• 제목/요약/키워드: PB

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원화추출물(PB-81)의 소 로타바이러스 설사병에 대한 항바이러스 및 치료효과 (Antiviral and Therapeutic Effects of Extracts (PB-81) of Daphne Genkwa (Siebold & Zucc.) on Bovine Rotavirus)

  • 이미영;김연성;박재명;송재찬
    • 생명과학회지
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    • 제34권6호
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    • pp.408-417
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    • 2024
  • 원화(Daphne genkwa (Siebold & Zucc))의 50% 에탄올 추출물인 PB-81이 소 로타바이러스 설사병 환축에서 설사병의 치료효과와 바이러스 증식 억제 효과가 나타나는가를 확인하였다. PB-81에 의해 상피세포주인 A549 세포와 혈액세포주인 NK92 세포에서 각각 IFN-β와 IFN-γ가 유도되는 것을 확인하였다. PB-81의 바이러스의 증식억제 효과를 확인하기 위해 PB-81을 MBDK 세포에 바이러스의 감염 전, 동시, 감염 후에 투여하는 세 가지 경우에서 바이러스 억제효과를 확인한 결과 PB-81을 투여한 모든 경우에서 바이러스가 억제되었으며, 바이러스 감염 전에서 투여하는 경우에서 가장 좋은 바이러스 억제효과가 나타났다. 마우스에서의 독성검사에서는 투여최대용량인 20 mg/mL에서도 독성에 따른 부작용이 나타나지 않았다. 소 로타바이러스 설사병 환축 16두와 대조군 4두를 대상으로 한 치료효과 검증에는 20 mg/5 mL 용량의 PB-81을 투여한 결과, PB-81을 투여한 모든 소 로타바이러스 설사병 환축이 완치되었으며 PB-81의 투여 후에 완치까지 소요된 기간은 PB-81투여군이 평균 2.25일이었고, PB-81을 투여하지 않은 대조군이 6.5일로 PB-81의 투여에 의한 소 로타바이러스 설사병의 치료효과가 나타나는 것을 확인하였으며 PB-81을 투여한 모든 환축에서 부작용이 검출되지 않았다.

식물의 납과 아연의 내성에 관한 유전현상 (Genetic phenomena for the pb and zu tolerance in plants)

  • Yun, Jeoung-Ok;Lee, In-Sook
    • The Korean Journal of Ecology
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    • 제15권2호
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    • pp.173-180
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    • 1992
  • Pb, Zn tolerance of phaseolus multiflorus was investigated, based on the elongation of root and stem, pollen Germination and progeny quality in various pb, zn concentrations. The result obtained by water culture showed that the growth of roots and steams of phaseolus multiflorus from pb-zn mine site is less inhivited than that of the control site. The flower of phaseolus multiflorus from which pollen was taken were grown without added pb, zn and percent germination of pollen observed in a range of pb, zn concentrations. The percent germination of pollen from pb-zn mine site was higher than the control site. phaseolus multiflorus collected at a pb-zn mine site and the control site was site were grown at different pb, zn concentrations, its progeny was retreated with same concentrations of pb-zn mine site was more vigorous than the control site. thus, pb-zn tolerance was able to expressed in both pollen and sporophytes.

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熔融 Pb-Bi, Pb-Na, Bi-Na 및 Pb-Bi-Na 系의 物理化學的硏究 (Thermodynamic Study of Liquid Pb-Bi, Pb-Na, Bi-Na Binaries and Pb-Bi-Na Ternary Solutions)

  • 고창식
    • 대한화학회지
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    • 제6권2호
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    • pp.133-142
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    • 1962
  • This study was carried out to investigate the lead-bismuth-sodium ternary system which a basis of the Dittmer method as a part of "the fundamental study of pyrometallurgical debismuthizing of lead". Thermodynamic properties of each liquid Pb-Bi, Pb-Na binaries as well as liquid Pb-Bi-Na ternary solution were measured by e.m.f. of these concentration cells, and those of each component were also determined. Furthermore, iso-activity lines including Pb rich side composition of Pb-Bi-Na ternary solution were determined. The relationship between those thermodynamic characteristics and tendency of intermetallic compound formation was discussed through the above experiments.

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$Pb(Mg_{1/3}Nb_{2/3})O_3-PbZrO_3$계 요업체의 전계 유기변위와 분극특성 (Field-induced Strains and Polarization Switching Mechanisms in $Pb(Mg_{1/3}Nb_{2/3})O_3-PbZrO_3$ Ceramics)

  • 김명철
    • 한국세라믹학회지
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    • 제34권6호
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    • pp.569-576
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    • 1997
  • Electrically-induced strain and polarization studies of the (1-x)Pb(Mg1/3Nb2/3)O3-PbZrO3 crystalline solutions have been done. Dielectric constants with temperature were investigated for 0$\leq$x$\leq$0.95. With increasing PbZrO3 content the transition maxima were found to move to higher temperature region and DPT (Diffused Phase Transition) properties were decreased for x$\leq$0.60. Phase transition between ferroelectric states and antiferroelectric states was confirmed for 0.93$\times$10-3 for 0.4

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해조류를 이용한 Pb 및 Cu의 흡착 (Biosorption of Pb and Cu by Marine Algae)

  • 서근학;안갑환;조문철;김병진;진형주;홍용기
    • KSBB Journal
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    • 제13권4호
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    • pp.444-448
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    • 1998
  • Biosorption of Pb and Cu was evaluated for 23 species of marine algae collected from a Korean coast. Among a variety of species for biosorbent potential, Hypnea charoides showed the highest capacity for Pb. An adsorption equilibrium was reached in about 2 hr for Pb and 30 min for Cu. The uptake capacity was 192.8 mg Pb/g biomass and 256 mg Cu/g biomass, respectively. The adsorption parameters for Pb and Cu were determined according to Langmuir model. With an increase in pH value, more negative sites are becoming avaliable for adsorption of pH and Cu, thus the removal of Pb and Cu increases at alkaline conditions. The selectivity of mixture solution shows the uptake order of Pb>Cu>Cr>Cd. When Ca concentration increases in Pb solution, Pb was selectively adsorbed.

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Preparation of Ultrafine Au-Pb Particles by Gas-evaporation Technique

  • Ohno, Takehisa;Funaguchi, Hironori
    • 한국분말야금학회:학술대회논문집
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    • 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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    • pp.158-159
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    • 2006
  • Ultrafine Au-Pb particles prepared by two method, (1) simultaneous evaporation of Au and Pb in inert gas and (2) subsequent vapor condensation of Pb in a differentially evacuated tube onto flying Au nanoparticles prepared by gasevaporation technique, were observed by electron microscopy. In the method (1), the particles that grew at the region where the two smoke masses converged, consisted of alloy phases. In the method (2), the particles consisted of two or three phases of Au, $Au_2Pb$, $AuPb_2$ and Pb phases in turn from the inner part, Pb-rich particles being composed of only two phases of $AuPb_2$ and Pb.

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C-Metylcalix[4]resorcinarene에서 Pb(II)와 Cr(III)의 흡착 특징 (Adsorption Characteristics of Pb(II) and Cr(III) onto C-Methylcalix[4]resorcinarene)

  • Jumina, Jumina;Sarjono, Ratnaningsih Eko;Siswanta, Dwi;Santosa, Sri Juari;Ohto, Keisuke
    • 대한화학회지
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    • 제55권3호
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    • pp.454-462
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    • 2011
  • C-Metylcalix[4]resorcinarene(CMCR)에서 Pb(II)와 Cr(III)의 흡착 특징에 대한 연구는 수행되어왔다. CMCR은 resorcinol, acetaldehyde 그리고 HCl로 부터 1단계 합성으로 만들어졌다. 일괄처리시스템에서 대부분의 변수는 CMCR이 Pb(II)와 Cr(III)에 대해 좋은 흡착제라는 것을 확인했다. Cr(III)은 Pb(II)보다 더 크게 흡착되지만 Cr(III)의 흡착속도는 Pb(II) 보다 더 느리다. Pb(II)와 Cr(III) 흡착의 흡착운동에너지는 batch안에서 유사 2차 운동 모델을 따른다. 그러나 고정상 컬럼 시스템에서 Pb(II)의 운동에너지는 일차 모델을 따른다. 흡착된 Pb(II)을 되찾기 위한 탈착 연구는 증류수와 HCl을 가지고 순차적으로 수행되었다. 그리고 그 결과는 흡착은 화학흡착에 의해 지배된다는 것을 보여주었다.

A longitudinal study of the relation of lead in blood to lead in air concentrations among battery workers

  • Hodgkins Douglas G.;Robins Thomas G.;Hinkamp David L.;Schork M. Anthony;Krebs William H.
    • 대한예방의학회:학술대회논문집
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    • 대한예방의학회 1994년도 교수 연수회(환경)
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    • pp.577-584
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    • 1994
  • The relation between lead in air (PbA) and lead in blood (PbB), concentrations was investigated among 44 workers in five major operations in a United States high volume, lead acid battery plant. The study covered a 30 month period in which workers received frequent PbA and PbB determinations, workers remained in a single job, and PbA concentrations averaged below the US Occupational Safety and Health Administration (OSHA) permissible exposure limit of $50{\mu}g/m^{3}$. In both univariate and multivariable linear regressions, longitudinal analyses averaging PbA concentrations over the 30 month study period appeared superior to cross sectional analyses using only six month PbA averages .to model PbB concentrations. The covariate adjusted coefficient ($\alpha$ value) for PbA($\mu/m^{3}$) in models of PbB (${\mu}g/100\;g$) was 1-14. This figure is strikingly higher than that reported in previous studies in the lead acid battery industry in all of which PbA concentrations were substantially higher than in the current study. Plausible explanations for the differences in a: values include non-linearity of the PbA-PbB curve, a higher fraction of large size particulate associated with higher PbA concentrations, survivor bias among workers exposed to higher PbA concentrations, and the cross sectional designs of most previous studies. Despite previously reported problems with the model used by OSHA to predict PbA-PbB relations, the findings of this study are in good agreement with the predictions of that model.

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활성슬러지를 이용한 납 이온 제거에 영향을 미치는 인자에 대한 연구 (A Study on the Factors Affecting Pb^{2+}$ Removal by Activated Sludge)

  • 김동석;김미경;서정호
    • 한국환경과학회지
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    • 제7권4호
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    • pp.559-564
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    • 1998
  • The effects of temperature, initial $Pb^{2+}$concentration and initial sludge concentration on the initial $Pb^{2+}$ removal rate and maximal $Pb^{2+}$removal amounts in activated sludge, respectively, were investigated. The removal of $Pb^{2+}$ in activated sludge was proved to be temperature-dependent process. The initial $Pb^{2+}$ removal rate increased from 187.5 to 261.4 mg $Pb^{2+}$/g sludge dry weight min, in response to the promoted temperature from 1$0^{\circ}C$ to 6$0^{\circ}C$, while the maximal $Pb^{2+}$removal amount (78.5 mg $Pb^{2+}$/g sludge dry weight) occurred at 30t . As the initial $Pb^{2+}$concentration increased from 36 to 228 mg $Pb^{2+}$/L at the constant temperature of 30C and initial sludge concentration of 1.5 g sludge dry weight/L, the time to reach an equilibrium state was almost independent of the initial $Pb^{2+}$concentration and the equilibrium $Pb^{2+}$/removal amount was increased Irom 41.9 to 73.6 mg $Pb^{2+}$/g sludge dry weight. On the contrary, the equilbrium $Pb^{2+}$ emoval amount was decreased from 87.7 to 65.3 mg $Pb^{2+}$/g sludge dry weight as the in- crease of initial sludge concentration from 0.22 to 1.76 g sludge dry weight/L.

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207Pb nuclear magnetic resonance study in PbWO4:Mn2+ and PbWO4:Dy3+ single crystals

  • Yeom, Tae Ho
    • 한국자기공명학회논문지
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    • 제22권4호
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    • pp.107-114
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    • 2018
  • In this exploration, the nuclear magnetic resonance of the $^{207}Pb$ nucleus in $PbWO_4:Mn^{2+}$ and $PbWO_4:Dy^{3+}$ Single Crystals using FT-NMR spectrometer is investigated. The line width of the resonance line for the $^{207}Pb$ nucleus decreases as temperature increases due to motional narrowing. The chemical shift of $^{207}Pb$ NMR spectra also increases as temperature decreases for both crystals. The spinlattice relaxation times $T_1$ of $^{39}K$ nucleus were calculated as a function of temperature (180 K~400 K). The $T_1$ of $^{207}Pb$ nucleus decreases as temperature increases. The dominant relaxation mechanism at the studied temperature range can be deduced as the Raman process, which is the coupling between lattice vibrations and the nuclear spins. This deduction is substantiated by the fact that the nuclear spin-lattice relaxation rate $1/T_1$ of the $^{207}Pb$ nucleus in $PbWO_4:Mn^{2+}$ and $PbWO_4:Dy^{3+}$ single crystal is proportional to $T^2$, or temperature squared. The activation energies for the $^{207}Pb$ nucleus in $PbWO_4:Mn^{2+}$ and $PbWO_4:Dy^{3+}$ single crystals are $E_a=49{\pm}1meV$ and $E_a=47{\pm}2meV$, respectively.