• Korean Journal of Veterinary Service
• /
• v.23 no.3
• /
• pp.219-221
• /
• 2000

This experiment was done to determine pathological findings of swine dysentery naturally occurred in Korea. Clinical sign was characterized by mucohemorrhagic diarrhea. Characteristic mucofibrinous lesions composed of fibrin, mucus, and sloughed cell debri were mostly limited to the large intestine of affected pjgs. A myriad of coiled spirochetes were detected in the colonic crypts.

• Toxicological Research
• /
• v.18 no.4
• /
• pp.397-400
• /
• 2002

This study was carried out to investigate the acute toxicity of G. bimaculatus in Sprague-Dawley rats. G. bimaculatus was administered orally at doses of 8, 40, 200, 1000 and 5000 mg/kg. in this study, number of deaths, clinical sign, body weights, and pathological examination were investigated for 14 days after administration of G. bimaculatus. The results indicate that G. bimaculatus did not show any toxic effect in rats and oral $LD_{50}$ value was over 5000 mg/kg in Sprague-Dawley rats.

• Korean Journal of Veterinary Research
• /
• v.40 no.2
• /
• pp.333-337
• /
• 2000

This experiment was done to observe the pathological findings of lymphocystis naturally occurred in the cultured flounders in the southern sea of Korea. Anatomical sign of lymphocystis was characterized by the presence of wart-like nodules on the fins, body surface and mouth. Dense clustering of hypertrophic cells originated from fibroblasts was observed in the lesions. Infected hypertrophic cells had a thick hyaline capsule, large vesiculated nucleus with irregular rims and large nucleolus, and large ribbon-shaped basophilic inclusions at the peripheral zone of the cytoplasm. Hexagonal virus particles with the two layers of capsid were scattered throughout the cytoplasm and were absent from the inclusions.

• Toxicological Research
• /
• v.18 no.1
• /
• pp.73-77
• /
• 2002

The single dose toxicity of Hwangiaegongjinbo, an invigorator developed by Korea Medical Science Institute was evaluated in ICR mice and Sprague-Dawley rats. The aqueous solution of freeze-dried powder of Hwangiaegongjinbo or its original solution was once administrated orally to both sexes of mice and rats at dose of 2000 mg/kg, the recommended upper limit dose for acute toxicity. Water was administered to another group as control. after single adminstration, sign of toxicity were observed every hour for the first 6 hours and every day for 14 days. Neither sign그cant toxic sign nor death was observed during the observation period. In addition, no pathological changes were noticed in macroscopic examination at necropsy in those treated group. These results indicated that $LD_{50}$ of Hwangiaegongjinbo is greater than 2000 mg/kg in ICR mice and Sprague-Dawley rats.

• Journal of Chest Surgery
• /
• v.50 no.4
• /
• pp.295-297
• /
• 2017

A 27-year-old man was admitted with a penetrating injury at the mid-manubrium. Computed tomographic (CT) angiography showed a f illing def ect in the aortic arch. This was evaluated as a sign of injury and the patient underwent an emergency operation. No active bleeding or clot was f ound in the mediastinum during the operation. The laceration point was between the innominate and the left carotid artery posteriorly. The injury was approached using hypothermic circulatory arrest. Aortotomy and exploration showed a 2-cm-long full-thickness aortic injury with an overlying clot. A filling defect on angiography as a sign of a penetrating arch injury has never been reported previously, but was the main pathological finding on CT angiography in our case. The aorta is a high-pressure system and injuries to it should be treated aggressively.

• Journal of Korean Physical Therapy Science
• /
• v.16 no.3
• /
• pp.1-9
• /
• 2009

Background: The purpose of this study is to have examined the influence on the blood circulation by comparing the differences between stimulating the sympathetic ganglion and the muscle group among the stimulation variables in interferential current stimulation. Method: The object of the study is the twenties(M=8, F=12), who are in great condition and have no pathological report for the blood circulation influence. The intensity of the inferential current stimulation is the medium degree, 100 bps constant current, which is the comfort and degree to confirm the muscle contraction. The areas stimulated are the stellate ganglion area in the seventh cervical vertebrae and the forearm muscle area. Results: We have made sure that there is no change in blood pressure and pulse and that the change in the skin temperature occurred highly. Conclusion: In considering the change of the blood circulation in case of stimulation area by the inferential current stimulation, we have seen that stimulating the sympathetic ganglion area is more effective than stimulating muscle area directly.

• Korean Journal of Veterinary Service
• /
• v.17 no.2
• /
• pp.83-88
• /
• 1994

The studies were carried out to diagnose of disease chickens that were raised at the chicken farms located in Chung -nam province and evaluated potential of mold growth inhibition of antifungal agent, Mold-X. The diseased 25 chickens that were shown clinical sign such as anorexia, respiratory symptoms, were suspected aspergillosis. The results obtained were summarized as follows ; 1. The diseased thickens were diagnosed aspergillosis according to clinical sign, pathological finding, isolation of etiological agent. 2. The growth of mold was conciderable inhibited by the Mold-X of 300 ppm level.

• Korean Journal of Radiology
• /
• v.21 no.10
• /
• pp.1161-1164
• /
• 2020

The epidemic of 2019 novel coronavirus, later named as coronavirus disease (COVID-19), began in Wuhan, China in December 2019 and has spread rapidly worldwide. Early diagnosis is crucial for the management of the patients with COVID-19, but the gold standard diagnostic test for this infection, the reverse transcriptase polymerase chain reaction, has a low sensitivity and an increased turnaround time. In this scenario, chest computed tomography (CT) could play a key role for an early diagnosis of COVID-19 pneumonia. Here, we have reported a confirmed case of COVID-19 with an atypical CT presentation showing a "double halo sign," which we believe represents the pathological spectrum of this viral pneumonia.

• Journal of the korean veterinary medical association
• /
• v.29 no.9
• /
• pp.513-518
• /
• 1993

The purpose of this study was to report observations of cerebrospinal angiopathy in postweaning piglets which had showed postweaning diarrhea and nervous sign. This disease broke out in 30 to 50day-old piglets on the hog farm which had reared about 1,000

• Sleep Medicine and Psychophysiology
• /
• v.3 no.2
• /
• pp.1-17
• /
• 1996

To demonstrate the clinical usefulness of electroencephalography (EEG) and factors increasing the usefulness of EEG, the authors evaluated each relationship between EEG related factors and clinical variables, and neuroimaging studies (CT and MRI)-related factors, and factors which are related with routine neurological examination for 207 patients who had been evaluated with both of EEG and neuroimaging study(CT or/and MRI). The results were as follows: 1) Abnormality of EEG findings had significant relationships with chief complaints, diagnosis, medication use, seizure attack, pathological reflex, and level of consciousness. However there were no significant correlations between abnormality of EEG findings and neuroimaging studies (CT and MRI)- related factors. 2) Laterality of EEG findings had significant relationships with abnormality, laterality, and focality of CT findings, and also with abnormality of MRI findings. But there were no significant correlations between laterality of EEG findings and clinical variables, and neurological examination-related factors. 3) Anterior-posterior distribution of EEG findings was significantly related with medication use. 4) Focality of EEG findings had significant relationships with sex, sensory dysfunction sign, and cerebellar dysfunction sign. But there were no significant correlations between focality of EEG findings and neuroimaging studies(CT and MRI) related factors. 5) Abnormal EEG pattern had significant correlations with various factors, such as age, chief complaints, duration from onset of symptom to taking MRI, seizure attack, abnormality and nature of lesion in CT findings, cortical atrophy in MRI findings, motor dysfunction sign, sensory dysfunction sign, and pathological reflex. 6) With abnormality on sleep activation, age, age of onset, seizure attack, ventricular enlargement in CT findings, and abnormality of MRI findings were significantly correlated. 7) With abnormality on hyperventilation activation, duration of illness and laterality of MRI findings were significantly correlated. Above results may suggest that abnormality of EEG findings is more closely related with functional change of the brain than structural changes of the brain and laterality of EEG findings is vice versa. And also that medication use has an influence on anterior versus posterior distribution of EEG findings and focality of EEG findings is not related with structural changes of the brain. Activation with sleep may be effective to show age differences and provocation of seizure activity and hyperventilation may be effective to detect the abnormal EEG findings by cerebrovascular insufficiency.