• Journal of the Society of Cosmetic Scientists of Korea
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• v.34 no.1
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• pp.43-50
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• 2008

Ceramides, a constituent of stratum corneum lipids, play a crucial role in the formation and maintenance of the epidermal permeability barrier. As in many other skin disorders, atopic dermatitis and psoriasis show decrease and transformation of the ceramides. The application of ceramide has been demonstrated to be efficient in the repair of these skin disorders. Nevertheless, natural ceramides are still too expensive and small in quantity to be used as a cosmetic ingredient. Although a lot of pseudo-ceramides have been developed and on the market until now, those pseudo-ceramides did not fully meet the consumer's needs, therefore, there is still a demand for a novel pseudo-ceramides. We synthesized a novel pseudo-ceramide BPC-16 from 2-(2-amino-ethylamino)-ethanol(AEEA), which was characterized by structures having both amide bonds and hydroxyl groups as hydrophilic units, as well as two long alkyl chains. We formulated emulsion with BPC-16, cholesterol, stearic acid, and other components to make an emulsion. These emulsion showed a typical optical anisotropy on cross-polarized microscopy. This 'Maltese cross' appearance is a characteristic figure observed in concentric lamellar emulsion under cross-polarized microscopy. In cytotoxicity assay using MTT in monolayer and three dimension(3D) cell culture, a BPC-16 showed only negligible cytotoxicity up to the effective concentration for barrier repair and moisturization(less than 10 mM). In the measurement of TEWL, this BPC-16 showed significant recovery of water-retaining properties when it was topically applied to either SDS-induced dry skin or normal skin compared to that of base cream. This novel pseudo-ceramide BPC-16 showed as effective in skin barrier repair and moisturization as natural ceramides.

• Proceedings of the Membrane Society of Korea Conference
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• 1995.09a
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• pp.73-85
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• 1995

The asymmetric hollow fiber membranes were prepared by the wet spining of polyetherimide dope solution and the effect of hollow fiber structures on the permeation characteristics of carbon dioxide and nitrogen gases through these membrane were investigated. As the concentration of the $\gamma$-butyrolactone (GBL) in dope solution, acting as a swelling agent was increased, the structure of hollow fiber was changed from the finger to sponge type. The permeabilities of gases (CO$_{2}$, N$_{2}$) through these membrane were measured over the wide range of pressure under different temperature. The effect of water vapor on the permeabilities of gases was also investigated. The measured permeabilities showed the different characteristics depending on the structure of membranes. It was found that the flow through the pores were dominant over the polymers matrix. Blocking effect by water vapor in the pores of skin layer greatly improved the ideal separation factor of carbon dioxide/nitrogen.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2002.04a
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• pp.407-414
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• 2002

The knowledge of interaction of electromagnetic waves in composite structures is important for designing the shielding structure for antenna such as radome. Recently, radomes are constructed in the form of foam core sandwich structures that have many mechanical advantages such as high strength, long fatigue life, low density and adaptability to the intended function of structure. However, the propagation of electromagnetic waves is affected by high anisotropic permeability and loss tangent of the composite skin. In this study, the analytical model to understand the propagation of electromagnetic waves in the anisotropic composites and foam core sandwich structures with composite skins was proposed. Numerical analyses of unidirectional composites and foam core sandwich structure as a function of incident angle were performed. From the results of analysis, the general tendencies of transmittance of electromagnetic wave through composites and foam core sandwich structure were obtained.

• Journal of the Korean Society of Clothing and Textiles
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• v.21 no.7
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• pp.1153-1161
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• 1997

The insulation provided by clothing system is usually expressed in terms of a coo units and its distribution of the body, directly affect convective, conductive, and radiant heat loss from the skin to the environment Evaporated heat loss is dependent upon fabric permeability, the amount of body surface area covered by clothing, and the pumping of air between the body and garment layers. Persons at low to medium activity levels, dressed in conventional apparel in door environments, usually do not lose a large amount of heat through evaporation. Thermal manikin technology is used to measure the resistance to heat transfer provided by clothing systems. The reciprocal of this value, 6.45 W/m2.$^{\circ}C$ is often used in calculations for convenience. The purpose of this study was to implement a research program for calculation the insulation value (clo), body surface area and basal metabolic rate of selected clothing system. The project provided for the building of an insulation data base for use in evaluating and comparing new and improved garments.

• Proceedings of the Korean Fiber Society Conference
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• 2001.10a
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• pp.115-118
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• 2001

The water vapour permeability of clothing materials is a critical property for clothing systems that must maintain thermal equilibrium for the wearer. The evaporation of perspiration provides the means of cooling the human body. The perspiration should evaporate from the surface of the skin and pass as water vapour through the clothing, which must be permeable for comfort. The primary objectives in this study of the transfer through fabrics of water vapour are to measure this property in a quantitative manner appropriate to clothing systems and to provide an increased understanding of various types of fabric in water vapour transfer. (omitted)

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.20 no.4
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• pp.309-332
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• 2016

Finite element method has been applied to solve the fundamental governing equations of natural convective, electrically conducting, incompressible fluid flow past an infinite vertical plate surrounded by porous medium in presence of thermal radiation, viscous dissipation, Soret and Dufour effects. In this research work, the results of coupled partial differential equations are found numerically by applying finite element technique. The sway of significant parameters such as Soret number, Dufour number, Grashof number for heat and mass transfer, Magnetic field parameter, Thermal radiation parameter, Permeability parameter on velocity, temperature and concentration evaluations in the boundary layer region are examined in detail and the results are shown in graphically. Furthermore, the effect of these parameters on local skin friction coefficient, local Nusselt number and Sherwood numbers is also investigated. A very good agreement is noticed between the present results and previous published works in some limiting cases.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.20 no.4
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• pp.355-374
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• 2016

This work is devoted to investigate heat and mass transfer effects on MHD natural convection flow past an inclined plate with ramped temperature numerically. The dimensionless governing equations for this investigation are solved by using finite element method. The effects of angle inclination, buoyancy ratio parameter, permeability parameter, magnetic parameter, Prandtl number, heat generation, thermal radiation, Eckert number, Schmidt number, chemical reaction parameter and time on velocity, temperature and concentration fields are studied and presented with the aid of figures. The effects of the pertinent parameters on skin friction, rate of heat transfer and mass transfer coefficients are presented in tabular form. The numerical results are compared graphically with previously published result as special case of the present investigation and results found to be in good agreement.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.339-341
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• 2007

Soft ferromagnetic materials are very useful for many sensors using magnetic materials with high permeability, low coercivity and low hysteresis loss. Among them, FeCoSiBNi amorphous magnetic films show us a good impedance change(about 3.05%/Oe, at 12MHz) by the exterior magnetic field in this experiment. These are produced by rapid solidification from the melt and the material is ejected in a jet from a nozzle and quenched in a stream of liquid. After that, we make them a shape of wire with different sizes of width. Thus, we can find that the impedance change (122.16%, at 12MHz) is occurred and the fabricated magnetic wire has the characteristics of good sensor element.

• Journal of Life Science
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• v.15 no.2 s.69
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• pp.267-272
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• 2005

The objective of this study is to suggest the potentialities of nanoliposome composed of ceramide as an anti-irritant against various irritants used in cosmetics. Ceramides are major structural components of the epidermal permeability barrier, which is known to play an essential part in human physiology by not only preventing the loss of water from the body but also protecting the body from external physical, chemical, and microbial insults. According to the results, better effects on reinforcement of skin barrier function and anti-irritation were obtained with nanoliposome composed of ceramide than with dispersed ceramide. And, we performed in vitro skin penetration test using horizontal Franz diffusion cells with skin membrane prepared from hairless mouse to evaluate the influence of nanoliposome composed of ceramide on the skin penetration of lactic acid in formulations. From the results, we found that the anti-irritation effects of nanoliposome containing ceramide were due to reduced penetration rate of irritants. Conclusively, we could develop a new anti-irritation system and apply this nanoliposome composed of ceramide to the final cosmetic products successfully.

• Polymer(Korea)
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• v.36 no.6
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• pp.705-711
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• 2012

In this study, the elastic liposome consisted of egg phospholipids and edge activator ($Tego^{(R)}$ care 450) was prepared in order to supplement the defect of the conventional liposome. We prepared elastic liposome containing quercetin, known as natural antioxidant, and evaluated the vesicles size, elasticity, loading efficiency, stability, and in vitro skin permeation. The mean diameter of quercetin loaded elastic liposome formulations ranged between 208.2~303.4 nm and loading efficiency was observed 64.1~87.5%. The highest loading efficiency (87.5%) and deformability (28.3) were observed at the optimal ratio of 90 : 10 (egg phospholipids : $Tego^{(R)}$ care 450) among 0.1% quercetin loaded elastic liposome formulations. The elastic liposome formulation was selected for further transdermal permeation study. The elastic liposome ($129.9{\mu}g/cm^2$) exhibited more skin permeability than general liposome ($114.8{\mu}g/cm^2$) and 1,3-butylene glycol ($75.1{\mu}g/cm^2$) solution. This results suggest that the elastic liposome formulation using $Tego^{(R)}$ care 450 as a major edge activator could be useful for the delivery of active ingredient through the skin transdermal.