• Journal of the Korean Society for Precision Engineering
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• v.16 no.10
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• pp.187-193
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• 1999

Dimensional difference by welding deformation is usually occurred at steel bridge manufacturting or multi-pass welding used at joining of thick plates. Be this, root gap out of standard is frequently developed at butt weld joints. For example, although standard root gap below 6mm at butt weld joints of plates under 15mm thickness, maximum 30mm root opening is developed at the weld field. At this case, 24mm parts out of standard is generally built up. But, there are no accumulated data and restriction about this built up welding pars. In this study, therefore, the accumulation of data for built up parts and the verification of the mechanical properties of weld part as root gap is performed. It is included that tensile, bending, impact, hardness test and microstructural review for each welding specimen of 0mm, 6mm, 30mm root opening.

• Proceedings of the Korean Society of Toxicology Conference
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• 2001.10a
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• pp.164-164
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• 2001

Manganese (Mn) intoxication causes a parkinsonian syndrome. It may be difficult to distinguish Mn-induced parkinsonism from idiopathic Parkinson disease (IPD). Neuropathological descriptions on the brains with Mn intoxication showed the preferential damage in the globus pallidus and substantia nigra pars reticularis.(omitted)

• Korean Journal of Veterinary Pathology
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• v.5 no.1
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• pp.17-20
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• 2001

We examined the stomaches of slaughtered pigs to evaluate the gastric lesions. Gastric ulcer accompanying parakeratosis and hyperkeratosis were most frequently observed in the mucosa layer of pars oesophagea. Diffuse congestion and focal necrosis was also frequently seen on the fundus. Pierce wounds by toothpick were seen from 3 stomaches.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.882-885
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• 2011

This paper presents testing and self-calibration of RF circuits using MEMS switches to identify process-related defects and out of specification circuits. We have developed a novel multi-tone dither test technique where the test stimulus is generated by modulating the RF carrier signal with a multi-tone signal generated using an Arbitrary Waveform Generator (AWG) with additive white Gaussian noise. This test stimulus is provided as input to the RF circuit and peak-to-average ratio (PAR) is measured at the output. For a faulty circuit, a significant difference is observed in the value of PAR as compared to a fault-free circuit. Simulation is performed for various circuit conditions such as fault-free as well as fault-induced and their corresponding PARs are stored in the look-up table. This testing and self-calibration technique is exhaustive and efficient for present-day communication systems.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.11b
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• pp.192-192
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• 2002

Hospital waste incinerating workers are exposed to various pyrolysis products including polycyclic aromatic hydrocarbons (PARs). We evaluated their exposure by assessing urinary 1-hydroxypyrene glucuronide (1-OHPG), as internal dose of PAH exposure. The potential effect of genetic polymorphisms of GSTM1/T1 involved in PAH metabolisms was also investigated.(omitted)

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.824-827
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• 2005

This paper represents a study on disassembly sequence generation for automobile parts. This is particularly useful because adequate end-of-life disassembly becomes crucial as take-back obligations are imposed for environmental reasons. Therefore in this paper a method is suggested to automatically derive all the feasible subassemblies and feasible actions between them from the assembly modeling files. As a result, in consideration of the all pars and subassemblies the optimum disassembly sequence is generated. And the optimum disassembly sequence for a certain part or subassembly can be also generated.

• Molecules and Cells
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• v.38 no.8
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• pp.734-740
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• 2015

Recent studies report that a history of antidepressant use is strongly correlated with the occurrence of Parkinson' disease (PD). However, it remains unclear whether antidepressant use can be a causative factor for PD. In the present study, we examined whether tricyclic antidepressants amitriptyline and desipramine can induce dopaminergic cell damage, both in vitro and in vivo. We found that amitriptyline and desipramine induced mitochondria-mediated neurotoxicity and oxidative stress in SH-SY5Y cells. When injected into mice on a subchronic schedule, amitriptyline induced movement deficits in the pole test, which is known to detect nigrostriatal dysfunction. In addition, the number of tyrosine hydroxylase-positive neurons in the substantia nigra pars compacta was reduced in amitriptyline-injected mice. Our results suggest that amitriptyline and desipramine may induce PD-associated neurotoxicity.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 1999.04a
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• pp.24-24
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• 1999

This study addresses the effectiveness of TEC(Thermoelectric cooler) application for spacecraft thermal control. The required radiator area and power consumption characteristics of active thermal control using TEC are compared with the passive control at BOL and EOL through unsteady thermal analyses by calculating external heat fluxes. When the component operating temperature is low enough in TEC active control, the required radiator area can be smaller than the passive thermal control. TEC also needs less power consumption than the passive control under the condition that the temperature of cooling pars is low enough and/or the design temperature margin of the components is narrow enough.

• Journal of Preventive Medicine and Public Health
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• v.46 no.6
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• pp.319-328
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• 2013

Objectives: This study estimated the association of cardiovascular health behaviors with the risk of all-cause and cardiovascular disease (CVD) mortality in middle-aged men in Korea. Methods: In total, 12 538 men aged 40 to 59 years were enrolled in 1993 and followed up through 2011. Cardiovascular health metrics defined the following lifestyle behaviors proposed by the American Heart Association: smoking, physical activity, body mass index, diet habit score, total cholesterol, blood pressure, and fasting blood glucose. The cardiovascular health metrics score was calculated as a single categorical variable, by assigning 1 point to each ideal healthy behavior. A Cox proportional hazards regression model was used to estimate the hazard ratio of cardiovascular health behavior. Population attributable risks (PARs) were calculated from the significant cardiovascular health metrics. Results: There were 1054 total and 171 CVD deaths over 230 690 person-years of follow-up. The prevalence of meeting all 7 cardiovascular health metrics was 0.67%. Current smoking, elevated blood pressure, and high fasting blood glucose were significantly associated with all-cause and CVD mortality. The adjusted PARs for the 3 significant metrics combined were 35.2% (95% confidence interval [CI], 21.7 to 47.4) and 52.8% (95% CI, 22.0 to 74.0) for all-cause and CVD mortality, respectively. The adjusted hazard ratios of the groups with a 6-7 vs. 0-2 cardiovascular health metrics score were 0.42 (95% CI, 0.31 to 0.59) for all-cause mortality and 0.10 (95% CI, 0.03 to 0.29) for CVD mortality. Conclusions: Among cardiovascular health behaviors, not smoking, normal blood pressure, and recommended fasting blood glucose levels were associated with reduced risks of all-cause and CVD mortality. Meeting a greater number of cardiovascular health metrics was associated with a lower risk of all-cause and CVD mortality.

• The Korean Journal of Zoology
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• v.39 no.4
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• pp.337-351
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• 1996

Melatonin Is a multifunctional hormone secreted from the pineal gland in the middle of cerebrum and cerebellum. Its synthesis and release reflect photopedod;Photopedod is a yearly predictable ambient factor that most animals utilize as an environmental cue for maximum survival. Hamsters maintaln reproductive activity in summer during which day length exceeds night time. Upon the advent of autumnal equinox they undergo gonadal regression. The photoperiodic effects are prevented by removal of the pineal gland and restored by the timed repiacument of melatonin. The results suggest that melatonin constitutes part of control mechanism whereby environmental information is transduced to neuroendocrine signal responsIble for the functional integrity of the reproductive system. From the studies for the action site of melatonin following the treatment of photopedod or melatonin in the lesion of a spedflc portion of hypothalamus, suprachiasmatic nuclei and pars tuberalis are shown to be a consensus site for melatonIn. The action of melatonin. In the regulation of reproduction is largely unknown. It is mainly due to the lack of acute effect of melatonin on gonadotropin secretion. However, reduction of the gonadotropln release and augmentation of the hypothalamic gonadotropin-releasing hormone (GnRH) content by long-term treatment of melatonln Indicate that constant presence of melatonln may partidpate in the regulation of sexual activity via the GnRH neuronal system. The action mechanism by which melatonin exerts Its effect on GnRH neuron needs to be eluddated. The inability of opiold analogues to affect the reproductive hormones in sexually regressed animals by inhibftory photopedod and melatonin suggests that the opioldergic neuron may be a prime intervening mediator. Recent cloning of melatonin receptor will contribute to investigate its anatomical Identification and the action mechanism of melatonin on target tissues at the molecular level.