• Title/Summary/Keyword: PCA(Principal Component Analysis

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THE COMBINATION OF CHEMOMETRICS AND 2D NIR CORRELATION SPECTROSCOPY IN THE ANALYSIS OF DENATURATION PROCESS

  • Czarnik-Matusewicz, Boguslawa;Murayama, Koichi;Wu, Yuqing;Ozaki, Yukihiro
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1286-1286
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    • 2001
  • Despite extensive theoretical and experimental studies the structure of the protein-solvent interface is subject of many controversy. Understanding the processes that occur in aqueous solution requires understanding of the solvent influence on the structure of protein. The aim of this study is to investigate the applicability of NIR methods in the study of hydration phenomena in protein solutions. Temperature-induced changes in NIR spectra of -lactoglobulin (BLG) in aqueous solutions have been investigated by means of two-dimensional correlation spectroscopy (2DCOS) and principal component analysis (PCA). With the temperature increase the balance of forces between the BLG's interaction with itself and the BLGs interaction with its environment is disrupted leading to BLG unfolding. Significant differences of 2D signals and distinct discrepancies of loading on PC1 and PC2 were observed as a result of temperature increase. In the native folded conformation of BLC, most of the nonpolar amino acids are hidden in the centre of the structure, out of contact with water molecules, while charged groups are outside, in the contact with water. The polar groups promote low density Ih-type structure in the water outside this first hydration shell. When BLG unfolds it assumes a more extended configuration on which the previously buried nonpolar groups are exposed to water and promote the higher density II-type structure outside its first shell. Detailed assignments of bands attributed to the bulk water, different states of the hydrated water and the changed conformation of BLG are proposed.

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The Analysis of a Process Monitoring system based on Functional Link Associative Network (화학공정 감시를 위한 함수연결연상 신경망 시스템 구현)

  • Yoon En Sup;Cho Jae Kyu;Lee Dong Eon;Kim Yong Ha;Ahn Sung Jun
    • Journal of the Korean Institute of Gas
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    • v.7 no.3 s.20
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    • pp.24-31
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    • 2003
  • To operate process plant safely and economically, process monitoring is very important. There are a great number of data acquired through distributed control system and process information system. Fault monitoring is the task with difficulties owing to not only the huge amount of data, but also nonlinearity of chemical processes. In this research, the program, REFA, based on PCA and functional link associative neural network has developed. REFA has better learning capabilities, generalization abilities, and shorter learning time than existing neural network programs. In this work its usefulness has proven by application to Tennessee Eastman process.

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A Study on the Consciousness of Exhibition Administrator of National Museums (국공립 박물관 전시 행정담당자의 의식 연구)

  • Cha, Dong-Ik
    • Korean Institute of Interior Design Journal
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    • v.19 no.5
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    • pp.182-189
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    • 2010
  • An exhibition administrator, one who works in the exhibition space of museums and exhibition halls, has carried on various tasks in order to improve the exhibition standard and viewer's satisfaction. Although exhibition administrators have a variety of direct perceptions regarding an exhibition in the actual on-site space, a study on their consciousness was absent. Thus, this study was to comprehend the awareness of how the consciousness of exhibition administrators, who directly understand the various matters regarding the exhibition on-site, was structured and to investigate the difference between the consciousness of exhibition viewers and designers. For the study, Q-Methodology, which can scientifically manage the consciousness such as awareness and the acquired attitudes through individual experiences from a specific group, was applied. The classification of 33 Q-methodology research questions was carried out with 18 exhibition administrators, who are working at either national or public museums and exhibition halls in Korea, and the Principal Component Analysis (PCA) using the QUANL PC program was performed. The results of the analysis provided the following 4 types: 'viewer attraction and exhibition method oriented', 'exhibition standard oriented', 'public relations oriented' and 'the public and government's interest oriented'. Each type showed significant characteristics. Additionally, n showed that 'exhibition standard oriented' was the common type after comparing the type of consciousness among the 3 groups of people, such as an exhibition administrator, an exhibition designer, and a viewer. It indicated that the types of 'public relations oriented' and 'the public and government's interest oriented' from the consciousness category for the exhibition administrator were the most independent type, not being found in any of the other groups. And the Significant correlation between the exhibition viewers and designers was identified after examining the Pearson's correlation among the 3 groups.

Statistical Analysis for Turbulence Properties of the Orion Molecular Cloud

  • Yun, Hyeong-Sik;Lee, Jeong-Eun;Choi, Yunhee;Lee, Seokho;Choi, Minho;Kang, Hyunwoo;Tatematsu, Ken'ichi;Offner, Stella S.R.;Gaches, Brandt A.L.;Heyer, Mark H.;Evans, Neal J. II;Yang, Yao-Lun
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.55.5-56
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    • 2016
  • Turbulence plays an important role in molecular clouds. However, the properties of turbulence are poorly understood. In order to study the influence of turbulence in molecular clouds, we need to sample the turbulent properties in the full range of scales down to sonic scale. We mapped the $20^{\prime}{\times}60^{\prime}$ area covering the Orion Molecular Cloud (OMC) 1-4 region in HCN 1-0 and HCO+ 1-0 with Taeduk Radio Astronomy Observatory (TRAO) 14-m telescope as part of the TRAO key science program, "Mapping turbulent properties of star-forming molecular clouds down to the sonic scale (PI: Jeong-Eun Lee)". In addition, we combine our TRAO data with other molecular line maps ($^{13}CO$ 1-0, $C^{18}O$ 1-0, CS 1-0, $N_2H^+$ 1-0) obtained with the Nobeyama Radio Observatory (NRO) 45-m telescope. To analyze these data, we apply statistical methods, the principal component analysis (PCA) and spectral correlation function (SCF), which are known to be useful to study underlying turbulent properties and to quantitatively characterize cloud structure. We will present the preliminary results of observations and analyses.

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Gene Expression Profiling of Early Renal Toxicity Induced by Gentamicin in Mice

  • Oh, Jung-Hwa;Park, Han-Jin;Lim, Jung-Sun;Jeong, Sun-Young;Hwang, Ji-Yoon;Kim, Yong-Bum;Yoon, Seok-Joo
    • Molecular & Cellular Toxicology
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    • v.2 no.3
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    • pp.185-192
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    • 2006
  • To elucidate the molecular mechanisms associated with early renal injury induced by gentamicin, the most commonly used antibiotics worldwide in the treatment of Gram-negative bacterial infections. We have identified genes differentially expressed at different duration of gentamicin administration. C57BL/6 female mice were treated daily with gentamicin (20 mg/kg, 100 mg/kg, and 200mg/kg) for 7 days and then sacrificed at day 1, 3, and 7 after administration. Standard blood biochemistry and histopathological observation indicative of nephrotoxicity were made. Total RNA was extracted from the kidney for microarray analysis using Affymetrix $GeneChip^{\circledR}$. Five hundred and seventy eight genes were identified as being either up-or down-regulated over 2-fold changes during early renal injury (p<0.05) and were analyzed by hierarchical clustering. The results showed that the genes involved in early immune responses were differentially regulated during early renal injury. Principal component analysis (PCA) confirmed sample separation according to the degree of renal toxicity. In addition, we identified two potential biomarkers that may predict early renal toxicity. This data may contribute to elucidate of the genetic events during early renal injury and to discover the potential biomarkers for nephrotoxicity induced by gentamicin.

Application of Multivariate Statistics and Geostatistical Techniques to Identify the Distribution Modes of the Co, Ni, As and Au-Ag ore in the Bou Azzer-East Deposits (Central Anti-Atlas Morocco)

  • Souiri, Muhammad;Aissa, Mohamed;Gois, Joaquim;Oulgour, Rachid;Mezougane, Hafid;El Azmi, Mohammed;Moussaid, Azizi
    • Economic and Environmental Geology
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    • v.53 no.4
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    • pp.363-381
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    • 2020
  • The polymetallic Co, Ni, Cu, As, Au, and Ag deposits of Bou Azzer East are located in the western part of the Bou Azzer inlier in the Central Anti Atlas, Morocco. Six stages of emplacement of the mineralization have been identified. Precious metals (native gold and electrum) are present in all stages of this deposit except the early nickeliferous stage. From the Statistical analysis of the Co, As, Ni, Au, and Ag contents of a set of 501 samples, shows that the Pearson correlation coefficient between As-Co elements (0.966) is the highest followed by that of the Au-Ag couple (0.506). Principal component analysis (PCA) and hierarchical ascending classification (HAC) of the grades show, that Ni is associated with the pair (As-Co) and Cu is rather related to the pair (Au-Ag). The kriging maps show that the highest values of the Co, As and Ni appear in the contact of the serpentinite with other facies, as for those of Au and Ag, in addition to anomalous zones concordant with those of Co, Ni and As, they show anomalies at the extreme South and North of the study area. The development of the anomalous Au and Ag zones is mainly along the N40-50°E and N145°E directions.

Study on Sensory Characteristics and Consumer Acceptance of Commercial Soy-meat Products (콩고기의 관능적 특성 및 소비자 기호도 분석)

  • Kim, Mi Ra;Yang, Jeong-Eun;Chung, Lana
    • Journal of the Korean Society of Food Culture
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    • v.32 no.2
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    • pp.150-161
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    • 2017
  • This study was conducted to identify sensory characteristics of soy-meat samples by trained panels and to observe the relationship between these sensory characteristics and consumer acceptability of the samples. Descriptive analysis was performed on eight samples; four types of patty style soy-meat samples (Soy-meat Patty; SP) made with a Ddukgalbi recipe (YSP, VSP, LSP, and SSP) and four types of Bulgogi style soy-meat samples (Soy-meat Bulgogi; SB) made with a Bulgogi recipe (YSB, VSB, LSB, and SSB). Seven panelists were trained, and they evaluated the appearance, odor/aroma, flavor/taste, texture/mouth feel, and after taste attributes of these samples. Forty attributes were generated by panelists, and 37 attributes were significantly different across products (p<0.05). The SB group was characterized by beef, leek, and garlic flavor as well a sweetness, denseness, slipperiness, chewiness, and pepper after taste. The SP group was characterized by roughness, particle size, rancid oil flavor, raw bean flavor, astringent, sourness, and adhesiveness. Consumer test (n=125) showed that the VSB sample had the highest scores for acceptability of appearance, flavor, texture, and overall liking. The PLSR results show that the attributes that were more positively associated with acceptance of soy-meat samples were beef taste, wetness, and chewiness, whereas the raw bean smell and rancid oil flavor attributes were negative.

Sensory Properties and Consumer Acceptance of Dasik (Korean Traditional Confectioneries) (다식의 관능적 특성 및 소비자 기호도 분석)

  • Yang, Jeong-Eun;Lee, Ji-Hyeon;Choi, Soon-Ah;Chung, Lana
    • Journal of the East Asian Society of Dietary Life
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    • v.22 no.6
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    • pp.836-850
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    • 2012
  • This study was conducted to identify the sensory characteristics of the Korean traditional confectionery, dasik, prepared under different conditions and to compare their consumer acceptance in Korea. To accomplish this, descriptive analysis of eight samples prepared using two types of rice cake powder, dasik (Rflour, Rflour_Omija), brown rice powder red ginseng dasik (Brice_Ginseng_P), pinepollen dasik (PineP), black sesame dasik (BSesame), bean dasik (Rbean), and two types of mungbean starch dasik (Starch_Omija, Starch_Greentea), was conducted by ten trained panelists. In addition, 81 consumers evaluated the overall acceptance (OL), acceptance of appearance (APPL), odor (ODL), flavor (FLL), and texture (TXTL) of the samples using a 9-point hedonic scale, as well as the perceived intensities of sesame flavor, sweetness, and hardness using a 9-point just-about-right (JAR) scale. Partial least square- regression (PLSR) indicated that the BSesame and Rbean samples, which had significantly (p<0.05) high roasted sesame, burnt, greasy, glossy, and cooked chestnut flavor scores, had the highest acceptability and consumer desire scores. Additionally, the PineP and Rflour_Omija samples, which had relatively high particle size, transparency, roughness, spoiled tofu, fermentation and raw rice flavor scores, were the least preferred samples. Therefore, roasted sesame, burnt, greasy, glossy, and cooked chestnut flavor attributes were considered drivers of "liking" whereas particle size, transparent, roughness, spoiled tofu, fermentation, and raw rice flavor attributes acted as drivers of "disliking" among consumers.

Comparisons of Flora and Vegetation Distribution in Main and Abandoned Channels (본류와 폐천의 식물상과 식생분포의 비교)

  • Cho, Hyung-Jin;Hong, Il;Yeo, Hong-Koo;Cho, Kang-Hyun
    • Journal of Wetlands Research
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    • v.11 no.1
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    • pp.65-73
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    • 2009
  • We investigated characteristics of channel morphology, flora and vegetation distribution at the main and the abandoned channels of the Hwangguji Stream and the Cheongmi Stream. The analysis of aerial photographs and old topographical maps showed that the abandoned channels were made by cut-off from the main channel due to the construction of artificial levee. The total number of species and percentage of exotic plants at the main channels were higher than those at the abandoned channels. At the abandoned channel, the percentage of species number of hydrophytes and hygrophytes was higher than those at the main channels in the both stream. The results of principal component analysis (PCA) showed that the floral structure between at the main and the abandoned channel was more similar in the Hwangguji Stream than that in the Cheongmi Stream. The relative distribution areas of hydrophytes and hygrophytes at two abandoned channels were much higher than those at the main channels in the both stream. The dominant plant was an emergent macrophyte, Zizania latifolia at two abandoned channels. Therefore, flora and vegetation at the abandoned channel showed more hydric and lentic characteristics and provided diversity on the landscape level.

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Real-time Fault Diagnosis of Induction Motor Using Clustering and Radial Basis Function (클러스터링과 방사기저함수 네트워크를 이용한 실시간 유도전동기 고장진단)

  • Park, Jang-Hwan;Lee, Dae-Jong;Chun, Myung-Geun
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.20 no.6
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    • pp.55-62
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    • 2006
  • For the fault diagnosis of three-phase induction motors, we construct a experimental unit and then develop a diagnosis algorithm based on pattern recognition. The experimental unit consists of machinery module for induction motor drive and data acquisition module to obtain the fault signal. As the first step for diagnosis procedure, preprocessing is performed to make the acquired current simplified and normalized. To simplify the data, three-phase current is transformed into the magnitude of Concordia vector. As the next step, feature extraction is performed by kernel principal component analysis(KPCA) and linear discriminant analysis(LDA). Finally, we used the classifier based on radial basis function(RBF) network. To show the effectiveness, the proposed diagnostic system has been intensively tested with the various data acquired under different electrical and mechanical faults with varying load.