• The Journal of the Korea Contents Association
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• v.14 no.11
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• pp.893-904
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• 2014

This study is designed to analyze the status of R&D investment and managerial performance related to the domestic manufacturing. To accomplish the purpose of the study, We have regression analyzed 6,054 companies based on the data of 'Business Activity Survey' disclosed by Statistics Korea. Result of the study are as follows. First, electronics, IT, and auto industry account for 25.6% of the country's manufacturing companies and take up 75.8% of the total R&D funding for the manufacturing industry. Second, R&D funding exercises positive influence on sales and the number of registered patents, which last exerts positive influence on sales.

• Knowledge Management Research
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• v.19 no.3
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• pp.189-223
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• 2018

This paper examined the effect of innovation networks comprising research and development (R&D) collaboration on innovation performance of Korean pharmaceutical firms. As co-assigned patents and co-affiliated publications are common technical outcomes of successful R&D collaboration in the pharmaceutical industry, social network analysis technique was applied for analyzing innovation networks through patent and publication data. Results of Social network analysis indicated that a small set of highly innovative firms in the Korean pharmaceutical industry were actively involved in patenting and publishing. And the analysis of structural equation model found the followings: (1) R&D intensity significantly affected patenting, publication and new drug development, (2) the activity of patenting and publishing was positively related with the innovation performance measured by new drug development, and (3) R&D collaboration in terms of degree centrality of co-patent network played significant moderating roles on the relationships among R&D intensity, patenting, and new drug development. These findings are expected to be helpful to researchers as well as policy-makers to devise innovation-promoting policies in the Korean pharmaceutical industry. Discussions and limitations of the study are provided in the last part.

• Preventive Nutrition and Food Science
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• v.7 no.4
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• pp.386-396
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• 2002

This study screened 76 Korean traditional patent medicines and 58 medicinal herbs for antimicrobial activity against pathogenic bacteria. Among the prescriptions methanol and hot water extracts of Samsoum, Chujunghwang-yont'ang, and Sashinhwan showed antimicrobial activities against E. coli and Chujunghwang-yont'ang showed the strongest antimicrobial activity. Among the medicinal herbs, hot water and methanol extracts of Terminalia chebula, Caesalpinia sappan, and Coptis chinensis showed the strongest antimicrobial activities against Escherichia coli O157, Staphylococcus aureus, Shigella flexnery, Shigella sonnei and Salmonella typhimurium. An interesting characteristic of the traditional medicines such as Samsoum, Chujunghwang-yont'ang, and Sashinhwan was that both methanol and hot water extracts were active. Chujunghwang-yont'ang exhibited the strongest antimicrobial activities against the microorganisms tested. Water and methanol extracts of Terminalia chebula, Caesalpinia sappan, and Coptis chinensis showed the strong of inhibitory effects on the growth of all microorganisms tested.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.1
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• pp.101-113
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• 2015

Application of herbal medicines as natural preservatives has been increased because of its low toxicity or side effect, compared to artificial preservatives. In this study, papers and patents researching anti-microbial activity of herbal medicine were collected and analyzed by the year of publishment, species of bacteria, fungi, or yeasts, and herbal medicines used. After early 2000's, the number of paper publishment has been decreased, while that of patent registration has been increased up to early 2010's. Most studied species were Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa, as gram-positive or gram-negative bacteria, and Candida albicans and Aspergillus niger as fungi. The bark of Cinnamomum cassia (L.) J. Presl was most frequently studies herbal medicine, followed by the roots of Scutellaria baicalensis Georgi and Sophora flavescens Ait. This study demonstrates that herbal medicines can be used as natural preservatives against diverse species of bacteria, fungi, or yeasts with their wide-ranged anti-microbial activities.

• YAKHAK HOEJI
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• v.37 no.6
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• pp.581-590
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• 1993

In a preliminary screening of the plant extracts for the antigastritic action in rats, the extract of Aralia elata(Araliaceae) showed positive activity in HCI plus ethanol induced gastric lesion. Systematic fractions with hexane, chloroform, ethyl acetate and butanol resulted in the most patent activity with the butanol fraction: This butanol fraction at the oral dose of 200 mg/kg exhibited significant inhibition of absolute alcohol induced gastric lesion which was more potent than 100 mg/kg of cimetidine and had significant stimulation of mucus secretion. The butanol fraction showed significant decreases in the ulcer indices of Shay ulcers and inhibition of gastric juice secretion with acid output in pylorus-ligated stomachs of rats. It also suppressed the acetic acid induced gastric ulcer. These results might suggest that the butanol fraction had inhibitory action in gastric lesion and ulceration through inhibition of gastric acid secretion and stimulation of mucin secretion in the stomachs of rats.

• Journal of Korea Technology Innovation Society
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• v.19 no.3
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• pp.658-685
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• 2016

In technology economic theory, technology innovation through R&D is regarded as a core element of economic growth. This research analyzes how R&D input factor (R&D as a percentage of GDP, total number of researchers, the proportion of science and engineering degree) affects GDP, economic outcome variable, through mediating variable (S&T papers, patent registration). The most effective variable among R&D activity variables is following order: the number of S&T papers (0.967), the total number of researchers (0.373), the proportion of R&D expenditure (0.191), the number of patent registration (0.049), the proportion of science and engineering degree (0.007). It is that the proportion R&D expenditure and the total number of researchers shows greater indirect impact through S&T papers and patent than the direct impact on GDP. This implies the importance of high-quality human resources training and the necessity of maintaining the scale of R&D fund or the importance on GDP. Moreover, S&T papers turns out to have the greatest effect on GDP and implies new outcome and value by sharing and expanding new knowledge and technology created by R&D

• Journal of Digital Convergence
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• v.15 no.8
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• pp.511-516
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• 2017

The study conducted a systematic analysis through systematic literature to explore trends in physical activities and trends in the elderly and smart health care sector. Based on the research data collected from 2006 to 2017, the research paper was selected as an analysis data base and collected data from the patented patent data registered to the Patent Office. Based on the combination of the aged, physical activities, IT, IoT, and healthcare, the research identified the research trends and subjects through the analysis and analysis of subjects based on a total of 102 academic journals and 79 patents. First of all, the academic research published a surge in 2010 research in 2006, and it has emerged as an area of continuous interest in academia until 2017. Meanwhile, patents for patents soared in 2012, according to the company's patent. Second, research shows that studies are being conducted in five areas of research. Service design, monitoring systems, systems, policies, and other studies. In the case of patents, three types of patents were classified as patents, devices and information related to information. Subsequent studies will be deemed necessary to verify the effectiveness of the smart health care technology to enhance the health of the elderly.

• The Journal of Engineering Geology
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• v.20 no.3
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• pp.257-269
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• 2010

We analyzed patent trends regarding stabilization technology for steep slope hazards, focusing on patents applied for and registered in Korea, the USA, Japan, and Europe. The technology was classified into four groups at the second classification step: prediction techniques, instrumentation techniques, countermeasure/reinforcement/mitigation techniques, and laboratory tests. A total of 2,134 patents were selected for the final effective analysis. As a result of portfolio analysis using the correlation between the number of patents and the applicant for each patent, the Korean and USA situations were classified as belonging to the developing period, and the Japanese and European situations were classified as belonging to the ebbing period. In particular, patent activity in Korea has been enlivened by government-led research. As a result of technology analysis at the second classification step, prediction techniques arising from Japan are evaluated as a competitive power technique, and laboratory tests arising from the USA are evaluated as a competitive power technique. However, prediction techniques and laboratory tests arising from Korea are evaluated as a blank technique. According to the prediction results regarding future research and developments, a new finite element analysis method and a numerical model should be established as part of prediction techniques, as well as sensors, and hazard prediction should be developed by integrating information and equipment using IT technology as part of instrumentation techniques. In addition, improvements to existing structures for erosion control and the development of new slope-reinforcement methods are required as part of countermeasure/reinforcement/mitigation techniques, and new laboratory apparatus and methods with an optimizing structure should be developed as part of laboratory tests.

• Journal of the Economic Geographical Society of Korea
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• v.9 no.3
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• pp.318-340
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• 2006

In the last decade, there has been a widespread interest in knowledge production activities as a new engine of endogeneous growth. In the knowledge-based economy, there has been a growing importance of the patent as the index of knowledge production. Much literature suggests that knowledge production activities tend to be spatially concentrated and formed the clusters in the advanced economies. The purpose of this paper is to analyze spatial-temporal patterns of knowledge production activities in Korea based on a data set of patents from 1981-2000. This paper uses spatial statistical methods and GIS to explore the spatial dimensions of knowledge production activities in Korea. Through this research, it was found that knowledge production activities were unevenly distributed. The knowledge production activity measured by patent counts is highly concentrated in a limited number of cities. The top 10 cities accounted for 68.5% of the total number of patents in the period of 1981-2000, suggesting the existence of a strong concentration of knowledge production activities in Korea. The locations of knowledge production activities by themselves represented a strong spatial autocorrelation. The concentration of knowledge production activities in Korea is spatially correlated to the concentration of adjacent neighboring cities. The location of knowledge production activities is not free from a spatial context and spillover of knowledge production activities are heavily bounded within geographic limits, forming a spatial cluster. There appear some quite a large spatial cluster around the seoul metropolitan area.

• Journal of Korean society of Dental Hygiene
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• v.24 no.4
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• pp.301-309
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• 2024

Objectives: This study aimed to measure the awareness and needs for intellectual property (IP) education among university students majoring in health-related fields to inform the development of future IP education curricula. Methods: The study was conducted through an online survey from January 5 to 26, 2024, targeting students from the health-related departments (Department of Physical Therapy, Health Administration, Clinical Laboratory Science, and Dental Hygiene) at Dankook University located in Cheonan City, Chungcheongnam-do. Results: A total of 151 students participated in the survey. Among the respondents, 84.8% were women, and the largest groups of respondents were from the Health Administration and Dental Hygiene departments, each accounting for 32.5%. Only 13.9% of the respondents had taken courses related to IP, and 22.5% had related activity experience. The overall average importance score of IP education was 3.88 (±0.80), and the overall average need score was 3.78 (±0.80). An Importance-Performance Analysis (IPA) Matrix analysis revealed that 13 topics fell into the first quadrant (high importance, high need), one topic into the second quadrant (low importance, high need), 18 topics into the third quadrant (low importance, low need), and four topics into the fourth quadrant (high importance, low need). The educational topics identified as first quadrant include 'Securing patent rights', 'Requirements for patent registration', 'Effects and contents of patent rights', 'Patent infringement and remedies', and 'Effects and contents of copyrights'. Conclusions: Future IP education programs should develop innovative educational content and methods that consider both the importance and needs to increase students' interest and engagement.