• 대한방사선치료학회지
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• 제30권1_2호
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• pp.139-151
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• 2018

목 적 : "Yaw방향의 보정이 가능한 Tomotherapy couch device"를 자체 제작하였고, 그 유용성을 평가하였다. 대상 및 방법 : 휨 강도가 $200kg/cm^2$의 경질 섬유판 재질로 Yaw방향의 회전 가능한 Tomotherapy couch device를 제작하고, 제작된 device의 물리적 정확성을 판단하기 위해 Varian사의 Novalis Tx의 CBCT Image와 MED-TEC사의 Iso-Align Phantom을 사용하여 device의 Yaw방향의 보정각도의 정확성을 측정하였고, Tomotherapy HDA에서의 치료를 위해 치료계획은 Accuray PrecisionTM를 이용하여 In House Head and Phantom 위에 치료계획을 설계하였고 제작한 device의 보정각도마다 치료 전 후의 MVCT의 adaptive plan을 Accuray PrecisionARTTM and PrecisionTM을 사용하여 선량을 평가하였다. 결 과 : Yaw방향의 보정이 가능한 Tomotherapy couch device를 자체 제작하였으며, 물리적 정확성의 측면에서 모든 각도별 vertical, lateral, longitudinal의 보정값은 약 1 mm 내외였고, 최대 보정값이 1.5 mm를 넘지 않았으며 Yaw방향의 보정은 최대 0.12도 오차 이내의 범위 안에 들어왔다. 치료후의 MVCT촬영 영상을 이용한 adaptive plan을 이용한 선량 평가에서도 모든 각도실험에서 target은 D95=Prescription dose를 만족하고, target내 선량이 95 %~107 % 이내에 들어왔으며, OAR 또한 본원에서 평가한 SMC Head and Neck tolerance dose 영역 내에 모두 들어왔다. 결 론 : 자체 제작한 "Yaw방향의 보정이 가능한 Tomotherapy couch device는 Tomotherapy의 치료에서 Yaw방향의 set-up 오차를 정확히 보정해준다. 비용적인 측면에서도 효과대비 저비용으로 장치를 만들 수 있을 뿐만 아니라 재촬영에 대한 환자가 받는 MVCT image dose를 방지하고 시간적으로도 환자의 회전율을 상승시킬 수 있으며, Yaw방향의 set up 오차를 보정하므로 더 정확한 방사선치료를 시행할 수 있다고 판단된다.

• Journal of Radiation Protection and Research
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• 제42권1호
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• pp.9-15
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• 2017

Background: The purpose of this study is to assign an appropriate density to virtual phantom for 2D diode array detector with different dose calculation algorithms to guarantee the accuracy of patient-specific QA. Materials and Methods: Ten VMAT plans with 6 MV photon beam and ten VMAT plans with 15 MV photon beam were selected retrospectively. The computed tomography (CT) images of MapCHECK2 with MapPHAN were acquired to design the virtual phantom images. For all plans, dose distributions were calculated for the virtual phantoms with four different materials by AAA and AXB algorithms. The four materials were polystyrene, 455 HU, Jursinic phantom, and PVC. Passing rates for several gamma criteria were calculated by comparing the measured dose distribution with calculated dose distributions of four materials. Results and Discussion: For validation of AXB modeling in clinic, the mean percentages of agreement in the cases of dose difference criteria of 1.0% and 2.0% for 6 MV were $97.2%{\pm}2.3%$, and $99.4%{\pm}1.1%$, respectively while those for 15 MV were $98.5%{\pm}0.85%$ and $99.8%{\pm}0.2%$, respectively. In the case of 2%/2 mm, all mean passing rates were more than 96.0% and 97.2% for 6 MV and 15 MV, respectively, regardless of the virtual phantoms of different materials and dose calculation algorithms. The passing rates in all criteria slightly increased for AXB as well as AAA when using 455 HU rather than polystyrene. Conclusion: The virtual phantom which had a 455 HU values showed high passing rates for all gamma criteria. To guarantee the accuracy of patent-specific VMAT QA, each institution should fine-tune the mass density or HU values of this device.

• Journal of Chest Surgery
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• 제39권11호
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• pp.854-857
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• 2006

환자는 8세 여자 환자로 확장성 심근병증을 진단 받은 환자이다. 환자는 심부전으로 인하여 양심실 순환보조를 15일간 시행하였다. 15일 중 후반기 7일은 급성 신부전증이 발생하여 지속적 정맥-정맥간 혈액투석을 시행하였다. 이후 뇌사상태의 A형 혈액형을 가진 심장 공여자에게서 심장을 이식받아 심장이식술을 시행하였다. 면역 억제제는 급성 신부전증을 고려하여 사용하였다. 신부전 상해는 2주간 지속되었고, 심장 이식술 후 약 14일 후 배뇨가 시작되었다. 환자는 수술 후 12일째에 시행한 우심실 조직검사에서 특별한 거부반응의 증거가 없었으며, 면역요법 후 수술 후 52일째에 특별한 문제 없이 퇴원하였다. 환자는 술 후 약 14개월간 조직검사에서 면역 거부반응 없이 외래 경과관찰 중이다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2006년도 제33회 추계학술대회 발표논문집
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• pp.142-142
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• 2006

• International Journal of Heart Failure
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• 제6권2호
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• pp.76-81
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• 2024

Background and Objectives: Real-world clinical data, outside of clinical trials and expert centers, on adverse events related to the use of SyncCardia total artificial heart (TAH) remain limited. We aim to analyze adverse events related to the use of SynCardia TAH reported to the Food and Drug Administration (FDA)'s Manufacturers and User Defined Experience (MAUDE) database. Methods: We reviewed the FDA's MAUDE database for any adverse events involving the use of SynCardia TAH from 1/01/2012 to 9/30/2020. All the events were independently reviewed by three physicians. Results: A total of 1,512 adverse events were identified in 453 "injury and death" reports in the MAUDE database. The most common adverse events reported were infection (20.2%) and device malfunction (20.1%). These were followed by bleeding events (16.5%), respiratory failure (10.1%), cerebrovascular accident (CVA)/other neurological dysfunction (8.7%), renal dysfunction (7.5%), hepatic dysfunction (2.2%), thromboembolic events (1.8%), pericardial effusion (1.8%), and hemolysis (1%). Death was reported in 49.4% of all the reported cases (n=224/453). The most common cause of death was multiorgan failure (n=73, 32.6%), followed by CVA/other non-specific neurological dysfunction (n=44, 19.7%), sepsis (n=24, 10.7%), withdrawal of support (n=20, 8.9%), device malfunction (n=11, 4.9%), bleeding (n=7, 3.1%), respiratory failure (n=7, 3.1%), gastrointestinal disorder (n=6, 2.7%), and cardiomyopathy (n=3, 1.3%). Conclusions: Infection was the most common adverse event following the implantation of TAH. Most of the deaths reported were due to multiorgan failure. Early recognition and management of any possible adverse events after the TAH implantation are essential to improve the procedural outcome and patient survival.

• 보건행정학회지
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• 제14권4호
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• pp.48-74
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• 2004

Considering the existence of asymmetric information between doctor and patient, the doctor's reimbursement method has been considered as a desirable policy device of improving efficiency of patient's use of medical care in terms of its affecting doctor's practice pattern by determining doctor's practice revenue. By using the Community Tracking Study (CTS) physician data set, which includes not only various information on doctors practice arrangements and sources of practice revenue, but also vignettes of various clinical presentations, this paper investigates doctor's reaction to the financial incentive under the control of patient's specific medical situation. Under the econometric model for exploring the effect of doctor's reimbursement method on his/her practice patterns; referring patients, recommend doctor-visit or medical tests, the Hausman's specification test was used for checking out the possibility of the doctor's reimbursement method being endogeneized explanatory variable. In the case where the endogeneity problem of doctor's reimbursement method exists, the 2SLS method was used for correcting that problem, and the multiple regression method was used in the case where the problem is found to be nonexistent. Based on the empirical results, this paper finds that doctors do appear to respond to financial incentive. The empirical results show that the doctor's reimbursement method statistically significantly affects doctor's practice pattern and are coincident with the theoretical result proposed by previous researches, This results suggest, as doctor's practice revenues are mainly determined by prospective method, such as capitation, doctors would more refer their patients to specialists, and hesitate in recommending doctor-visit or medical exam.

• 대한의용생체공학회:의공학회지
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• 제45권1호
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• pp.10-19
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• 2024

The purpose of this study is to conduct a summative evaluation of the usability of a general-purpose ventilator to determine whether it can be used for its intended purpose in the intended environment by the intended user and to find possible errors in use. The importance of ventilators has increased due to the accelerated aging of the population and the impact of the pandemic. In addition, patients who require ventilators are often in critical condition, so even a small error in use can be fatal. Therefore, it is important to ensure that the ventilator has sufficient stability and can be used satisfactorily without inconvenience to the user. In this study, we conducted a usability test with 17 respiratory nurses with more than 3 years of experience using the ventilator. We analyzed the task success rate, satisfaction, and opinions of the intended users while going through a total of 17 scenarios. Satisfaction was captured through an ASQ questionnaire and subjective opinions were captured through a detailed opinion questionnaire. The results showed a high level of satisfaction with an average score of 6.3 for the use scenarios. Evaluators expressed satisfaction with the overall visibility and versatility of the features, but noted that improvements were needed for calibration tasks with low task success rates. As the calibration method is different from other equipment, it was suggested that specific explanations of the calibration method and the picture that appears when calibrating are needed, and that if relevant training is provided, the equipment can be used without problems. If the usability evaluation is not limited to securing efficiency and satisfaction from the intended users, but also continuously receives feedback from users to prepare for use in emergency environments such as pandemic situations, it will be very helpful to seize opportunities such as emergency authorization in future situations, and ultimately contribute to patient safety by reducing use errors.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권3호
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• pp.219-223
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• 2017

In cases of multiple facial trauma and other specific cases, the anesthesiologist may be asked to convert an oral endotracheal tube to a nasal endotracheal tube or vice versa. Conventionally, the patient is simply extubated and the endotracheal tube is re-inserted along either the oral or nasal route. However, the task of airway management can become difficult due to surgical trauma or worsening of the airway condition. Fiberoptic bronchoscopy was considered a novel method of airway conversion but this method is not useful when there are secretions and bleeding in the airway, or if the anesthesiologist is inexperienced in using this device. We report a successful airway conversion under the aid of both, a fiberoptic bronchoscope and a C-MAC video laryngoscope.

• 대한치과보철학회지
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• 제51권4호
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• pp.353-360
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• 2013

구순 구개열은 구강 악안면 부위에 발생하는 선천적 기형이다. 정상적인 연구개는 휴식 시에는 구강과 비강을 연결해 주고, 연하나 특정 발음 시에는 상방으로 이동하여, 구강과 비강을 분리하는 구개인두 폐쇄 운동을 한다. 구개인두 기능부전을 갖는 구개열 환자에서는 이 운동이 불완전하여 저작, 연하, 발음 시에 어려움을 겪는다. 이때, 구개 결손부를 폐쇄하기 위해 사용하는 보철물을 구개 폐쇄장치라고 한다. 구개 폐쇄장치는 구강과 비강을 분리하여 발음, 저작, 연하, 심미적 기능을 회복한다. 본 증례의 환자는 구개인두 기능부전을 갖는 선천적 구개열 환자로 구개인두 폐쇄를 이루기 위하여 모델링 콤파운드와 점막 조정재를 이용한 기능인상 과정을 시행하여 제작한 구개 폐쇄장치를 장착하여 기능적인 면과 심미적인 면에서 만족할만한 결과를 얻었기에 이를 보고하는 바이다.

• Journal of Gastric Cancer
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• 제24권1호
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• pp.108-121
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• 2024

Anastomotic leaks and fistulas are significant complications of gastric surgery that potentially lead to increased postoperative morbidity and mortality. Surgical intervention is reserved for cases with severe symptoms or hemodynamic instability; however, surgery carries a higher risk of complications. With advancements in endoscopic treatment options, endoscopic approaches have emerged as the primary choice for managing these complications. Endoscopic clipping is a traditional method comprising 2 main categories: through-the-scope clips and over-the-scope clips. Through-the-scope clips are user friendly and adaptable to various clinical scenarios, whereas over-the-scope clips can close larger defects. Another promising approach is endoscopic stent insertion, which has shown a high success rate for leak closure, although vigilant monitoring is required to monitor stent migration. Infection control is essential in post-surgical leakage cases, and endoscopic internal drainage provides a relatively safe and noninvasive means to manage fluids, contributing to infection control and wound healing promotion. Endoscopic suturing offers full-thickness wound closure, but requires additional training and endoscopic versatility. As a promising tool, endoscopic vacuum therapy potentially surpasses stent therapy by draining inflammatory materials and closing defects. Furthermore, the use of tissue sealants, such as fibrin glue and cyanoacrylate, has been reported to be effective in selected situations. The choice of endoscopic device should be tailored to individual cases and specific patient conditions, with careful consideration of the nature of the defect. Further extensive studies involving larger patient populations are required to provide more robust evidence on the efficacy of endoscopic approach in managing post-gastric anastomotic leaks.