• Progress in Medical Physics
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• v.27 no.4
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• pp.224-231
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• 2016

The usefulness of Gel Bolus phantom was investigated by comparing the temperature distribution characteristic of the agar phantom produced to investigate the dose distribution characteristic of radiofrequency hyperthermia device with that of the Gel Bolus phantom under conditions similar to those of an agar phantom that can continuously carry out temperature measurement. The temperatures of the agar phantom and the Gel Bolus phantom were raised to $36.5{\pm}3^{\circ}C$ and a temperature sensing was inserted at depths of 5, 10, and 15 cm from the phantom central axis. The temperature increase rate and the coefficient of determination were analyzed while applying output powers of 100 W and 150 W, respectively, at intervals of 1 min for 60 min under conditions where the indoor temperature was in the range $24.5{\sim}27.5^{\circ}C$, humidity was 35~40%, internal cooling temperature of the electrode was $20^{\circ}C$, size of the upper electrode was 250 mm, and the size of the lower electrode was 250 mm. The coefficients of determination of 150 W output power at the depth point of 5 cm from the central axis of the phantom were analyzed to be 0.9946 and 0.9926 in the agar and Gel Bolus phantoms, respectively; moreover, the temperature change equation of the agar and Gel Bolus phantoms with time can be expressed as follows in the state the phantom temperature is raised to $36^{\circ}C:Y(G)$ is equation of Gel Bolus phantoms (in 5 cm depth) applying output power of 150 W. Y(G)=0.157X+36. It can be seen that if the temperature is measured in this case, the Gel Bolus phantom value can be converted to the measured value of the agar phantom. As a result of comparing the temperature distribution characteristics of the agar phantom of a human-body-equivalent material with those of the Gel Bolus phantom that can be continuously used, the usefulness of Gel Bolus phantom was exhibited.

• Journal of Biomedical Engineering Research
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• v.25 no.2
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• pp.89-95
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• 2004

Intensity-modulated radiation therapy (IMRT) often uses small beam segments. The heterogeneity effect is well known for relatively large field sizes used in the conventional radiation treatments. However, this effect is not known in small fields such as the beamlets used in IMRT. There are many factors that can cause errors in the small field i.e. electronic disequilibrium and multiple electron scattering. This study prepared geometrically regular heterogeneous phantoms, and compared the measurements with the calculations using the Convolution/Superposition algorithm and Monte Carlo method for small beams. This study used the BEAM00/EGS4 code to simulate the head of a Varian 2300C/D. The commissioning of a 6MV photon beam were performed from two points of view, the beam profiles and depth doses. The calculated voxel size was 1${\times}$1${\times}$2$\textrm{cm}^2$ with field sizes of 1${\times}$1$\textrm{cm}^2$, 2${\times}$2$\textrm{cm}^2$, and 5${\times}$5$\textrm{cm}^2$. The XiOTM TPS (Treatment Planning System) was used for the calculation using the Convolution/Superposition algorithm. The 6MV photon beam was irradiated to homogeneous (water equivalent) and heterogeneous phantoms (water equivalent ＋ air cavity, water equivalent ＋ bone equivalent). The beam profiles were well matched within :t1 mm and the depth doses were within ${\pm}$2%. In conclusion, the dose calculations of the Convolution/Superposition and Monte Carlo simulations showed good agreement with the film measurements in the small field.

• Journal of Radiation Protection and Research
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• v.29 no.2
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• pp.97-104
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• 2004

MIRD-type Korean adult male phantom, 'KMIRD' was constructed to calculate Korean-specific dosimetric quantities for radiation protection consideration. The external shape of KMIRD was based on national physical standard data of Korean. KMIRD has thicket trunk than MIRD5 and arm models divided from trunk. The height and weight of the KMIRD are 171 cm and 63.8 kg. ICRP23 data were referred to constitute organs and tissues of KMIRD. However nine organs were constructed based on Korean reference data provided by Radiation Health Research Institute. In the present study, the MCNPX2.3 Monte Carlo transport code was combined with KMIRD to calculate dose conversion coefficients for photon in the energy range from 0.05 to 10 MeV. The simulated irradiation geometries are broad parallel photon beams in AP, PA, LLAT and RLAT direction. Absorbed dose conversion coefficients were compared with data calculated with MIRD5, MIRD-type phantom based on ICRP23 reference man. In some organs, the discrepancies between two phantoms amount up to nearly 30%. The effective doses conversion coefficients of KMIRD are lower than those of MIRD5. The dose discrepancies between two MIRD-type phantoms ate because of physical differences between Korean and Western, also geometric differences between two phantoms. KMIRD should be revised using the full set of Korean reference data of all organs. The developed MIRD-type Korean adult male phantom can be applied to dose assessment of internal exposure.

• Journal of Radiation Protection and Research
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• v.28 no.1
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• pp.35-42
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• 2003

Methodology for calculating the organ equivalent doses and the effective doses of pediatric and adult patients undergoing medical X-ray examinations were established. The MIRD-type mathematical phantoms of 4 age groups were constructed with addition of the esophagus to the same phantoms. Two typical examination procedures, chest PA and abdomen AP, were simulated for the pediatric patients as well as the adult as illustrative examples. The results confirmed that patients pick up approximate 0.03 mSv of effective dose from a single chest PA examination, and 0.4 to 1.7 mSv from an abdomen AP examination depending on the ages. For dose calculations where irradiation is made with a limited field, the details of the position, size and shape of the organs and the organ depth from the entrance surface considerably affect the resulting doses. Therefore, it is important to optimize radiation protection by control of X-ray properties and beam examination field. The calculation result, provided in this study, can be used to implement optimization for medical radiation protection.

• Journal of Korean Neurosurgical Society
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• v.62 no.4
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• pp.476-486
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• 2019

Objective : The functional information of $^{11}C$-methionine positron emission tomography (MET-PET) images can be applied for Gamma knife radiosurgery (GKR) and its image quality may affect defining the tumor. This study conducted the phantom-based evaluation for geometric accuracy and functional characteristic of diagnostic MET-PET image co-registered with stereotactic image in Leksell $GammaPlan^{(R)}$ (LGP) and also investigated clinical application of these images in metastatic brain tumors. Methods : Two types of cylindrical acrylic phantoms fabricated in-house were used for this study : the phantom with an array-shaped axial rod insert and the phantom with different sized tube indicators. The phantoms were mounted on the stereotactic frame and scanned using computed tomography (CT), magnetic resonance imaging (MRI), and PET system. Three-dimensional coordinate values on co-registered MET-PET images were compared with those on stereotactic CT image in LGP. MET uptake values of different sized indicators inside phantom were evaluated. We also evaluated the CT and MRI co-registered stereotactic MET-PET images with MR-enhancing volume and PET-metabolic tumor volume (MTV) in 14 metastatic brain tumors. Results : Imaging distortion of MET-PET was maintained stable at less than approximately 3% on mean value. There was no statistical difference in the geometric accuracy according to co-registered reference stereotactic images. In functional characteristic study for MET-PET image, the indicator on the lateral side of the phantom exhibited higher uptake than that on the medial side. This effect decreased as the size of the object increased. In 14 metastatic tumors, the median matching percentage between MR-enhancing volume and PET-MTV was 36.8% on PET/MR fusion images and 39.9% on PET/CT fusion images. Conclusion : The geometric accuracy of the diagnostic MET-PET co-registered with stereotactic MR in LGP is acceptable on phantom-based study. However, the MET-PET images could the limitations in providing exact stereotactic information in clinical study.

• Journal of radiological science and technology
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• v.43 no.6
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• pp.475-480
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• 2020

The purpose of this study was to reconstruct diffusion tensor tractography (DTT) using stem of garlic and asparagus for in vitro phantom of diffusion tensor imaging (DTI), and to compare and evaluate the fractional anisotropy (FA) value and the apparent diffusion coefficient (ADC) value to determine whether it can be used as materials for in vitro phantoms. Among various plant fibers such as stem of garlic, palmae, cotton, asparagus, etc., stem of garlic and asparagus, which are considered to be the most suitable for making phantoms, and whose shape is considered to be the most suitable for making phantoms, were selected and tests were conducted. Holes were made in a plastic bucket at an angle of 0°, 30°, 60°, 90°, and 120°, then tubes were inserted. In the tube, asparagus and stem of garlic were inserted as far in as possible, and the inserted tube was inserted into the center of the heat bathed gelatin to harden. We were able to reproduce DTT images in asparagus and stem of garlic. Fiber tissues of asparagus and stem of garlic did not show complete connectivity, but the reconstructed images of DTT showed good connectivity. The FA values of asparagus in the tubes were 0.198 at 0° (straight), 0.207 at 30°, 0.187 at 60°, 0.231 at 90°, and 0.204 at 120°. In addition, the FA values of stem of garlic in the tubes were 0.235 at 0°, 0.236 at 30°, 0.216 at 60°, 0.218 at 90°, and 0.257 at 120°. The ADC values of asparagus in the tubes were 1.545 at 0°, 1.677 at 30°, 1.629 at 60°, 1.535 at 90°, and 1.725 at 120°. In addition, the ADC values of stem of garlic in the tubes were 1.252 at 0°, 1.396 at 30°, 1.698 at 60°, 1.756 at 90°, and 1.466 at 120°. For the best expressed DTT reconstruction image, it showed the longest connectivity in the straight line as we hypothesized. In addition, when comparing the FA values and ADC values of fiber tissues of stem of garlic and asparagus, FA value was generally higher in stem of garlic and ADC value was slightly higher in asparagus.

• Nuclear Engineering and Technology
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• v.54 no.2
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• pp.479-485
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• 2022

At the Korea Institute of Radiological and Medical Sciences, physical human phantoms were developed to evaluate various radiation protection quantities, based on the mesh-type reference computational phantoms of the International Commission on Radiological Protection. The physical human phantoms were fabricated such that a radiophotoluminescent glass dosimeter (RPLGD) with a Tin filter, namely GD-352M, could be inserted into them. A Tin filter is used to eliminate the overestimated signals in low-energy photons below 100 keV. The measurement uncertainty of the RPLGD reader system based on GD-352M should be analyzed for obtaining reliable protection quantities before using it for practical applications. Generally, the measurement uncertainty of RPLGD systems without Tin filters is analyzed for quality assurance of radiotherapy units using a high-energy photon beam. However, in this study, the measurement uncertainty of GD-352M was analyzed for evaluating the protection quantities. The measurement uncertainty factors in the RPLGD include the reference irradiation, regression curve, reproducibility, uniformity, energy dependence, and angular dependence, as described by the International Organization for Standardization (ISO). These factors were calculated using the Guide to the Expression of Uncertainty in Measurement method, applying ISO/ASTM standards 51261(2013), 51707(2015), and SS-ISO 22127(2019). The measurement uncertainties of the RPLGD reader system with a coverage factor of k = 2 were calculated to be 9.26% from 0.005 to 1 Gy and 8.16% from 1 to 10 Gy. A blind test was conducted to validate the RPLGD reader system, which demonstrated that the readout doses included blind doses of 0.1, 1, 2, and 5 Gy. Overall, the E_n values were considered satisfactory.

• The Journal of the Acoustical Society of Korea
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• v.40 no.6
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• pp.587-592
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• 2021

Change in the cortical thickness of long bones occurring with aging and osteoporosis is known to be a risk factor for fracture. The present study aims to investigate the dependencies of phase velocities of ultrasonic guided waves on the cortical thickness in 7 soft tissue-bone mimicking phantoms consisting of acrylic plates covered by a 2 mm-thick silicone rubber layer by using the axial transmission technique with a pair of transducers with a center frequency of 200 kHz and a diameter of 12.7 mm. Two distinct propagating waves with different velocities, the First Arriving Signal (FAS) and the Slow Guided Waved (SGW), were consistently observed for all the soft tissue-bone mimicking phantoms. The FAS velocity decreased slightly with increasing thickness, whereas the SGW velocity increased strongly with increasing thickness. The FAS and the SGW velocities were found to be closely consistent with the S0 and the A0 Lamb mode velocities for a free acrylic plate, respectively, suggesting that the presence of the soft tissue mimicking material (2 mm-thick silicone rubber layer) covering the acrylic plates does not influence significantly the velocity measurements.

• Journal of the Korean Society of Radiology
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• v.17 no.6
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• pp.929-937
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• 2023

Human equivalent phantoms manufactured using 3D printers are cheaper and can be manufactured in a short time than conventional human phantoms. However, many phantoms are manufactured with less than 100 % of Infill Density, one of the 3D printer output setting variables. Therefore, this study compared the Bone Phantom CT number, which differs from the ratio of five Infill Density produced using a 3D printer, to the CT number of the actual human body Bone. In addition, the usefulness of the manufactured phantom was evaluated by producing a 100 % elbow joint phantom with Infill Density and setting the Infill Density to 100 % through CT number comparison for each tissue on computed tomography (CT). As a result, the Bone Phantom printed with 100 % Infill Density did not show the most statistically significant difference from the CT number value of the actual human Bone, and the CT number of each tissue did not show a statistically significant difference from the CT number value of each tissue of the actual human elbow joint.

• Journal of the Korean Society of Radiology
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• v.18 no.2
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• pp.135-144
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• 2024

Ultrasonography examination has limitations in quantifying hepatic fat quantification. Therefore, this study aimed to experimentally demonstrate whether changes in signal attenuation during ultrasound imaging can be quantified using simulated hepatic phantoms to assess hepatic fat content. Additionally, we aimed to evaluate the potential of ultrasound imaging for diagnosing hepatic fatty liver by analyzing the relationship between hepatic fat content and signal intensity in ultrasound images. In this study, we developed a total of five stimulated hepatic phantoms by homogeneously mixing water and oil. We confirmed the fat content of the phantoms using magnetic resonance imaging (MRI) and ultrasound imaging, and measured signal intensity according to distance in ultrasound images to analyze the correlation and mean comparison between fat content and signal intensity. We observed that as the fat content increased, the ultrasound penetration intensity decreased, confirming the potential for quantifying hepatic fat content using ultrasound. Additionally, the analysis of the correlation between the measured fat content using MRI and the signal intensity measured in ultrasound images showed a high correlation. Statistical analysis in our study confirmed that as the fat content increased, the slope representing signal during ultrasound imaging (US-GRE) decreased. In this study, it was statistically confirmed that the US-GRE value of ultrasound images gradually decreases as the fat content increases, and it is believed that US-GRE can serve as a biomarker expressing fatty liver content.