• Journal of the Korea Convergence Society
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• v.10 no.4
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• pp.277-284
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• 2019

Purpose: The purpose of this study is to examine the relationships among job stress, resilience and turn over intention of new graduate nurses in general hospital. Methods: A descriptive regression design was used and the participants were 90 new graduate nurses from one general hospital in S city. Data analysis included t-test, ANOVA, pearson's correlation and multiple regression. Results: There were significant correlations between conflict with physicians(r=.17, p=.049), problem relating to supervisors(r=.18, p=.040), discrimination(r=.18, p=.041), resilience(r=-.21, p=.023) and turnover intention. The regression model explained approximately 24.5 % of turnover intention. Conclusion: The findings suggest that nursing leaders have to reduce job stress and to improve resilience of new graduate nurses.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.374-382
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• 2018

The aim of this study was to identify how information media about patient safety incidents influences nursing students' knowledge, perception, and confidence in performance toward patient safety. A total of 337 nursing students agreed to participate in this study. Data were collected from the participants between June 4 and June 12, 2018. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, and Pearson's correlation coefficient with SPSS 21.0. Participants' scores for knowledge, perception, and performance confidence toward patient safety were $6.43{\pm}1.92$, $41.02{\pm}4.35$, and $39.61{\pm}5.89$, respectively. Patient safety knowledge was significantly different according to age, grade, and patient safety education experience. Patient safety perception was significantly different according to satisfaction with the major, patient safety performance confidence showed statistically significant differences according to grade, patient safety education experience, and major satisfaction. Information media exposure to patient safety incidents on TV and knowledge (r=.32, p<.000) and performance confidence (r=.21, p<.000) toward patient safety had positive correlations. Information media exposure to patient safety incidents on the internet and knowledge (r=.34, p<.000), perception (r=.12, p=.028), and performance confidence (r=.24, p<.000) toward patient safety also had positive correlations. This study provides basic data for nursing education and program development for patient safety management.

• Child Health Nursing Research
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• v.6 no.2
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• pp.132-143
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• 2000

The purpose of this correlational study was to find the correlation between the infant temperament, mother-infant interaction, and child-rearing environment. The subjects of this study were 37 dyads of healthy mothers and healthy infants. Data were collected from 15th of March to 3rd of September, 1999. Convenient sampling was done at Obstetric wards of one University hospital, and demographic data were collected before discharge. At one month and three month postpartum, we visited subject's home, and collected the data on the infant temperament, and also video taped the mother-infant interaction during feeding. In addition, child-rearing environment was checked by researcher according to HOME(Home Observation for Measurement of the Environment) at three months postpartum. Mother-infant interactions were rated according to the NCAST Feeding Scale later. Data were analyzed by window SPSS program, and correlations between the infant temperament, mother-infant interaction, and child-rearing environment were analyzed by Pearson's correlational coefficient. The results were as follows: 1. Infant temperament. 1) Among the subscales of infant temperament, mothers perceived cuddliness and amenability most positively at one month, and responsivity and amenability most positively at three months. 2) In subscale analysis of stability, amenability, responsivity, and persistence were stable with the time. 3) Significant relationships were found between the malleability and amenability, between the malleability and responsivity at one month, and also between the malleability and amenability, and between the malleability and cuddliness at three months. 2. Correlations of infant temperament and mother-infant interaction. 1) There was no significant relationship between the infant temperament and mother-infant interaction at one month. 2) There was a significant relationship between the infant temperament and mother-infant interaction at three months(r=.335, p<.05). In subscale analysis, there were significnt relationships between the total score of infant temperament and maternal sensitivity to infant's cues(r=.372, p<.05), and between the total score of infant temperament and maternal response to infant's distress (r=.331, p<.05). 3. Correlations of infant temperament and child-rearing environment. 1) There was no significant relationship between the total score of infant temperament at one month and total score of HOME at three months. In subscal analysis, the total score of infant temperament at one showed significant relationships with the organization of environment(r=.413, p<.05), and the emotional, verbal response at three months(r=.337, p<.05). 2) There was a significant relationship between the total score of infant temperament at three months and the total score of HOME at three months (r=.599, p<.01). In subscal analysis, the total score of infant temperament at three months showed significant relationships with the organization of environment(r=.410, p<.05), maternal involvement(r=.482, p,.01), and the emotional, verbal response(r=.695, p<.01) at three months. 4. Correlations of mother-infant interaction and child-rearing environment. There was a significant relationship between the maternal score of mother-infant interaction at one month and three months and the total score of HOME at three months (r=.474, p<.01; r=.452, p<.01). In conclusion, it was proved that infant temperament had significant relationships with mother-infant interaction and child-rearing environment, especially when the infants were getting older. This showed the possibility for changeability of infant teperament by the maternal factors.

• Journal of Korean Academy of Nursing
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• v.34 no.2
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• pp.270-277
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• 2004

Purpose: The purpose of this study was to investigate the relationship between decision-making factors(theoretical knowledge, expertise, empowerment, intuition) and participation in proportion to nurses's clinical experience. Method: Data was collected by quota sampling from July 10, 2001 to August 22, 2001 from 132 clinical nurses who work for 3 General hospitals. Data was analyzed using SPSSWIN 10.0 with crosstab, ANOVA, and stepwise multiple regression. Result: Expertise(F=34.347, p=.000), empowerment(F=29.316, p=.000), and participation(F=3.276, p=.041) were significantly different among 3 clinical experience groups. Clinical experience correlated with expertise(r=.551, p=.000) and empowerment(r=.492, p=.000), and Decision-making participation also correlated with expertise(r=.351, p=.000) and empowerment(r=.265, p=.002). Decision-making participation is effected by theoretical knowledge(under 3.00yr clinical experience), expertise(3.01-5.00yr), and empowerment(above 5.01yr). Conclusion: These findings indicate that factors(theoretical knowledge, expertise, or empowerment) on decision-making participation varies as nurses's clinical experience differs. Therefore, decision-making needs bilateral agreement between staff nurses and nurse managers rather than the responsibility of one.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7081-7084
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• 2013

MicroRNAs have been demonstrated to regulate proliferation and apoptosis in many types of cancers, but biological functions in osteosarcomas remain relatively unknown. Here, we found expression of miR-802 to be up-regulated in osteosarcoma tissues in comparison with adjacent normal tissues. Enforced expression of miR-802 was able to promote cell proliferation in U2OS and MG63 cells, while miR-802 antisense oligonucleotides (antisense miR-802) inhibited cell proliferation. At the molecular level, our results further revealed that expression of p27, a negative cell-cycle regulator, was negatively regulated by miR-802. Therefore, the data reported here indicate that miR-802 is an important regulator in osteosarcoma, our findings contributing to a better understanding of important mis-regulated miRNAs in this tumour type.

• Korean Parent-Child Health Journal
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• v.2
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• pp.83-110
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• 1999

The purpose of this study was to identify the sleep/activity patterns of neonates and to provide a baseline data for the development effective mother-infant relationship. Subjects of this study were 36 newborns aged 1-21 days and stayed in Postpartum Care Center in Taejon during the period of October 28th, 1999 to February 10th, 2000. The data were collected using NCASA developed by Barnard et al. and were analyzed with SPSS 7.5 for window program. The results of this study were as follows: 1. An average day sleep of neonates was 8.0 hours, night sleep was 3.6 hours, and total sleep was 11.6 hours. A longest period of day sleep was 3.8 hours and a longest period of night sleep was 3.4 hours. The regularity of day sleep was 22.1%, night sleep was 23.3%, and total was 22.1%. 2. The frequency of daytime feeding was 6.9, nighttime fee ding was 3.4, resulting in total of 10.3. The regularity of feeding was 37.4%, and the frequency of night awakening was 2.4. 3. Associations among variables related to neonate's sleep/activity records were as follows : - The regularity of total sleep was positively correlated with the frequencies of day sleep(r=.57, P=.00), night sleep (r=.40, P=.01), and total sleep(r=.65, P=.00). - The frequency of total feeding was negatively correlated with the frequencies of day sleep(r=-.29, P=.04), night sleep(r=-.39, P=.02), and total sleep(r=-.42, P=.00), as well as longest day sleep(r=-.50, P=.00). - The regularity of feeding was negatively correlated with the frequency of night sleep(r=-.35, P=.02), longest period of day sleep(r=-.32, P=.04), and longest period of night sleep(r=-.30. P=.04), whereas positively correlated with frequencies of daytime feeding (r=.29, P=.02) and nighttime feeding (r=.32, P=.05). - The frequency of night awakening was negatively correlated with amount of night sleep(r=-.39, P=.02) and frequency of daytime feeding(r=-.42, P=.01) while positively correlated with frequencies of nighttime feeding(r=.68, P=.00) and total feeding(r=.50, P=.00). 4. Although there was no statistical significant difference between sleep pattern and infant's age, following tendency was noted: - As baby gets older, total amount of sleep and longest period of day sleep decreased while longest period of night sleep increased. - As baby gets older, the regularity of day sleep decreased while the regularity of night sleep and total sleep slightly increased. - The frequencies of daytime and total feedings increased while the frequency of nighttime feeding decreased. In conclusion, the author found that the neonates of this study showed less amount of sleep, more night awakening, and more night time feedings than NCAST sample. There was a certain sleep/activity pattern existed: If babies were fed more frequently, daytime or nighttime sleeping hours became shorter, and if babies had longer daytime sleep, frequent nighttime awakenings were noted. This pattern illustrated the significant influence of feeding and sleep periods on each other. Awakening in the night is natural and normal patterns in the newborn period. The result of this study will provide information to parents about what to expect their infants.

• The Korean Journal of Zoology
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• v.6 no.2
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• pp.11-15
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• 1963

A total of 220 adult male mice (18-20g) of the S.M. strain were divided into ten experimental and control groups. The total-body X-ray irradiation doses used were 50 r, 100r, 200r, 400r, 600r, 800r, 1,000r, 1,200r, 1,400r, and1,600r. The respiratory arrest (mortality) caused by each irradiation doses were observed for 30 days. Relationships between irradiation doses and survival time and percentage of response were examined. From this experiment, a formula was obtained to express the relationship among three factors, which may be presented as follows : {{{{{{{{P= { 10} over { SQRT { 2 pi } } INT _{ - INF }^{ p'} e-{(p'-50)^2 } over {200 }dp···(a) p'=100 LEFT { t^0.3- LEFT ( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } } / LEFT { LEFT ( { 26372.43} over {D-81.86 } RIGHT ) ^{ { 1} over {2.5 } } -( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } ···(b) p= { (D-60) t^0.75-16.9965} over {0.2186 t^0.75 +263.55434 }····(c) }} {{{{P= { 10} over { SQRT { 2 pi } } INT _{ - INF }^{ p'} e-{(p'-50)^2 } over {200 }dp···(a) p'=100 LEFT { t^0.3- LEFT ( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } } / LEFT { LEFT ( { 26372.43} over {D-81.86 } RIGHT ) ^{ { 1} over {2.5 } } -( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } ···(b) p= { (D-60) t^0.75-16.9965} over {0.2186 t^0.75 +263.55434 }····(c)

• BMB Reports
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• v.55 no.2
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• pp.104-109
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• 2022

Skeletal myogenesis is essential to keep muscle mass and integrity, and impaired myogenesis is closely related to the etiology of muscle wasting. Recently, miR-141-3p has been shown to be induced under various conditions associated with muscle wasting, such as aging, oxidative stress, and mitochondrial dysfunction. However, the functional significance and mechanism of miR-141-3p in myogenic differentiation have not been explored to date. In this study, we investigated the roles of miR-141-3p on CFL2 expression, proliferation, and myogenic differentiation in C2C12 myoblasts. MiR-141-3p appeared to target the 3'UTR of CFL2 directly and suppressed the expression of CFL2, an essential factor for actin filament (F-actin) dynamics. Transfection of miR-141-3p mimic in myoblasts increased F-actin formation and augmented nuclear Yes-associated protein (YAP), a key component of mechanotransduction. Furthermore, miR-141-3p mimic increased myoblast proliferation and promoted cell cycle progression throughout the S and G2/M phases. Consequently, miR-141-3p mimic led to significant suppressions of myogenic factors expression, such as MyoD, MyoG, and MyHC, and hindered the myogenic differentiation of myoblasts. Thus, this study reveals the crucial role of miR-141-3p in myogenic differentiation via CFL2-YAP-mediated mechanotransduction and provides implications of miRNA-mediated myogenic regulation in skeletal muscle homeostasis.

• Kyungpook Mathematical Journal
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• v.48 no.1
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• pp.15-24
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• 2008

Let $N{\geq}1$ and p > 1. Let ${\Omega}$ be a domain of $\mathbb{R}^N$. In this article we shall establish Kato's inequalities for quasilinear degenerate elliptic operators of the form $A_pu$ = divA(x,$\nabla$u) for $u{\in}K_p({\Omega})$, ), where $K_p({\Omega})$ is an admissible class and $A(x,\xi)\;:\;{\Omega}{\times}\mathbb{R}^N{\rightarrow}\mathbb{R}^N$ is a mapping satisfying some structural conditions. If p = 2 for example, then we have $K_2({\Omega})\;= \;\{u\;{\in}\;L_{loc}^1({\Omega})\;:\;\partial_ju,\;\partial_{j,k}^2u\;{\in}\;L_{loc}^1({\Omega})\;for\;j,k\;=\;1,2,{\cdots},N\}$. Then we shall prove that $A_p{\mid}u{\mid}\;\geq$ (sgn u) $A_pu$ and $A_pu^+\;\geq\;(sgn^+u)^{p-1}\;A_pu$ in D'(${\Omega}$) with $u\;\in\;K_p({\Omega})$. These inequalities are called Kato's inequalities provided that p = 2. The class of operators $A_p$ contains the so-called p-harmonic operators $L_p\;=\;div(\mid{{\nabla}u{\mid}^{p-2}{\nabla}u)$ for $A(x,\xi)={\mid}\xi{\mid}^{p-2}\xi$.

• Journal of Korean Clinical Health Science
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• v.8 no.2
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• pp.1450-1461
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• 2020

Purpose: The purpose of this study was to understand the degree of nursing professional intuition, major satisfaction, clinical practice satisfaction, self-leadership, and career preparation behavior of nursing college students, and to identify factors that influence career preparation behavior. Method: This study was a descriptive research study to analyze the factors affecting career preparation behavior. The data collection period was from August 03 to 30, 2020 for 4 weeks. The survey conducted an online survey of 220 students in grades 3-4 who were enrolled in 6 nursing departments located in P metropolitan city and G province, and have clinical practice experience. The collected data were analyzed using SPSS Win 20.0 program. Results: Career preparation behavior had a significant positive correlation with nursing professional intuition(r=.455, p<.001) and self-leadership(r=.539, p<.001), and major satisfaction(r=-.337, p<.001) and clinical practice satisfaction(r=-.380, p<.001) had a significant negative correlation. Self-leadership(β=.424, p<.001) was the most significant factor influencing the study subjects' career preparation behavior, nursing professional intuition(β=.170, p=.010), clinical practice Satisfaction(β=.127, p=.047), employment information(β=.122, p=.023), major satisfaction(β=.137, p=.042) in the order, these variables were found in the order of The explanatory power of the factors affecting the subject's career preparation behavior was 40.2%. Conclusion: Therefore, in order to help nursing students' career preparation behavior, a strategy to provide a variety of employment information and a strategy for nursing intervention that can improve self-leadership, clinical practice satisfaction, and major satisfaction is required.