• Journal of Environmental Health Sciences
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• v.19 no.3
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• pp.22-28
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• 1993

In order to investigate the hygienic chemical conditions of farm waters used as the potable and cleaning water for cow, we examined the pH, turbidity, KMnO$_4$ consumption, total hardness, chlorine, sulfate, NH$_3$-N, NO$_3$-N, lead, maganese, copper, zinc, fluoride and chrome for 78 farm waters around Kyunggi Province. Of 78 farm waters tested, average pH was 6.70+_0.06, turbidity 0.724 $\pm$ 0.081, KMnO$_4$ consumption 4.200 $\pm$ 0.256 mg/l, total hardness 107.46 $\pm$ 6.90 mg/l, NH$_3$-N 0.043 $\pm$ 0.037 mg/l, NO$_3$-N 8.096 $\pm$ 0.652 mg/l, chlorine 21.414 $\pm$ 2.187 mg/l, sulfate 12.737 $\pm$ 1.511 mg/l, lead 0.076 $\pm$ 0.001 mg/l, manganese 0.029 $\pm$ 0.004 mg/l, copper 0.018 $\pm$ 0.002 mg/l, zinc 0.055 $\pm$ 0.005 mg/l, chrome 0.048 $\pm$ 0.002 mg/l and fluorine 0.011 $\pm$ 0.001 mg/l. According to the geological characteristics, the concentrations of total hardness, NO$_3$-N, pH and chlorine in farm waters of Hwasung gun were higher than those in Yangpyung and Kwangju gun. In hygienic chemical items tested, there were high significanc among NO$_3$-N, total hardness, sulfate and chlorine. KMnO$_4$ consumption was significant with NH$_3$-N, sulfate and pH. But in heavy metals, there were significance between lead and copper, copper and chrome, and copper and fluorine.

• Journal of Chest Surgery
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• v.33 no.3
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• pp.221-229
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• 2000

Background: Thromboxane A2 and endothelin-1 are the potent vasoconstrictors affecting pulmonary pathophysiology in response to whole body inflammatin following CPB. Aprotinin, as an antiiflammatory agent, may decrease the release of such vasoactive substance from pulmonary tissues, preventing pulmonary hypertension after cardiopulmonary bypass. Material and Method: Ten mongrel dogs(Bwt. ac. 20kg) were subjected to cardioupulmonary bypass for 2 hours and postbypass pulmonary vascular resistance(0, 1, 2, 3 hours) were compared with prebypass level. The dogs were divided into 2 groups; control group(n-5) and aprotinin group(n=5). In the aprotinin group, aprotinin was administered as follows; 50,000 KIU/kg mixed in pump priming solution, 50,000 KIU/kg prebypass intravenous infusion over 30 minutes, 10,000 KIU/kg/hour postbypass continuous infusion. Prebypass and postbypass 0, 1, 2, 3 hour pulmonary vascular resistance were measured. At prebypass and postbypass 0, 90, 180 minutes, blood samples were obtained from pulmonary arterial and left atrial catherers for the assay of plasma thromboxane B2 a stable metabolite of thromboxane A2, and endothelin-1 concentrations. Result: The ratios of pustbypass over prebypass pulmonary vascular at postbypass 0, 1, 2, 3 hours were 1.28$\pm$0.20, 1.82$\pm$0.23, 1.90$\pm$0.19, 2.14$\pm$0.18 in control group, 1.58$\pm$0.18, 1.73$\pm$0.01, 1.66$\pm$0.10, 1.50$\pm$0.08 in aprotinin group ; the ratios gradually increased in control group while decreased or fluctuated after postbypass 1 hour in aprotinin group. There was statistically significant difference between control group and aprotinin group at postbypass 3 hours(P=0.014). Pulmonary arterial plasma concentration of thromboxane B2(pg/ml) at prebypass, postbypass 0, 90, 180 minutes were 346.4$\pm$61.9, 529.3$\pm$197.6, 578.3$\pm$255.8, 493.3$\pm$171.3 in control group, 323.8$\pm$118.0, 422.6$\pm$75.6, 412.3$\pm$59.9, 394.5$\pm$154.0 in aprotinin group. Left atrial concentrations were 339.3$\pm$89.2, 667.0$\pm$65.7, 731.2$\pm$192.7, 607.5$\pm$165.9 in control group, 330.0$\pm$111.2, 468.4$\pm$190.3, 425.4$\pm$193.6, 4.7.3$\pm$142.8 in aprotinin group. These results showed decrement of pulmonary thromboxane A2 generation in aprotinin group. Pulmonary arterial concentrations of endothelin-1(fmol/ml) at the same time sequence were 7.84$\pm$0.31, 13.2$\pm$0.51, 15.0$\pm$1.22, 16.3$\pm$1.73 in control group, 7.76$\pm$0.12, 15.3$\pm$0.71, 22.6$\pm$6.62, 14.9$\pm$1.11 in aprotinin group. Left atrial concentrations were 7.61$\pm$17.2, 57.1$\pm$28.4, 18.9$\pm$18.2, 31.5$\pm$20.5 in control group, 5.61$\pm$7.61, 37.0$\pm$26.2, 28.6$\pm$21.7, 37.8$\pm$30.6 in aprotinin group. These results showed that aprotinin had no effect on plasma endothelin-1 concentration after cardiopulmonary bypass. Conclusion: Administration of aprotinin during cardiopulmonary bypass could attenuate the increase in pulmonary vascular resistance after bypass. Inhibition of pulmonary thromboxane A2 generation was thought to be one of the mechanism of this effect. Aprotinin had no effect on postbypass endothelin-1 concentration.

• Journal of Veterinary Clinics
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• v.9 no.1
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• pp.267-271
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• 1992

Present study was undertaken in order to evaluate the cadmium contents of various feedstuffs produced in Chonbuk area. Fifty-five samples were collected from 5 regions. All of the samples were dry-ashed and analyzed for cadmium content using atomic absorption spectrophotometer. The results obtained were summarized as followed : 1. The cadmium content in $\mu\textrm{g}$/g of agriculture by-products were measured with the following mean values and ranges : soybean pod 3.15${\pm}$0.51(2.40∼3.81), rice bran 2.87${\pm}$0.23(2.50∼3.09), rice straw 1.66${\pm}$0.85(1.08∼3.14), rice hull 0.86${\pm}$0.45(0.41∼1.35). 2. The cadmium content in $\mu\textrm{g}$/g of pasture plants were measured with the following mean values and ranges : kudzu 5.65${\pm}$1.00(4.87∼7.29), sagebrush 4.86${\pm}$1.24(2.89∼6.24), clove, 4.28${\pm}$0.75(2.99∼4.86), lespedeza 3.99${\pm}$1.21(2.38∼4.94), Korean lawn grass 2.24${\pm}$1.04(1.33∼3.44), reed 1.99${\pm}$0.95(0.88∼2.91), cornstalk 1.61${\pm}$0.99(0.38∼3.12). 3. The regional mean values for all kinds of samples were Okgu-gun 3.19${\pm}$2.09$\mu\textrm{g}$/g, Mooju-gun 3.15${\pm}$1.73$\mu\textrm{g}$/g, Wanju-gun 3.05${\pm}$1.76$\mu\textrm{g}$/g, Namwon-gun 2.85${\pm}$1.70$\mu\textrm{g}$/g, Jeongup-gun 2.85${\pm}$1.25$\mu\textrm{g}$/g.

• Journal of Oriental Neuropsychiatry
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• v.4 no.1
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• pp.121-134
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• 1993

This study was conducted in order to study the anti-stress effect of Kyogamdan and Sohaphyangwon, and the changes of serum catecholamine, aldosterone and cortisol levels were measured. In this study author gave immobilization stress to rats and got the following results. 1. The contents of norepinephrine in control group were 4.26 ${\pm}$ 0.50, 3.72 ${\pm}$ 0.31ng/ml 3hr, 6hr after an oral administration of Nacl, but in sample A the contents were 3.12 ${\pm}$ 0.33, 3.20 ${\pm}$ 0.41ng/ ml and in sample B were 3.50 ${\pm}$ 0.65, 2.49 ${\pm}$ 0.55ng/ ml. The difference was obvious. 2. The contents of epinephrine in control group were 7.01 ${\pm}$ 0.85, 6.50 ${\pm}$ 0.68ng/ ml after 3hr, 6hr since Nacl was taken, but in sample A the contents were 4.95 ${\pm}$ 0.67, 4.45 ${\pm}$ 0.58ng/ ml and in sample B were 5.87 ${\pm}$ 0.87, 4.33 ${\pm}$ 0.59ng/ ml. The real significance lies in 6hr after administration of Sample A and B. 3. The contents of cortisol in control group were 3.39 ${\pm}$ 0.04, 3.73 ${\pm}$ 0.04ng / ml, but in sample A were 2.99 ${\pm}$ 0.02, 4.74 ${\pm}$ 0.04, and in sample B were 2.69 ${\pm}$ 0.03, 3.79 ${\pm}$ 0.03ng / ml. The real significance lies in 3hr since sample A and B were taken. 4. The aldosterone contents in control group were 1121.90 ${\pm}$ 71.90, 1454.30 ${\pm}$ 168.50 pg / ml, but in sample A were 1198.20 ${\pm}$ 69.10, 1257.50 ${\pm}$ 180.70 and in sample B were 776.30 ${\pm}$ 79.10, 1367.00 ${\pm}$ 170.10 pg / ml. The real significance lies in 3hr Sample B was taken. Base on the results above, it may be concluded that Kyogamdan and Sohaphyangwon are effective to prevent the changes by stress and Sohaphyangwon is better effective than Kyogamdan to prevent stress.

• Korean Journal of Agricultural Science
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• v.34 no.1
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• pp.19-35
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• 2007

The present study was carried out to examine the effect of EGF and IGF-I in vitro maturation (IVM) of porcine oocytes and development of porcine IVM/IVF embryos. The results were summarized as follows : 1. The rates of nuclear maturation, penetrated oocytes, pronuclear formation, polyspermic oocytes and mean numbers of the penetrated sperm were not different in NCSU-23 maturation medium with 0, 1, 5 and 10 ng/ml EGF and IGF-I (P>0.05). 2. The rates of blastocyst formation at day 7 after in vitro fertilization in 0, 1, 5 and 10 ng/ml EGF groups were $11.2{\pm}1.5%$, $15.0{\pm}8.3%$, $16.8{\pm}2.8%$ and $21.4{\pm}2.0%$, also 0, 1, 5 and 10 ng/ml IGF-I groups were $11.2{\pm}1.5%$, $15.0{\pm}8.3%$, $16.8{\pm}2.8%$ and $21.4{\pm}2.0%$, respectively. In the total cells case, EGF groups were $22.8{\pm}3.7$, $25.7{\pm}5.5$, $26.0{\pm}4.2$ and $35.1{\pm}4.7$, also IGF-I groups were $21.5{\pm}3.7$, $25.2{\pm}2.8$, $26.2{\pm}2.9$ and $33.2{\pm}3.6$, respectively. Both 10 ng/ml EGF group and 10 ng/ml IGF-I group were significantly higher than those of other treatment groups (P<0.05). 3. The rates of blastocyst formation at day 7 in the NCSU23 culture medium of porcine IVF-produced embryos with 0, 1, 5, and 10 ng/ml EGF groups were $14.0{\pm}1.7%$, $16.2{\pm}1.4%$, $16.9{\pm}1.2%$ and $23.1{\pm}1.6%$, also 0, 1, 5, 10 ng/ml IGF-I groups were $13.6{\pm}1.7$, $15.7{\pm}4.5$, $16.0{\pm}0.2$ and $25.0{\pm}0.8$, respectively. And in the total cells case, EGF grups were $21.8{\pm}2.9$, $25.2{\pm}2.8$, $39.7{\pm}2.7$ and $46.2{\pm}3.6$, also IGF-I groups were $20.7{\pm}2.9$, $26.2{\pm}2.9$, $24.6{\pm}2.4$ and $46.1{\pm}3.5$, respectively. Both 10 ng/ml EGF group and 10 ng/ml IGF-I group were significantly higher than those of any other treatment groups (P<0.05). In conclusion, these results suggested that the addition of 10 ng/ml EGF and IGF-I were effective on the blastocyst formation and total cells of blastocysts.

• The Journal of Korean Society for Radiation Therapy
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• v.16 no.2
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• pp.9-17
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• 2004

Purpose : Although Improve of CT, MRI Radio-diagnosis and Radiation Therapy Planing, but we still use ICRU38 Planning system(2D film-based) broadly. 3-Dimensional ICR plan(CT image based) is not only offer tumor and normal tissue dose but also support DVH information. On this study, we plan irradiation-goal dose on CTV(CTV plan) and irradiation-goal dose on ICRU 38 point(ICRU38 plan) by use CT image. And compare with tumor-dose, rectal-dose, bladder-dose on both planning, and analysis DVH Method and Material : Sample 11 patients who treated by Ir-192 HDR. After 40Gy external radiation therapy, ICR plan established. All the patients carry out CT-image scanned by CT-simulator. And we use PLATO(Nucletron) v.14.2 planing system. We draw CTV, rectum, bladder on the CT image. And establish plan irradiation-$100\%$ dose on CTV(CTV plan) and irradiation-$100\%$ dose on A-point(ICRU38 plan) Result : CTV volume($average{\pm}SD$) is $21.8{\pm}26.6cm^3$, rectum volume($average{\pm}SD$) is $60.9{\pm}25.0cm^3$, bladder volume($average{\pm}SD$) is $116.1{\pm}40.1cm^3$ sampled 11 patients. The volume including $100\%$ dose is $126.7{\pm}18.9cm^3$ on ICRU plan and $98.2{\pm}74.5cm^3$ on CTV plan. On ICRU planning, the other one's $22.0cm^3$ CTV volume who residual tumor size excess 4cm is not including $100\%$ isodose. 8 patient's $12.9{\pm}5.9cm^3$ tumor volume who residual tumor size belows 4cm irradiated $100\%$ dose. Bladder dose(recommended by ICRU 38) is $90.1{\pm}21.3\%$ on ICRU plan, $68.7{\pm}26.6\%$ on CTV plan, and rectal dose is $86.4{\pm}18.3\%,\;76.9{\pm}15.6\%$. Bladder and Rectum maximum dose is $137.2{\pm}50.1\%,\;101.1{\pm}41.8\%$ on ICRU plan, $107.6{\pm}47.9\%,\;86.9{\pm}30.8\%$ on CTV plan. Therefore CTV plan more less normal issue-irradiated dose than ICRU plan. But one patient case who residual tumor size excess 4cm, Normal tissue dose more higher than critical dose remarkably on CTV plan. $80\%$over-Irradiated rectal dose(V80rec) is $1.8{\pm}2.4cm^3$ on ICRU plan, $0.7{\pm}1.0cm^3$ on CTV plan. $80\%$over-Irradiated bladder dose(V80bla) is $12.2{\pm}8.9cm^3$ on ICRU plan, $3.5{\pm}4.1cm^3$ on CTV plan. Likewise, CTV plan more less irradiated normal tissue than ICRU38 plan. Conclusion : Although, prove effect and stability about previous ICRU plan, if we use CTV plan by CT image, we will reduce normal tissue dose and irradiated goal-dose at residual tumor on small residual tumor case. But bigger residual tumor case, we need more research about effective 3D-planning.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.31 no.3
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• pp.1-11
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• 2018

Objectives : The purpose of this study is to analyze the correlation between fine dust(PM10.5, PM2.5) and the number of acute/chronic sinusitis patients. Methods : A simple regression analysis was performed based on the concentration of PM10 and PM2.5 as independent variables and the number of acute/chronic sinusitis patients as dependent variables. Results : As a result of simple regression analysis, if PM10 increases by $1{\mu}g/m^3$, the number of acute sinusitis patients increases by 7,000.291(P<.001, 95%CI :4,951.983-9,048.600). If PM2.5 increases by $1{\mu}g/m^3$, the number of acute sinusitis patients increases by 17,524.476.(P<.001, 95%CI:9,728.725-25,320.228) In addition, PM10 increases by $1{\mu}g/m^3$, the number of acute sinusitis patients increases by 3,163.471 (P<.001, 95% CI:2,268.642-4,058.301). If PM2.5 increases by $1{\mu}g/m^3$, the number of chronic sinusitis patients increases by 8,651.644.(P<.001, 95%CI:5,115.697-12,187.592) Conclusions : Both PM10 and PM2.5 are correlated with changes in the number of sinusitis patients. PM2.5 has effect on the number of patients than PM10. PM10 is the highest correlation in their 50s, PM2.5 in their 60s and 70s.

• Korean Journal of Veterinary Research
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• v.37 no.4
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• pp.899-909
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• 1997

The aim of this study was to assess the estimates of the time of ovulation and mating derived by plasma progesterone concentration. The 40 mature Korea Jin-do bitches were monitored to determine the plasma progesterone concentrations from proestrus to parturition. Gestation length in the 30 pregnant bitches was $63.9{\pm}2.3$ ($mean{\pm}SD$) days in multiparous bitches and $61.8{\pm}3.6$ days in primiparous bitches when Day 0 was timed from the first day of male acceptance, and $61.4{\pm}1.8$ days and $61.3{\pm}2.7$ days when Day 0 was timed from the day of first mating, respectively. Also, gestation length was $63.1{\pm}1.4$ days, $62.4{\pm}1.1$ days and $61.5{\pm}0.9$ days in multiparous bitches, and $62.6{\pm}1.4$ days, $62.4{\pm}2.0$ days and $61.6{\pm}2.3$ days in primiparous bitches when Day 0 was timed from the day that plasma progesterone concentration was first increased above 2.0, 3.0 and 4.0ng/ml, respectively, and $53.8{\pm}3.1$ days and $54.8{\pm}2.6$ days when Day 0 was timed from the last day of male acceptance, respectively. In 30 pregnant bitches, plasma progesterone concentration was $0.2{\pm}0.2ng/ml$ in multiparous bitches and $0.7{\pm}0.8ng/ml$ in primiparous bitches at the first day of vulval bleeding, $1.9{\pm}1.0$ and $3.3{\pm}2.7ng/ml$ at the first day of male acceptance, $7.0{\pm}4.0$ and $9.3{\pm}6.2ng/ml$ at the day of first mating, and $25.1{\pm}6.3$ and $22.8{\pm}10.3ng/ml$ at the last day of male acceptance, respectively. When Day 0 was timed from the day of parturition, plasma progesterone concentration at Day -62, Day -63 and Day -64 was $4.7{\pm}2.7ng/ml$, $3.5{\pm}2.2ng/ml$ and $1.7{\pm}0.9ng/ml$ in multiparous bitches, and $5.3{\pm}4.4ng/ml$, $3.2{\pm}3.7ng/ml$ and $2.0{\pm}1.9ng/ml$ in primiparous bitches, respectively. When Day 0 was timed from the day that plasma progesterone concentration was first increased above 3.0ng/ml after the first day of vulval bleeding, plasma progesterone concentration at Day 61 and Day 62 was $2.7{\pm}2.2ng/ml$ and $1.4{\pm}1.9ng/ml$ in multiparous bitches, and $3.4{\pm}5.2ng/ml$ and $3.7{\pm}5.6ng/ml$ in primiparous bitches, and $0.8{\pm}0.7ng/ml$ and $0.9{\pm}0.4ng/ml$ at Day 63, respectively. It was that bitches were mated when plasma progesterone concentraion was 1.9 to 14.2ng/ml and 3.5 to 20.0ng/ml in multiparous and primiparous bitches, which was between first day before ovulation and fourth day after ovulation. And pregnancy rate was 92% (23/25). From these data, ovulation was estimated to occur the day when plasma progesterone concentration was first increased above 3.0ng/ml after the first day of vulval bleeding. It was estimated that mating time was the day when plasma progesterone concentration was between 1.9 and 20.0ng/ml, and best time for mating was between 3.0 and 8.0ng/ml of plasma progesterone concentration.

• Journal of Korean Public Health Nursing
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• v.16 no.2
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• pp.445-453
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• 2002

Purpose: This study has been designed to evaluate occupational health services on workers with hypertension Method: Study participants were 108 workers having a diagnosed hypertension. The instrument used for this study was the questionnaire developed by Cho(1998). Analysis of the data was done with SPSS Win 10.0 for descriptive statistics, Correlation coefficient. Results: 1. The mean score of process domain was $3.77\pm.43$ The score of process domains were usefulness of health management$(3.98\pm.49)$, education or counselling$(3.87\pm.53)$, follow up in medical examination$(3.79\pm.58)$, usefulness of providing materials$(3.53\pm.62)$, perception of medical examination $(3.37\pm.80)$ 2. The mean score of outcome domain was $3.47 \pm.44$ The score of outcome domains were obstructiveness of social life$(3.90\pm.78)$, habits of living $(3.41\pm.76)$, blood pressure change $(3.25\pm.81)$, perception of seriousness$(3.02\pm.88)$. 3. Blood pressure change was significant correlated with education or counselling(r=.31) and usefulness of providing materials(r=.28).

• Journal of Environmental Science International
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• v.26 no.1
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• pp.29-36
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• 2017

Aerosol mass size distributions were investigated at 865 m high the of Jirisan national park. A nanosampler cascade impactor was used to collect aerosols. The atmospheric aerosol particles had a unimodal mass size distribution, which peaked at $0.5-1.0{\mu}m$, and a mass aerodynamic diameter of $1.13{\mu}m$. The annual average concentrations of TSP, $PM_{10}$, $PM_{2.5}$, $PM_1$, $PM_{0.5}$ and $PM_{0.1}$ were $20.9{\mu}g/m^3$, $19.3{\mu}g/m^3$, $14.9{\mu}g/m^3$, $10.7{\mu}g/m^3$, $5.3{\mu}g/m^3$, $1.2{\mu}g/m^3$, respectively. TSP concentrations were below $30{\mu}g/m^3$ during the sampling period. On average $PM_{10}$, $PM_{2.5}$, $PM_1$, $PM_{0.5}$ and $PM_{0.1}$ made up 0.91, 0.70, 0.41, 0.19 and 0.07 of TSP, respectively. The annual average of PM2.5/PM10 ratio was 0.77.