• Journal of Periodontal and Implant Science
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• v.36 no.3
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• pp.757-765
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• 2006

Human periodontal ligament fibroblasts (hPDLF) are very important for curing the periodontal tissue because they can be differentiated into various cells. A tissue engineering approach using a cell-scaffold is essential for comprehending today's periodontal tissue regeneration procedure. This study examined the possibility of using an acellular dermal matrix as a scaffold for human periodontalligament fibroblast (hPDLF). The hPDLF was isolated from the middle third of the root of periodontally healthy teeth extracted for orthodontic reasons. The cells were cultured in a medium containing Dulbecco's modified Eagle medium supplemented with 10% fetal bovine serum at $37^{\circ}C$ in humidified air with 5% $CO_2$. The acellular dermal matrix(ADM) was provided by the US tissue banks(USA). Second passage cells were used in this study. The hPDLF cells were cultured with the acellular dermal matrix for 2 days, and the dermal matrix cultured by the hPDLF was transferred to a new petri dish and used as the experimental group. The control group was cultured without the acellular dermal matrix, The control and experimental cells were cultured for six weeks. The hPDLF cultured on the acellular dermal matrix was observed by Transmission Electron microscopy (TEM). Electron micrography shows that the hPDLF was proliferated on the acellular dermal matrix. This study suggests that the acellular dermal matrix can be used as a scaffold for hPDLF.

• Asian Oncology Nursing
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• v.10 no.2
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• pp.218-230
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• 2010

Purpose: This study was conducted to develop the telecommunication guideline that was possible to make the immediate, logical decisions and to evaluate the possibility of the use by verifying it from the specialists' group. Methods: Telecommunication guideline was designed with selected six symptoms which were pain, dyspnea, nausea/vomiting, diarrhea, fever, and cough based on the results of literature. Results: This study showed that the patients understood well about the contents of the questions, examination, and education. Also, 85% of them fulfilled the guidelines of the adjustment and more of them were satisfied with the results shown to all of them compared to the previous telecommunication. And 95% of them replied that the information from the telecommunication was more useful than any other information sources related to the information of cancer and self management that were used previously. Conclusion: The telecommunication was considered to complement the weakness during the time the cancer patients spent at home after the treatments. Also, it was expected to be a role as an immediate and comprehensive method of decision making and a passage for information supply which was considered the specialty of individual patient related to an inquiry of the self management.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.12
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• pp.5303-5307
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• 2016

Objective: Brain tumors cause great mortality and morbidity worldwide, and success rates with surgical treatment remain very low. Several recent studies have focused on introduction of novel effective medical therapeutic approaches. Genistein is a member of the isoflavonoid family which has proved to exert anticancer effects. Here we assessed the effects of genistein on the expression of MMP-2 and VEGF in low and high grade gliomas in vitro. Materials and Methods: High and low grade glioma tumor tissue samples were obtained from a total of 16 patients, washed with PBS, cut into small pieces, digested with collagenase type I and cultured in DMEM containing 10% FBS. When cells reached passage 3, they were exposed to genistein and MMP-2 and VEGF gene transcripts were determined by quantitative real time PCR (qRT-PCR). Results: Expression of MMP-2 demonstrated 580-fold reduction in expression in low grade glioma cells post treatment with genistein compared to untreated cells (P value= 0.05). In cells derived from high grade lesions, expression of MMP-2 was 2-fold lower than in controls (P value> 0.05). Genistein caused a 4.7-fold reduction in VEGF transcript in high grade glioma cells (P value> 0.05) but no effects were evident in low grade glioma cells. Conclusion. Based on the data of the present study, low grade glioma cells appear much more sensitive to genistein and this isoflavone might offer an appropriate therapeutic intervention in these patients. Further investigation of this possibility is clearly warranted.

• Journal of the Korea institute for structural maintenance and inspection
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• v.13 no.6 s.58
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• pp.192-203
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• 2009

In the new Seoul-Busan high speed railroad construction specially in area of city center passage the roadbed establishment is recommended the staibility for the existing subway tunnel segments of Busan subway 1st and 2nd lines regarding the appearance condition, a quality condition and the durability of the objective facility, and it evaluates the numerical analysis using MIDAS/GTS which leads the stability of the objective facility and investigatesd tunnels. Fundamental issues in tunneling under high groundwater table are discussed and the effect of groundwater on tunnel excavation was examined using a 3D stress-pore pressure coupled Finite-Element Method. Based on the results the interaction mechanism between the tunnelling and groundwater is identified. In the both of 1st and 2nd Line the maximum sinkage, unequal sinkage and the lining stress from numerical analysis are within permission and the damage degree is appearing to be disregarded. But it enforces necessary Pre-grouting in order to minimize an actual tunnel face conduct and when the tunnel is excavated it is also necessary to minimize the outflow possibility.

• Journal of the Korea Fashion and Costume Design Association
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• v.25 no.1
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• pp.153-168
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• 2023

Non-representation creates difference and change that can be used as a creative design method that satisfies contradictory requirements for similarity and differentiation. This study drew upon the characteristics of the concept of non-representation expressed in contemporary art and architecture, in which Gilles Deleuze's philosophical thinking was reflected, and analyzed the non-representation depicted in contemporary fashion. The non-representation expressed in contemporary art and architecture is as follows. Non-representation of delaying becoming focuses on reverting to preexisting objects and redefining traditional meaning, thereby delaying the representation of latent meaning. Non-representation of non-becoming removes existing values and typical forms and expresses amorphousness. Non-representation of becoming by repetition or reiteration realizes the difference caused by the passage of time by repeating or overlapping shapes. Non-representation of becoming expresses the transformation of space by flowing through time rather than by actual movement. Non-representation in contemporary fashion shows the following expression characteristics. First, the non-representation of deferring becoming deconstructs the traditional values and forms of clothing and expresses designs by displacement or juxtaposition. Second, the non-representation of non-becoming is expressed concepts unrelated to the body and focus upon amorphous objects that do not become concretized forms. Third, generative non-representation by repetition and overlap expresses the possibility of change by overlapping clothing items or details expressed by repeating segmented objects. Fourth, generative non-representation by movement reproduces the meaning of space and time by moving the shape of the clothing or visually changing the surface of the material of clothing. As a result of the study, the non-representation shown in contemporary fashion aims for versatility to conform to social changes. This study provides new insight into the fashion design method by increasing the understanding of the cocnept of non-representation and showing its potential.

• Journal of Korean Society of Environmental Engineers
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• v.36 no.8
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• pp.588-595
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• 2014

Carbon nanomaterials such as fullerene, carbon nanotube and graphene are representative nanomaterials and widely used in various fields. Carbon nanomaterials can be exposed to environments during their production, usage and disposal, spreading to different systems and posing a great threat to various ecological receptors. Researches are conducted in order to determine the possibility of groundwater exposure to carbon nanomaterials due to their release and passage through soils. If soils can play a significant role in limiting the transport of carbon nanomaterials, the possibility of groundwater exposure to carbon nanomaterials can be reduced greatly. This review paper presented the research works performed for the mobility of carbon nanomaterials in soil media. Also, the paper provided the factors affecting the transport of carbon nanomaterials in soil media along with the DLVO theory/colloid filtration theory/transport model, which are used to describe the transport of carbon nanomaterials in soil media. Recently, production of carbon nanomaterials and their commercial and environmental applications increase rapidly in Korea. Therefore, researches regarding the fate and transport of domestic carbon nanomaterials in soil environments should be performed in various environmental conditions.

• The Journal of the Korea Contents Association
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• v.11 no.9
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• pp.506-514
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• 2011

The purpose of this study is to look into whether there is a possibility to develop the image of the local community in conjunction with green tourism, thus to explore the concrete ways to vitalize local community with diversified green tourism programs. In the pursuit of relating the research of community image-building with comprehensive local characteristics, this study selected the case of Jung Bang I village near Daejeon and analyzed the case through both written materials and on-site investigation. As a result of analysis, first, it was found that community image-building contributed positive effects in terms of the commercialization of the local community and its revitalization. Second, it was observed that community image-building led to form a "green route" that played a role as a passage to link townspeople to the country. It was also verified that those country villages that succeeded in image-building provided the places where people could experience the country and arts, which showed the potential of their roles as educational opportunities. In conclusion, this study will be able to suggest the direction to where the green tourism and image-building projects of the small communities near towns should go, and also provide a substantial guideline to related people regarding how to operate and maintain the local community.

• Fire Science and Engineering
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• v.31 no.4
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• pp.95-102
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• 2017

The fires in the traditional markets often occur recently with the most of them expanded into great fires so that the damage is very serious. The status of traditional markets handling the distribution for ordinary people is greatly shrunk with the aggressive marketing of the local large companies and the foreign large distribution companies after the overall opening of the local distribution market. Most of the traditional markets have the history and tradition from decades to centuries and have grown steadily with the joys and sorrows of ordinary people and the development of the local economy. The fire developing to the large fire has the characteristics of the problem that the fire possibility is high since all products can be flammable due to the deterioration of facilities, the arbitrary modification of equipment, and the crowding of the goods for sale. Furthermore, most of the stores are petty with their small sizes so that the passage is narrow affecting the passage of pedestrians. Accordingly, the traditional markets are vulnerable to fire due to the initial unplanned structural problem so that the large scale fire damage occurs. The study is concerned with systematically classifying and analyzing the result by applying the TRIZ tool to the fire risk factors to extract the fundamental problem with the fire of the traditional market and make the active response. The study was done for preventing the fire on the basis of it and the expansion to the large fire in case of fire to prepare the specific measure to minimize the fire damage. On the basis of the fire expansion risk factor of the derived traditional market, the study presented the passive measures such as the improvement of the fire resisting capacity, the fire safety island, etc. and the active and institutional measures such as the obligation of the fire breaking news facilities, the application of the extra-high pressure pump system, the divided use of the electric line, etc.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.20 no.2
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• pp.203-211
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• 2008

More recently, the massive marine bridges in a ship passage have been constructed on the sea. Therefore, the ship impact protection for the bridge-piers are installed to consider the possibility of vessel collision danger. Due to the ship impact protection, the pier-scour characteristics are changed in comparison with the condition without the ship impact protection (SIP). In this study, the physical modeling for the Incheon Sea-Crossing Bridge was performed to analyze the pier-scour characteristics with respect to the vessel collision protection. The rigid and movable bed tests were conducted to evaluate the flow pattern, scour depth, and scourhole with and without the ship impact protection. The experimental results for the maximum scour depth is increased 0.24 m in W1 pier at the same location and 2.4 m in W2+3+4 piers due to the SIP installation. Especially, the maximum scour depth in W2+3+4 piers was occurred around the SIP.

• Journal of the Korean Association of Geographic Information Studies
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• v.20 no.3
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• pp.67-79
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• 2017

Increasing transportation dependence on the metro system has lead to the convenience of passengers becoming as important as the transportation capacity. In this study, a pedestrian simulator has been developed that can quantitatively assess the pedestrian environment in terms of attributes such as speed and distance. The simulator consists of modules designed for 3D indoor map authoring and algorithmic pedestrian modeling. Module functions for 3D indoor map authoring include 3D spatial modeling, network generation, and evaluation of obtained results. The pedestrian modeling algorithm executes functions such as conducting a path search, allocation of users, and evaluation of level of service (LOS). The primary objective behind developing the said functions is to apply and analyze various scenarios repeatedly, such as before and after the improvement of the pedestrian environment, and to integrate the spatial information database with the dynamic information database. Furthermore, to demonstrate the practical applicability of the proposed simulator in the future, a test-bed was constructed for a currently operational metro station and the quantitative index of the proposed improvement effect was calculated by analyzing the walking speed of pedestrians before and after the improvement of the passage. The possibility of database extension for further analysis has also been discussed in this study.