• Corrosion Science and Technology
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• 제17권1호
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• pp.20-29
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• 2018

Ti and its alloys show the excellent corrosion resistance to chloride environments, but they show less corrosion resistance in HCl, $H_2SO_4$, NaOH, $H_3PO_4$, and especially HF environments at high temperature and concentration. In this study, we used the commercially pure titanium and Ti-6Al-4V alloy, and evaluated the effect of the manufacturing process on the electrochemical properties. We used commercial products of rolled and forged materials, and made additive manufactured materials by DMT (Directed Metal Tooling) method. We annealed each specimen at $760^{\circ}C$ for one hour and then air cooled. We performed anodic polarization test, AC impedance measurement, and Mott-Schottky plot to evaluate the electrochemical properties. Despite of the difference of its microstructure of CP-Ti and Ti-6Al-4V alloys by the manufacturing process, the anodic polarization behavior was similar in 20% sulfuric acid. However, the addition of 0.1% hydrofluoric acid degraded the electrochemical properties. Among three kinds of the manufacturing process, the electrochemical properties of additive manufactured CP-Ti, and Ti-6Al-4V alloys were the lowest. It is noted that the test materials showed a Warburg impedance in HF acid environments.

• Journal of Microbiology and Biotechnology
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• 제25권4호
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• pp.496-502
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• 2015

Polyketide secondary metabolites share common precursor pools, acyl-CoA. Thus, the effects of engineering strategies for heterologous and native secondary metabolite production are often determined by the measurement of pikromycin in Streptomyces venezuelae. It is hard to compare the effectiveness of engineering targets among published data owing to the different pikromycin production media used from one study to the other. To determine the most important nutritional factor and establish optimal culture conditions, medium optimization of pikromycin from Streptomyces venezuelae ATCC 15439 was studied with a statistical method, Plackett-Burman design. Nine variables (glucose, sucrose, peptone, (NH₄)₂SO₄, K₂HPO₄, KH₂PO₄, NaCl, MgSO₄·7H₂O, and CaCO₃) were analyzed for their effects on a response, pikromycin. Glucose, K₂HPO₄, and CaCO₃ were determined to be the most significant factors. The path of the steepest ascent and response surface methodology about the three selected components were performed to study interactions among the three factors, and the fine-tune concentrations for maximized product yields. The significant variables and optimal concentrations were 139 g/1 sucrose, 5.29 g/l K₂HPO₄, and 0.081 g/l CaCO₃, with the maximal pikromycin yield of 35.5 mg/l. Increases of the antibiotics production by 1.45-fold, 1.3-fold, and 1.98-fold, compared with unoptimized medium and two other pikromycin production media SCM and SGGP, respectively, were achieved.

• Smart Structures and Systems
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• 제25권6호
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• pp.719-732
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• 2020

Real-time hybrid simulation (RTHS) which combines physical experiment with numerical simulation is an advanced method to investigate dynamic responses of structures subjected to earthquake excitation. The desired displacement computed from the numerical substructure is applied to the experimental substructure by a servo-hydraulic actuator in real time. However, the magnitude decay and phase delay resulted from the dynamics of the servo-hydraulic system affect the accuracy and stability of a RTHS. In this study, a robust stability analysis procedure for a general single-degree-of-freedom structure is proposed which considers the uncertainty of servo-hydraulic system dynamics. For discussion purposes, the experimental substructure is a portion of the entire structure in terms of a ratio of stiffness, mass, and damping, respectively. The dynamics of the servo-hydraulic system is represented by a multiplicative uncertainty model which is based on a nominal system and a weight function. The nominal system can be obtained by conducting system identification prior to the RTHS. A first-order weight function formulation is proposed which needs to cover the worst possible uncertainty envelope over the frequency range of interest. Then, the Nyquist plot of the perturbed system is adopted to determine the robust stability margin of the RTHS. In addition, three common delay compensation methods are applied to the RTHS loop to investigate the effect of delay compensation on the robust stability. Numerical simulation and experimental validation results indicate that the proposed procedure is able to obtain a robust stability margin in terms of mass, damping, and stiffness ratio which provides a simple and conservative approach to assess the stability of a RTHS before it is conducted.

• 약학회지
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• 제56권4호
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• pp.222-229
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• 2012

In order to determine acetylcholine and choline in the biological samples, the specific enzymes of acetylcholinesterase (AChE) and choline oxidase (ChO), which utilize acetylcholine and choline as substrates, were employed to convert substrates to $H_2O_2$. The produced $H_2O_2$ was coupled to 4-aminoantipyrine/phenol with peroxidase (PO) yielding quinoneimine dye which was measured at 508 nm. In the present enzymatic spectrophotometric analysis the product at the equilibrium state was measured considering accuracy, precision, time and cost of the analysis. The developed analytical method yielded good linearity (calibration curve; $A_{508}$=9534[acetylcholine]+0.009, correlation coefficient ($R^2$); 0.999) with detection limit of $1.11{\times}10^{-7}M$, reasonable precision (relative standard deviation; 0.10~1.62% at $2.5{\times}10^{-6}M{\sim}1.25{\times}10^{-4}M$) and accuracy (relative error; -0.24~0.97% at $4.13{\times}10^{-6}M{\sim}1.01{\times}10^{-4}M$) for acetylcholine chloride standard solution. The concentrations of acetylcholine and choline in human serum were found as $3.20{\times}10^{-5}M$ and $1.14{\times}10^{-4}M$, respectively. The brain tissues of Sprague-Dawley strain rat contained 9.82${\mu}g/g$ of acetylcholine and 6.53 ${\mu}g/g$ of choline in the cerebrum, while 7.37 ${\mu}g/g$ of acetylcholine and 5.34 ${\mu}g/g$ of choline in the cerebellum.

• Archives of Pharmacal Research
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• 제29권8호
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• pp.707-711
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• 2006

Bifidobacteria-loaded alginate poly-l-lysine microparticles (bap microparticles) were prepared using an air atomization method and then freeze-dried. The viability of the bap microparticles was investigated as a function of the amount of the bifidobacteria cultures, and the addition of a yeast extract, cryoprotectants, antioxidants and neutralizer. The size of the bap microparticles with and without the bifidobacteria was $84.8{\pm}28.5\;{\mu}m$ ($mean{\pm}standard$ deviation) and $113.1{\pm}38.5\;{\mu}m$, respectively. The surface morphology was slightly ellipsoid and wrinkled regardless of the incorporating bifidobacteria. The viability gradually decreased with increasing freeze-drying time. Free-flowing powdered bap microparticles were obtained at least 12 h after freeze-drying the wetted slurry of bap microparticles. However, the particles tended to aggregate when either lactose or ascorbic acid was added. The addition of a yeast extract, cryoprotectants (glycerol and lactose), antioxidants ($NaHSO_3$ and ascorbic acid) and neutralizer $(Mg_3(PO_4)_2)$ resulted in a significantly higher viability of the bifidobacteria in the bap microparticles after freeze-drying (0.34-1.84 log) compared with the culture alone.

• 천문학논총
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• 제30권2호
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• pp.605-607
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• 2015

The development of time-frequency analysis techniques allow astronomers to successfully deal with the non-stationary time series that originate from unstable physical mechanisms. We applied a recently developed time-frequency analysis method, the Hilbert-Huang transform (HHT), to two non-stationary phenomena: the superorbital modulation in the high-mass X-ray binary SMC X-1 and the quasi-periodic oscillation (QPO) of the AGN RE J1034+396. From the analysis of SMC X-1, we obtained a Hilbert spectrum that shows more detailed information in both the time and frequency domains. Then, a phase-resolved analysis of both the spectra and the orbital profiles was presented. From the spectral analysis, we noticed that the iron line production is dominated by different regions of this binary system in different superorbital phases. Furthermore, a pre-eclipse dip lying at orbital phase ~0:6-0:85 was discovered during the superorbital transition state. We further applied the HHT to analyze the QPO of RE J1034+396. From the Hilbert spectrum and the O-C analysis results, we suggest that it is better to divide the evolution of the QPO into three epochs according to their different periodicities. The correlations between the QPO periods and corresponding fluxes were also different in these three epochs. The change in periodicity and the relationships could be interpreted as the change in oscillation mode based on the diskoseismology model.

• 한국세라믹학회지
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• 제35권10호
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• pp.1040-1048
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• 1998

Ferroelectric properties of{{{{ { { { {SrBi }_{2 }Ta }_{2-x }Nb }_{x }O }_{9 } }} (SBIN) thin films were affected by the amount of Bi content in SBTN. The addition of Bi into the SBTN films could be accomplished by heat treating SBTN/Bi2O3/SBTN het-erostructures fabricated by r.f. magnetron sputtering method. The variation of Bi content was controlled by changing the thickness of the sandwiched Bi2O3 in SBTN/Bi2O3/SBTN heterostructure from 50 to 400$\AA$. As changing the thickness of the sandwiched Bi2O3 in Bi2O3 films was increased from 0 to 100$\AA$ the grain grew faster and the ferroelectric pro-perties were improved. On the other hand when the thickness of Bi2O3 films was thicker than 150$\AA$ the fer-roelectric properties were deteriorated Especially for SBTN thin films inserted by 400$\AA$ Bi2O3 layer a Bi2Phase appeared as a second phase resulting in poor ferroelectric properties. The maximum remanent po-larization (2Pr) and coercive field(Ec) were obtained for the SBTN/Bi2O3/(100$\AA$)/SBTN thin films. In this case 2Pr and Ec were 14.75 $\mu$C/cm2 and 53.4kV/cm at an applied voltage of 3V respectively.

• 한국정보통신학회논문지
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• 제4권1호
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• pp.191-200
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• 2000

VTS에서는 소형 선박들에 대한 운항정보의 파악이 어려우므로 관제에 애로가 많다. 즉, GMDSS의 대상이 아닌 소형 선박들이 평상시에 선명 및 위치정보를 전송하고, VTS에서는 입ㆍ출항하는 모든 선박들의 선명과 위치를 용이하게 확인하고 항내에서의 해난사고가 발생하지 않도록 통제할 수 있는 시스템이 필요한 실정이다. 본 연구의 항행정보 전송관리시스템은 micro-processor를 이용하여 CPS의 데이터 중에서 위치와 시간정보를 추출하고 여기에 선박의 ID를 추가하여 2,400[bps]의 저속으로 447[MHz], FSK의 송신기로 전송할 수 있는 시스템을 구현하였다. VTS에서는 이것을 수신, 복조하여 선박의 항행상태를 확인할 수 있다. 실험단계에서는 목포항을 중심으로 항해중의 데이터를 전송하였고, 수신점에서는 해도상에 실시간으로 위치를 표시하는 소프트웨어를 개발하였다. 원거리의 서비스를 위하여 기존의 SSB 통신망에 접속할 수 있는 하드웨어적인 융통성도 고려하였다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2011년도 추계학술대회
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• pp.375-378
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• 2011

컴퓨터 언어를 배우는 학습자는 다양한 분야에 적합한 프로그래밍 언어를 배우고 텍스트 기반으로 된 프로그래밍을 하는 것이 매우 어렵다고 생각한다. 이러한 문제를 쉽게 풀기 위한 한 방법이 프로그램을 비주얼로 표현하는 것이다. 기존의 시각 프로그래밍인 Visual C++, Visual Basic, Delphi와 같은 비주얼 언어는 외부 인터페이스는 비주얼 컴포넌트로 표현되고 컴포넌트의 작동에 대해서는 텍스트 기반으로 표현한다. 이러한 프로그램을 배우는 학습자들은 컴포넌트 작동에 대한 텍스트 프로그래밍에 대해 어려워하고 있으며 프로그래밍을 싫어하는 한 요소가 되었다. 논문에서는 이러한 문제를 해결하기 위해 논리적 사고를 표현하면서 객체지향을 지원하기 위해 UML을 도입하고 텍스트 프로그래밍 요소를 비주얼 프로그래밍 요소로 대체하기 위해 객체지향을 지원하는 LabVIEW OOP를 사용하여 학습자들에게 프로그래밍 교육을 하는 방법을 제시하였다. 또한, 제시된 프로그래밍 교육 방법에 대해 설문조사를 실시하여 교육적인 효과를 분석하였다.

• 한국정보통신학회논문지
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• 제18권3호
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• pp.742-748
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• 2014

객체 지향 시각 프로그래밍 교육에 대한 연구는 학생들이 프로그램 개발을 진행하는 과정 혹은 프로그래밍을 교수하는 방법론과 프로그램 개발을 위한 적합성 분석 및 설계 방법론을 찾는 것과 관련된다. 학생들이 프로그래밍 교육에서 학습에 어려움을 겪고 있는 객체 지향 프로그램 개발 능력을 향상시킬 수 있는 교육 방법으로 이 논문에서는 컴퓨터 프로그래밍 교육에서 객체 지향 시각 프로그래밍 교육을 적용하고 평가하기 위한 평가 지표를 개발하고, Alice 프로그래밍을 통한 시각 프로그래밍 교육 방법론과 교과과정을 도입한다. 이 논문에서 제시된 시각 프로그래밍 교육의 평가 지표는 시각 프로그래밍 언어/도구를 사용할 때 학생들의 프로그래밍 교육에 대한 적합성을 측정하고 분석하여 학생들의 이해력, 추상화 능력, 프로그램 구현 능력과 학생들의 수준별 적합성을 측정하고 분석한다.