• Title/Summary/Keyword: Physicochemical function

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Physiochemical Properties and Antibacterial Activities of Metal Complexes of Norfloxacin (노르후록사신-금속이온 착물의 물리화학적 성질 및 항균력)

  • Park, Won-Bong;Kim, Kyung-Ah;Lee, Myung-Hwan;Lee, Dong-Sun;Rho, Dong-Yoon
    • YAKHAK HOEJI
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    • v.36 no.6
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    • pp.577-581
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    • 1992
  • Norfloxacin complexes of $Fe^{2+}$, $Cu^{2+}$ and $Al^{3+}$ have been prepared as solids. The stoichiometry of the complexes has been established. IR investigation indicates the metal-ligating sites in norfloxacin. The bioactivities of complexes all lower than that of norfloxacin. The solubilities and partition coefficients have been measured as a function of temperature. The data are used to evaluate the thermodynamic parameters ${\Delta}G$, ${\Delta}H$, ${\Delta}S$ for the solute transfer process and compared with the parent quinolone, norfloxacin. The existence of such complexes is discussed in the light of quinolone mode-of-action theories.

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Proteomic Approach Analysis of Mammary Membrane Proteins Expression Profiles in Holstein Cows

  • Yang, Yong-xin;Cao, Sui-zhong;Zhang, Yong;Zhao, Xing-xu
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.6
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    • pp.885-892
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    • 2009
  • To investigate host defense mechanisms for protecting the mammary gland from mastitis infection, the membrane fraction of mammary tissues from Holstein cows was purified by differential velocity centrifugation, and then the sodium dodecyl sulfate-polyacrylamid gel electrophoresis (SDS-PAGE) separated proteins were identified by ion trap mass spectrometer equipped with a Surveyor high performance liquid chromatography (HPLC) system. A total of 183 proteins were identified. Bioinformatics software was applied to analyse physicochemical characteristics of the identified proteins and to predict biochemical function. These data may provide valuable information to investigate the mechanisms of mammary gland milk secretion and infectious disease, and enable a clear identification of proteins and potential protein targets for therapies.

Prediction models for compressive strength of concrete with Alkali-activated binders

  • Kar, Arkamitra;Ray, Indrajit;Unnikrishnan, Avinash;Halabe, Udaya B.
    • Computers and Concrete
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    • v.17 no.4
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    • pp.523-539
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    • 2016
  • Alkali-activated binder (AAB) is increasingly being considered as an eco-friendly and sustainable alternative to portland cement (PC). The present study evaluates 30 different AAB mixtures containing fly ash and/or slag activated by sodium hydroxide and sodium silicate by correlating their properties from micro to specimen level using regression. A model is developed to predict compressive strength of AAB as a function of volume fractions of microstructural phases (physicochemical properties) and ultrasonic pulse velocity (elastic properties and density). The predicted models are ranked and then compared with the experimental data. The correlations were found to be quite reasonable (R2 = 0.89) for all the mixtures tested and can be used to estimate the compressive strengths for similar AAB mixtures.

Development and Performance Evaluation of Single screw Polymer Extruder System (단축스크류 고분자압출기 시스템의 개발 및 성능평가)

  • Kim, Jae-Yeol;Jung, Hyo-Hee;Choi, Jin-Ho
    • Tribology and Lubricants
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    • v.25 no.3
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    • pp.182-186
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    • 2009
  • Extruders can be basically divided into bisk and screw type of extruders. Though plastic extruders are often used for its simplicity for water and oil transportation pumps, these days screw extruders are mostly used. Screws are used in many extrusion processes to manufacture complex and complicated shaped parts made of plastics, medicine materials, food, polymer composites, iron and ceramic powders, etc. Also, material correction of deformities is caused by flow and physicochemical reaction phenomenonand material extrusion is processed according to heat transfer. various material comes to hopper because extruder has function by blender and mixing of materials can go well before come out through dice. These change process is so complicated that process condition is decided by trial and error that process condition is underground mainly at extrusion molding process.

A Comparative Study on Litter Decomposition of Emergent Macrophytes in the Littoral Zone of Reservoir

  • Jo, Kang-Hyun;Gong, Hak-Yang
    • Animal cells and systems
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    • v.2 no.3
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    • pp.333-339
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    • 1998
  • Litter decomposition is a key process in energy flow and nutrient cycling in the freshwater littoral zone, and is regulated by physicochemical properties of litters. Using a litterbag method, we compared the decomposition rates of 16 different litter types from 10 plant species of the emergent macrophytes for one year in the littoral zone of the Paltangho Reservoir, Korea. The regression analysis fitted to the various decomposition models showed that mass loss of the litters with time best fitted an asymptotic function. The litters of the emergent macrophytes were composed of two compartments, labile and refractory. The macrophytic litters showed a great variety in decomposition dynamics depending on sources of litters. The labile compartment of the initial litter mass was in a wide range between 18% and 99%, and their decomposition rates varied from 0.0037 to 0.0131 day-1. The decomposition processes of the emergent macrophytes were determined by the relative amounts of the labile and refractory compartments and by the decomposition rate of the habile one in the littoral zone.

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Recent advances of 17O NMR spectroscopy

  • Lin, Yuxi;Kim, Hak Nam;Lee, Young-Ho
    • Journal of the Korean Magnetic Resonance Society
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    • v.23 no.2
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    • pp.56-60
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    • 2019
  • Study on the structure and dynamics of molecules at the atomic level is of great significance for understanding their function and stability as well as roles for various chemico-physical and biological processes. $^{17}O$ NMR spectroscopy has appeared as an elegant technique for investigating of the physicochemical and structural properties of oxygen-containing compounds such as metal organic frameworks and nanosized oxides. This method has drawn much attention as it provides unique insights into the properties of targets based on atomistic information of local oxygen environments which is otherwise difficult to obtain using other methods. In this mini review, we introduce and discuss the recent study and developments of $^{17}O$ NMR techniques which are tailored for the investigation on the structure and dynamics of water and inorganic materials.

Computational approaches for molecular characterization and structure-based functional elucidation of a hypothetical protein from Mycobacterium tuberculosis

  • Abu Saim Mohammad, Saikat
    • Genomics & Informatics
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    • v.21 no.2
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    • pp.25.1-25.12
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    • 2023
  • Adaptation of infections and hosts has resulted in several metabolic mechanisms adopted by intracellular pathogens to combat the defense responses and the lack of fuel during infection. Human tuberculosis caused by Mycobacterium tuberculosis (MTB) is the world's first cause of mortality tied to a single disease. This study aims to characterize and anticipate potential antigen characteristics for promising vaccine candidates for the hypothetical protein of MTB through computational strategies. The protein is associated with the catalyzation of dithiol oxidation and/or disulfide reduction because of the protein's anticipated disulfide oxidoreductase properties. This investigation analyzed the protein's physicochemical characteristics, protein-protein interactions, subcellular locations, anticipated active sites, secondary and tertiary structures, allergenicity, antigenicity, and toxicity properties. The protein has significant active amino acid residues with no allergenicity, elevated antigenicity, and no toxicity.

Physicochemical Characteristics and Carbon Dioxide Absorption Capacities of Alkali-activated Blast-furnace Slag Paste (알칼리 활성화된 고로슬래그 페이스트의 물리화학적 특성 및 이산화탄소 흡수능 평가)

  • Ahn, Hae Young;Park, Cheol Woo;Park, Hee Mun;Song, Ji Hyeon
    • International Journal of Highway Engineering
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    • v.17 no.2
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    • pp.99-105
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    • 2015
  • PURPOSES: In this study, alkali-activated blast-furnace slag (AABFS) was investigated to determine its capacity to absorb carbon dioxide and to demonstrate the feasibility of its use as an alternative to ordinary Portland cement (OPC). In addition, this study was performed to evaluate the influence of the alkali-activator concentration on the absorption capacity and physicochemical characteristics. METHODS: To determine the characteristics of the AABFS as a function of the activator concentration, blast-furnace slag was activated by using calcium hydroxide at mass ratios ranging from 6 to 24%. The AABFS pastes were used to evaluate the carbon dioxide absorption capacity and rate, while the OPC paste was tested under the same conditions for comparison. The changes in the surface morphology and chemical composition before and after the carbon dioxide absorption were analyzed by using SEM and XRF. RESULTS: At an activator concentration of 24%, the AABFS absorbed approximately 42g of carbon dioxide per mass of paste. Meanwhile, the amount of carbon dioxide absorbed onto the OPC was minimal at the same activator concentration, indicating that the AABFS actively absorbed carbon dioxide as a result of the carbonation reaction on its surface. However, the carbon dioxide absorption capacity and rate decreased as the activator concentration increased, because a high concentration of the activator promoted a hydration reaction and formed a dense internal structure, which was confirmed by SEM analysis. The results of the XRF analyses showed that the CaO ratio increased after the carbon dioxide absorption. CONCLUSIONS : The experimental results confirmed that the AABFS was capable of absorbing large amounts of carbon dioxide, suggesting that it can be used as a dry absorbent for carbon capture and sequestration and as a feasible alternative to OPC. In the formation of AABFS, the activator concentration affected the hydration reaction and changed the surface and internal structure, resulting in changes to the carbon dioxide absorption capacity and rate. Accordingly, the activator ratio should be carefully selected to enhance not only the carbon capture capacity but also the physicochemical characteristics of the geopolymer.

Physicochemical Properties and Sensory Score of Hanwoo Beef Loin after Feeding with Mugwort (인진쑥 급여가 한우육의 이화학적·관능적 특성에 미치는 영향)

  • Moon, Yoon-Hee;Jung, In-Chul
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.5
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    • pp.731-737
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    • 2011
  • TMR (total mixed ration) feed was developed by adding mugwort (Artemisia capillaris Thunb.) and was fed to Hanwoo cattle. We investigated the effects of feeding mugwort on the physicochemical properties and sensory scores of the Hanwoo beef, as well as the feasibility of producing beef with high quality and function. Samples included Hanwoo loin fed with fattening cattle TMR feed with (treatment) or without mugwort (control). The content of total catechin in Hanwoo loin fed with the treatment and control was 0.516 and 0.307 mg/kg, respectively, while the content of epicatechin was 0.116 and 0.087 mg/kg, respectively, both of which were significant increase from feeding TMR with mugwort (p<0.05). There was no significant difference between the control and treatment in terms of $b^*$ value, VBN content, EDA, total bacterial numbers, freezing loss, thawing loss, cooking loss, hardness, cohesiveness, gumminess, chewiness, shear force, or sensory score of boiled meat. $L^*$, $a^*$ and pH value for the treatment were significantly higher than the control (p<0.05). TBARS and springiness for the control were significantly higher than the treatment (p<0.05). The aroma of the raw meat and the taste, tenderness, juiciness, and palatability of the roasted meat for the treatment were significantly superior to the control (p<0.05). These results suggest that giving feed containing mugwort inhibits lipid oxidation, increases water holding capacity, and improve sensory scores.

Effects of Mouth Excercise on the Improvements of Oral Function in Elderly Men (노인의 구강기능 향상에 미치는 구강운동의 효과)

  • Jang, Kyeung Ae;Hwang, Inchul
    • Journal of dental hygiene science
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    • v.11 no.3
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    • pp.257-263
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    • 2011
  • The purpose of this study was to examine the effect of a mouth excercise program on the promotion of oral function of old people. Forty seven old persons who conducted a mouth excercise exercise two times every week for 12 weeks in the experimental group were compared with the control group of 39 old persons using physical examinations. The results were as follows; In virtue of this exercise the salivary flow was increased 0.029 ml in the experimental group more than 0.046 ml in the control group. Maximum mouth opening in the experimental group was 4.12 cm and higher than 3.92 cm in the control. Also Oral diadochokinesis was 1.69 times per second in experimental group and more than 1.65 in the control group. Based on the above results, it is concluded that the mouth excercise had good effects on promoting oral health. Some movements of the mouth excercise exercise need be modified, and then the exercise should be publicized as one of the ways to improve wholistic health of the aged.