• Journal of Yeungnam Medical Science
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• 제38권2호
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• pp.95-106
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• 2021

Infections involving the heart are becoming increasingly common, and a timely diagnosis of utmost importance, despite its challenges. F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is a recently introduced diagnostic tool in cardiology. This review focuses on the current evidence for the use of FDG PET/CT in the diagnosis of infective endocarditis, cardiac implantable device infection, left ventricular assist device infection, and secondary complications. The author discusses considerations when using FDG PET/CT in routine clinical practice, patient preparation for reducing physiologic myocardial uptake, acquisition of images, and interpretation of PET/CT findings. This review also functions to highlight the need for a standardized acquisition protocol.

• 대한핵의학회지
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• 제36권1호
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• pp.28-33
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• 2002

Lung cancer has become a loading cause of cancer death in Korea. Positron emission tomography was introduced in clinical nuclear medicine in the early 1990s and many studios using this functional imaging technology were performed for evaluation of its clinical utility. I review the current role of positron emission tomography in the diagnosis, staging, and therapy monitoring of lung cancer.

• 대한정형외과학회지
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• 제54권6호
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• pp.509-518
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• 2019

목적: 악성 종양 환자에서 림프절 전이를 발견하는 것은 초기에 정확한 병기 및 예후와 관련된 정보를 알 수 있고 수술 후 보조치료(adjuvant therapy)의 필요성을 평가해서 조기에 치료를 할 수 있도록 해주기 때문에 중요하다. 본 연구를 통해 정형외과 영역의 악성 종양 환자를 평가함에 있어 양전자 방출 컴퓨터 단층 촬영기(positron emission tomography/computed tomography, PET/CT)가 sentinel lymph node biopsy와 비교하여 유용한지를 알아보고자 한다. 대상 및 방법: 2008년부터 2018년까지 악성 근골격계 종양으로 진단받고 PET/CT를 촬영한 환자 251명 중 72명의 환자를 선별하여 후향적 분석을 시행하였다. 림프절 전이가 의심되는 환자군은 조직검사를 시행하였다. 분석은 의무기록, 임상정보, PET/CT 영상 및 판독 소견, 병리 결과를 통해 시행하였으며, 임상경과 및 병리검사 결과를 PET/CT 결과와 비교하여 PET/CT의 정확도를 평가하였다. 결과: 환자의 나이는 14세에서 88세까지 분포하였고, 평균 추시 기간은 2.4년이었으며, 22명에서 림프절의 전이가 확인되었다. 육종 및 비육종 종양에서 PET/CT 영상의 민감도, 특이도, 양성예측도, 음성예측도는 전문가의 소견을 함께 고려할 경우 상당히 상승하는 것을 확인하였다. 결론: 본 연구를 통하여 전문가의 소견을 함께 고려한다면, 림프절의 전이를 발견하는 데 PET/CT의 유용성은 증가할 것으로 생각된다.

• Imaging Science in Dentistry
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• 제36권2호
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• pp.111-116
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• 2006

PET/CT is a new imaging technology that combines high-quality Positron Emission Tomography (PET) and Computed Tomography (CT). This imaging provides simultaneous anatomical and metabolic information. Therefore PET/CT is useful diagnostic modality for early detection of malignant tumor, accurate staging, decision on therapeutic plan, monitoring response to therapy and rapid detection of recurrence. We report oral and maxillofacial cancers diagnosed by using PET/CT and the usefulness of PET/CT in the evaluation of postoperative recurrence.

• Korean Journal of Radiology
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• 제1권1호
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• pp.51-55
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• 2000

Objective: To determine the accuracy of CT and positron emission tomography (PET) in the diagnosis of recurrent uterine cervical cancer. Materials and Methods: Imaging findings of CT and PET in 36 patients (mean age, 53 years) in whom recurrent uterine cervical cancer was suspected were analyzed retrospectively. Between October 1997 and May 1998, they had undergone surgery and/or radiation therapy. Tumor recurrence was confirmed by pathologic examination or follow-up studies. Results: In detecting recurrent uterine cervical cancer, the sensitivity, specificity, and accuracy of CT were 77.8%, 83.3%, and 80.5%, respectively, while for PET, the corresponding figures were 100%, 94.4%, and 97.2%. The Chi-square test revealed no significant difference in specificity (p = .2888), but significant differences in sensitivity (p = .0339) and accuracy (p = .0244). Conclusion: PET proved to be a reliable screening method for detecting recurrent uterine cervical cancer, but to determine the anatomical localization of recurrent tumors, and thus decide an adequate treatment plan, CT was eventually needed.

• Nuclear Medicine and Molecular Imaging
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• 제43권5호
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• pp.505-507
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• 2009

A 60-year-old woman, who had non-small-cell lung cancer (NSCLC) in left lower lobe underwent brain F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) for evaluation of cerebral metastasis. On follow-up FDG-PET/CT, only hypometaolic lesion was detected and progressed in right frontal lobe at 6 months and 10 months, later. Hypermetabolic metastasis was not detected even at last scan time of FDG-PET/CT. Brain MRI showed brain metastasis in right frontal lobe. As might be expected, the physician should take cerebral metastasis into consideration even though there is only hypometabolic change on subsequent FDG-PET/CT in patients with NSCLC.

• 한국멀티미디어학회논문지
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• 제20권6호
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• pp.865-872
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• 2017

Recent advance in electronics and scintillators makes it possible to utilize the time-of-flight (TOF) information in improving image reconstruction of positron emission tomography(PET). In this paper, we propose a TOF-based fast image reconstruction method for PET. The proposed method uses the deconvolution of TOF data for each angle view and the rotational averaging of deconvolved images. Simulation results show an improved performance of the proposed method, as compared with filtered backprojection (FBP) method, TOF-FBP, and TOF version of expectation-maximization(EM) methods. Simulation results also show a great potentiality of the proposed method in limited angle tomography applications.

• Imaging Science in Dentistry
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• 제44권4호
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• pp.325-332
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• 2014

A combination of positron emission tomography (PET) with $^{18}F$-labeled fluoro-2-deoxyglucose ($^{18}F$-FDG) and computed tomography ($^{18}F$-FDG-PET/CT) has increasingly become a widely used imaging modality for the diagnosis and management of head and neck cancer. On the basis of both recent literature and our professional experience, we present a set of principles with pictorial illustrations and clinical applications of FDG-PET/CT in the evaluation and management planning of squamous cell carcinoma of the oral cavity and oropharynx. We feel that this paper will be of interest and will aid the learning of oral and maxillofacial radiology trainees and practitioners.

• 대한방사성의약품학회지
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• 제4권1호
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• pp.32-35
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• 2018

Since utilization of metal is attractive research area applicable to medical applications, several metals have been studied by many scientists. Zr-89 is known as one of important radioisotopes nowadays. Novel ligands for Zr-89 have been developed, and Zr-89-based radiopharmaceuticals have been employed for positron emission tomography (PET) study. In this highlight review, recent advances on Zr-89 utilization for radiophramaceuticals are illustrated.

• 대한방사성의약품학회지
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• 제8권1호
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• pp.25-32
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• 2022

Malignant melanoma has an aggressive nature and high metastatic potential that result in one of the highest cancer mortality rates. Over the past three decades, primary and metastatic melanoma incidence has rapidly increased. The recent advances in diagnostic technology have shown promise, but there is still an enormous need for specific detection methods to diagnose malignant melanoma. Positron emission tomography can visualize a particular biomarker of malignant melanoma and promise a noninvasive image of micrometastases. However, the development of PET radiopharmaceuticals remains necessary for diagnosing malignant melanoma by using positron emission tomography. In this review, the history and a general overview of PET radionuclide labeled benzamide derivatives, including their radiosynthesis, in vivo characterization, and evaluation, are provided as imaging agents for malignant melanoma.