• Title/Summary/Keyword: Plant Evaluation

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Development of Non-toxic Recombinant Ricin Vaccine and Evaluation of Vaccine Efficacy (독성을 제거한 재조합 리신 백신 개발 및 효능평가)

  • Hyeongseok Yun;Hae-Eun Joe;Dong Hyun Song;Chi Ho Yu;Young-Jo Song;Gyeung Haeng, Hur
    • Journal of the Korea Institute of Military Science and Technology
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    • v.27 no.2
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    • pp.304-310
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    • 2024
  • Ricin is a highly toxic protein which is produced in the seeds of the castor oil plant. Ricin toxin A chain has ribosomal RNA N-glycosylase activity that irreversibly hydrolyses the N-glycosidic bond of the adenine residue at position 4324 within the 28S rRNA. In this study, we developed non-toxic recombinant ricin vaccine(R51) in E. coli expression system, and evaluated efficacy of the R51 according to adjuvants. When the R51 was administered using aluminum hydroxide as an adjuvant, the vaccine efficacy was higher than that of TLR agonists or aluminum phosphate. Because it is time-consuming to administer the vaccine three times at three-week intervals, we investigated the survival rate and antibody titer of mice according to the change of time interval of vaccination. Interestingly, there was no difference in survival rate and antibody titer when R51 was administered at 0, 1, and 3 weeks or 0, 2, and 4 weeks compared to when administered at 0, 3, and 6 weeks. Therefore, the developed R51 vaccine is promising to protect soldiers from Ricin attack.

Evaluation of Edge-Based Data Collection System through Time Series Data Optimization Techniques and Universal Benchmark Development (수집 데이터 기반 경량 이상 데이터 감지 알림 시스템 개발)

  • Woojin Cho;Jae-hoi Gu
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.1
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    • pp.453-458
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    • 2024
  • Due to global issues such as climate crisis and rising energy costs, there is an increasing focus on energy conservation and management. In the case of South Korea, approximately 53.5% of the total energy consumption comes from industrial complexes. In order to address this, we aimed to improve issues through the 'Shared Network Utility Plant' among companies using similar energy utilities to find energy-saving points. For effective energy conservation, various techniques are utilized, and stable data supply is crucial for the reliable operation of factories. Many anomaly detection and alert systems for checking the stability of data supply were dependent on Energy Management Systems (EMS), which had limitations. The construction of an EMS involves large-scale systems, making it difficult to implement in small factories with spatial and energy constraints. In this paper, we aim to overcome these challenges by constructing a data collection system and anomaly detection alert system on embedded devices that consume minimal space and power. We explore the possibilities of utilizing anomaly detection alert systems in typical institutions for data collection and study the construction process.

Prospects of omics-driven synthetic biology for sustainable agriculture

  • Soyoung Park;Sung-Dug Oh;Vimalraj Mani;Jin A Kim;Kihun Ha;Soo-Kwon Park;Kijong Lee
    • Korean Journal of Agricultural Science
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    • v.49 no.4
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    • pp.749-760
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    • 2022
  • Omics-driven synthetic biology is a multidisciplinary research field that creates new artificial life by employing genetic components, biological devices, and engineering technique based on genetic knowledge and technological expertise. It is also utilized to make valuable biomaterials with limited production via current organisms faster, more efficient, and in huge quantities. As the bioeconomic age begins, and the global synthetic biology market becomes more competitive, investment in research and development (R&D) and associated sectors has grown considerably. By overcoming the constraints of present biotechnologies through the merging of big data and artificial intelligence technologies, huge ripple effects are envisaged in the pharmaceutical, chemical, and energy industries. In agriculture, synthetic biology is being used to solve current agricultural problems and develop sustainable agricultural systems by increasing crop productivity, implementing low-carbon agriculture, and developing plant-based, high-value-added bio-materials such as vaccines for diagnosing and preventing livestock diseases. As international regulatory debates on synthetic biology are now underway, discussions should also take place in our country for the growth of bioindustries and the dissemination of research findings. Furthermore, the system must be improved to facilitate practical application and to enhance the risk evaluation technology and management system.

Methods for Improving the Function of Habitat and Eco-friendly Use In Urban Area Mountain Parks - Ogeum Neighborhood Park, Seoul - (도섬 산지형공원의 생물서식 기능 및 친자연적 이용을 위한 개선방안 연구 - 서울시 송파구 오금공원을 사례로 -)

  • Hur, Ji-Yeon;Lee, Kyong-Jae;Han, Bong-Ho
    • Journal of the Korean Institute of Landscape Architecture
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    • v.39 no.4
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    • pp.83-97
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    • 2011
  • In this study, space allocation with an assessment system for improving the function of the ecological use and function of each space was undertaken to suggest appropriate goals and directions. Ogeum Park, used as the study site, is a stronghold green zone located in the fan-shaped area of the Songpa-gu green zone on a 22ha area site. The assessment system for this study consisted of a total of 3 steps: Step 1 includes the division of the spatial block, Step 2 assesses the proper functioning of each spatial block, while Step 3 includes space allocation and presents improvements for function by space. This study performed a basin analysis with the consideration that Ogeum Park is a forest area and divided the site into a total of 8 areas according to how the sections of land are used. The function of wildlife habitat included an analysis of plant ecology(vegetation type, vegetation layer, potential vegetation), animal ecology(wild birds), and waterways. The function of leisure and use included an analysis of gradients, noise, paths, status of use, and status of facilities. The evaluation of the function of habitat sorted items into native vegetation, vegetation diversification, vegetation potential, animal diversification and potential of animal habitats. The results of grading the evaluation scores by space in the function of habitat showed that the Areas IV and VII, which were 90% of the maximum point, were Grade A, Areas II and V were Grade B at 70% and Area I and VI were Grade C at 50%. Areas III and VIII, which were not found to be beyond the standard of 50%, were excluded. The evaluation of the functions of leisure and use classified items into use potential, use preference, use concentration, use diversification and use convenience. The results of the graded evaluation scores by space in use function, showed areas V and VI as Grade A, or 90% of the maximum score. Grade B, 70% of the maximum score, was given to Areas I and VII. Grade C, 50% of the maximum score, included Areas II, IV and VIII. Area III, graded lower the standard of 50%, was excluded. The study evaluated areas according to a common standard, classified spaces by proper functions into ecological spaces, environmentally-friendly use spaces and use spaces according to the standard of spatial distribution on the basis of the above results through a synthesis of grades of habitat function, leisure function and use. This offers ideas for the improvement of wildlife habitat and environment-friendly use functions by space.

Development and Application of Landscape Diversity Evaluation Model on the Basis of Rural and Natural Area (농촌 및 자연지역의 경관 다양성 평가모형 개발 및 적용)

  • Ra, Jung-Hwa;Lee, Yong-Eun;Cho, Hyun-Ju;Ku, Ji-Na;Kwon, Oh-Sung
    • Journal of the Korean Institute of Landscape Architecture
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    • v.41 no.6
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    • pp.84-95
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    • 2013
  • Recently, to prevent damage to the landscape, outstanding landscape areas have been designated in advance. In particular, as a fundamental way to evaluate landscape elements, landscape diversity is an important criterion to assess an area with a high conservative value. Therefore, the purpose of this study is to develop a quantitative evaluation model of landscape diversity based on landscape elements and to verify the model by applying it to the study sites. The assessment indicators derived from the literature analysis are topography, vegetation, land-use pattern, and unusual landscape. Topography diversity is subdivided into land undulation and land-form. Vegetation diversity is subdivided into plant community diversity and stratification diversity. To quantitatively analyse each indicator's diversity, SHDI was selected as the central metric. All of the quantitative measures were implemented by using the statistical tool, FRAGSTATS. Through the process of each indicator's standardization and summary, the final landscape diversity index was calculated. The results of the study are significant as it was the initial study of landscape diversity evaluation to seek applicability. However, the results of the Landscape Diversity Evaluation Model in this study based on 4 indicators synthetically demonstrate that more than one or two outstanding indicators can be underrated. Therefore, each 4 assessment indicator results should be considered individually. Furthermore, using the maximum value for each indicator's standardization reflects that it is necessary to analyse various examples to obtain higher objectivity later.

Evaluation of Grassland Grade by Grassland Vegetation Ratio (초지식생비율에 의한 초지등급평가 연구)

  • Lee, Bae Hun;Kim, Ji Yung;Park, Hyung Soo;Sung, Kyung Il;Kim, Byong Wan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.40 no.1
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    • pp.29-36
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    • 2020
  • This study was conducted to suggest the new grassland grade system on evaluating the grassland status. The grassland status has been evaluated based on the forage yield (good, fair and poor) by municipal authorities. The grassland grades by current system were 19 good, 11 fair and 11 poor among the 41 grassland farms from 6 provinces. This evaluation result differed greatly from the result of actual measurement of forage yields which showed all poor. The big difference was resulted from failing the reflection of the various characteristics, such as different seasonal growth and harvest frequency. Furthermore, the lack of consistent examining date and method added the inaccuracy of current grassland grade system. The new grassland grade system based on the grassland vegetation ratio (grass, weed and bare soil) was initially designed into 6-grade system (1st; 100~80%, 2nd; 79~60%, 3rd; 59~40%, 4th; 39~20%; 5th; 19~1% and 6th; 0% on the basis of grasses proportion), but later was changed into 4-grade system (1st, 2nd, 3rd, and 4th grades are 70% or more, 50% or more, 50% or less, and 0% of forage proportion, respectively) after reflecting the opinion of grassland farms and municipal authorities. Re-evaluation on the grassland status using the 4-grade system resulted in the total 80% consisted of 2nd, 3rd and 4th grade which means most grasslands needs the partial reseeding or the rehabilitation of entire grassland. Pictures and schematic diagrams depicting the 4-grade system were presented to improve the objectivity of evaluation. The optimal time for assessing grassland status is fall when plant height 20~30 cm. Conclusively, the 4-grade system is an efficient method for all non-professionals including grassland farms or municipal authorities in assessing the grassland status. To apply this system to the field, the institutional arrangements such as amendment of grassland act should take place in advance.

Recent Progress in Air-Conditioning and Refrigeration Research : A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2015 (설비공학회 분야의 최근 연구 동향 : 2015년 학회지 논문에 대한 종합적 고찰)

  • Lee, Dae-Young;Kim, Sa Ryang;Kim, Hyun-Jung;Kim, Dong-Seon;Park, Jun-Seok;Ihm, Pyeong Chan
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.28 no.6
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    • pp.256-268
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    • 2016
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2015. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. Conclusions are as follows. (1) The research works on the thermal and fluid engineering were carried out in the areas of flow, heat and mass transfer, cooling and heating, and air-conditioning, the renewable energy system and the flow inside building rooms. Research issues dealing with air-conditioning machines and fire and exhausting smoke were reduced. CFD seems to be spreading to more research areas. (2) Research works on heat transfer area were carried out in the categories of heat transfer characteristics, pool boiling and condensing heat transfer and industrial heat exchangers. Researches on heat transfer characteristics included the economic analysis of GHG emission, micro channel heat exchanger, effect of rib angle on thermal performance, the airside performance of fin-and-tube heat exchangers, theoretical analysis of a rotary heat exchanger, heat exchanger in a cryogenic environment, the performance of a cross-flow-type, indirect evaporative cooler made of paper/plastic film. In the area of pool boiling and condensing, the bubble jet loop heat pipe was studied. In the area of industrial heat exchangers, researches were performed on fin-tube heat exchanger, KSTAR PFC and vacuum vessel at baking phase, the performance of small-sized dehumidification rotor, design of gas-injection port of an asymmetric scroll compressor, effect of slot discharge-angle change on exhaust efficiency of range hood system with air curtain. (3) In the field of refrigeration, various studies were carried in the categories of refrigeration cycle, alternative refrigeration/energy system, system control. In the refrigeration cycle category, a cold-climate heat pump system, $CO_2$ cascade systems, ejector cycles and a PCM-based continuous heating system were investigated. In the alternative refrigeration/energy system category, a polymer adsorption heat pump, an alcohol absorption heat pump and a desiccant-based hybrid refrigeration system were investigated. In the system control category, turbo-refrigerator capacity controls and an absorption chiller fault diagnostics were investigated. (4) In building mechanical system research fields, eighteen studies were reported for achieving effective design of the mechanical systems, and also for maximizing the energy efficiency of buildings. The topics of the studies included energy performance, HVAC system, ventilation, and renewable energies, piping in the buildings. Proposed designs, performance tests using numerical methods and experiments provide useful information and key data which can improve the energy efficiency of the buildings. (5) The field of architectural environment was mostly focused on indoor environment and building energy. The main researches of indoor environment were related to the user and location awareness technology applied dimming lighting control system, the lighting performance evaluation for light-shelves, the improvement evaluation of air quality through analysis of ventilation efficiency and the evaluation of airtightness of sliding and LS window systems. The subjects of building energy were worked on the energy saving estimation of existing buildings, the developing model to predict heating energy usage in domestic city area and the performance evaluation of cooling applied with economizer control. The studies were also performed related to the experimental measurement of weight variation and thermal conductivity in polyurethane foam, the development of flame spread prevention system for sandwich panels, the utilization of heat from waste-incineration facility in large-scale horticultural facilities.

A Study on the Determination of Major Evaluation Items and the Preparation of Report when Evaluating the Environmental Impact of Development Projects around Ardeidae Breeding Habitats (백로번식지 주변 개발사업의 환경영향평가시 중점평가항목 선정 및 평가방안 연구)

  • Hye-Ryung Lim;Seon-Gu Kim
    • Journal of Environmental Impact Assessment
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    • v.32 no.1
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    • pp.1-14
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    • 2023
  • When carrying out development projects around Ardeidae breeding habitats, we intend to devise a plan for sustainable coexistence by presenting measures to select and reduce key evaluation items so that conflicts can be prevented in advance at the environmental impact assessment stage. The results of the study are as follows. The main evaluation items are animal and plant items for preservation of Ardeidae breeding habitats and odor and noise items that can evaluate the effects of odors and noise in Ardeidae breeding habitats. First, the scope of the survey in animals and plants categories is not limited to legal guardian species, but includes egrets breeding and feeding grounds corresponding to major species breeding grounds and migratory birds, and preservation measures are established according to the reduction of the area of breeding and feeding grounds. Second, in the odor category, the irradiation period includes the period when the odor generation is the highest from the end of June to the end of July. The odor evaluation standard is based on the complex odor discharge standard, which is a concentration regulation, and the odor concentration felt by humans shall be 2 to 5OU/m3 and the frequency shall be 2% or less. Third, in the noise category, the timing of the survey is measured every month from May to August, including when the sound of egrets and young birds is combined to maximize noise generation. Since the noise of Ardeidae, a bird in summer, occurs only for a certain period of time, measures are taken to reduce noise by securing separation distances, securing buffer green areas, and installing construction rather than installing artificial structures such as soundproof walls. In order for existing Ardeidae breeding sites to maintain an appropriate density of populations and not move populations elsewhere, it is necessary to manage nesting tree and maintain stable habitat quantity and quality.

Soil Testing for Potassium in Upland Soils -Review on the Methodologies- (밭토양(土壤)에 대(對)한 가리(加里) 검정(檢定))

  • Hong, Chong Woon
    • Korean Journal of Soil Science and Fertilizer
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    • v.10 no.3
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    • pp.153-170
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    • 1977
  • Considering the ways for the possible improvement of soil test for upland crops, various methods for the evaluation of K supplying power and testing of available soil K were reviewed in terms of theoretical principles and practical usefulness of the each method. The review was also made on the characteristics of upland crops in K requirement and on the chemical properties of major korean upland and lowland rice soils in terms of K availability. Following is the few remarks drawn from the review. 1. Quite large number of methods have been known for the evaluation of K supplying power and testing for available soil K. In nature, they can be divided into two categories; capacity-based methods and intensity-based methcds. The capacity-based methods usually measure the exchangeable and some portion of nonexchangeable K, while the intensity-based methods suggest to consider the ractivity ratios of major cations in soil solution and the energy requirement for the replacement of exchangeable soil K into soil solution. 2. As methodology for extraction of interested part of soil K, chemical extraction, electrodialysis and ion exchange methods have been known. Among these, chemical extract ion is favorable because of its simplicity. However, recently suggested Electro-Ultra-Filtration method seems to merit further study for wider use for not only K but also other nutrient availability of soils. 3. The intensity-based methods, although they are more theoretical, because of their complexity, in methods may not be adapted for practical soil tests. 4. The exchangeable K which is rather simple to measure and which well reflects the status of K reserve as nonexchangeable and is immediate pool of water soluble K may be good, if not best, criterion of soil K availability to plant in common soil testing. 5. Because there are evidences that the abundance of available K alone may not be good inclication for availability of K to plant, it is recommendable to interprete the exchangeable K data as percent saturation of exchangeable K to total C. E. C. of soil for the recommend ation of K fertilizer based on soil tests. 6. Some pot and field trial results showed the trends that percent potassium saturation to total C. E. C. better serve as the parameter for K fertilizer recommendation.

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Evaluation of Environmental and Economic Impacts of Advanced Wastewater Treatment Plants with Life Cycle Assessment (고도 하수처리장의 전과정평가에 따른 환경성 및 경제성 평가)

  • Pyo, SeHee;Kim, MinJeong;Lee, SeungChul;Yoo, ChangKyoo
    • Korean Chemical Engineering Research
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    • v.52 no.4
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    • pp.503-515
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    • 2014
  • A lot of existing wastewater treatment plants (WWTPs) are rebuilt or retrofitted for advanced wastewater treatment processes to cope with reinforced effluent criteria of nitrogen and phosphorous. Moreover, how to treat the wasted sludge from WWTPs has been also issued since the discharge of the wasted sludge into ocean is impossible from 2011 due to the London Convention 97 protocol. These trend changes of WWTPs get a motivation to assess environmental and economic impacts from the construction stage to the waste stage in WWTPs. Therefore, this study focuses on evaluation of environmental and economic impacts of the advanced wastewater treatment processes and waste sludge treatment process by using life cycle assessment. Four advanced wastewater treatment processes of Anaerobic/Anoxic/Oxic ($A_2O$), 5 stages-Bamard Denitrification Phosphate (Bardenpho), Virginia Initiative Plant (VIP), and Modified University of Cape Town (MUCT) are chosen to compare the conventional activated sludge (CAS) and three waste sludge treatment methods of land fill, incineration, and composting are used. To evaluate environmental and economic impacts of each advanced wastewater treatment processes, life cycle assessment (LCA) and life cycle cost (LCC) are conducted based on International organization for standardization (ISO) guidelines. The results clearly represent that the $A_2O$ process with composting shows 52% reduction in the environmental impact than the CAS process with landfill. On the other hand, the MUCT process with composting is able to save 62% of the life cycle cost comparing with the CAS process with landfill. This result suggested the qualitative and quantitative criteria for evaluating eco-environmental and economic technologies of advanced treatment processes and also sludge treatment method, where their main influence factors on environmental and economic impacts are analyzed, respectively. The proposed method could be useful for selecting the most efficient and eco-friendly wastewater treatment process and sludge treatment method when retrofitting the existing WWTPs to advanced treatments.