• Childhood Kidney Diseases
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• 제15권1호
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• pp.14-21
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• 2011

좌심실 비대는 심부전, 허혈성 심질환, 부정맥과 같은 심혈관계 질환의 이환율 및 사망률을 높이는 강력한 위험 인자이며 고혈압으로 초래되는 가장 초기 단계의 심장 변화 이기도 하다. 소아청소년 고혈압 환자들은 분명한 심혈관계 합병증 보다는 무증상의 좌심실 비대만 볼 수 있는 경우가 대부분이나 치료하지 않는 경우 성인에서의 심혈관 합병증으로 이행될 위험이 크다. 표적장기 손상의 가장 대표적인 증거이기도 한 좌심실 비대는 소아청소년에서 고혈압 전 단계 상태에서도 나타나므로 고혈압의 진단 당시와 추후의 추적 진료 중 정기적으로 심초음파를 통한 좌심실 질량의 측정이 이루어 져야 한다. 좌심실 비대가 보인다면 적극적인 약물 치료가 또한 이루어져야 한다.

• 근관절건강학회지
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• 제23권3호
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• pp.152-158
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• 2016

Purpose:The purpose of this study was to examine the degree of joint pain, limitation of daily activities, and frequency of outpatient visits. Methods: This secondary analysis study used the data from the fifth Korean National Health and Nutrition Examination Survey (KNHNES). The data about general characteristics, prevalence and treatment of osteoarthritis, limitation of activities of daily living (ADL) and frequency of outpatient visits and hospitalization in 424 osteoarthritis patients over 50 years old were derived from the database. Data were analyzed with complex samples in SPSS ver. 20.0. Results: Among people with knee joint pain, 79.3% reported they had more than 4 out of 10 points of the degree of pain. Meanwhile, 97.3% of people with hip joint pain reported that they had more than 4 out of 10 points of the degree of pain. People reporting 10 out of 10 point of pain were 21.4% of those with knee joint pain and 25% of those with hip joint pain. The mean of the degree of knee joint pain was 6.35, and the mean of the degree of hip joint pain was 6.89 out of 10 points. About 50% of people with osteoarthritis visited an outpatient clinic within the last 2 weeks, and 27% had limitation of ADL. Conclusion: It is necessary to develop an integrated intervention program to improve quality of life in patients with osteoarthritis.

• 여성건강간호학회지
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• 제12권4호
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• pp.355-362
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• 2006

Purpose: This study was to investigate the degree of postpartum depression and its predictors at six months postpartum. Methods: The subjects were 161 women six months after delivery who were registered with the public health center. The instruments included a survey of various characteristics, the Edinburgh Postnatal Depression Scale(EPDS), husband support, maternal self-esteem, and marital adjustment scale. The data was analyzed using the $x^2$-test, t-test, the Pearson correlation coefficients, and the logistic regression. Results: The point prevalence of postpartum depression at six months postpartum was 14.3%, corresponding to a score of 12 or higher on the EPDS. Postpartum depression was significantly associated with husband support, maternal self-esteem, and marital adjustment. Predictors of postpartum depression identified by the logistic regression analysis include marital adjustment (OR .29 [95% CI .13-.61]) and the delivery method(OR 3.57 [95% CI 1.25-10.23]). Conclusion: Strategies for improving postpartum depression, considerations of husband support and maternal self-esteem are important in research and practice. In addition, interventions for reducing Cesarean delivery and improving marital adjustment are needed.

• 성인간호학회지
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• 제20권1호
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• pp.102-112
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• 2008

Purpose: The purpose of this study was to examine self care behaviors according to the risk levels of vascular complications in elderly women with hypertension. Methods: The subjects of this study were 162 women living in the community who had been diagnosed with hypertension in clinics. The data were analysed by the SPSS 10.0 program using descriptive statistics, t-test, and ANOVA with Scheff$\dot{e}$ post-hoc test. Results: The average self care behavior score of the elderly women was 2.79. Total self care behavior was significantly different depending on the risk levels of vascular complications such as systolic blood pressure, diastolic blood pressure, ankle-brachial index, and the framingham point score. Among sub-scores of self care behaviors, exercise management was the poorest performance compared with other self care behaviors. Conclusion: This study proved the differences in self care behaviors according to the risk levels of vascular complications. To decrease the prevalence of vascular complication, it is necessary to develop programs specifically to enhance self care behaviors of elderly women with hypertension.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5449-5454
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• 2013

Background: A large variety of familiar and non-familiar lung carcinomas (LC) are caused by long term exposure to chemical carcinogens that are present in tobacco smoke. We aimed to investigate the prevalence of 5 thrombophilic germ-line mutations in patients with lung carcinomas. Materials and Methods:A total of 52 LC patients and 212 healthy controls from same population were analyzed for FV Leiden, factor V H1299R (R2), PAI-1, MTHFR C677T, MTHFR A1298C, ACE I/D, and Apo E genes and compared. Results: Overall, heterozygous and/or homozygous point mutations in FV Leiden Apo E2, PAI-1 and MTHFR C677T genes were associated with LC in the current cohort. There was no meaningful association between LC and ACE I/D gene markers. Conclusions: The current results showed that LC is related to combined thrombophilic gene mutations and individuals with homozygosity of 4G in PAI-1 and MTHFR C677T genes and heterozygosity of FV Leiden, Apo E4 genes have a germ-line risk for LC tumorigenesis.

• 대한지역사회영양학회지
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• 제2권2호
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• pp.141-150
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• 1997

This study was designed to investigate the obesity rate with anthropometric indices, nutritional status and serum lipid levels of 260 school children from 5th grade of elementry school residing in Puchon city. Obesity was defined as fat percentage that exceeds 25$\%$. The prevalence rate of obesity were 15.2$\%$ for male and 14.1$\%$ for female. Mean fat percentage, BMI and Rohrer indice of obese male were 30.3$\%$, 21.0 and 150.2 respectively and 28.0$\%$, 21.5 and 151.9 for obese female. Mean serum TG, apo-B of obese female was significantly lower than that of non-obese. Obese male did not show any difference in serum lipid levels. The proportion of students whose serum cholesterol levels exceed 170mg/dI, which is cutoff point of bordeline for coronary artery disease, was 12.0% for male and 15.6$\%$ for female. The major factors affecting nutritional status were the amount of living expense, existence of mother's job and the regularity of having breakfast. Children who's living expense more than 500 thousants Won showed lower intake of Iron, vitamin A, thiamin, niacin and ascorbic acid(p$\ll$0.05). Children who's mothers are having a job were observed with decreased height(p$\ll$0.05). Children having breakfast regularly showed increased BMI and Rohrer indice than those of children having breakfast often of never.

• 대한치과보철학회지
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• 제23권1호
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• pp.137-144
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• 1985

This study was designed to investigate the side shift of orbiting condylar movement by direct measurements from tracings of Denar pantograph. It is well known that side shift has much influence on the articulating surface of teeth. In this study, after locating the ture hinge axis point with Denar hinge axis locatior, the recordings of Mandibular movement were obtained from Denar pantographic recording assembly, and immediate side shift and progressive side shift were measured. For this study, 20 dental studnts who have no missing teeth and no difficulties of mandibular movement and 4 patients who were, treated by occlusal therapy were selected. The results obtained were as follows, 1. The prevalence of immediate side shift was 42%, and the immediate side shift of greater than 0.5mm was only 17%. 2. The mean of immediate side shift (20 of 48) was 0.38mm, that of right lateral excursion (7 of 24) was 0.27mm, and that of left lateral excursion (13 of 24) was 0.44mm. 3. The mean of progressive side shift was $7.21^{\circ}$ that of right lateral excursion was $6.46^{\circ}$, and that of left lateral excursion was $7.96^{\circ}$.

• 대한임상검사과학회지
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• 제38권3호
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• pp.173-178
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• 2006

The production of extended-spectrum ${\beta}$-lactamases ($ESBL_S$) is the main mechanism of bacterial resistance to third-generation cephalosporins and monobactams, whose prevalence varies depending on the different geographical areas. In the last years it has increased notably to the point of being considered a health problem of great importance. The characterization of the ESBLs producing Klebsiella penumoniae strains present in clinical isolates is time-consuming. I describe here the development of a new system, which consists of a multiplex PCR. I found 51 K. pneumoniae strains to be presumptive strains ESBLs producers by clinical and laboratory standards institute (CLSI) guidelines. The double disc synergy test showed 47 positive K. pneumoniae, which were K. pneumoniae isolates. All ESBLs producing K. pneumoniae strains were resistant to antibiotic amikacin, gentamicin and ciprofloxacin. By multiplex PCR analysis, $bla_{TEM}$ gene in 17 strains 44 $bla_{SHV}$ genes and $bla_{CTX}$ genes in 33 strains were identified. In this study, the multiplex polymerase chain reaction (PCR) assay was a good method to detect and differentiate ESBLs producing K. penumoniae strains in clinical isolates.

• International Journal of Advanced Culture Technology
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• 제9권3호
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• pp.212-220
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• 2021

Method : Using annual statistics of major surgeries provided by the National Health Insurance Corporation, it figured out what changes come in visual acuity by the number of cataract surgeries nationwide plus age, gender, and geriatric disease every 3 years from 2013 to 2019 through joint point regression for statistics. Objective : This study is intended to identify the relationship between geriatric diseases (diabetes, hypertension, obesity) and visual acuity in geriatric cataract surgery patients. Result : First, geriatric diseases of cataract surgery patients were closely related to diabetes, hypertension, obesity, smoking, and drinking. In particular, diabetes, hypertension, and smoking had a high prevalence rate. There was no difference in gender and age. Second, 72% of all geriatric cataract surgeries were performed at the clinic level, and intraocular lens that was used after geriatric cataract surgery accounted for the majority of monofocal intraocular lens as 96.6%. Third, the visual acuity in geriatric cataract surgery patients improved from an average of 0.40 before surgery to 0.06 after surgery, and visual acuity improvement was found in 95% of them. These results suggest that geriatric cataract patients can expect visual acuity stabilization and positive visual acuity improvement through early surgery.

• 정신신체의학
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• 제27권1호
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• pp.1-12
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• 2019

한 종에 속하는 개체의 행동 양상은 다양한 변이를 가진다. 같은 종 내에서 다른 행동적 표현형이 유지되는 현상은 진화적으로 적소 특화나 빈도의존성 선택으로 설명할 수 있는데, 아직 명확하게 밝혀진 것은 아니다. 특히 극단적인 행동 양상으로서의 정신병리가 높은 비율로 관찰되는 현상은 진화심리학의 난제 중 하나다. 행동 양상의 다양한 변이 및 정신병리를 진화적인 견지에서 접근하기 위한 몇 가지 틀이 제안될 수 있을 것이다. 본 논문에서는 개체 간 행동 양상 변이에 관한 진화적 접근을 중심으로 동물 모델과 성격 요인모델, DSM-IV 다축 모델, FSD 모델, RDoC 모델 등을 간략하게 설명하고, 그 연구에 적용할 때 예상되는 장단점을 논의하고자 한다.