• 한국전자파학회논문지
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• 제18권12호
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• pp.1337-1344
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• 2007

이동 통신 단말기 내장형 안테나의 급전 부분에 역 파이 형태의 급전부를 채택함으로써 이득이 증가함을 보인다. PIFA, IFA 등과 같은 안테나 급전 부분을 수정하여 안테나와 같은 방향으로 전류가 흐를 수 있도록 하면 T 정합 이론을 적용할 수 있다. 따라서 T 정합 이론을 근거로 하는 역 파이 급전은 안테나의 방사 저항을 높이고 더불어 이득도 증가시킬 수 있다. 역 파이 급전 이론의 타당성을 밝히기 위하여 기존의 GSM/ DCS 2중 대역 PIFA에 적용하여 제반 특성을 측정한다. 측정 결과, 공진 주파수의 이동은 없으며, 채널별 평균 이득은 역 파이 급전 PIFA가 기존 PIFA에 비해 GSM 대역에서는 $0.23{\sim}0.84$ dB, DCS 대역에서는 $0.01{\sim}1.74$ dB 향상됨을 보인다.

• 미생물학회지
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• 제6권4호
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• pp.122-130
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• 1968

Action of various wavelengths of visible light on ultraviolet-radiation damage to haploid yeast cells, Saccharomyces cerevisiae 23971, was studied. The results were obtained on the basis of the survival and respiration rates by pre- and post-illuminations of various wavelengths before and after U.V.-irradiations on the yeast cells. Among the wavelengths tested, 635 $m{\mu}$, 429 $m{\mu}$ and white light which caused increase of respiration in pre-treatment alone, induced less resistance to the U. V.-damage than in the control, in both pre- and U.V.-treatment. On the contrary, such wavelengths as 574 $m{\mu}$and 530 $m{\mu}$, showing a weak effect on respiration in pre-treatment increased the susceptability to U.V.-radiation. Photoinactivation was generally obtained by both pre- and post- illuminations along with U.V.-treatment. At 635 $m{\mu}$ the PI rate was the lowest and also a low PI rate was shown at 429 $m{\mu}$. But 429 $m{\mu}$, in the post-treatment of the yeast cells pre-treated by the white light and the darkness respectively, showed the highest PI rate. In both pre- and post- treatment of 574, 530 and 473 $m{\mu}$,the PI rates were high to the same degree. Post-treatments of the wavelengths on U.V.-treated yeasts incubated rather under the white light than the darkness induced lower PI rate. It is assumed that there are great differences in action even of the same wavelength, depending upon the various combination of pre- and post-treatments, and that, moreover, the action of various wavelengths of visible light on U.V.-damage on the cells are concerned with the doses and dose rates of U.V. and visible lights. These observations led to an interpretation that each wavelength of visible light might exert distinctively different effects oil U. V.-damage, mainly causing the inhibition or stimulation of enzymes in the yeast cells.

• 한국방재학회 논문집
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• 제4권1호
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• pp.15-24
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• 2004

일반적으로, 2개의 I형 거더로 이루어진 ${\pi}$형거더는 공기역학적으로 불안하여 내풍설계에 있어 매우 불리 한 것으로 알려져 있다. 공기역학적 진동은 구조물의 강성이나 감쇠의 향상, 단면 형상의 연구 등에 의해 억제될 수 있으므로 본 연구에서는 ${\pi}$ 형단면을 가진 4경간 사장교에 대해 영각과 공기역학적 제진장치의 추가로 인한 단면의 변화에 따른 2차원 진동실험을 통하여 공기역학적 특성을 파악하도록 하였다. 등류와 난류에서의 실험결과 본 교량단면은 기본단면만으로도 내풍안정성을 충분히 갖추고 있기 때문에 페어링(Fairing) 및 베플(Baffle Plate) 등의 추가적인 공기역학적 제진장치가 필요하지 않을 것으로 판단된다. 이는 본 교량의 경우 주경간이 230m인 4경간으로 이루어져 있어 비슷한 단면을 가진 교량에 비하여 수직 및 비틀림 진동수가 크고 강성이 크기 때문에 설계풍속 내에서 공기역학적으로 안정한 것으로 보여진다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권7호
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• pp.2645-2651
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• 2015

Background: The phosphatidylinositol 3'-kinase/Akt (PI3K/Akt) pathway is a key regulator for HER2-overexpressing breast cancer, but data about whether activation of PI3K/Akt is associated with poor prognosis and resistance to trastuzumab therapy is controversial. In this study we investigated predictive and prognostic significance of expression of p27, Akt, PTEN and PI3K, which are components of the PI3K/Akt signaling pathway, in HER2-positive metastatic breast cancer (MBC), retrospectively. Materials and Methods: Fifty-four HER2-positive MBC patients who had received first-line trastuzumab-based therapy were recruited for the study group. All of the patient's breast tissue samples were examined for p27 and Akt expression. In addition, twenty-five patients with sufficient amount of tumor tissue were also examined for PTEN and PI3K expression. p27, Akt, PTEN and PI3K were evaluated by immunohistochemistry and their relationship with patient demographic features, tumor characteristics, response to trastuzumab-based treatment and survival outcomes were analyzed. Results: p27, Akt, PTEN and PI3K were positive in 25.9%, 70.4%, 24% and 96% of the cases, respectively. Nomne were significantly associated with response to trastuzumab and time to progression (TTP). A trend toward statistical significance for longer overall survival (OS) was found for PTEN-positive patients (p=0.058); there was no significant relationship between the other immunohistochemical variables and OS. When we analyzed groups regarding co-expression, the PTEN-negative/Akt-negative group had a significantly lower objective response rate (ORR) (20% vs 80%, p=0.023) and the PTEN-negative/p27-negative and PTEN-negative/Akt-negative groups had significantly lower median OS compared to other patients (26.4 months vs 76.1 months, p=0.005 and 25.6 months vs 52.0 months, p=0.007, respectively). Conclusions: p27, Akt, PTEN and PI3K expression is not statistically significantly associated with ORR, TTP and OS, individually. However, the combined evaluation of p27, Akt and PTEN could be helpful to predict the response to trastuzumab-based therapy and prognosis in HER2-positive MBC.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2009년도 정보 및 제어 심포지움 논문집
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• pp.85-87
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• 2009

This paper presents a new PID controller for a DC/DC boost converter model that has a parasitic inductor resistance. In order to maintain the robust output regulation property under load variations the proposed controller is designed by using an additional state variable developed via a parallel-damped passivity-based control approach. Simulation results using Matlab/Simulink SimPowerSystems compare the performances of the proposed controller with a conventional PI controller for reference step changes and load uncertainties.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1988년도 한국자동제어학술회의논문집(국내학술편); 한국전력공사연수원, 서울; 21-22 Oct. 1988
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• pp.370-373
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• 1988

Althouah there have been many attempts to control weld quality in resistance spot welding processes, design method for an on-line feedback controller based upon process dynamics has not been suggested. This is due to the fact that the resistance spot welding is a highly complicated process, whice involves the interaction of electrical, thermal, mechanical and metallurgical phenomena. In this paper, an optimal control method based on FDM model with shunt effect is presented, which can regulate the nugget size, at the same time minimizing the control heat input. Optimal PI gain of the controller were determined by numerical optimization. Simulation results show that, as a result of the proposed optimal control, the weld nugget can be made to approach a desired nugget size with less control heat input than that required for the conventional spot welding process in the face of the shunt effect.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2009년도 9th International Meeting on Information Display
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• pp.1430-1432
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• 2009

The effect of different annealing methods on the sheet resistance of indium tin oxide (ITO) on polyimide (PI) substrate has been investigated. As electro-annealing induced the predominant growth of crystallites of ITO thin films along (400) plane, the sheet resistance of ITO films that were electro-annealed for 2 mA at $180^{\circ}C$ considerably decreased from 50 to 28 ${\Omega}/cm^2$.

• 접착 및 계면
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• 제3권1호
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• pp.9-12
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• 2002

In this paper, N,N-m-phenyenedimaleimide (m-PDM), Polyamide Resin (PI) and Metallic dimethacrylate etc. influencing the heat resistance of anaerobic adhesive has been studied, an anaerobic adhesive composition capable of post-cure expansion and $230^{\circ}C$ temperature resistance comprising a multifunctional methacrylate and m-PDM capable of effectuating expansion upon post-cure has been developed. A homogeneous mixture of a monomer and m-PDM are subjected to a first cure heat stage (Room Temperature) wherein a rigid partially-cured plastic is formed and a post-cure heat stage ($150^{\circ}C$) to effectuate permanent expansion of cured adhesive composition.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2001년도 추계학술대회 논문집
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• pp.65-68
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• 2001

In the vector control methods of induction motor, the stator current is divided into the flux and torque component current. By controlling these components respectively, the methods control independently flux and torque as in the DC motor and improve the control effects. To apply the vector control methods, the position of the rotor current is identified. The indirect vector control use the parameters of the machine to identify the position of rotor flux. But due to the temperature rise during machine operation, the variation of rotor resistance degrades the vector control. To solve the problem, the q-axis is aligned to reference frame without phase difference by comparing the real flux component with the reference flux component. Then to compensate the slip, PI controller is used. The proposed method keeps a constant slip by compensating the gain of direct slip frequency when the rotor resistance of induction motor varies. To prove the validations of the proposed algorithm in the paper, computer simulations is executed.

• Molecules and Cells
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• 제41권3호
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• pp.244-255
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• 2018

Low-grade pro-inflammatory state and leptin resistance are important underlying mechanisms that contribute to obesity-associated hypertension. We tested the hypothesis that Astragaloside IV (As IV), known to counteract obesity and hypertension, could prevent obesity-associated hypertension by inhibiting pro-inflammatory reaction and leptin resistance. High-fat diet (HFD) induced obese rats were randomly assigned to three groups: the HFD control group (HF con group), As IV group, and the As IV + ${\alpha}$-bungaratoxin (${\alpha}-BGT$) group (As IV+${\alpha}-BGT$ group). As IV ($20mg{\cdot}Kg^{-1}{\cdot}d^{-1}$) was administrated to rats for 6 weeks via daily oral gavage. Body weight and blood pressure were continuously measured, and NE levels in the plasma and renal cortex was evaluated to reflect the sympathetic activity. The expressions of leptin receptor (LepRb) mRNA, phosphorylated signal transducer and activator of transcription-3 (p-STAT3), phosphorylated phosphatidylinositol 3-kinase (p-PI3K), suppressor of cytokine signaling 3 (SOCS3) mRNA, and protein-tyrosine phosphatase 1B (PTP1B) mRNA, pro-opiomelanocortin (POMC) mRNA and neuropeptide Y (NPY) mRNA were measured by Western blot or qRT-PCR to evaluate the hypothalamic leptin sensitivity. Additionally, we measured the protein or mRNA levels of ${\alpha}7nAChR$, inhibitor of nuclear factor ${\kappa}B$ kinase subunit ${\beta}/nuclear$ factor ${\kappa}B$ ($IKK{\beta}/NF-KB$) and pro-inflammatory cytokines ($IL-1{\beta}$ and $TNF-{\alpha}$) in hypothalamus and adipose tissue to reflect the anti-inflammatory effects of As IV through upregulating expression of ${\alpha}7nAChR$. We found that As IV prevented body weight gain and adipose accumulation, and also improved metabolic disorders in HFD rats. Furthermore, As IV decreased BP and HR, as well as NE levels in blood and renal tissue. In the hypothalamus, As IV alleviated leptin resistance as evidenced by the increased p-STAT3, LepRb mRNA and POMC mRNA, and decreased p-PI3K, SOCS3 mRNA, and PTP1B mRNA. The effects of As IV on leptin sensitivity were related in part to the up-regulated ${\alpha}7nAchR$ and suppressed $IKK{\beta}/NF-KB$ signaling and pro-inflammatory cytokines in the hypothalamus and adipose tissue, since co-administration of ${\alpha}7nAChR$ selective antagonist ${\alpha}-BGT$ could weaken the improved effect of As IV on central leptin resistance. Our study suggested that As IV could efficiently prevent obesityassociated hypertension through inhibiting inflammatory reaction and improving leptin resistance; furthermore, these effects of As IV was partly related to the increased ${\alpha}7nAchR$ expression.