• Title/Summary/Keyword: Phantoms

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Development of Polymeric Human Jelly Phantom for Hyper-Thermic Therapy by High Frequency Magnetic Field (고주파 자기장을 이용한 온열요법 치료용의 젤리형 고분자 모의인체)

  • Choi, Chang-Young;Kim, Byung-Hun;Hwang, Young-Jun;Kim, Oh-Young
    • Polymer(Korea)
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    • v.32 no.1
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    • pp.90-93
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    • 2008
  • We developed a variety of polymeric jelly phantoms that can be used in hyperthermia using an electromagnetic wave as an auxiliary cancer therapy. Particularly, using an appropriate material composed of polyethylene, deionized water, and sodium chloride, jelly phantoms for brain was prepared. Also, their electrical properties were characterized by measuring the dielectric constant and conductivity. As the results, overall electrical values of the phantoms decreased with increasing the amount of the components of the materials, excepted for sodium chloride. Additionally, storage characteristics of the phantoms showed a sustainable stability up to 6 months. Based on the experimental results, it can be proposed that jelly phantoms containing a ferro-magnetic particle could be a potential material for cancer therapy following the further study on the temperature elevation effect and the evaluation of electromagnetic properties of the materials.

Analysis of Properties and Phantom Design Based on Plastic Hardener and Softener for Ultrasonic Imaging (초음파 영상용 플라스틱 기반의 팬텀제작 및 특성 분석)

  • Lee, G.J.;Park, D.H.;Shin, T.M.;Seo, J.B.
    • Journal of Biomedical Engineering Research
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    • v.29 no.4
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    • pp.302-306
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    • 2008
  • Plastic hardener and softener based ultrasound phantoms were made in various constitutions and their acoustic properties were measured. Speed of sound is approximately $1.4\;mm/{\mu}sec$ in all the phantoms, which is about 7% less than that of in soft tissue. Attenuation coefficient is strongly dependent on the ratio between hardener and softener. In order to achieve the tissue level attenuation (0.5 dB/cm/MHz), 60% of hardener or less is required. The synthesized phantoms can be preserved for more than 6 months without structural degradation.

Estimation of Attenuation Coefficient based on Ultrasonic Image for quantification of the Liver Diseases (간 병변의 정량화를 위한 초음파 영상 신호의 감쇄상수 추정)

  • 우광방;신동호;이성모;신영민;이노성;오성권
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.25 no.1
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    • pp.49-55
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    • 1988
  • To provide a quantitative parameter of evaluating diagnosis of the liver diseases accurately, the ultrasonic attenuation coefficient was estimated from liver phantoms, 15 normal human livers and 30 liver disease patients. Two kind of phantoms(No.1: 1552m/s, No.2: 1562m/s) which have velocity (1560m/s) similar to that in human liver were constructed and their ultrasonic attenuation coefficients were determined. In this paper the spectral-shift approach and spectral-difference approach were used for estimating ultrasonic attenuation coefficient, \ulcornerdB/Cm.MHz). These two approaches were utilized to esitmate for 15 normal humans without any liver disease and 30 liver disease patients. The results indicate that the two types of phantoms produce the value of near the suggested value of 0.5 and the attenuation coefficients of hepatoma, normal liver, corrhosis, fatty liver and hepatitis show decreasing value in order named, suggesting that the present study can be of clinical value incorrelating the estimated attenuation coefficidents with the liver diseases.

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A Review of Organ Dose Calculation Tools for Patients Undergoing Computed Tomography Scans

  • Lee, Choonsik
    • Journal of Radiation Protection and Research
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    • v.46 no.4
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    • pp.151-159
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    • 2021
  • Background: Computed tomography (CT) is one of the crucial diagnostic tools in modern medicine. However, careful monitoring of radiation dose for CT patients is essential since the procedure involves ionizing radiation, a known carcinogen. Materials and Methods: The most desirable CT dose descriptor for risk analysis is the organ absorbed dose. A variety of CT organ dose calculators currently available were reviewed in this article. Results and Discussion: Key common elements included in CT dose calculators were discussed and compared, such as computational human phantoms, CT scanner models, organ dose database, effective dose calculation methods, tube current modulation modeling, and user interface platforms. Conclusion: It is envisioned that more research needs to be conducted to more accurately map CT coverage on computational human phantoms, to automatically segment organs and tissues for patient-specific dose calculations, and to accurately estimate radiation dose in the cone beam computed tomography process during image-guided radiation therapy.

Development of an open-source GUI computer program for modelling irradiation of multi-segmented phantoms using grid-based system for PHITS

  • Hiroshi Watabe;Kwan Ngok Yu;Nursel Safakatti;Mehrdad Shahmohammadi Beni
    • Nuclear Engineering and Technology
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    • v.55 no.1
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    • pp.373-377
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    • 2023
  • The Monte Carlo (MC) method has become an indispensable part of the nuclear radiation research field. Several widely used and well-known MC packages were developed for simulation of radiation transport and interaction with matter. All these MC packages require users to prepare an input script. The input script can become lengthy for complex models. The process of preparing these input scripts is time-consuming and error-prone. In the present work, we have developed an open-source GUI computer program for modelling radiation transport and interaction in multi-segmented slab phantoms using grid-based system for the widely used PHITS MC package. The developed tools would be useful for future users of PHITS MC package and particularly inexperienced users. The present program is distributed under GPL license and all users can freely download, modify and redistribute the program without any restrictions.

Effects of CT Contrast Medium on the Relaxation Rate of MR Contrast Medium (CT 조영제가 MR 조영제의 이완율에 미치는 영향)

  • Kwon, Soon-Yong;Kang, Chung-Hwan;Jeong, Hyeon Keum;Park, Jin Seo;Kim, Seong-Ho
    • Journal of radiological science and technology
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    • v.41 no.2
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    • pp.103-107
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    • 2018
  • In MR, the iodine CT contrast medium reduces the T1 and T2 relaxation times of the substance, resulting in a change in signal intensity. This study aimed to measure the relaxation rate of MR contrast medium with or without diluting CT contrast medium and analyzed the effect of CT contrast medium. Undiluted Gadoteridol solution was diluted with saline to prepare MR contrast medium phantoms with various levels of Gadoteridol concentrations. Moreover, undiluted Iomeprol was mixed with the prepared MR contrast medium phantoms at 1:1 ratio to make MR contrast medium phantoms with containing CT contrast medium for the experiment. T1 and T2 mappings were conducted to quantitatively evaluate the relaxation time and relaxation rate of these phantoms. The results showed that the T1 and T2 relaxation time and relaxation rate of MR contrast medium diluted with CT contrast medium were significantly (p<0.05) shorter than those of MR contrast medium not diluted with CT contrast medium. The results of this study imply that, when MR contrast medium shall be used after injecting CT contrast medium, CT contrast medium should be discharged enough. Moreover, it would be desirable to conduct CT test after taking MRI test in order to reduce the effects of CT contrast medium on MR contrast medium.

Dose coefficients of mesh-type ICRP reference computational phantoms for external exposures of neutrons, protons, and helium ions

  • Yeom, Yeon Soo;Choi, Chansoo;Han, Haegin;Shin, Bangho;Nguyen, Thang Tat;Han, Min Cheol;Kim, Chan Hyeong;Lee, Choonsik
    • Nuclear Engineering and Technology
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    • v.52 no.7
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    • pp.1545-1556
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    • 2020
  • Recently, the International Commission on Radiological Protection (ICRP) has developed the Mesh-type Reference Computational Phantoms (MRCPs) for adult male and female to overcome the limitations of the current Voxel-type Reference Computational Phantoms (VRCPs) described in ICRP Publication 110 due to the limited voxel resolutions and the nature of voxel geometry. In our previous study, the MRCPs were used to calculate the dose coefficients (DCs) for idealized external exposures of photons and electrons. The present study is an extension of the previous study to include three additional particles (i.e., neutrons, protons, and helium ions) into the DC library by conducting Monte Carlo radiation transport simulations with the Geant4 code. The calculated MRCP DCs were compared with the reference DCs of ICRP Publication 116 which are based on the VRCPs, to appreciate the impact of the new reference phantoms on the DC values. We found that the MRCP DCs of organ/tissue doses and effective doses were generally similar to the ICRP-116 DCs for neutrons, whereas there were significant DC differences up to several orders of magnitude for protons and helium ions due mainly to the improved representation of the detailed anatomical structures in the MRCPs over the VRCPs.

Properties of Water Substitute Solid Phantoms for Electron Dosimetry

  • Saitoh, Hidetoshi;Tomaru, Teizo;Fujisaki, Tatsuya;Abe, Shinji;Myojoyama, Atsushi;Fukuda, Kenichi
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.255-259
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    • 2002
  • To reduce the uncertainty in the calibration of radiation beams, absorbed dose to water for high energy electrons is recommended as the standards and reference absorbed dose by AAPM Report no.51 and IAEA Technical Reports no.398. In these recommendations, water is, defined as the reference medium, however, the water substitute solid phantoms are discouraged. Nevertheless, when accurate chamber positioning in water is not possible, or when no waterproof chamber is available, their use is permitted at beam qualities R$\_$50/ < 4 g/cm$^2$ (E$\_$0/ < 10 MeV). For the electron dosimetry using solid phantom, a depth-scaling factor is used for the conversion of depth in solid phantoms to depth in water, and a fluence-scaling factor is used for the conversion of ionization chamber reading in plastic phantom to reading in water. In this work, the properties, especially depth-scaling factors c$\_$p1/ and fluence-scaling factors h$\_$pl/ of several commercially available water substitute solid phantoms were determined, and the electron dosimetry using these scaling method was evaluated. As a result, it is obviously that dose-distribution in solid phantom can be converted to appropriate dose-distribution in water by means of IAEA depth-scaling.

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Radiation Dose from Computed Tomography Scans for Korean Pediatric and Adult Patients

  • Won, Tristan;Lee, Ae-Kyoung;Choi, Hyung-do;Lee, Choonsik
    • Journal of Radiation Protection and Research
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    • v.46 no.3
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    • pp.98-105
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    • 2021
  • Background: In recent events of the coronavirus disease 2019 (COVID-19) pandemic, computed tomography (CT) scans are being globally used as a complement to the reverse-transcription polymerase chain reaction (RT-PCR) tests. It will be important to be aware of major organ dose levels, which are more relevant quantity to derive potential long-term adverse effect, for Korean pediatric and adult patients undergoing CT for COVID-19. Materials and Methods: We calculated organ dose conversion coefficients for Korean pediatric and adult CT patients directly from Korean pediatric and adult computational phantoms combined with Monte Carlo radiation transport techniques. We then estimated major organ doses delivered to the Korean child and adult patients undergoing CT for COVID-19 combining the dose conversion coefficients and the international survey data. We also compared our Korean dose conversion coefficients with those from Caucasian reference pediatric and adult phantoms. Results and Discussion: Based on the dose conversion coefficients we established in this study and the international survey data of COVID-19-related CT scans, we found that Korean 7-year-old child and adult males may receive about 4-32 mGy and 3-21 mGy of lung dose, respectively. We learned that the lung dose conversion coefficient for the Korean child phantom was up to 1.5-fold greater than that for the Korean adult phantom. We also found no substantial difference in dose conversion coefficients between Korean and Caucasian phantoms. Conclusion: We estimated radiation dose delivered to the Korean child and adult phantoms undergoing COVID-19-related CT examinations. The dose conversion coefficients derived for different CT scan types can be also used universally for other dosimetry studies concerning Korean CT scans. We also confirmed that the Caucasian-based CT organ dose calculation tools may be used for the Korean population with reasonable accuracy.

Virtual calibration of whole-body counters to consider the size dependency of counting efficiency using Monte Carlo simulations

  • Park, MinSeok;Kim, Han Sung;Yoo, Jaeryong;Kim, Chan Hyeong;Jang, Won Il;Park, Sunhoo
    • Nuclear Engineering and Technology
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    • v.53 no.12
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    • pp.4122-4129
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    • 2021
  • The counting efficiencies obtained using anthropomorphic physical phantoms are generally used in whole-body counting measurements to determine the level of internal contamination in the body. Geometrical discrepancies between phantoms and measured individuals affect the counting efficiency, and thus, considering individual physical characteristics is crucial to improve the accuracy of activity estimates. In the present study, the counting efficiencies of whole-body counting measurements were calculated considering individual physical characteristics by employing Monte Carlo simulation for calibration. The NaI(Tl)-based stand-up and HPGe-based bed type commercial whole-body counters were used for calculating the counting efficiencies. The counting efficiencies were obtained from 19 computational phantoms representing various shapes and sizes of the measured individuals. The discrepancies in the counting efficiencies obtained using the computational and physical phantoms range from 2% to 33%, and the results indicate that the counting efficiency depends on the size of the measured individual. Taking into account the body size, the equations for estimating the counting efficiencies were derived from the relationship between the counting efficiencies and the body-build index of the subject. These equations can aid in minimizing the size dependency of the counting efficiency and provide more accurate measurements of internal contamination in whole-body counting measurements.