• 동의생리병리학회지
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• 제19권5호
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• pp.1137-1141
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• 2005

This paper is written in order to investigate how Lee Je-Ma changed traditional Zhu Xi's philosophical view on Way(Tao; 道) Virtue(De: 德) Nature(Xing;性) and Imperative(Ming; 命), which was general concepts of his contemporary age, to practical philosophy and created new medical theories of Sasang(4 symbols) science from it. Lee emphasized the true thing which is able to be done in one's living not the concepts of Sasang. So he induced the concepts of Way and Virtue from the easy and simple way(易簡之道) in the Classic of Changes(I'Ching) for the purpose of practice by anyone. Because Nature and Imperative are derived from Way and Virtue in the context logically, human life is virtual in itself, so the substance of Nature and Imperative became equal with Way and Virtue. Herein the names and concepts of original 'Sasang' were substituted to Business(事), Mind(心), Body(身), Thing(物) which is able to be directly related with human being in his daily life. And he explained variously about the responses of Mind and Body of individuals onto Business and Thing. So it could be applied in medical aspects like emotional, symptomatical, characteristic features. Conclusively man is virtual being, so Nature and Imperative in the level of Human being are based on Way and Virtue in the level of Heaven. For that reason the new concepts of Sasang Business. Mind. Body Thing or Heaven. Human. Nature and Imperative were proposed.

• 대한한의학방제학회지
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• 제25권4호
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• pp.483-497
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• 2017

Background : Behavioral stress has been suggested as one of the significant factors that is able to disrupt physiological systems and cause depression as well as changes in various body systems. The stressful events can alter cognition, learning, memory and emotional responses, resulting in mental disorders such as depression and anxiety. Results : We used a restraint stress model to evaluate the alteration of behavior and stress-related blood parameter. The animals were randomly divided into two groups of five animals each group. Furthermore, we assessed the change of body weight to evaluate the locomotor activity as well as status of emotional and anxiety in mice. After 7 days of restraint stress, the body weight had significantly decreased in the restraint stress group compared with the control group. We also observed stress-associated behavioral alterations, as there was a significant decrease in open field and forced swim test, whereas the immobilization time was significantly increased in the stress group compared to the control group. We observed the morphological changes of neuronal death and microglia by immunohistochemistry and western blot. In our study restraint stress did not cause change in neuronal cell density in the frontal cortex and CA1 hippocampus region, but there was a trend for an increased COX-2 and iNOS protein expression and microglia (CD11b) in brain, which is restraint stress. Conclusion : Our study, there were significant alterations observed in the behavioral studies. We found that mice undergoing restraint stress changed behavior, confirming the increased expression of inflammatory factors in the brain.

• 한국발생생물학회지:발생과생식
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• 제12권2호
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• pp.117-124
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• 2008

지구상의 모든 생명체들은 자신의 생존과 종의 영속성을 보장하기 위해 우호적이지 않은 환경 변화에 대응하기 위한 효과적인 전략을 발전시켜왔다. 그 결과, 생명체들은 환경요인들의 변화에도 불구하고 체내 생리적 환경의 역동적인 평형, 즉 항상성(homeostasis)을 유지해 나간다. 스트레스는 항상성을 위협하는 정서적 그리고 물리적 반응이다. 스트레스는 일시적일 뿐만 아니라 거의 영구적인 영향을 개체에 줄 수 있는데, 특히 출생전 스트레스는 유전 코드의 변경없이 성체의 기능과 구조를 바꿀 수 있는 '후생학적 프로그래밍'을 할 수 있음이 최근의 연구들에 의해 알려졌다. 본 논문에서는 출생 전 스트레스를 받은 수컷 흰쥐에서 나타나는 생식과 연관된 일련의 사건들, 예를 들어 성적 이형현상을 보이는 뇌 지역의 변화, 신경전달물질 대사의 수정, 생식내분비 상태의 변화, 그리고 마지막으로 성행동의 이상들을 소개한다. 태아의 뇌는 출생전 프로그래밍에 극히 민감한데, 특히 글루코코티코이드는 강력한 뇌-프로그래밍 능력을 갖고 있다. 모체 스트레스에 의해 유도된 글루코코티코이드 입력에 의한 태아 뇌의 지속적인 과도 활성은 신경 가소성을 증가시키는 새로운 프로그램을 제공할 것이다. 그리고 증가한 신경 가소성은 환경 도전 속에서 개체가 더 잘 적응하도록 하는 증가된 표현형의 가소성에 대한 기초가 될 것이다. 결론적으로, '혹독한' 환경을 태아기에 경험한 개체는 미래에 자신의 생존 가능성을 높이기 위해 번식능력을 일부 포기하도록 후생학적으로 (재)프로그램하는 것으로 추정된다.

• 부모자녀건강학회지
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• 제3권2호
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• pp.49-66
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• 2000

Pregnancy is a task of creation in which a women mobilizes her self and the resources available to her in the generation of a new person. Through the pregnancy, a mother has formed the new human relationship with a fetus. Maternal-fetal relationship is considered one of mechanism making the relationship of mother and child. It is important to well-being of mother and fetus, too. The earliest interaction between a mother and her child is during prenatal period. Maternal-fetal dyad is unique and perceived interactions with the fetus make the pregnancy real for the mother. Maternal behavior is "instinctive" and is formed in early childhood by copy of the mother. But, Rubin argues that this behavior is an open intellectual system rather than a prepackaged bundle of traits. There is openness to new learning and a high value placed on knowing which occurs with silent organization in thought. Thus, nurses and other health professionals provide prenatal care that optimally is part of the environment in which the maternal-fetal dyad develops. Thus it is appropriate for nurses to increases their understanding of the dyad and to explore ways to enhance its development. This study focusses on the interaction ability and response of fetus, and the maternal-fetal interaction. The research of fetal responses that involve physiological changes and motor movement have been shown to coccur to both external sensory stimuli and to maternal emotional states. The fetus does also have sensory capacity to be aware of some maternal behaviors, and the motor ability to respond in a way the mother can notice. Thus, very rudimentary interactions appear to be possible. Maternal awareness of fetal activity was supported by several studies. More interesting to the present study are description of maternal-fetal interaction and the finding that there appear to be levels of sensitivity to the fetus involved in maternal-fetal interactions. First, recognition comes that the fetus is separate from the maternal self. Next, the fetus engages in. Lastly, the parent may describe active interaction with the fetus, believing that mother and fetus are communicating on a meaningful level. Several interventions, developed to promote more active interaction between mother and fetus, have been reviewed. In general, the parents were taught to stimulate the fetus and to notice the fetus' responses. This type of intervention might increase the mother's sensitivity to her unborn baby, and she may have a head start toward learning how to res pond sensitivity to the newborn infant. Research In the area of maternal-fetal interaction is scarce. Sensitive behavior is construed as an appropriate and timely response to a signal of need from another person, but no such signal of need can be claimed regarding the fetus. The highest level of maternal-fetal interaction, therefore, might be based more on maternal representations of the imagined fetus than on factual evidence of fetal participation.

• 한국멀티미디어학회지
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• 제9권3_4호
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• pp.27-35
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• 2005

문화컨텐츠의 개발과 관련된 일체의 기술을 CT라고 한다. CT는 문화컨텐츠시장을 둘러싼 여건들의 변화와 더불어 같이 변화해야 한다. 문화컨텐츠 시장이 변화하고 있다. 그 변화는 다섯까지 정도로 요약할 수 있다. 첫째, 문화상품 소비자들의 취향이 감각적으로 변하고 있다. 둘째, 문화상품 소비 경험이 늘어나면서 상품의 인지적(cognitive) 특성에 둔감해지고 있다. 셋째, 소비자들의 문화적 안목의 성장이 공학적 기술의 발전속도를 추월하고 있다. 넷째, 문화산업의 규모가 커지면서 컨텐츠 개발의 목표가 "성공하는 상품"에서 "실패하지 않는 상품"으로 변하고 있다. 다섯째, 문화적 다양성이 높아지고 있다는 점이다. 이런 변화는 문화상품 개발자와 소비자들 간의 감성 차이를 크게 만들어 커다란 감성적 괴리를 만든다. CT에서 감성공학은 이런 문제에 대한 중요한 한 가지 대안이 될 수 있다 감성공학은 체성 감성과 심미적 감성의 배후 원리와 응용기술을 연구하는 분야다. 구체적으로는 이들 감성의 생리적 혹은 심리통계적 지표를 통한 감성측정과 감성을 유발하는 지각적 속성의 파악이 기본이 된다. 이를 토대로 다양한 응용기술을 개발하고 산업화하려 노력한다. 문화컨텐츠 산업에 대한 몇 가지 오해 가운데 하나는 이들 분야가 반짝이는 아이디어 나 어느 개인의 재능 하나로 승부를 걸 수 있는 분야라고 믿는 것이다. 그러나 많은 문화컨텐츠 산업을 면밀히 관찰해보면 그렇지 않다는 것을 알 수 있다. 많은 자본이 들어가거나 세련된 마케팅 기술이 작용하고 있는 경우가 대부분이다. 우리에게는 부족한 요소들이다. 이를 극복하기 위한 방법 가운데 하나가 감성에 대한 과학적이고 공학적인 접근이 될 수 있다. 감성공학은 외국과 견주어 아직까지 나름의 경쟁력을 갖고 있는 분야이기 때문이다.

• 대한간호학회지
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• 제4권1호
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• pp.22-37
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• 1974

Through the examination of hospitalized patient's records, this study purports to determine. the extent to which nursing record behaviors meet general expectations held for nursing records and the differences in nursing record behavior in relation to different nursing categories, period of recording and hospitals with different management patterns. Nursing record behaviors of 802 patient's records in four hospitals in Seoul were examined. by use of a check list, which was prepared by the author as an instrument for the study. Data obtained from this examination were processed into percentage values for percentage. test and chi-square test in order to determine their significance. Results are as follows; 1. Records pertaining to treatment ranked highest among all care categories in their extent of coverage, averaging 65.6 percent. 2. Of the treatment category records, records of medication led others at 94.3 percent. followed by records of test and collection of specimens at 59.9 percent. diet at 58.8 percent and treatment at 41.0 percent. 3. Records in the category of physical assessment and care averaged 44.1 percent, the second highest next to treatment category records, 4. Of the records in the category of physical assessment and care, records in vital signs. placed first at 98.9 percent, followed by sleep at 76.2 percent, body weight at 74.7 percent, symptoms and signs at 69.3 percent, rest at 44.5 percent, hygiene at 39.7 percent, activities and participation at 16.9 percent, positions at 10.3 percent, level of consciousness at 9.8 percent and physiological dysfunction at 1.1 percent in that order. 5. Records in the category of psychological assessment and care averaged 3.2 percent, the lowest of the -three major categories. 6. Of the records in the category of psychological assessment and care, records on emotional responses ranked top at 10.5 percent, followed by self-concern at 2.1 percent, adjustment at 2.0 percent, family, occupational and social relations at 0.7 percent and preferences. and interest at 0.5 percent in that order. 7. Records in relation to the category of specific conditions were found in 9.1 percent of the total records. 8. Of the records in the category of specific conditions, consultation and transfer records, stood first at 25.0 percent, followed by precautionary measurements at 1.4 percent and isolation at 0.9 percent 9. A great difference in nursing record behavior was observed between the first week of hospitalization and the last week, with the first week's recordings much higher than the last week in the categories of treatment and specific conditions (p<0.01). and of physical assessment and care (p <0.05). 10. A big difference was also observed among the hospitals (p<0.01). 11. A big difference was also observed between the government-run hospitals and the private hospitals in the categories of physical assessment and care and specific conditions in the first week of hospitalization (P<0.05l), and in the category of psychological assessment and care in the last week (P<0.05). 12. Between the hospitals established with foreign aid and the other hospitals, the difference in nursing record behavior was significant only in the category of physical assessment and care both in the first week and the last week (P<0.01). 13. The average nursing record behavior in all care categories stood at 45.1 percent in the extent of its coverage in relation to the general expectations.