more than just providing privacy and shelter. As urban greenspaces are being occupied by concrete residential buildings, these buildings will have to compensate for the percentage of urban green they are destroying and the issues they are imposing in the process. The goal of this thesis is to design, architecturally define and, categorize comprehensive 'sustainable Greenspace'(S.G.S) for the multi-family housing scenario. These will be different than the conventional green (veranda, rooftop green) we commonly see in residential buildings. An old, dilapidated apartment building will be the target of remodeling to fulfill the purpose of this thesis.

Modeling and Trends of Road Transport Development in Eastern European Countries

  • Viktoriia Harkava;Olena Pylypenko;Oleksandr Haisha;Armen Aramyan;Volodymyr Kairov
    • International Journal of Computer Science & Network Security
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    • v.24 no.3
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    • pp.189-195
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    • 2024
  • Road transport occupies the largest share in domestic and international transport. It is of key importance for the development of the economy, forasmuch as it provides the livelihood of the population, the development of the national economy, the possibility of establishing foreign economic relations. The purpose of the research is as follows: analysis of the current state of functioning of the road transport sector in Eastern Europe and identification of key problems and trends in its development. Research methods: Methods of grouping, comparison and generalization, correlation analisys have been used to identify the dynamics of the main indicators of road transport in Eastern Europe. The method of correlation-regression analysis has been applied to determine the impact of increasing the length of roads on the turnover of the road freight transport and the number of employed population in this area. Results. It has been found that the increase in the employed population by 96% and increase in revenues from transportation and storage of goods, postal and courier services (turnover of the road freight transport - in the original language) in the field of road transport by 82% is explained by the change in transport infrastructure capacity by increasing length of highways. According to the correlation analysis, it has been revealed that there is a high direct dependence between the length of roads and increased revenues from transportation and storage of goods in the field of road transport, as well as between the length of roads and increasing employment in this area.

Analysis of Relationship between the Spatial Characteristics of the Elderly Population Distribution and Heat Wave based on GIS - focused on Changwon City - (GIS 기반 노인인구 분포지역의 공간적 특성과 폭염의 관계 분석 - 창원시를 대상으로 -)

  • SONG, Bong-Geun;PARK, Kyung-Hun;KIM, Gyeong-Ah;KIM, Seoung-Hyeon;Park, Geon-Ung;MUN, Han-Sol
    • Journal of the Korean Association of Geographic Information Studies
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    • v.23 no.3
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    • pp.68-84
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    • 2020
  • This study analyzed the relationship between spatial characteristics and heat waves in the distribution area of the elderly population in Changwon, Gyeongsangnam-do. For analysis, the Statistics Census data, the Ministry of Environment land cover, Landsat 8 surface temperature, and the Meteorological Agency's heat wave days data were used. The spatial characteristics of the distribution of the elderly population was classified into 5 types through K-mean cluster analysis considering the land use types. The characteristics of the elderly population by spatial type were higher in the urbanized type(cluster-3), but the proportion of the elderly population was higher in the agricultural and forest area types(cluster-1, cluster-2). In the characteristics of the surface temperature and the heat wave days, the surface temperature was the highest in the urban area, but heat wave days were the highest in the rural area. As a result of analyzing the heat wave characteristics according to the spatial type of the distribution area of elderly population, cluster-2 with the largest area in agricultural areas was highest at 15.95 days, and cluster-3 with a large area in urbanized types was the lowest at 9.41 days and 9.18 days. In other words, the elderly population living in rural areas is more exposed to heat waves than the elderly population living in urban areas, and the damage is expected to increase. The results of this study could be used as basic data to prepare various policy measures for effective management and prevention of vulnerable areas in summer.