• Journal of Acupuncture Research
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• v.25 no.1
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• pp.97-106
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• 2008

Objectives : This study was designed to evaluate the effects of Bee Venom Pharmacopuncture therapy in patients with lumbar spinal stenosis. Methods : We investigated 16 patients with lumbar spinal stenosis. We divided patients into two groups : Bee Venom Pharmacopuncture was performed with acupuncture therapy for one group, and the other group received acupuncture therapy only. To evaluate the effectiveness of the treatment applied to the two groups, we used the Visual Analog Scale(VAS) and the Oswestry Low-back Pain Disability Index(ODI). We compared the VAS and ODI scores of the two groups statistically. Results : The Bee Venom Pharmacopuncture group received more effective relief than the acupunctureonly group as measured by decreasedpain and disability reported on the VAS and ODI by patients with lumbar spinal stenosis. Conclusions: Bee Venom Pharmacopuncture therapy can be used in addition to acupuncture therapy for highly effective treatment of patients with lumbar spinal stenosis. Further clinical studies are needed to verify these findings.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.9 no.2
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• pp.21-33
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• 2014

Objectives : This study was to report the improvement of the patient with multiple sclerosis treated by Korean Medical treatment. Methods : The patient diagnosed as multiple sclerosis treated by acupuncture, bee venom pharmacupuncture, chuna manual therapy, and herbal medicine. To evaluate the effects of korean medicine, we used manual muscle test(MMT), the standard for assessment of the effect of stroke treatment, functional system(FS), visual analog scale(VAS). Results : 1. The patient's pain and optic dysfunction were reduced by the above therapy. 2. There was no change in manual muscle test(MMT), but there was mild improvement in finger joints function in the standard for assessment of the effect of stroke treatment. 3. In functional system(FS) scale, there was enhancement in optic function within a range. And there was improvement in expanded disability statue scale(EDSS) from 4.0 to 3.0. 4. In visual analog scale(VAS), there was considerable improvement from 9 to 6. Conclusions : The korean medical treatment was reduced pain and optic dysfunction.

• Journal of Korean Medicine Rehabilitation
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• v.32 no.3
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• pp.189-196
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• 2022

The aim of this study was to investigate the effect of complex Korean medicine treatment especially Buja-tang and Aconitum ciliare decaisne pharmacopuncture on patients with type 1 complex regional pain syndrome caused after a traffic accident. The patients was treated with Buja-tang, Aconitum ciliare decaisne pharmacupuncture, acupuncture and physical therapy during 20 days of hospitalization. Numerical rating scale (NRS), short form McGill pain questionnaire (SF-MPQ), body temperature measurement of the foot, manual muscle test (MMT) were used for assessment. After treatments, NRS of burning pain in the left ankle decreased from 8 to 4-5 and NRS of burning pain in the right ankle decreased from 7 to 4-5. Also, SF-MPQ results, foot temperature measurement and MMT showed improvement during hospitalization. This study shows that complex Korean medicine treatment especially Buja-tang and Aconitum ciliare decaisne pharmacopuncture are effective in alleviating symptoms in patients with type 1 complex regional pain syndrome.

• Journal of Acupuncture Research
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• v.25 no.3
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• pp.95-106
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• 2008

Objectives : This study is to evaluate Effect of Hong Hua Za acupuncture anti-inflammatory on rheumatoid arthritis that caused by Lipopolysaccharide in mouse. Methods : Hong Hua Za(Carthami Tinctorii Fructus) acupuncture(HA) was prepared and tested for therapeutic potential of rheumatoid arthritis, by measuring the inhibition of inducible nitric oxide synthase (iNOS) expression, nitric oxide(NO) production in vitro experiment, by measuring Tumpr Necrosis Factor-$\alpha$(TNF-$\alpha$) & Nuclear Factor kappa B(NF-$\kappa$B) p65 activation, synovial hyperplasia, angiogenesis and fibrosis in synovial membrane of knee joint of mice. Results : HA showed therapeutic effects on Lipopolysaccharide(LPS)-induced rheumatoid arthritis. HA inhibited iNOS mRNA and NO in RAW264.7cell of LPS-induced rheumatoid arthritis in a dose dependent manner. HA also showed significant inhibition of TNF-$\alpha$ & NF-$\kappa$B p65, activation, synovial hyperplasia, angiogenesis and fibrosis in synovial membrane of knee joint of mice. Conclusions : These results suggest that HA has an therapeutic effects on LPS induced-rheumatoid arthritis by inhibiting TNF-$\alpha$ activation.

• Journal of Korean Medicine Rehabilitation
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• v.24 no.1
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• pp.119-123
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• 2014

The purpose of this study is to report the effect of combined acupuncture treatment on acute ankle sprain patients. The subjects included in this study were 15 acute ankle sprain patients who visited Jaseng Hospital of Korean Medicine from Oct. 15th, 2012 to Feb. 8th, 2013. We treated 15 patients with combined acupuncture treatment. The treatment consisted of Hwangrunhaedok-tang (Huanglianjiedutang) pharmacupuncture, electroacupuncture (applied to GB39, ST36 on the affected side), acupuncture (applied to TE17, SI6 on the unaffected side with Dong-Qi therapy). To assess the effect of treatment, the numeric rating scale (NRS) was applied before and after treatment. After first combined acupuncture treatment, the NRS scores significantly decreased from $8.33{\pm}0.94$ to $2.26{\pm}0.44$ (p<0.01). We suggested that Combined acupuncture treatment are effective and useful on acute ankle sprain. And, further studies will be needed.

• Journal of Acupuncture Research
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• v.28 no.1
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• pp.45-63
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• 2011

Objectives : The aim of this study is to review papers on adverse events in the course of Oriental Medical treatments in the JKAMS and the JCTKAM. Methods : We searched papers up to December 2010 in the JKAMS and The JCTKAM. Electronic and manual literature searches were performed. Results : 92 papers were retrived in total. Out of these, 62 reported the occurrence of adverse events whereas 30 reported none. Adverse events in treatments were generally transient and mild. However, this result had limitations due to the insufficient number of papers reporting adverse events and the inconsistency in the methodology according to each paper. Conclusions : Reports on adverse events are necessary in clinical research. In future research, organized case reports and systemic reviews should be carried out. Furthermore, prospective studies should be done as well.

• Journal of Acupuncture Research
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• v.26 no.1
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• pp.1-14
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• 2009

Objectives : The purpose of this research was to study the effect of Scolopendrid Pharmacopuncture on frozen shoulder patients. Methods : All of the 46 frozen shoulder patients who visited the department of Acupuncture & Moxibustion in Wonkwang Sanbon Medical Center from 1st March 2007 to 30th August 2008 had taken either the Scolopendrid Pharmacopuncture therapy or acupuncture therapy 10 times. There are 23 patients in each group. We evaluated the improvement of their shoulder pain and disability using the Visual Analog Scale(VAS), Shoulder Pain And Diability Index(SPADI), Range of Motion(ROM), and the Apley Scratch test at their first and last visit. Then we analyzed and compared the improvement shown by the two groups. Results : 1. Measures on all tests for the acupuncture group showed statistically significant improvement. 2. Measures on all tests for Scolopendrid Pharmacopuncture showed statistically significant improvement. 3. The Scolopendrid Pharmacopuncture group's VAS and ROM(external, internal rotation) showed statistically significant difference compared with those of the acupuncture group. SPADI, ROM(flexion, extension, abduction, adduction) and Apley scratch test had no statistically significant difference between the two groups. Conclusions : The above results show that Scolopendrid Pharmacopuncture therapy can be used as an effective treatment for reducing frozen shoulder pain.

• Journal of Acupuncture Research
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• v.26 no.5
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• pp.161-169
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• 2009

Objectives : The purpose of this study was to evaluate Oriental Medicine Therapy on the Lumbosacral plexitis patient. Methods : The patient was treated with dry needle acupuncture, bee venom pharmacupuncture, herb medicine, indirect moxibustion and physical therapy. We estimated S kinds of Symptoms by Visual Analog Scale, lower limb motor grade test, gait condition test and sensory examination to evaluate the effect of Oriental conservative treatment. Results : After treatment, patient's visual analogue scale score were generally decreased 10 to 4 and lower limb muscle power and gait condition were improved. Conclusions : Oriental Medicine Therapy might be an effective method to treat the Lumbosacral plexitis patient who was diagnosed as Wei Symptom. It is necessary to have more observation and many cases of patients with Lumbosacral plexitis.

• Journal of Pharmacopuncture
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• v.11 no.2
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• pp.21-31
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• 2008

Objective This study was performed to investigate whether Bee Venom Pharmacopuncture(BVP) could be a more effective modality than Warm Needling(WN) in relieving pain and symptoms of knee osteoarthritis(OA). Design Prospective, randomized and controlled clinical trial. Setting Single center trial in Korea Patients 49 volunteers with knee OA participated in the study. All the participants were screened through an inclusion and exclusion criteria. 33 participants were completed the clinical trial. Intervention The subjects were randomly assigned to one of two groups. One group received BVP(n=18), while the other group received WN(n=15). Sixteen sessions of BVP or WN were given at the pain region of the problematic knee for 8 weeks. Primary outcome measure is the Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index scores(Korean WOMAC, KWOMAC). Secondary outcome measure is the physical health scores based on the 36-Item Short-Form Health Survey(SF-36) and Patient Global Assessment(PGA). KWOMAC and SF-36 were measured third (baseline, 4 and 8 weeks). PGA was measured twice(4 and 8 weeks). Results BVP group showed significant decrease compared to WN group in pain, function and total scores of KWOMAC according to the Mann-Whitney U-test. In the PGA, BVP group, compared to WN group, showed a significant increase. Conclusions BVP was more effective in relieving pain of knee OA than WN. These findings suggest that BVP is a promising alternative for treating knee OA.

• Journal of Acupuncture Research
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• v.25 no.1
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• pp.1-14
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• 2008

Objectives : Delayed neuronal death(DND) of pyramidal neuronsin the CA1 regions of the hippocampus has been extensively studied following global brain ischemia, whereas little is known about DND in this highly vulnerable brain region after focal brain ischemia. The aim of the present study was to investigate the effect of Gastrodiae Elata(GA) pharmacopuncture on hippocampal neuronal apoptosis in rats with focal brain ischemic injury. Materials and methods : The neuroprotective effects of water extracts of GA were investigated in middle cerebral artery occlusion(MCAo) of Sprague-Dawley(SD) rats. Seventy-five healthy SD ratswere randomly divided into five groups following MCAo : control group with focal ischemia, saline injection group, pharmacopuncture group GA-1($0.0007mg/m{\ell}/g$), pharmacopuncture group GA-2($0.00035mg/m{\ell}/g$), pharmacopuncture group GA-3($0.00014mg/m{\ell}/g$). Results : The intensity of mGluR5 increased in the GA-1 group. The intensity of Bax and the Bax/Bcl-2 ratio decreased in the GA-1 group. The intensity of Bcl-2 increased in all the GA groups. The density of neurons stained by Cresyl violet and ChAT increased in the GA-1 group. Conclusions : Our study suggests that GA pharmacopuncture at $GB_{20}$ showed anti-apoptotic and neuroprotective effects on cholinergic neuronsin focal cerebral ischemia caused by stroke in SD rats.