• Journal of fish pathology
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• v.25 no.1
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• pp.1-10
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• 2012

It has been reported that various anti-oxidant substances stimulate non-specific immune responses in fishes. In this study it was examined whether N-acetylcysteine (NAC), an anti-oxidant glutathione (GSH) precursor, can modulate non-specific immune parameters in 8 different fishes. NAC was intraperitoneally administered at 10 mg/kg to catfish (Silurus asotus), loach (Misgurnus mizolepis), common carp (Cyprinus carpio), crucian carp (Carassius carassius), eel (Anguilla japonica), snakehead (Channa argus), tilapia (Oreochromis niloticus) and mullet (Mugil cephalus). Forty-eight hours later, chemiluminescence (CL) response of head-kidney leukocytes and serum lysozyme activity were assessed. In all fishes except crusian carp and loach, CL responses were amplified by NAC. Lysozyme activity was increased by NAC in all fish species but not in tilapia. This result suggests that NAC stimulates non-specific immune responses in various species, and that such effects may have beneficial significance in aquaculture for practical utilization.

• Journal of Environmental Policy
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• v.11 no.4
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• pp.85-105
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• 2012

In this paper, the energy efficiency of wastewater utilities was evaluated to explore ways to save energy via operational measures. The correlation of each wastewater characteristic parameter to energy was assessed to find a set of parameters that explained most of the variations in energy use among utilities. The results show that increases in inflow, influent COD concentration, and ratio of advanced treatment generally increased the energy use. On the other hand, increases in load factor (influentaverage flow/design flow) reduced the energy use. In the regression analysis, the energy efficiency was highest in the A2O advanced process. On the other hand, the membrane process (among the advanced processes) and the contacted aeration process (among the secondary processes) require more efforts in saving energy. However, the data base system related to energy use must be supplemented in order for more accurate analysis of energy consumption in wastewater treatment facilities. In particular, i) electricity consumption of relay pumps and, ii) energy usage per unit process, iii) pump power usage to discharge treated wastewater in a long distance, if necessary, and iv) alternative energy production and utilization status must be recorded. By utilizing the results of the analysis conducted in this study, it is possible to quantify a level of energy savings needed and establish customized energy saving measures to achieve a certain target level for benchmarking a successful case of wastewater utilities.

• Journal of the Korean earth science society
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• v.33 no.1
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• pp.39-48
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• 2012

In this study, a statistical estimation of probable precipitation and an analysis of its return period in Busan were performed using long-term precipitation data (1973-2007) collected from the Busan Regional Meteorological Administration. These analyses were based on the method of probability weighted moments for parameter estimation, the goodness-of-fit test of chi-square ($x^2$) and the probability plot correlation coefficient (PPCC), and the generalized logistics (GLO) for optimum probability distribution. Moreover, the spatial distributions with the determination of probable precipitation were also investigated using precipitation data observed at 15 Automatic Weather Stations (AWS) in the target area. The return periods for the probable precipitation of 245.2 and 280.6 mm/6 hr with GLO distributions in Busan were estimated to be about 100 and 200 years, respectively. In addition, the high probable precipitation for 1-, 3-, 6-, and 12-hour durations was mostly distributed around Dongrae-gu site, all coastal sites in Busan, Busanjin and Yangsan sites, and the southeastern coastal and Ungsang sites, respectively.

• The Journal of Advanced Prosthodontics
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• v.10 no.3
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• pp.218-226
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• 2018

PURPOSE. The aim of this study was to define a color space of non-vital teeth and to compare it with the color space of matched vital teeth, recorded in the same patients. MATERIALS AND METHODS. In a group of 218 patients, with the age range from 17 to 70, the middle third of the buccal surface of 359 devitalized teeth was measured using a clinical spectrophotometer (Vita Easyshade Advance). Lightness ($L^*$), chromatic parameters ($a^*$, $b^*$), chroma ($C^*$), hue angle (h) and the closest Vita shade in Classical and 3D Master codifications were recorded. For each patient, the same data were recorded in a vital reference tooth. The measurements were performed by the same operator with the same spectrophotometer, using a standardized protocol for color evaluation. RESULTS. The color coordinates of non-vital teeth varied as follows: lightness $L^*$: 52.83-92.93, $C^*$: 8.23-58.90, h: 51.20-101.53, $a^*$: -2.53-24.80, $b^*$: 8.10-53.43. For the reference vital teeth, the ranges of color parameters were: $L^*$: 60.90-97.16, $C^*$: 8.43-39.23, h: 75.30-101.13, $a^*$: -2.36-9.60, $b^*$: 8.36-39.23. The color differences between vital and non-vital teeth depended on tooth group, but not on patient age. CONCLUSION. Non-vital teeth had a wider color space than vital ones. Non-vital teeth were darker (decreased lightness), more saturated (increased chroma), and with an increased range of the hue interval. An increased tendency towards positive values on the $a^*$ and $b^*$ axes suggested redder and yellower non-vital teeth compared to vital ones.

• Journal of the Korean Society of Food Science and Nutrition
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• v.41 no.9
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• pp.1310-1314
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• 2012

Gastrointestinal digestibility of new proteins inserted in the food supply is a significant parameter for assessing the safety of GM foods based on the assumption that digestive stability is undesirable. In this study, we performed in vitro digestion of CP4EPSPS, a new protein, expressed in genetically modified (GM) soybean in order to evaluate its digestibility in three different ratios of simulated gastric fluid with preheating. Ratios of GM soybean to simulated gastric fluid were 2:2, 2.5:1.5, and 1.5:2 and preheating was conducted at $100^{\circ}C$ for 5 min. Electrophoresis and Western blotting were used to confirm changes in soybean protein patterns and CP4EPSPS gene expression after in vitro digestion. At ratios in which the amount of gastric fluid was equal to (2:2) or relatively higher than that of soybean (1.5:2), no CP4EPSPS (47.4 kDa) protein was detected after 15 seconds of simulated gastric fluid incubation, the earliest time interval evaluated. However, when the ratio of GM soybean to gastric fluid was 2.5:1.5, CP4EPSPS was detected in 5 min and gradually decreased according to time. After preheating, no CP4EPSPS protein was detected after 15 seconds under all conditions. From these results, we concluded that the digestibility of CP4EPSPS in simulated gastric fluid increased upon preheating. Accordingly, we suggest that it is important to account for the ratio of gastric fluid to GM food in in vitro digestibility assessment models of GM food.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.9
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• pp.1462-1466
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• 2014

In this study, an attempt was made to produce oat protein concentrates from defatted oat groat by alkali extraction. Independent variables formulated by D-optimal design were NaOH concentration (X1, 0.005~0.06 N) for extraction and precipitation pH (X2, pH 4.0~6.0), and the dependent variable was extraction yield (Y1, %). Experimental results were analyzed by response surface methodology to determine optimized extraction conditions. Extraction yield increased both with an increase in NaOH concentration of the extraction solution and when approaching a precipitation pH of 4.9, and NaOH concentrations were a major influencing parameter. Solubility of oat protein concentrates showed a minimum value (i.e., 0.1%) at pH 5 and increased substantially at pH values in the range of ${\leq}$ pH 3 or ${\geq}$ pH 7, reaching a maximum value at pH 11 (i.e., 76%). Regression equation coincided well with the results of the experiment. Optimized extraction conditions to maximize extraction yield were 0.06 N NaOH (X1) for extraction and pH 4.7 (X2) for precipitation.

• Journal of Gastric Cancer
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• v.3 no.1
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• pp.38-43
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• 2003

Purpose: Caspase 2, a member of the family of ICE-like proteases, is activated by the Fas pathway and induces apoptosis by triggering the caspase cascade. The purpose of this study was to determine whether the expression pattern of caspase 2 might be associated with gastric cancer development and if so, to determine to which pathologic parameter it is linked. Materials and Methods: For the construction of the gastric cancer tissue microarray, 78 paraffin-embedded tissues containing gastric cancer areas were cored 3 times and transferred to the recipient master block. The expression pattern of caspase 2 was examined on tissue microarray slides by using immunohistochemistry and was compared with pathologic parameters, including histologic type, depth of invasion, lymph node metastasis, and peritoneal dissemination. Results: Caspase 2 was expressed on superficial and foveolar epithelial cells and lymphocytes in the gastric mucosa, mainly in cytoplasm. We found loss of caspase 2 expression in 41 ($52.6\%$) of the 78 gastric cancer tissues. Statistically, histologic type and other pathologic parameters were not related with loss of caspase 2 expression Conclusion: Our findings provide enough evidence that loss of caspase 2 expression may contribute to the development of Korean gastric cancer and that it might be one of the possible escape mechanisms from apoptosis in gastric cancer.

• Korean Journal of Construction Engineering and Management
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• v.16 no.5
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• pp.77-85
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• 2015

The Hedonic Pricing model is the predominant approach used today to model the effect of relevant factors on real estate prices. These factors include intrinsic elements of a property such as floor areas, number of rooms, and parking spaces. Also, The model also accounts for the impact of amenities or undesirable facilities of a property's value. In the latter case, euclidean distances are typically used as the parameter to represent the proximity and its impact on prices. However, in situations where multiple facilities exist, multi-colinearity may exist between these parameters, which can result in multi-regression models with erroneous coefficients. This research uses Variance Inflation Factors(VIF) and Ridge Regression to identify these errors and thus create more accurate and stable models. The techniques were applied to apartments in Guro-gu of Seoul, whose prices are impacted by subway stations as well as a public prison, a railway terminal and a digital complex. The VIF identified colinearity between variables representing the terminal and the digital complex as well as the latitudinal coordinates. The ridge regression showed the need to remove two of these variables. The case study demonstrated that the application of these techniques were critical in developing accurate and robust Hedonic Pricing models.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.37 no.2
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• pp.45-53
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• 2000

In wireless environment, due to the limited capacity of radio channels it is not easy to guarantee QoS provisioning to mobile users. Therefore, one of the key problems to support broadband multimedia multi-services in wireless ATM networks is to study an effective call admission control(CAC). The purpose of this paper is to propose a distributed CAC scheme that guarantees multi QoS and multi-class service. Control parameters of the proposed scheme are QoS threshold and channel overload probability. With these parameter control, we show that the scheme can guarantee the requested QoS to both new and handover calls. In the scheme, channels are allocated dynamically, and QoS measurements are made in a distributed manner. We show that by providing variable data rate to calls it can effectively prohibit the QoS degradation even if there are severe fluctuations of network traffic. We compare the proposed CAC scheme to the well-known schemes such as guard band call admission control scheme. Through numerical examples and simulations, the proposed scheme is shown to improve the performance by lowering the probability of handover call dropping

• Journal of the Korean Geotechnical Society
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• v.18 no.2
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• pp.51-64
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• 2002

Observational results of ground movement during the construction were very different from those predicted during the analysis of design step because of the uncertainty of the numerical analysis modelling, the soil parameter, and the condition of a construction field, etc., however accurately numerical analysis method was applied for prediction of ground movement per the excavation step. Therefore, the management system through the construction field measurement should be achieved for grasping the situation during the excavation. Until now, the measurement system restricted by 'Absolute Value Management system'analyzing only the stability of present step has been executed. So, it was difficult to expect the prediction of ground movement fur the next excavation step. In this situation, this study developed 'The Management system TOMAS-EXCAV'consisted of 'Absolute value management system'analyzing the stability of present step and 'Prediction management system'expecting the ground movement of next excavation step and analyzing the stability of next excavation step by 'Back Analysis'. TOMAS-EXCAV could be applied to all the uncertainty of earth retaining structures analysis by connecting 'Forward analysis program'and 'Back analysis program'and optimizing the main design variables using SQP-MMFD optimization method through measurement results. The applicability of TOMAS-EXCAV was confirmed by back analysis selecting two earth retains construction fields.