• Title/Summary/Keyword: Physical model test

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The Analgesic Effect of Aconitum Sinomontanum Nakai Pharmacopuncture in Sprague-Dawley Rats

  • Lee, Jung Hee;Lee, Yun Kyu;Lee, Hyun-Jong;Kim, Jae Soo
    • Journal of Acupuncture Research
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    • v.38 no.2
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    • pp.140-145
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    • 2021
  • Background: Aconitum sinomontanum Nakai (ASN) has been reported to have analgesic effects. In this study an animal model of pharmacopuncture using ASN (100-500 mg/kg) was examined. Methods: Sprague-Dawley (SD) rats (n = 40) were randomly assigned to ASN-Low (1 mg/mL, 1.8 mL, ASN-L), ASN-Intermediate (5 mg/mL, 1.8 mL, ASN-M), ASN-High (10 mg/mL, 1.8 mL, ASN-H), negative control (0.2 mL normal saline), and positive control (0.2 mL 0.5% lidocaine) groups. All experiments were administered to the rats' left hind leg. The analgesic response was assessed by monitoring the physical (hot plate, and von Frey test) and chemical (formalin) responses to pain. Results: All ASN pharmacopuncture groups demonstrated significant differences in pain response to the hot plate test, von Frey test, and formalin test, compared to the control group (p < 0.05). The response of the ASN-M group and ASN-H groups to the hot plate, the formalin, and the von Frey tests were significantly different, compared to the lidocaine group (p < 0.05). Conclusion: ASN pharmacopuncture had a significant analgesic effect on SD rats in response to physical and chemical models of pain.

Control Method to Single Degree or Three Degrees of Freedom for Hybrid Testing (하이브리드 실험을 위한 1 또는 3자유도에 대한 제어 기법)

  • Lee, Jae-Jin;Kang, Dae-Hung;Kim, Sung-Il
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.2409-2421
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    • 2011
  • This paper will present hybrid tests to a one bay-one story steel frame structure under ground excitation. A structure used in this paper for hybrid test, to evaluate performance and behavior, is divided into two models; one is numerical model with one column element, and a truss or a beam element, the other is physical substructural model with one beam-column element. All tests considered one or three degrees of freedom to implement real-time hybrid test, and two control algorithms to control hardware are used; one using MATLAB/Simulink, the other using OpenSees, OpenFresco and xPCTarget. In addition, for real-time data communication between numerical and physical substructural models SCRAMNet was used. The results of hybrid tests were compared with one of numerical analysis of numerical model with fiber force-based beam-column elements using OpenSees. Real-time hybrid tests were implemented for the validation of control system with simple structure, and then it will be extended to hybrid test for higher nonlinear or complex structure later on.

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Estimation of Hydraulic States Caused by Gate Expansion in Asan Bay (아산만 방조제 배수갑문 확장사업에 따른 주변해역 수리현상 변화 검토)

  • Park, Byong-Jun;Lee, Sang-Hwa
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.20 no.2
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    • pp.184-193
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    • 2008
  • The gate expansion was planed to increase discharge capacity of gate structure at sea dike in Asan Bay. So it was estimated for changing of hydraulic states in Pyeongteak Harbor Zone caused by gate expansion, using Delft3D, FLOW-3D and hydraulic physical scale model testing. In result, the influence of gate expansion was indicated to be weak.

Viscoelastic constitutive modeling of asphalt concrete with growing damage

  • Lee, Hyun-Jong;Kim, Y. Richard;Kim, Sun-Hoon
    • Structural Engineering and Mechanics
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    • v.7 no.2
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    • pp.225-240
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    • 1999
  • This paper presents a mechanistic approach to uniaxial viscoelastic constitutive modeling of asphalt concrete that accounts for damage evolution under cyclic loading conditions. An elasticviscoelastic correspondence principle in terms of pseudo variables is applied to separately evaluate viscoelasticity and time-dependent damage growth in asphalt concrete. The time-dependent damage growth in asphalt concrete is modeled by using a damage parameter based on a generalization of microcrack growth law. Internal state variables that describe the hysteretic behavior of asphalt concrete are determined. A constitutive equation in terms of stress and pseudo strain is first established for controlled-strain mode and then transformed to a controlled-stress constitutive equation by simply replacing physical stress and pseudo strain with pseudo stress and physical strain. Tensile uniaxial fatigue tests are performed under the controlled-strain mode to determine model parameters. The constitutive equations in terms of pseudo strain and pseudo stress satisfactorily predict the constitutive behavior of asphalt concrete all the way up to failure under controlled-strain and -stress modes, respectively.

Relationship between Physical Property of Re-agglomerated Floc and Turbulent flow (난류모델을 이용한 재응집 Floc의 물리적 특성 연구)

  • Park, No-Suk;Kim, Seong-Su;Kim, Kwan-Youp;Kim, Jong-Oh
    • Journal of Korean Society of Water and Wastewater
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    • v.24 no.1
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    • pp.103-108
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    • 2010
  • Until now, research reports that it is difficult for brokenup floc after coagulation to reaggregate and settling efficiency of reaggregated floc is relatively low have dominated in water treatment process. In contrast, from recent study conducted by the French researcher, because the density of the reaggregated floc was higher than the previous floc, the settling efficiency of reaggregated floc increased. In this study, 15 times wet test were carried out and the removal efficiency of reagrregated floc was considerably increased. Moreover, this result was explained using the turbulent model for the flow occurred around the floc. Consequently, in the case of suitable hydrodynamic condition for the reaggregation, the characteristics of the reaggregated floc was changed into the favorable condition for improvement of settling efficiency. Also, the most important factor for reaggregation of floc was governed by hydrodynamic shear stress.

Optical Performance Degradation Effects by Fabrication Errors of Circular-type Computer Generated Holograms

  • Kim, Young-Gwang;Rhee, Hyug-Gyo;Ghim, Young-Sik
    • Journal of the Korean Physical Society
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    • v.73 no.11
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    • pp.1657-1662
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    • 2018
  • A null test method which relies on a computer generated hologram (CGH) is widely used to measure a large aspheric surface. For precise measurements of the surface shape of an aspheric optics, the CGH must precisely generate a wavefront that can fit on the ideal surface shape of the aspheric optics. If fabrication errors arise in the CGH, an unwanted wavefront will be generated and the measuring result will lack trustworthiness. Thus far, there has been limited research on wavefronts generated by CGH using only linear-type binary grating models. In this study, a theoretical error model of a circular-type zone plate, the most commonly used types for CGH patterns, is suggested. The proposed error model is checked by simulations and experiments.

A Structural Equation Model of Health-Related Quality of Life among Older Women Following Bilateral Total Knee Replacement (양측 슬관절 전치환술 여성노인의 건강관련 삶의 질 구조모형)

  • Lee, Hyun Ok;Yoo, Jae Soon
    • Journal of Korean Academy of Nursing
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    • v.50 no.4
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    • pp.554-570
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    • 2020
  • Purpose: This study aimed to develop and test a structural equation model of health-related quality of life among older women following bilateral total knee replacement based on a literature review and Wilson and Cleary's model of health-related quality of life. Methods: One hundred ninety three women who were diagnosed with osteoarthritis, were older than 65 years, and were between 13 weeks and 12 months of having a bilateral total knee replacement were recruited from an outpatient clinic. Data were collected from July 2017 to April 2018 using a structured questionnaire and medical records. Data were analyzed using SPSS/WIN 22.0, AMOS 22.0, and Smart PLS 3.2.4. Results: The fitness of the hypothetical model was good, with coefficients of determination (R2) ranging between .28 and .75 and predictive relevance (Q2) between .26 and .73. The standardized root mean square residual of the model fit indices for the hypothetical model was .04; which explained 64.2% of physical and 62.5% of mental health-related quality of life. Self-efficacy, symptom status, functional status, and general health perceptions had a significant direct effect on physical health-related quality of life, while social support, symptom status, and general health perceptions had a significant direct effect on participants' mental-health-related quality of life. Conclusion: To improve the physical and mental quality of life of older women who receive bilateral knee replacement, nursing-based intervention strategies that reduce symptoms, improve functional status, and increase health perceptions, self-efficacy, and social support are needed. The most important factor is the symptom status.

Relationship of Test Methods of Impact Absorbing Effect of Floors from a viewpoint of Safety in Accidental Collisions (인체충돌시 바닥의 안전성에 관한 시험방법간 연관성 분석)

  • Kim, Sang-Heon;Ji, Suk-Won;Yoon, Jung-Sik;Choi, Soo-Kyug;Seo, Chee-Ho
    • Journal of the Korea Institute of Building Construction
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    • v.11 no.1
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    • pp.29-34
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    • 2011
  • Since the study of building performance design was first undertaken by Building Research Station in 1930s, the results of such study has been reported from many parts of the world, building construction codes and standards have been revised based on performance in advanced nations as well in Korea, and various performance certification systems are in operation. The purpose of this study is to build a database of performance certification systems to investigate the co-relationship of various test methods related to the same test items. As test methods for case study, we selected test methods involving collision of the human body. Through analysis of Critical fall height test of EN 1177 and Head Model test of JIS A 6519 about 8 species of floor test-bodies, it was found that there are limits of application in terms of the depth and strength of cushion. Furthermore, although the measured physical parameters are the same, when the co-relationship between test methods is uncertain, the various physical parameters may not be compatible with the results.

The effects of Far-infrared on Type II collagen induced mouse and the relative cytokine computerize programming (Emphasis on TNF-a and IL-1b) (원적외선이 관절염 흰쥐 모델에 미치는 영향과 관련 싸이토카인 예측 프로그래밍)

  • Kim Jae Yoon;Kim Jin-Sang;Bae Sung Soo;Park Rae Joon
    • The Journal of Korean Physical Therapy
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    • v.15 no.1
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    • pp.38-60
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    • 2003
  • The purpose of this study was to observe the effects of Far-infrared on mice rheumatoid arthritis induced by type II collagen. The author peformed several experimental tests which were the hematoxylin-eosin tissue stain, the hind paw thickness, and ELSIA of cytokines(TNF-$\alpha$, IL-1$\beta$). On day 14 and 21, FIR-Tx. group decreased in synovial membrane thickness more than control II group FIR-Tx group decreased in hind paw thickness more than control II group. In the ELISA test of TNF-$\alpha$ concentration, control II group significantly increased in the concentration more than normal and FIR-Tx. group on day 7, 14, and 21. In the ELISA test of IL-$\beta$ concentration, FIR-Tx. group decreased in the concentration more than control II group on day 14 and 21. With J's Linear Function Data Process Program, researchers can get the estimated the concentration or the hind paw thickness from this experiment. The estimated results would be a good guide to therapists and researchers, planning Far-infrared application on the rheumatoid arthritis. These results indicated that far-infrared irradiating appeared to reduce the concentration of TNF-$\alpha$ and IL-1$\beta$ at mouse model of autoimmune arthritis. It would be considered that Far-infrared has an effect on relieving rheumatoid arthritis.

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Virtual Durability Test Procedures and Applications on Design of a Vehicle Suspension Module (자동차 현가모듈의 내구설계를 위한 가상 내구시험기법 정립 및 응용)

  • 손성효;허승진
    • Transactions of the Korean Society of Automotive Engineers
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    • v.11 no.4
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    • pp.144-150
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    • 2003
  • Recently, the virtual test techniques using computer simulation play an important part in the vehicle development procedures in order to reduce the development time and cost by replacing the physical prototypes of the vehicle components or systems with the virtual prototypes. In this paper, virtual durability test procedures for the vehicle suspension module have been developed. Virtual durability test consists of dynamic simulation computing load history of suspension components, fatigue analysis computing the life of components. A vehicle suspension module for dynamic simulation are developed and validated by comparison with the measured data obtained from the field vehicle test. And on the basis of the validated vehicle suspension model, fatigue analysis has been performed for the virtual durability design of the suspension components.