• Title/Summary/Keyword: PSG

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Nitric Oxide Production Ability and its Formation Mechanisms in Macrophage TIB 71 Cell Line by Polysaccharide Extracted from Ganoderma lucidum (영지버섯 다당체의 Nitric Oxide 생성능 및 생성기전 연구)

  • 김성환
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.2
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    • pp.333-337
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    • 1998
  • This study was carried out to get infomation on the nitric oxide production ability and its formation mechanisms of polysaccharides extracted from Ganoderma lucidum(PSG) by using murine macrophage cell line. The cultured mycelial cells of Ganoderma lucidum were extracted by alkali, and than neutralized by acid. The extract were passed through the column of DEAE cellulose for more purification. The neutral fraction was concentrated and precipitated with 95% ethanol. The precipitate was lyophilized and PSG was obtained. The immunomodulating effects of PSG on macrophage were performed by using murine macrophage cell line ATCC TIB 71 cells with PSG 0.5mg. PSG alone could not induce the production of nitrite, but it had a significant potential effect on nitrite secretion when the cells were primed and triggered with BCG and Interferon(IFN)-${\gamma}$. Also it was prominent by using calcium channel blocker(verapamil) and adenylate cyclase activator(forskolin).

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Studies on the Polysaccharide Extracted from Ganoderma Incidum (영지버섯에서 분리한 항암성 다당체에 관한 연구)

  • 김성환;김을상;김영식
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.1
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    • pp.147-153
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    • 1995
  • The cultured mycelial cells of Ganoderma lucidum was extracted by alkali, and then neutralized by acid. The extract was passed through the column of DEAE cellulose for more purification. The neutral fraction was concentrated and precipitated with 95% ethanol. The precipitate was lyophilized and then PSG(polysaccharides) was obtained. PSG was composed of 82.2% polysaccharide, 0.7% protein and 17.1% uronic acid. Sugar conjugates of its hydrolysates were produced using with fluorescent compound(7-amino-1,3-naphthalene disulfonic aicd : 7-AGA), and then fluorescent labeled sugar conjugates were separated by reverse phase high perfomance liquid chromatography. Hydrolysates of PSG were composed of sixteen amino acids and 95.7% glucose, 2.7% xylose, 1.6% fucose and tract amount of galactose and mannose. The immunomodulating effects of PSG on macrophage were perfomed using murine macrophage cell line ATCC TIB 71 cells. PSG augumented the phagocytic activity of TIB 71 cells against fluorescent latex beads.

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Microfabrication of Photosensitive Glass Using Metal Patterning and Blank Exposure (금속 패터닝과 Blank노광을 이용한 감광성 유리의 미세가공)

  • Jo, Jae-Seung;Kang, Hyung-Bum;Yoon, Hye-Jin;Kim, Hyo-Jin;Lim, Hyun-Woo;Cho, Si-Hyeong;Lim, Sil-Mook
    • Journal of the Korean institute of surface engineering
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    • v.46 no.3
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    • pp.99-104
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    • 2013
  • The simple and cost-effective microfabrication method of photosensitive glass (PSG) using metal patterning and blank exposure was proposed. Conventional photolithography for micromachining of PSG needs a costly quartz mask which has high transmittance as an optical property. However, in this study the process was improved through the combination of micro-patterned Ti thin film and blank UV exposure without quartz mask. The effect of UV exposure time as well as the DHF etching condition was investigated. UV exposure test was performed within the range from 3 min to 9 min. The color and etch result of PSG exposed for 5 min were the most clear and effective to etch more precisely, respectively. The etching results of PSG in diluted hydrofluoric acid (DHF) with a concentration of 5, 10, 15 vol% were compared. The effect on the side etch was insignificant while the etch rate was proportional as the concentration increased. 10 vol% DHF results not only high etch rate of 75 ${\mu}m/min$ also lower side etch value after PSG etching. This method facilitates the microfabrication of PSG with various patterns and high aspect ratio for applying to advanced applications.

Analysis of the Na Gettering in SiO2/PSG/SiO2/Al-1%Si and SiO2/TEOS/SiO2/Al-1%Si Multilevel Thin Films using SIMS (SIMS를 이용한 SiO2/PSG/SiO2/Al-1%Si 및 SiO2/TEOS/SiO2/Al-1%Si 적층 박막내의 Na 게터링 분석)

  • Kim, Jin Young
    • Journal of the Korean institute of surface engineering
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    • v.51 no.2
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    • pp.110-115
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    • 2018
  • The Na low temperature gettering in $SiO_2/PSG/SiO_2/Al-1%Si$ and $SiO_2/TEOS/SiO_2/Al-1%Si$ multilevel thin films was investigated using dynamic SIMS(secondary ion mass spectrometry) analysis. DC magnetron sputter, APCVD and PECVD techniques were utilized for the deposition of Al-1%Si thin films, $SiO_2/PSG/SiO_2$ and $SiO_2/TEOS/SiO_2$ passivations, respectively. Heat treatment was carried out at $300^{\circ}C$ for 5 h in air. SIMS depth profiling was used to determine the distribution of Na, Al, Si and other elements throughout the $SiO_2/PSG/SiO_2/Al-1%Si$ and $SiO_2/TEOS/SiO_2/Al-1%Si$ multilevel thin films. XPS was used to analyze chemical states of Si and O elements in $SiO_2$ passivation layers. Na peaks were observed throughout the $PSG/SiO_2$ and $TEOS/SiO_2$ passivation layers on the Al-1%Si thin films and especially at the interfaces. Na low temperature gettering in $SiO_2/PSG/SiO_2/Al-1%Si$ and $SiO_2/TEOS/SiO_2/Al-1%Si$ multilevel thin films is considered to be caused by a segregation type of gettering.

Optimal lay-up of hybrid composite beams, plates and shells using cellular genetic algorithm

  • Rajasekaran, S.;Nalinaa, K.;Greeshma, S.;Poornima, N.S.;Kumar, V. Vinoop
    • Structural Engineering and Mechanics
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    • v.16 no.5
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    • pp.557-580
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    • 2003
  • Laminated composite structures find wide range of applications in many branches of technology. They are much suited for weight sensitive structures (like aircraft) where thinner and lighter members made of advanced fiber reinforced composite materials are used. The orientations of fiber direction in layers and number of layers and the thickness of the layers as well as material of composites play a major role in determining the strength and stiffness. Thus the basic design problem is to determine the optimum stacking sequence in terms of laminate thickness, material and fiber orientation. In this paper, a new optimization technique called Cellular Automata (CA) has been combined with Genetic Algorithm (GA) to develop a different search and optimization algorithm, known as Cellular Genetic Algorithm (CGA), which considers the laminate thickness, angle of fiber orientation and the fiber material as discrete variables. This CGA has been successfully applied to obtain the optimal fiber orientation, thickness and material lay-up for multi-layered composite hybrid beams plates and shells subjected to static buckling and dynamic constraints.

Optimization of PSG Flowing and Metallization for Step Coverage Improvement (스텝 커버리지를 위한 PSG와 기첩처리 공정 조건의 개선)

  • 김도진;이종덕
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.19 no.6
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    • pp.91-95
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    • 1982
  • One significant problem which arises during the fabrication of LSI and/or VLSI is how to make a good step coverage for aluminum. One way developed in this study is to flow PSG containing 8.0 wt.% - 8.6 wt.% of phosphorus at 95$0^{\circ}C$ for 30 minutes in steam and to depo3it aluminum of 1 urn thickness at $250^{\circ}C$.

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Studies on Anti-Mcirobial and Anti-Cancer Functions of Polysaccharide Extracted from Ganoderma lucidum (영지버섯 다당체의 항미생물작용 및 항암작용에 관한 연구)

  • 김성환
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.27 no.6
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    • pp.1183-1188
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    • 1998
  • This study was carried out to elucidate the immunomodulating activity of protein bound polysac charide extracted from Ganoderma lucidum(PSG). Macrophage drived reactive radicals were known as an effector for antimicrobial and anticancer functions. The promising immune response molecule, reactive oxygen intermediates(ROIs), was determined in TIB 71 cells with PSG at various experimental conditions. Treatment with 0.5mg PSG significantly increased the production of ROIs, superoxide anion as well as hydrogen peroxide, from TIB 71 cells(p<0.001). Under the same concentration, con siderable results were obtained from 24 hour cultivation with 106 cells at 5% CO2 incubator. The cells were trigged with PMA(5.3 M) after primed BCG(100 M) or IFN (100U) alone could not induce the production of ROIs, but it had a significant potentiating effect on ROIs secretion when the cells were treated with PSG.

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Development & Characteristics of the Permanent Grout based on Colloidal Silica (실리카 콜로이드를 기재(基材)로 한 항구그라우트(PSG)의 개발과 공학적 특성)

  • Ryu, Dong-Sung;Jeong, Gyung-Hwan;Lee, Sng-Kook;Lee, Jun-Seok
    • Proceedings of the Korean Geotechical Society Conference
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    • 2004.03b
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    • pp.189-196
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    • 2004
  • In this study, the colloidal silica grouts (PSG) with novel chemical compositions for permanent reinforcement and water cut-off of the ground were prepared and their engineering charateristics were investigated. The optimum mixing recipes for both homogeneous solution grouts and heterogeneous suspension grouts were investigated and established through many repeated lab tests. The various physical properties(such as compressive strength, durability and syneresis) of the grout gels derived from the colloidal silica were investigated and compared with those of the well-known existing watergalss grouts. The all experimental results showed that the novel colloidal silica grouts(PSG) had greatly excellent performances as permanent grouts, especially in comparison with the existing watergalss grouts.

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Passivation Layer Structures with a Silicon Nitride film (질화실리콘막을 사용한 표면보호층 구조에 관한 연구)

  • 이종무
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.22 no.6
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    • pp.53-57
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    • 1985
  • Comparisons and analyses were made of the properties of double or triple passivation layer structures composed of APCVD SiOt or PSG and PECVD SiN films with various layer combinations and layer thicknesses. As a result of the analyses of the pro.peHics such as threshold-voltage shift, crack resistance, pinhole density, and moisture reslstancei a con-clusion was reached that the proper passivation layer structure is the double layer consisting of a 4,00$\AA$ or thicker PSG film and a 6,000$\AA$ SiN film.

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HYERS-ULAM STABILITY OF FRACTIONAL STOCHASTIC DIFFERENTIAL EQUATIONS WITH RANDOM IMPULSE

  • Dumitru Baleanu;Banupriya Kandasamy;Ramkumar Kasinathan;Ravikumar Kasinathan;Varshini Sandrasekaran
    • Communications of the Korean Mathematical Society
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    • v.38 no.3
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    • pp.967-982
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    • 2023
  • The goal of this study is to derive a class of random impulsive non-local fractional stochastic differential equations with finite delay that are of Caputo-type. Through certain constraints, the existence of the mild solution of the aforementioned system are acquired by Kransnoselskii's fixed point theorem. Furthermore through Ito isometry and Gronwall's inequality, the Hyers-Ulam stability of the reckoned system is evaluated using Lipschitz condition.